Masukawa Daiki 増川太輝

… Alternative Names

MASUKAWA Daiki 増川太輝

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Researcher Number	10711898
Other IDs	https://orcid.org/0000-0002-3094-0058
Affiliation (Current)	2025: 横浜市立大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2024: 横浜市立大学, 医学部, 講師 2018 – 2023: 横浜市立大学, 医学部, 助教 2016 – 2018: 横浜市立大学, 医学部, 助手 2015: 横浜市立大学, 医学(系)研究科(研究院), 特任助手
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Basic Section 48030:Pharmacology-related / Neurochemistry/Neuropharmacology Except Principal Investigator Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related / General pharmacology
Keywords	Principal Investigator GPR143 / L-DOPA / 延髄孤束核 / 大動脈神経 / ドーパ / 延髄弧束核 / NTS / 圧受容器反射 / 下位脳幹弧束核 / グレリン … More / 副交感神経 / 脳内報酬系 / 慢性心不全 / 心筋梗塞 / グルタミン酸 / ドパミン / Tyrosine hydroxylase / vGlut2 / 黒質-線条体 / 中枢性血圧制御 / 線条体 / 神経伝達物質 / 下位脳幹孤束核 / Aortic depressor nerve / Neurotransmitter / 心血管応答中枢 / NMDA / OA1 / primary affarent / blood pressure / 自律神経 / Glutamate … More Except Principal Investigator GPR143 / トランスポーター / L-ドーパ / ドーパ / 神経回路 / シナプス小胞 / L-DOPA / 神経伝達物質 / D2受容体 / ドパミン / ドパミン作動性神経伝達 / 受容体 / 腎不全 / 腎結石 / 心不全 / 肺高血圧 / 眼白子症原因遺伝子 / Gタンパク質連関型受容体 / α1アドレナリン受容体 / 血管平滑筋 / 日内変動 / 血圧 / 生理活性物質 Less

脳内報酬系・副交感神経系に着目した難治性心疾患およびその合併症の画期的治療法開発Principal Investigator
- Principal Investigator
  
  増川太輝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Yokohama City University
The analysis for the circuits of L-DOPA-containing neurons in the central nervous system
- Principal Investigator
  
  GOSHIMA Yoshio
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Yokohama City University
Neural circuits of L-DOPAnergic neurotransmission and their mechanisms of actionPrincipal Investigator
- Principal Investigator
  
  MASUKAWA Daiki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Yokohama City University
The functional analysis of L-DOPA neurotransmission in the nucleus tractus solitariiPrincipal Investigator
- Principal Investigator
  
  Masukawa Daiki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Yokohama City University
Dopa as a neurotransmitter in heart failure and acute kidney injury
- Principal Investigator
  
  Hashimoto Tatsuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kanagawa Dental College
  Yokohama City University
Roles of L-DOPA as a neurotransmitter and L-DOPA reuptake systems involved
- Principal Investigator
  
  GOSHIMA Yoshio
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Yokohama City University
Functional analysis of interaction between DOPA and Glutamate neurotransmission in the nucleus tractus solitariiPrincipal Investigator
- Principal Investigator
  
  MASUKAWA Daiki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yokohama City University
Functional analysis of DOPAergic transmission in cardiovascular system
- Principal Investigator
  
  GOSHIMA Yoshio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yokohama City University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Coupling between GPR143 and dopamine D2 receptor is required for selective potentiation of dopamine D2 receptor function by L-3,4-dihydroxyphenylalanine in the dorsal striatum2023
- Author(s)
  Masukawa D, Kitamura S, Tajika R, Uchimura H, Arai M, Takada Y, Arisawa T, Otaki M, Kanai K, Kobayashi K, Miyazaki T, Goshima Y
- Journal Title
  
