Senda Miki 千田美紀

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SENDA Miki 千田美紀

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Researcher Number	10707467
Other IDs
Affiliation (Current)	2025: 大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 特任助教
Affiliation (based on the past Project Information) *help	2024: 大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 特任助教 2018 – 2020: 大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 特任助教 2014 – 2015: 大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 43020:Structural biochemistry-related / Structural biochemistry
Keywords	Principal Investigator X線結晶構造解析 / タンパク質の結晶化 / LTTR / LysRタイプ転写調節因子 / 全長LTTR-DNA複合体のX線結晶構造解析 / 転写 / LysRタイプ転写因子 / DNA複合体 / 結晶構造 / タンパク質ーDNA複合体 … More / 転写調節因子 / 結晶化スクリーニング / タンパク質結晶化 / 結晶化の再現性向上 / 嫌気チャンバー / 嫌気条件下での結晶化 Less

カルモジュリン依存型キナーゼの活性化機構の構造学的解明と心不全治療薬への応用Principal Investigator
- Principal Investigator
  
  千田美紀
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  High Energy Accelerator Research Organization
Crystal structure analysis of LTTR-DNA complexPrincipal Investigator
- Principal Investigator
  
  Senda Miki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  High Energy Accelerator Research Organization
Anaerobic crystallization for protein crystallizationPrincipal Investigator
- Principal Investigator
  
  SENDA Miki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  High Energy Accelerator Research Organization

All 2021 2020 2019 2018 2016 2015 2014

All Journal Article Presentation

[Journal Article] Crystal structure of the full-length LysR-type transcription regulator2021
- Author(s)
  Giannopoulou EA, Senda M, Koentjoro MP, Adachi N, Ogawa N, Senda T.
- Journal Title
  
  FEBS J.
  
  Volume: － Issue: 15 Pages: 4560-4575
- DOI
  10.1111/febs.15764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03197, KAKENHI-PROJECT-18K06098
[Journal Article] Macromolecular Crystallography Using Long Wavelength X-ray2020
- Author(s)
  松垣直宏, 山田悠介, 引田理英, 平木雅彦, 千田美紀, 千田俊哉
- Journal Title
  
  Nihon Kessho Gakkaishi
  
  Volume: 62 Issue: 1 Pages: 56-61
- DOI
  10.5940/jcrsj.62.56
- NAID
  130007806198
- ISSN
  0369-4585, 1884-5576
- Year and Date
  2020-02-29
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06098
[Journal Article] Structural basis for highly (S)-enantioselective reductase towards aliphatic ketones with only one carbon difference between side chain2019
- Author(s)
  Koesoema, A., Sugiyama, Y., Xu, Z., Standley, D. M., Senda, M., Senda, T. & Matsuda, T.
- Journal Title
  
  Applied Microbiology and Biotechnology
  
  Volume: 103 Issue: 23-24 Pages: 9543-9553
- DOI
  10.1007/s00253-019-10093-w
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06098
[Journal Article] Reversible control of enantioselectivity by the length of ketone substituent in biocatalytic reduction2019
- Author(s)
  Koesoema, A., Sugiyama, Y., Sriwong, K. T. Xu, Z., Verina, S. Standley, D. M., Senda, M., Senda, T. & Matsuda, T.
- Journal Title
  
  Applied Microbiology and Biotechnology
  
  Volume: 103 Issue: 23-24 Pages: 9529-9541
- DOI
  10.1007/s00253-019-10206-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06098
[Journal Article] Crystal Structure of the DNA-binding Domain of the LysR-type Transcriptional Regulator CbnR in Complex with a DNA Fragment of the Recognition-binding Site2018
- Author(s)
  千田美紀, 安達成彦, 千田俊哉, Maharani Pertiwi Koentjoro, 小川直人
- Journal Title
  
  Nihon Kessho Gakkaishi
  
  Volume: 60 Issue: 2-3 Pages: 135-141
- DOI
  10.5940/jcrsj.60.135
- NAID
  130007383391
- ISSN
  0369-4585, 1884-5576
- Year and Date
  2018-05-31
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06098
[Journal Article] Structural and computational bases for dramatic skeletal rearrangement in anditomin biosynthesis2018
- Author(s)
  Nakashima, Y., Mitsuhashi, T., Matsuda, Y., Senda, M., Sato, H., Yamazaki, M., Uchiyama, M., Senda, T. & Abe, I.
- Journal Title
  
