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Sugata Kenji  菅田 謙治

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SUGATA Kenji  菅田 謙治

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Researcher Number 10650616
Other IDs
Affiliation (Current) 2025: 熊本大学, ヒトレトロウイルス学共同研究センター, 講師
Affiliation (based on the past Project Information) *help 2025: 熊本大学, ヒトレトロウイルス学共同研究センター, 講師
2023: 熊本大学, ヒトレトロウイルス学共同研究センター, 講師
2022: 熊本大学, ヒトレトロウイルス学共同研究センター, 特別研究員
2020 – 2021: 熊本大学, ヒトレトロウイルス学共同研究センター, 特定事業研究員
2014 – 2015: 京都大学, ウイルス研究所, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 49060:Virology-related / Basic Section 54030:Infectious disease medicine-related / 0803:Pathology, infection/immunology, and related fields / Virology
Keywords
Principal Investigator
HTLV-1 / Tax / HTLV1 / 細胞障害性T細胞 / 成人T細胞白血病 / CTL / 抗原特異的T細胞 / 特異的CD8T細胞 / HLA-A24 / HAM … More / HAM/TSP / TCR / T細胞受容体 / 特異的T細胞 / 次世代シークエンス解析 / CD8 T細胞 / HLA class-I / HTLV-1関連脊髄症(HAM) / 成人T細胞白血病(ATL) / 高親和性T細胞受容体(TCR) / ワクチン / HBZ特異的CTL / 遺伝子組換えワクシニアウイルス / HBZ Less
  • Research Projects

    (4 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (4 People)
  •  HBZ発現マウスを用いたTCRシグナルを介した腫瘍化機構の解明Principal Investigator

    • Principal Investigator
      菅田 謙治
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Kumamoto University
  •  Characterization of HTLV-1 specific CTLs detected in HAM patientsPrincipal Investigator

    • Principal Investigator
      Sugata Kenji
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54030:Infectious disease medicine-related
    • Research Institution
      Kumamoto University
  •  Comprehensive detection of high affinity TCRs specific for HTLV-1Principal Investigator

    • Principal Investigator
      Sugata Kenji
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0803:Pathology, infection/immunology, and related fields
    • Research Institution
      Kumamoto University
  •  Characterization of HBZ specific T cells for new anti-HTLV-1 therapyPrincipal Investigator

    • Principal Investigator
      SUGATA Kenji
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Kyoto University

All 2024 2023 2022 2021 2016 2015 2014

All Journal Article Presentation Book Patent

  • [Book] HTLV-1による成人T細胞白血病・リンパ腫の発症機構2023

    • Author(s)
      菅田謙治, 佐藤賢文
    • Total Pages
      6
    • Publisher
      日本臨牀 81 (増刊号3)
    • Data Source
      KAKENHI-PROJECT-21K08494
  • [Journal Article] HIV-Tocky system to visualize proviral expression dynamics2024

    • Author(s)
      O, Reda., K, Monde., K, Sugata., A, Rahman., W, Sakhor., SA, Rajib., SN, Sithi., BJY, Tan., K, Niimura., C, Motozono., K, Maeda., M, Ono., H, Takeuchi and Y, Satou. 4.巻 7
    • Journal Title

      Communications biology

      Volume: 7 Issue: 1 Pages: 334-350

    • DOI

      10.1038/s42003-024-06025-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KK0277, KAKENHI-PROJECT-21K08494, KAKENHI-PROJECT-23K24139
  • [Journal Article] Association of Clostridium butyricum Therapy Using the Live Bacterial Product CBM588 with the Survival of Patients with Lung Cancer Receiving Chemoimmunotherapy Combinations2023

    • Author(s)
      Tomiya Y, Sakata S, Imamura K, Iyama S, Jodai T, et al.
    • Journal Title

      Cancers

      Volume: 16 Issue: 1 Pages: 47-47

    • DOI

      10.3390/cancers16010047

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16449, KAKENHI-PROJECT-22KK0277, KAKENHI-PROJECT-22K08256, KAKENHI-PROJECT-21K08494, KAKENHI-PROJECT-18K15928, KAKENHI-PROJECT-21H02788, KAKENHI-PROJECT-23K24139
  • [Journal Article] Immunopathology of HTLV-1-Associated Adult T-Cell Leukemia/Lymphoma: A Comprehensive Review.2023

    • Author(s)
      Nakahata S, Enriquez-Vera D, Jahan MI, Sugata K, Satou Y.
    • Journal Title

      Biomolecules

      Volume: 13 Issue: 10 Pages: 1543-1543

    • DOI

      10.3390/biom13101543

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07172, KAKENHI-PROJECT-21K08494
  • [Journal Article] HTLV-1 persistence and leukemogenesis: A game of hide-and-seek with the host immune system2022

    • Author(s)
      Tan Benjy J. Y.、Sugata Kenji、Ono Masahiro、Satou Yorifumi
    • Journal Title

      Frontiers in Immunology

      Volume: 13 Pages: 01-12

    • DOI

      10.3389/fimmu.2022.991928

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08494, KAKENHI-PROJECT-20H03724, KAKENHI-PUBLICLY-21H00433, KAKENHI-PROJECT-22K20776
  • [Journal Article] HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma2021

    • Author(s)
      Tan Benjy J.Y.、Sugata Kenji et al.
    • Journal Title

      Journal of Clinical Investigation

      Volume: 131 Issue: 24

    • DOI

      10.1172/jci150472

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K22783, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-20H03724, KAKENHI-PROJECT-20K07700, KAKENHI-PROJECT-21K08386, KAKENHI-PROJECT-21K08494
  • [Journal Article] HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T cell Immunoglobulin and ITIM Domain (TIGIT).2016