  J Neurochem
  
  Volume: 165 Issue: 2 Pages: 177-195
- DOI
  10.1111/jnc.15789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02673, KAKENHI-PROJECT-20K07069, KAKENHI-PROJECT-22H04922
[Journal Article] L-DOPA receptor GPR143 functionally couples with adrenergic α1B receptor at the second transmembrane interface2023
- Author(s)
  Daiki Masukawa、Ryo Takahagi、Yuka Nakao、Yoshio Goshima
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07069
[Journal Article] Involvement of the L-DOPA receptor GPR143 in acute and chronic actions of methylphenidate2023
- Author(s)
  Hiraku Uchimura、Kaori Kanai、Masami Arai、 Miyu Inoue、Akitoyo Hishimoto、Daiki Masukawa、Yoshio Goshima
- Journal Title
  
  Journal of Pharmacological Science
  
  Volume: 152 Pages: 178-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07069
[Journal Article] Right ventricular overloading is attenuated in monocrotaline-induced pulmonary hypertension model rats with a disrupted Gpr143 gene, the gene that encodes the 3,4-l-dihydroxyphenyalanine (l-DOPA) receptor.2022
- Author(s)
  Nakano M, Koga M, Hashimoto T, Matsushita N, Masukawa D, Mizuno Y, Uchimura H, Niikura R, Miyazaki T, Nakamura F, Zou S, Shimizu T, Saito M, Tamura K, Goto T, Goshima Y.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 148 Issue: 2 Pages: 214-220
- DOI
  10.1016/j.jphs.2021.11.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-21H02673, KAKENHI-PROJECT-20K07069, KAKENHI-PROJECT-20K21606, KAKENHI-PROJECT-18K16488, KAKENHI-PROJECT-22H04922
[Journal Article] L-DOPA-Induced Neurogenesis in the Hippocampus Is Mediated Through GPR143, a Distinct Mechanism of Dopamine.2022
- Author(s)
  Kasahara Y, Masukawa D, Kobayashi K, Yamasaki M, Watanabe M, Goshima Y.
- Journal Title
  
  Stem Cells.
  
  Volume: 40 Issue: 2 Pages: 215-226
- DOI
  10.1093/stmcls/sxab013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02673, KAKENHI-PROJECT-21K15272, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03410
[Journal Article] Genetic associations of single nucleotide polymorphisms in the L-DOPA receptor (GPR143) gene with severity of nicotine dependence in Japanese individuals, and attenuation of nicotine reinforcement in Gpr143 gene-deficient mice2020
- Author(s)
  Masukawa D, Nishizawa D, Kanai K, Kitamura S, Kasahara Y, Hashimoto T, Takahagi R, Hasegawa J, Nakayama K, Sato N, Tanioka F, Sugimura H, Ikeda K, Goshima Y
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 144(2) Issue: 2 Pages: 89-93
- DOI
  10.1016/j.jphs.2020.07.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09259, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-18H02580
[Journal Article] Distribution of mRNA for GPR143, a receptor of 3,4-L-dihydroxyphenylalanine, and of immunoreactivities for nicotinic acetylcholine receptors in the nigrostriatal and mesolimbic regions2020
- Author(s)
  Kasahara Yuka、Masukawa Daiki、Nakamura Yoshie、Murata Koshi、Hashimoto Tatsuo、Takizawa Kohtaro、Koga Motokazu、Nakamura Fumio、Fukazawa Yugo、Funakoshi Kengo、Goshima Yoshio
- Journal Title
  
  Neuroscience Research
  
  Volume: - Pages: 370-375
- DOI
  10.1016/j.neures.2020.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KK0190, KAKENHI-PUBLICLY-20H05058, KAKENHI-PROJECT-18H02580, KAKENHI-PROJECT-19H03323
[Journal Article] Genetic associations of single nucleotide polymorphisms in the L-DOPA receptor (GPR143) gene with severity of nicotine dependence in Japanese individuals, and attenuation of nicotine reinforcement in Gpr143 gene-deficient mice2020
- Author(s)
  Masukawa D, Nishizawa D, Kanai K, Kitamura S, Kasahara Y, Hashimoto T, Takahagi R, Hasegawa J, Nakayama K, Sato N, Tanioka F, Sugimura H, Ikeda K, Goshima Y
- Journal Title
  
