ISHIMARU Kayoko 石丸かよ子

Researcher Number	10710353
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 医学研究員
Affiliation (based on the past Project Information) *help	2017 – 2023: 山梨大学, 大学院総合研究部, 助教 2015 – 2016: 山梨大学, 総合研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Collagenous pathology/Allergology
Keywords	Principal Investigator マスト細胞 / アレルギー / 概日時計 / アナフィラキシーショック / 豊かな環境 / アレルギー反応 / 免疫系 / 報酬系 / REV-ERB / SR9009 … More / REV-REB / 脱顆粒 / 時計遺伝子 / 精神的ストレス / ストレス Less

How activation of the reward system inhibits allergic reactionPrincipal Investigator
- Principal Investigator
  
  石丸かよ子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Yamanashi
A putative REE-ERB agonist SR9009 inhibits IgE-mediated mast cell activationPrincipal Investigator
- Principal Investigator
  
  Ishimaru Kayoko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Yamanashi
Regulation of plasma histamine levels by the mast cell clock and its modulation by stressPrincipal Investigator
- Principal Investigator
  
  ISHIMARU Kayoko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  University of Yamanashi
The circadian clock controls systemic anaphylactic reaction by regulating the high-affinity IgE receptor expressed on mast cellsPrincipal Investigator
- Principal Investigator
  
  ISHIMARU Kayoko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  University of Yamanashi

All 2024 2021 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Cha o 3, a cypress pollen allergen, does not activate basophils in Japanese cypress pollinosis2024
- Author(s)
  Kobayashi Yoshiaki、Suzuki Keisuke、Tateno Minoru、Nakamura Yuki、Ishimaru Kayoko、Nagasaka Yuka、Sakurai Daiju、Ohashi-Doi Katsuyo、Nakao Atsuhito
- Journal Title
  
  Journal of Allergy and Clinical Immunology: Global
  
  Volume: 3 Issue: 1 Pages: 100198-100198
- DOI
  10.1016/j.jacig.2023.100198
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08561, KAKENHI-PROJECT-23K08932
[Journal Article] Probiotic Supplementation and Human Milk Cytokine Profiles in Japanese Women: A Retrospective Study from an Open-Label Pilot Study.2021
- Author(s)
  Tomoki Takahashi, Hirofumi Fukudome, Hiroshi M. Ueno, Shiomi Watanabe-Matsuhashi, Taku Nakano, Toshiya Kobayashi, Kayoko Ishimaru, Atsuhito Nakao
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 7 Pages: 2285-2296
- DOI
  10.3390/nu13072285
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08904
[Journal Article] The putatively specific synthetic REV-ARB agonist SR9009 inhibits IgE- and IL-33-mediated mast cell activation independently of the circadian clock.2019
- Author(s)
  Kayoko Ishimaru, Shotaro Nakajima, Guannan Yu, Yuki Nakamura, Atsuhito Nakao
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 24 Pages: 63206031-63206031
- DOI
  10.3390/ijms20246320
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08904, KAKENHI-PROJECT-18K16142
[Journal Article] Differential Day-Night Outcome to HSV-2 Cutaneous Infection2018
- Author(s)
  Matsuzawa T, Nakamura Y, Ogawa Y, Ishimaru K, Goshima F, Shimada S, Nakao A, Kawamura T.
- Journal Title
  
  J Invest Dermatol
  
  Volume: 138 Pages: 233-236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16206
[Journal Article] Induction of colonic regulatory T cells by 5-aminosalicylic acid (5-ASA) by activating the aryl hydrocarbon receptor.2017
- Author(s)
  Oh-oka K, Kojima Y, Uchida K, Yoda M, Ishimaru K, Nakajima S, Hemmi J, Kano H, Fujii-Kuriyama Y, Katoh R, Ito H, Nakao A
- Journal Title
  
  Cell Mol Gastroenterol Hepatol
  
  Volume: 印刷中 Issue: 1 Pages: 135-151
- DOI
  10.1016/j.jcmgh.2017.03.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19573, KAKENHI-PROJECT-15K19607, KAKENHI-PROJECT-17K15935, KAKENHI-PROJECT-15H04864
[Journal Article] <i>Clock</i>-dependent temporal regulation of IL-33/ST2-mediated mast cell response2017
- Author(s)
  Kawauchi T, Ishimaru K, Nakamura Y, Nakano N, Hara M, Ogawa H, Okumura K, Shibata S, Nakao A
- Journal Title
  
  Allergol. Int.
  
