Nomura Takeshi 野村健

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NOMURA Takeshi 野村健

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Researcher Number	10706790
Other IDs	https://orcid.org/0000-0001-8955-3426
Affiliation (Current)	2025: 兵庫県立大学, 環境人間学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 兵庫県立大学, 環境人間学部, 准教授 2015 – 2017: 九州栄養福祉大学, リハビリテーション学部, 准教授 2014: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator General physiology / Basic Section 48020:Physiology-related / 0701:Biology at molecular to cellular levels, and related fields
Keywords	Principal Investigator パッチクランプ / MscL / 機械受容チャネル / 大腸菌 / タンパク質-脂質相互作用 / メカノセンサー / 両親媒性物質 / イオンチャネル / 分子動力学シミュレーション / 膜張力 … More / 電気生理学 / パッチクランプ法 / 細胞膜張力 / 細菌 / クロルプロマジン / Panx1 / 機械刺激 / パネキシン1 / ヘミチャネル / 膜電位 / 機械受容 / ゲーティングキネティクス / パネキシン Less

Elucidation of the gating mechanism of mechanosensitive channel by mechanical stimulation and amphipathic moleculesPrincipal Investigator
- Principal Investigator
  
  野村健
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  University of Hyogo
Molecular mechanisms of lipid-protein interactions focusing on tension-sensing amino acidsPrincipal Investigator
- Principal Investigator
  
  Nomura Takeshi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0701:Biology at molecular to cellular levels, and related fields
- Research Institution
  University of Hyogo
Activation mechanism of bacterial mechanosensitive channel of MscL by amphipathPrincipal Investigator
- Principal Investigator
  
  野村健
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyushu Nutrition Welfare University
Activation mechanism of Pannexin 1 channel by using patch-fluorometryPrincipal Investigator
- Principal Investigator
  
  NOMURA Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyushu Nutrition Welfare University
  Kyoto Prefectural University of Medicine

All 2023 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] A novel force transduction pathway from a tension sensor to the gate in the mechano-gating of MscL channel2023
- Author(s)
  Sawada Y, Nomura T, Martinac B, Sokabe M
- Journal Title
  
  Frontiers in Chemistry
  
  Volume: 11 Pages: 1175443-1175443
- DOI
  10.3389/fchem.2023.1175443
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06847
[Journal Article] Current-direction/amplitude-dependent single channel gating kinetics of mouse pannexin 1 channel: a new concept for gating kinetics2017
- Author(s)
  Nomura Takeshi、Taruno Akiyuki、Shiraishi Makoto、Nakahari Takashi、Inui Toshio、Sokabe Masahiro、Eaton Douglas C.、Marunaka Yoshinori
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 10512-10512
- DOI
  10.1038/s41598-017-10921-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15181, KAKENHI-PROJECT-17K08556
[Journal Article] Voltage dependent inactivation of MscS occurs independently of positively charged residues in the transmembrane domain2016
- Author(s)
  Nomura T, Sokabe M, Yoshimura Y
- Journal Title
  
  Biomed Res Internatl
  
  Volume: 2016 Pages: 2401657-2401657
- DOI
  10.1155/2016/2401657
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05936, KAKENHI-PROJECT-26460300
[Journal Article] Hidden Markov analysis of improved bandwidth mechanosensitive ion channel data2015
- Author(s)
  Almanjahie IM, Khan RN, Milne RK, Nomura T and Martinac B
- Journal Title
  
  Eur Biophys J.
  
  Volume: 44 Issue: 7 Pages: 545-56
- DOI
  10.1007/s00249-015-1060-7
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460300
[Journal Article] Unidirectional incorporation of a bacterial mechanosensitive channel into liposomal membranes2015
- Author(s)
  Nomura T, Cox CD, Bavi N, Sokabe M and Martinac B
- Journal Title
  
  FASEB J.
  