  JACS
  
  Volume: 140 Issue: 30 Pages: 9743-9750
- DOI
  10.1021/jacs.8b06084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06098, KAKENHI-PLANNED-16H06443, KAKENHI-PLANNED-16H06454, KAKENHI-PUBLICLY-17H05430, KAKENHI-PROJECT-17H06264, KAKENHI-PROJECT-17J09712
[Journal Article] Crystal structure of the DNA-binding domain of the LysR-type transcriptional regulator CbnR in complex with a DNA fragment of the recognition-binding site in the promoter region.2018
- Author(s)
  Koentjoro MP, Adachi N, Senda M, Ogawa N, Senda T.
- Journal Title
  
  FEBS J.
  
  Volume: 285(5) Issue: 5 Pages: 977-989
- DOI
  10.1111/febs.14380
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07321, KAKENHI-PROJECT-18K06098, KAKENHI-PROJECT-17H06264
[Journal Article] The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.2016
- Author(s)
  Sumita, K., Lo, Y., Takeuchi, K., Senda, M., Kofuji, S., Ikeda, Y., Terakawa, J., Sasaki, M., Yoshino, H., Majd, N., Zheng, Y., Kahoud, E. R., Yokota, T., Emerling, B. M., Asara, J. M., Ishida, T., Locasale, J. W., Daikoku, T., Anastasiou, D., Senda & T., Sasaki, A. T.
- Journal Title
  
  Molecular Cell
  
  Volume: 61 Issue: 2 Pages: 1-12
- DOI
  10.1016/j.molcel.2015.12.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26650026
[Journal Article] Improvement of Helicobacter pylori CagA crystals by the multi-step soaking method2016
- Author(s)
  Senda, M.
- Journal Title
  
  Cryst. Growth Des.
  
  Volume: 16 Issue: 3 Pages: 1565-1571
- DOI
  10.1021/acs.cgd.5b01692
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-22114001, KAKENHI-PROJECT-25250016, KAKENHI-PROJECT-26650026, KAKENHI-PROJECT-26860284, KAKENHI-PROJECT-16H06373, KAKENHI-PROJECT-16K15273
[Journal Article] Crystallization and preliminary crystallographic analysis of acetophenone reductase from Geotrichum candidum NBRC 45972015
- Author(s)
  Y. Sugiyama, M. Senda, T. Senda, T. Matsuda
- Journal Title
  
  Acta Crystallogr.
  
  Volume: F71 Issue: 3 Pages: 320-323
- DOI
  10.1107/s2053230x15002265
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25410189, KAKENHI-PROJECT-26650026
[Journal Article] Molecular mechanism of strict substrate specificity of an extradiol dioxygenase, DesB, derived from Sphingobium sp. SYK-6.2014
- Author(s)
  K. Sugimoto, M. Senda, D. Kasai, E. Masai, M. Fukuda and T. Senda
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26650026
[Journal Article] Complete pyridine-nucleotide-specific conversion of an NADH-dependent ferredoxin reductase2014
- Author(s)
  Nishizawa A, Harada A, Senda M, Tachihara Y, Muramatsu D, Kishigami S, Mori S, Sugiyama K, Senda T, Kimura S
- Journal Title
  