  J Pharmacol Sci
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14923
[Journal Article] Overexpression of the gene product of ocular albinism 1 (GPR143/OA1) but not its mutant forms inhibits neurite outgrowth in PC12?cells2019
- Author(s)
  Masukawa Daiki、Yamada Kaisei、Goshima Yoshio
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 141 Issue: 1 Pages: 41-48
- DOI
  10.1016/j.jphs.2019.09.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02580
[Journal Article] Immunoreactivity of a G protein-coupled l-DOPA receptor GPR143, in Lewy bodies2019
- Author(s)
  Goshima Yoshio、Watanabe Shuya、Seki Erika、Koga Motokazu、Masukawa Daiki、Nakamura Fumio、Komori Takashi、Arai Nobutaka
- Journal Title
  
  Neuroscience Research
  
  Volume: 148 Pages: 49-53
- DOI
  10.1016/j.neures.2018.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02580
[Journal Article] Overexpression of the gene product of ocular albinism 1 (GPR143/OA1) but not its mutant forms inhibits neurite outgrowth in PC12 cells.2019
- Author(s)
  Masukawa D, Yamada K, Goshima Y
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 141 Pages: 41-48
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14923
[Journal Article] l-DOPA and Its Receptor GPR143: Implications for Pathogenesis and Therapy in Parkinson's Disease.2019
- Author(s)
  Goshima Y, Masukawa D, Kasahara Y, Hashimoto T, Aladeokin AC
- Journal Title
  
  Front Pharmacol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14923
[Journal Article] l-DOPA and Its Receptor GPR143: Implications for Pathogenesis and Therapy in Parkinson’s Disease2019
- Author(s)
  Goshima Yoshio、Masukawa Daiki、Kasahara Yuka、Hashimoto Tatsuo、Aladeokin Aderemi Caleb
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 10 Pages: 1-9
- DOI
  10.3389/fphar.2019.01119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06896, KAKENHI-PROJECT-19K16375, KAKENHI-PROJECT-18H02580
[Journal Article] 分子から迫る神経薬理学　ドーパ受容体候補分子からみるドーパ療法の応用および問題点.2018
- Author(s)
  増川太輝，五嶋良郎
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 36 Pages: 1130-1132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02580
[Journal Article] 分子から迫る神経薬理学　ドーパ受容体の生理学的および薬理学的作用.2018
- Author(s)
  増川太輝，五嶋良郎
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 36 Pages: 1004-1005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02580
[Journal Article] 分子から迫る神経薬理学　ドーパ神経伝達物質仮説：ドーパ受容体は存在するか？2018
- Author(s)
  増川太輝，五嶋良郎
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 36 Pages: 878-879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02580
[Journal Article] L-DOPA sensitizes vasomotor tone by modulating the vascular alpha1-adrenergic receptor2017
- Author(s)
  Masukawa Daiki、Koga Motokazu、Sezaki Anna、Nakao Yuka、Kamikubo Yuji、Hashimoto Tatsuo、Okuyama-Oki Yuki、Aladeokin Aderemi Caleb、Nakamura Fumio、Yokoyama Utako、Wakui Hiromichi、Ichinose Hiroshi、Sakurai Takashi、Umemura Satoshi、Tamura Koichi、Ishikawa Yoshihiro、Goshima Yoshio
- Journal Title
  