  Volume: 66 Issue: 3 Pages: 472-478
- DOI
  10.1016/j.alit.2017.02.004
- NAID
  130005858846
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-15K19573, KAKENHI-PROJECT-15K09784, KAKENHI-PROJECT-15K09548
[Journal Article] Regulation of plasma histamine levels by the mast cell clock and its modulation by stress.2017
- Author(s)
  Nakamura Y, Ishimaru K, Shibata S, Nakao A.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 39934-39934
- DOI
  10.1038/srep39934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-15K19573, KAKENHI-PROJECT-15K09548
[Journal Article] The efficacy of sublingual immunotherapy for allergic rhinitis may vary with the time of day.2016
- Author(s)
  Igarashi S, Suzuki K, Nakamura Y, Ishimaru K, Fukano C, Masuyama K, Ohashi-Doi K, Nakao A
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 171 Issue: 2 Pages: 111-118
- DOI
  10.1159/000450954
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-15K19573
[Journal Article] Inhibition of IgE-mediated allergic reactions by pharmacologically targeting the circadian clock.2015
- Author(s)
  Nakamura Y, Nakano N, Ishimaru K, Ando N, Katoh R, Suzuki-Inoue K, Koyanagki S, Ogawa H, Okumura K, Shibata S, Nakao A
- Journal Title
  
  The Journal of allergy and clinical immunology
  
  Volume: 137(4) Issue: 4 Pages: 1226-1235
- DOI
  10.1016/j.jaci.2015.08.052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09784, KAKENHI-PROJECT-26220201, KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-26670475, KAKENHI-PROJECT-15K19573, KAKENHI-PROJECT-15K09548
[Journal Article] Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice.2015
- Author(s)
  Ando N, Nakamura Y, Aoki R, Ishimaru K, Ogawa H, Okumura K, Shibata S, Shimada S, Nakao A
- Journal Title
  
  J Invest Dermatol
  
  Volume: 135 Issue: 12 Pages: 3001-3008
- DOI
  10.1038/jid.2015.316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19573, KAKENHI-PROJECT-26220201, KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-26461684, KAKENHI-PROJECT-26670475, KAKENHI-PROJECT-26860874, KAKENHI-PROJECT-26293087
[Presentation] 核内受容体REV-ERB特異的合成アゴニスト（SR9009）は概日時計非依存的にマスト細胞の活性化を阻害する2021
- Author(s)
  石丸かよ子
- Organizer
  第6回日本アレルギー学会関東地方会
- Data Source
  KAKENHI-PROJECT-19K08904

1. NAKAO ATSUHITO

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. NAKAMURA Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 中野信浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIMARU Kayoko 石丸 かよ子

Research Projects

Research Products

Co-Researchers

How activation of the reward system inhibits allergic reactionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A putative REE-ERB agonist SR9009 inhibits IgE-mediated mast cell activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of plasma histamine levels by the mast cell clock and its modulation by stressPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The circadian clock controls systemic anaphylactic reaction by regulating the high-affinity IgE receptor expressed on mast cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cha o 3, a cypress pollen allergen, does not activate basophils in Japanese cypress pollinosis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Probiotic Supplementation and Human Milk Cytokine Profiles in Japanese Women: A Retrospective Study from an Open-Label Pilot Study.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The putatively specific synthetic REV-ARB agonist SR9009 inhibits IgE- and IL-33-mediated mast cell activation independently of the circadian clock.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential Day-Night Outcome to HSV-2 Cutaneous Infection2018

Author(s)

Journal Title

Data Source

[Journal Article] Induction of colonic regulatory T cells by 5-aminosalicylic acid (5-ASA) by activating the aryl hydrocarbon receptor.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <i>Clock</i>-dependent temporal regulation of IL-33/ST2-mediated mast cell response2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Regulation of plasma histamine levels by the mast cell clock and its modulation by stress.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The efficacy of sublingual immunotherapy for allergic rhinitis may vary with the time of day.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of IgE-mediated allergic reactions by pharmacologically targeting the circadian clock.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice.2015

Author(s)

Journal Title

DOI

Data Source

ISHIMARU Kayoko 石丸かよ子