  Biochemical Journal
  
  Volume: 462 Issue: 2 Pages: 257-265
- DOI
  10.1042/bj20140384
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J04356, KAKENHI-PROJECT-26650026
[Presentation] 良質なタンパク質結晶と回折データを効率的に得るための戦略2020
- Author(s)
  千田美紀
- Organizer
  日本結晶学会令和2年度年会
- Data Source
  KAKENHI-PROJECT-18K06098
[Presentation] Comprehensive strategy for quick determination of protein structures.2020
- Author(s)
  Miki Senda
- Organizer
  American Crystallographic Association (ACA) 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06098
[Presentation] 良質なタンパク質結晶を得るための戦略2019
- Author(s)
  千田美紀
- Organizer
  平成30年度第2回構造生物学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06098
[Presentation] タンパク質結晶化の総合戦略2019
- Author(s)
  千田美紀、千田俊哉
- Organizer
  第19回蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06098
[Presentation] Comprehensive strategy for efficient generation of well-diffracted crystals2019
- Author(s)
  Miki Senda, Toshiya Senda
- Organizer
  ACA2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06098
[Presentation] Crystallization strategy when no crystals are obtained in the initial screening,2018
- Author(s)
  Miki Senda, Toshiya Senda
- Organizer
  Structural Biology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06098
[Presentation] Crystallization strategy when no well-diffracted crystals are obtained in the crystallization screening.2018
- Author(s)
  Miki Senda, Toshiya Senda
- Organizer
  American Crystallographic Association (ACA) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06098
[Presentation] 良質なタンパク質結晶と回折データを効率的に得るための戦略2018
- Author(s)
  千田美紀、千田俊哉
- Organizer
  結晶学会平成30年度年会
- Data Source
  KAKENHI-PROJECT-18K06098
[Presentation] A comprehensive strategy to obtain high quality crystals.2015
- Author(s)
  Miki Senda, Toshiya Senda
- Organizer
  American Crystallographic Association (ACA) 2015
- Place of Presentation
  フィラデルフィア（米国）
- Year and Date
  2015-07-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26650026
[Presentation] 嫌気条件下で結晶化の成功率を高める手法2015
- Author(s)
  千田美紀、千田俊哉
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26650026
[Presentation] タンパク質結晶の質を効率良く改善するための結晶工学的処理の手法2015
- Author(s)
  千田美紀, 千田俊哉
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  あわぎんホール（徳島県徳島市）
- Year and Date
  2015-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-26650026
[Presentation] Anaerobic crystallization for protein crystallography.2014
- Author(s)
  千田美紀
- Organizer
  23rd Congress of the IUCr
- Place of Presentation
  Palais des Congres de Montreal (カナダ、モントリオール）
- Year and Date
  2014-08-11
- Data Source
  KAKENHI-PROJECT-26650026
[Presentation] 嫌気条件下でのタンパク質結晶化2014
- Author(s)
  千田美紀
- Organizer
  第14回日本蛋白質科学会
- Place of Presentation
  ワークピア横浜（神奈川県横浜市）
- Year and Date
  2014-06-26
- Data Source
  KAKENHI-PROJECT-26650026
[Presentation] フェレドキシン還元酵素BphA4の酸化還元状態依存的な構造変化と親和性調節の解明2014
- Author(s)
  千田美紀
- Organizer
  日本結晶学会平成26年度年会
- Place of Presentation
  東京大学農学部（東京都文京区）
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-26650026

1. 松田知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 安達成彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Senda Miki 千田 美紀

SENDA Miki 千田 美紀

Research Projects

Research Products

Co-Researchers

カルモジュリン依存型キナーゼの活性化機構の構造学的解明と心不全治療薬への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Crystal structure analysis of LTTR-DNA complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Anaerobic crystallization for protein crystallizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Crystal structure of the full-length LysR-type transcription regulator2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Macromolecular Crystallography Using Long Wavelength X-ray2020

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Structural basis for highly (S)-enantioselective reductase towards aliphatic ketones with only one carbon difference between side chain2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reversible control of enantioselectivity by the length of ketone substituent in biocatalytic reduction2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal Structure of the DNA-binding Domain of the LysR-type Transcriptional Regulator CbnR in Complex with a DNA Fragment of the Recognition-binding Site2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Structural and computational bases for dramatic skeletal rearrangement in anditomin biosynthesis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structure of the DNA-binding domain of the LysR-type transcriptional regulator CbnR in complex with a DNA fragment of the recognition-binding site in the promoter region.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improvement of Helicobacter pylori CagA crystals by the multi-step soaking method2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystallization and preliminary crystallographic analysis of acetophenone reductase from Geotrichum candidum NBRC 45972015

Author(s)

Journal Title

DOI

Senda Miki 千田美紀

SENDA Miki 千田美紀