  JCI Insight
  
  Volume: 2 Issue: 18 Pages: 1-16
- DOI
  10.1172/jci.insight.90903
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07062, KAKENHI-PROJECT-17K09040, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H04687, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K21273, KAKENHI-PROJECT-15H05761, KAKENHI-PUBLICLY-17H05555, KAKENHI-PROJECT-16H05300
[Journal Article] l-3,4-Dihydroxyphenylalanine induces ptosis through a GPR143-independent mechanism in mice.2016
- Author(s)
  Ueda S, Masukawa D, Koga M, Goshima Y
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 132 Issue: 1 Pages: 109-112
- DOI
  10.1016/j.jphs.2016.08.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] 線条体間接路における L-DOPA の生理学的役割解明2022
- Author(s)
  増川太輝、五嶋良郎
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07069
[Presentation] マウス線条体間接路におけるL-DOPA受容体GPR143は不安様行動を制御する．2022
- Author(s)
  田近伶, 増川太輝, 内村放, 五嶋良郎
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] 背側線条体に発現するL-DOPA受容体GPR143は、ドーパミン D2 受容体作動薬キンピロール応答を正に制御する2022
- Author(s)
  大瀧百々代、増川太輝、五嶋良郎他
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] L-DOPA受容体GPR143はハロペリドールによる錐体外路様症状に関与する．2022
- Author(s)
  荒井柾美, 増川太輝, 北村慧, 大瀧百々代, 五嶋良郎
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] 脱分極刺激誘発性ドーパ及びドパミン遊離に及ぼすドパミン作動薬の効果2022
- Author(s)
  五嶋良郎，青木令奈，岡田貴子，増川太輝
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] L-DOPAは線条体間接路におけるGPR143とドパミンD2受容体間相互作用を介して不安様行動を制御する2022
- Author(s)
  増川太輝，五嶋良郎
- Organizer
  第45回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] L-DOPA受容体GPR143は、GPR143とADRA1Bとのヘテロマー形成によりADRA1Bを介するERK応答を増強する．2022
- Author(s)
  高萩亮, 増川太輝, 五嶋良郎
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] マウス線条体間接路におけるL-DOPA受容体GPR143はD2Rとの連関を介して不安様行動を制御する2022
- Author(s)
  田近伶，増川太輝，内村放，五嶋良郎
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] コリン介在性神経L-DOPA受容体GPR143は，ドパミン D2受容体との機能連関を介してハロペリドールによる錐路様症状を修飾する2022
- Author(s)
  荒井柾美，増川太輝，北村慧，大瀧百々代，五嶋良郎
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] Compound X is a novel ligand candidate for L-DOPA receptor GPR1432022
- Author(s)
  井上美優，椎名勇，増川太輝，五嶋良郎
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] L-DOPA 受容体（GPR143）による血管平滑筋細胞の遊走と増殖はラットにおけるモノクロタリン誘発性肺高血圧に関与する．2022
- Author(s)
  中野雅友樹, 橋本達夫, 古賀資和, 増川太輝, 五嶋良郎他
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] 線条体間接路における L-DOPA の生理学的役割解明．2022
- Author(s)
  増川太輝, 五嶋良郎
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] バフィロマイシンおよびブレフェルディンに対する脱分極刺激誘発性ドーパ及びドパミン遊離の異なる感受性．2022
- Author(s)
  五嶋良郎, 井上美優, 増川太輝, 日浅未来, 表弘志
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] L-DOPA receptor, GPR143, is involved in methylphenidate -induced locomotion in mice.2022
- Author(s)
  内村放, 金井香央里, 増川太輝, 五嶋良郎
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] Functional analysis of GPR143, an L-DOPA receptor, in GPCRs hetero-oligomers2021
- Author(s)
  増川太輝、五嶋良郎
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] ニコチンの効果におけるドーパ受容体GPR143の役割解明．2021
- Author(s)
  高萩亮, 増川太輝, 北村慧, 金井香央里, 笠原由佳, 内村放, 五嶋良郎
- Organizer
  第145回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-21H02673
[Presentation] ニコチンの効果における GPR143の関与および喫煙患者におけるGPR143 の一塩基多型解析2020
- Author(s)
  増川太輝、五嶋良郎　他
- Organizer