    • Author(s)
      Yasuma K, Yasunaga JI, Takemoto K, Sugata K, Takenouchi N, Nakagawa M, Suzuki Y, and Matsuoka M.
    • Journal Title

      PLoS Pathogens

      Volume: 12 Issue: 1 Pages: e1005372-e1005372

    • DOI

      10.1371/journal.ppat.1005372

    • NAID

      120005763385

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460554, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-13J05302, KAKENHI-PROJECT-14J03189, KAKENHI-PROJECT-26860301, KAKENHI-PROJECT-25293219
  • [Journal Article] Protective effect of cytotoxic T lymphocytes targeting HTLV-1 bZIP factor.2015

    • Author(s)
      Sugata K, Yasunaga JI, Mitobe Y, Miura M, Miyazato P, Kohara M, and Matsuoka M.
    • Journal Title

      Blood

      Volume: 126 Issue: 9 Pages: 1095-1105

    • DOI

      10.1182/blood-2015-04-641118

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460554, KAKENHI-PROJECT-15H04739, KAKENHI-PROJECT-13J05302, KAKENHI-PROJECT-26860301, KAKENHI-PROJECT-25293219
  • [Journal Article] HTLV-1感染の疫学と病原性発現機構2015

    • Author(s)
      菅田謙治、松岡雅雄
    • Journal Title

      日本臨床

      Volume: 1087 Pages: 49-54

    • Data Source
      KAKENHI-PROJECT-26860301
  • [Patent] 抗原ペプチド、核酸、ベクター、HLA/抗原ペプチド複合体、検出試薬、医薬組成物2023

    • Inventor(s)
      佐藤賢文、菅田謙治
    • Industrial Property Rights Holder
      佐藤賢文、菅田謙治
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-178883
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-21K08494
  • [Patent] HTLV-1関連疾患の予防及び/又は治療用ワクチン2014

    • Inventor(s)
      松岡雅雄・菅田謙治
    • Industrial Property Rights Holder
      国立大学法人京都大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-07-31
    • Acquisition Date
      2016-03-10
    • Data Source
      KAKENHI-PROJECT-26860301
  • [Presentation] HLA-A24拘束性の異なるTaxエピトープを認識する特異的TCRの解析2023

    • Author(s)
      菅田謙治, Benjy Tan Jek Yang, 高鳥光徳, Md Belal Hossain, Rajib Md Samiul Alam, Omnia Reda, 徳永雅仁, 野村隼也, 増田曜章, 中島誠, 佐藤知雄, 植田光晴, 宇都宮與, 山野嘉久, 佐藤賢文
    • Organizer
      第9回 日本HTLV-1学会
    • Data Source
      KAKENHI-PROJECT-21K08494
  • [Presentation] Single cell analysis of cerebrospinal cord fluid (CSF) revealed expansion of anti-viral CTLs in HTLV-1-associated myelopathy patients2023

    • Author(s)
      Kenji Sugata
    • Organizer
      2nd Oxford-Kumamoto U Joint Symposium
    • Data Source
      KAKENHI-PROJECT-21K08494
  • [Presentation] Integrated single cell analysis of HTLV-1 specific CD8 T cells in peripheral blood and cerebrospinal fluid from HAM patients2022

    • Author(s)
      Kenji Sugata
    • Organizer
      23rd KUMAMOTO AIDS Seminar
    • Data Source
      KAKENHI-PROJECT-21K08494
  • [Presentation] HAM患者末梢血および脳脊髄液のシングルセル解析によるHAM病態解明と疾患サロゲートマーカーの探索研究2022

    • Author(s)
      菅田謙治
    • Organizer
      第8回日本HTLV-1学会
    • Data Source
      KAKENHI-PROJECT-21K08494
  • [Presentation] TCR配列に基づいた末梢血と脳脊髄液中のHTLV-1特異的CD8+T細胞の包括的解析2021

    • Author(s)
      菅田謙治
    • Organizer
      第7回HTLV-1学会
    • Data Source
      KAKENHI-PROJECT-20K22783
  • [Presentation] TCR配列に基づいた末梢血と脳脊髄液中のHTLV-1特異的CD8+T細胞の包括的解析2021

    • Author(s)
      菅田謙治
    • Organizer
      第7回HTLV-1学会
    • Data Source
      KAKENHI-PROJECT-21K08494
  • [Presentation] HBZはCCR4発現を誘導する2015

    • Author(s)
      菅田謙治、安永純一朗、古田梨愛、松岡雅雄
    • Organizer
      第2回日本HTLV-1学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-26860301
  • [Presentation] Anti-CCR4 antibody activates virus-specific immune response in STLV-1 infected Japanese monkey2015

    • Author(s)
      Kenji Sugata, Junichirou Yasunaga, Kisato Nosaka and Masao Matsuoka
    • Organizer
      17th International Conference on Human Retrovirology : HTLV & Related Viruses
    • Place of Presentation
      France, Martinique
    • Year and Date
      2015-06-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860301
  • [Presentation] Anti-CCR4抗体はTregと感染細胞を同時に標的にすることで、STLV-1自然感染ニホンザルでのウイルス特異的免疫反応を活性化させる2014

    • Author(s)
      菅田謙治, 安永純一朗, 三浦未知, 明里宏文, 小柳義夫, 小原道法, 松岡雅雄
    • Organizer
      日本ウイルス学会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-11
    • Data Source
      KAKENHI-PROJECT-26860301
  • 1.  NAKAHATA Singo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  安永 純一朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 3.  坂田 晋也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  本園 千尋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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