  Volume: 29 Issue: 10 Pages: 4334-45
- DOI
  10.1096/fj.15-275198
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460300, KAKENHI-INTERNATIONAL-15K21745, KAKENHI-ORGANIZER-15H05935, KAKENHI-PLANNED-15H05936, KAKENHI-PROJECT-24247028
[Presentation] 機械受容チャネル分子内のメカノトランスダクション機構：機械刺激受容とゲート開口を仲介する新しい力伝達機構の発見2023
- Author(s)
  曽我部正博、澤田康之、野村健
- Organizer
  岡崎生理学研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K06847
[Presentation] Molecular dynamics study for exploring the force transmission pathway in the bacterial mechanosensitive channel MscL2018
- Author(s)
  Yasuyuki Sawada, Takeshi Nomura and Masahiro Sokabe
- Organizer
  Biophysical Society 62th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08556
[Presentation] Structural Dynamics of the MscL C-terminal domain2017
- Author(s)
  Adam D. Martinac, Navid Bavi, Marien D. Cortes, Omid Bavi, Takeshi Nomura, Boris Martinac, and Eduardo Perozo
- Organizer
  Biophysical Society 61th Annual Meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460300
[Presentation] Molecular Dynamics Analysis on the Force Transmission Pathway via Inter-Subunit Pathway for Mechano-Gating of Bacterial Mechanosensitive Channel MscL2017
- Author(s)
  Yasuyuki Sawada, Takeshi Nomura, and Masahiro Sokabe
- Organizer
  Biophysical Society 61th Annual Meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460300
[Presentation] Pannexin 1チャネルゲーティングは自らの単一チャネル電流の向き・大きさに依存する2017
- Author(s)
  白石真土、野村健、樽野陽幸、丸中良典
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26460300
[Presentation] Current-direction/amplitude-dependent single channel gating kinetics of Pannexin 1 channel2016
- Author(s)
  Nomura T, Shiraishi M, Taruno A, Sokabe M, and Marunaka Y
- Organizer
  International Symposium on Ion Channels, Transporters and Signal Transduction
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460300
[Presentation] Pannexin 1の単一イオンチャネルゲーティングキネティクスの膜電位依存性2014
- Author(s)
  野村健、樽野陽幸、中張隆司、曽我部正博、丸中良典
- Organizer
  第107回近畿生理学談話会
- Place of Presentation
  神戸
- Year and Date
  2014-10-25
- Data Source
  KAKENHI-PROJECT-26460300
[Presentation] Pannexin 1の単一イオンチャネルゲーティングキネティクス解析2014
- Author(s)
  野村健、樽野陽幸、中張隆司、曽我部正博、丸中良典
- Organizer
  生理研研究会　『粘膜免疫学と膜輸送生理学の融合』
- Place of Presentation
  岡崎
- Year and Date
  2014-10-28
- Data Source
  KAKENHI-PROJECT-26460300
[Presentation] Single-channel gating kinetic analysis of mouse pannexin 1 channel
- Author(s)
  Takeshi Nomura, Akiyuki Taruno, Takashi Nakahari, Masahiro Sokabe and Yoshinori Marunaka
- Organizer
  上皮バリア・輸送に関するシンポジウム
- Place of Presentation
  滋賀
- Year and Date
  2014-11-01 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26460300
[Presentation] Voltage-dependent single-channel gating kinetics of mouse pannexin 1 channel
- Author(s)
  Takeshi Nomura, Akiyuki Taruno, Takashi Nakahari, Masahiro Sokabe and Yoshinori Marunaka
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-26460300

1. 澤田康之 (90718355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 樽野陽幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 曽我部正博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nomura Takeshi 野村 健

NOMURA Takeshi 野村 健

Research Projects

Research Products

Co-Researchers

Elucidation of the gating mechanism of mechanosensitive channel by mechanical stimulation and amphipathic moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of lipid-protein interactions focusing on tension-sensing amino acidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Activation mechanism of bacterial mechanosensitive channel of MscL by amphipathPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Activation mechanism of Pannexin 1 channel by using patch-fluorometryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A novel force transduction pathway from a tension sensor to the gate in the mechano-gating of MscL channel2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Current-direction/amplitude-dependent single channel gating kinetics of mouse pannexin 1 channel: a new concept for gating kinetics2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Voltage dependent inactivation of MscS occurs independently of positively charged residues in the transmembrane domain2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hidden Markov analysis of improved bandwidth mechanosensitive ion channel data2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unidirectional incorporation of a bacterial mechanosensitive channel into liposomal membranes2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 機械受容チャネル分子内のメカノトランスダクション機構：機械刺激受容とゲート開口を仲介する新しい力伝達機構の発見2023

Author(s)

Organizer

Data Source

[Presentation] Molecular dynamics study for exploring the force transmission pathway in the bacterial mechanosensitive channel MscL2018

Author(s)

Organizer

Data Source

[Presentation] Structural Dynamics of the MscL C-terminal domain2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Molecular Dynamics Analysis on the Force Transmission Pathway via Inter-Subunit Pathway for Mechano-Gating of Bacterial Mechanosensitive Channel MscL2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Pannexin 1チャネルゲーティングは自らの単一チャネル電流の向き・大きさに依存する2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Nomura Takeshi 野村健

NOMURA Takeshi 野村健