  第43回神経科学大会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] GPR143, a L-DOPA receptor, is involved in monocrotaline-induced pulmonary hypertension2020
- Author(s)
  Nakano M, Hashimoto T, Koga M, Masukawa D, Oku S, Mizuno Y, Goto T, Tamura K, Goshima Y
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] 肺高血圧症におけるドーパ性神経伝達機構の解析2020
- Author(s)
  中野雅友樹、橋本達夫、古賀資和、増川太輝、奥真哉、水野祐介、後藤隆久、田村功一、五嶋良郎
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06896
[Presentation] Functional analysis of GPR143, an L-DOPA receptor, in GPCRs hetero-oligomers2020
- Author(s)
  増川太輝、五嶋良郎
- Organizer
  第94回薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07069
[Presentation] Impairment of nicotine-induced behavioral changes in L-DOPA receptor gene (Gpr143)-deficient mice, and genetic associations of single nucleotide polymorphisms in the GPR143 gene with severity of nicotine dependence in Japanese in dividuals2020
- Author(s)
  Daiki Masukawa, Nishiawa Daisuke, Yuka Kasahara, Satoshi Kitamura, Kaori Kanai, Kazutaka Ikeda, Yoshio Goshima
- Organizer
  第43回神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07069
[Presentation] GPR143, an L-DOPA receptor, may help control inflammation in adenine-induced chronic kidney disease2019
- Author(s)
  Tatsuo Hashimoto, Masayuki Nakano, Shota Suzuki, Takayuki Yamada, Daiki Masukawa, Motokazu Koga, Ryuichi Ito, Kotaro Haruhara, Hiromichi Wakui, Koichi Tamura, Yoshio Goshima
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06896
[Presentation] An optogenetic approach to identify L-DOPA as a neurotransmitter in the nucleus tractus solitarii.2019
- Author(s)
  Masukawa M, Nakao Y, Muneto H, Kim R, Bito H, Goshima Y
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] An optogenetic approach for functional analysis of L-DOPAergic neurotransmission in the nucleus tractus solitarii.2019
- Author(s)
  Masukawa D, Nakao Y, Muneto H, Kim R, Bito H, Goshima Y
- Organizer
  第42回日本神経科学大会・第62回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] ドーパ受容体 GPR143 遺伝子欠損マウスにおけるニコチンの効果および喫煙患者における GPR143 の一塩基多型解析.2019
- Author(s)
  増川太輝, 西澤大輔, 笠原由佳，北村慧，金井香央里，池田和隆, 五嶋良郎
- Organizer
  第140回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] An optogenetic approach to identify L-DOPA as a neurotransmitter in the nucleus tractus solitarii2019
- Author(s)
  Daiki Masukawa, Yuka Nakao, Hiroki Muneto, Ryang Kim, Haruhiko Bito, Yoshio Goshima
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K14923
[Presentation] GPR143, an L-DOPA receptor, may help control inflammation in adenine-induced chronic kidney disease.2019
- Author(s)
  Hashimoto T, Nakano M, Suzuki S, Yamada T, Masukawa D, Koga M, Ito R, Haruhara K, Wakui H, Tamura K, Goshima Y
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] ドーパ受容体 GPR143 遺伝子欠損マウスにおけるニコチンの効果および喫煙患者における GPR143 の一塩基多型解析2019
- Author(s)
  増川太輝、西澤大輔、笠原由佳、北村慧、金井香央里、池田和隆、五嶋良郎
- Organizer
  第140回薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18K14923
[Presentation] Immunoreactive signals of GPR143 in the tegmental area, substantia nigra and their trajectories.Immunoreactive signals of GPR143 in the tegmental area, substantia nigra and their trajectories.2018
- Author(s)
  Takizawa K, Koga M, Masukawa D, Nakamura F, Goshima Y
- Organizer
  The 18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] ドーパ受容体候補分子の同定とニコチン作用における役割.2018
- Author(s)
  五嶋良郎, 増川太輝, 古賀資和, 橋本達夫, 小倉顕一
- Organizer
  公益財団法人喫煙科学研究財団・第33回平成29年度助成研究発表会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] Tyrosine hydroxylase (TH) and/or rBAT positive neuron in primary afferent innervates in the nucleus tractus solitarii2018
- Author(s)
  Daiki Masukawa, Yuka Nakao, Yoshio Goshima
- Organizer
  18th world congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14923
[Presentation] The role of L-DOPA as a neurotransmitter.2018
- Author(s)
  Goshima Y, Masukawa D, Koga M, Hashimoto T
- Organizer
  The 18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] L-DOPA受容体候補分子GPR143の中脳ドパミン神経核及びその投射野における分布.2018
- Author(s)
  瀧澤光太郎, 古賀資和, 増川太輝, 中村史雄, 五嶋良郎
- Organizer
  第139回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] Tyrosine hydroxylase and/or rBAT positive neuron in primary afferent innervates in the nucleus tractus solitarii.2018
- Author(s)
  Masukawa D, Nakao Y, Goshima Y
- Organizer
  The 18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] L-DOPA cyclohexyl ester, an L-DOPA antagonist, protects neurostimmulated contractile response in mice heart.2018
- Author(s)
  Hashimoto T, Hamaguchi S, Masukawa D, Koga M, Nakano M, Tanaka H, Tamura K, Goshima Y
- Organizer
  The 18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] L-DOPA CHE, an L-DOPA antagonist, protects neurostimulated contractile response in mice heart2018
- Author(s)
  Tatsuo Hashimoto, Shogo Hamaguchi, Daiki Masukawa, Motokazu Koga, Nakano Masayuki, Hikaru Tanaka, Koichi Tamura, Yoshio Goshima
- Organizer
  第18回国際薬理学・臨床薬理学会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06896
[Presentation] An optogenetic approach to identify L-DOPA as a neurotransmitter in the nucleus tractus solitarii2018
- Author(s)
  Daiki Masukawa, Yuka Nakao, Hiroki Muneto, Ryang Kim, Haruhiko Bito, Yoshio Goshima
- Organizer
  第92回薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K14923
[Presentation] The localization and innervation of rBAT and tyrosine hydroxylase positive neuron in the nucleus tractus solitarii.2018
- Author(s)
  Masukawa D, Nakao Y, Goshima Y
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] 延髄孤束核におけるL-DOPA神経伝達機構の解明.2018
- Author(s)
  増川太輝, 中尾友香, 宗藤大樹，金亮，尾藤晴彦，五嶋良郎
- Organizer
  第139回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-18H02580
[Presentation] The localization and innervation of rBAT and tyrosine hydroxylase positive neuron2018
- Author(s)
  Daiki Masukawa, Yuka Nakao, Yoshio Goshima
- Organizer
  第41回神経科学大会
- Data Source
  KAKENHI-PROJECT-18K14923
[Presentation] Screening for L-DOPA ligands by monitoring central cardiovascular regulation in the nucleus tractus solitarii.2017
- Author(s)
  Nakao Y, Masukawa D, Koga M, Goshima Y
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] DOPA-GPR143 signal augments α1-adrenergic receptor response2017
- Author(s)
  増川太輝、中村史雄、横山詩子、古賀資和、石川義弘、五嶋良郎
- Organizer
  第 90 回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-15K21273
[Presentation] DOPA-GPR143 signal augments α1-adrenergic receptor response2017
- Author(s)
  Masukawa D, Nakamura F, Yokoyama U, Koga M, Ishikawa Y, Goshima Y
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] GPR143 is involved in dopamine D2 receptor-mediated transmission in mice2017
- Author(s)
  Kitamura S, Masukawa D, Koga M, Nakamura F, Goshima Y
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] Immunoreactive signals of GPR 143 in ventral tegmental areas and its trajectory.2017
- Author(s)
  Koga M, Masukawa D, Nakamura F, Goshima Y
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] L-DOPA受容体候補分子GPR143のマウス腹側被蓋野及びその投射野における分布.2017
- Author(s)
  瀧澤光太郎, 古賀資和, 増川太輝, 中村史雄, 五嶋良郎
- Organizer
  第137回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] ドーパ受容体GPR143とアドレナリンα1受容体との機能的連関と複合体形成.2017
- Author(s)
  増川太輝, 古賀資和, 涌井広道, 上窪裕二, 横山詩子, 中村史雄, 櫻井隆, 田村功一, 石川義弘, 五嶋良郎
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] GPR143遺伝子欠損マウスにおけるメチルフェニデート, コカイン及びニコチンの行動に及ぼす効果.2017
- Author(s)
  金井香央里, 増川太輝, 古賀資和, 北村慧, 角田貴大, 五嶋良郎
- Organizer
  第137回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] L-DOPAの肺高血圧モデル肺血管におけるフェニレフリン応答の修飾作用2017
- Author(s)
  古賀資和, 増川太輝, 中村史雄, 菅原陽, 水野祐介, 後藤隆久, 五嶋良郎
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] ドーパ受容体 GPR143 とアドレナリン α1 受容体との機能的連関と複合体形成2017
- Author(s)
  増川太輝、古賀資和、涌井広道、上窪裕二、横山詩子、中村史雄、櫻井隆、田村功一、石川義弘、五嶋良郎
- Organizer
  第 136 回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K21273
[Presentation] L- DOPA sensitizes nervous system by modulating the vascular α1-adrenergic receptor.2017
- Author(s)
  Masukawa D, Koga M, Wakui H, Kamikubo Y, Yokoyama U, Nakamura F, Tamura K, Umemura S, Sakurai T, Ishikawa Y, Goshima Y
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] ドーパ-GPR143シグナルはアドレナリンα1受容体応答を増強する2017
- Author(s)
  増川太輝、中村史雄、横山詩子、上窪裕二、古賀資和、石川義弘、櫻井隆、五嶋良郎
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎新聞文化ホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K21273
[Presentation] ドーパ受容体GPR143はアドレナリンα1受容体応答を増強する.2016
- Author(s)
  増川太輝、古賀資和、横山詩子、上窪裕二、中村史雄、櫻井隆、石川義弘、五嶋良郎
- Organizer
  第135回日本薬理学会関東部会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] Functional coupling between GPR143, a DOPA receptor, and alpha1-adrenergic receptor regulates peripheral sympathetic nerve transmission.2016
- Author(s)
  Daiki Masukawa, Anna Sezaki, Fumio Nakamura, Motokazu Koga, Yoshio Goshima
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] The effect of dopamine receptors agonists in gpr143-/y mice.2016
- Author(s)
  Satoshi Kitamura, Daiki Masukawa, Motokazu Koga, Fumio Nakamura, Yoshio Goshima
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] 中枢神経系における抗ドーパ抗体を用いた免疫組織化学的検討.2016
- Author(s)
  増川太輝、ジョンソン実歌、古賀資和、中村史雄、五嶋良郎
- Organizer
  第135回日本薬理学会関東部会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] General behavioral test in the gpr143-/y mice.2016
- Author(s)
  Hiromi Okatsu, Junka Koyama, Haruko Nakamura, Daiki Masukawa, Motokazu Koga, Fumio Nakamura, Tohru Kimura, Yoshio Goshima
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] Distribution of GPR143-immunoreactive cells in the mouse ventral tegmental area.2016
- Author(s)
  Motokazu Koga, Daiki Masukawa, Fumio Nakamura, Yoshio Goshima
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] DOPA-GPR143 signal augments pressor response mediated by a1-adrenergic receptor.2016
- Author(s)
  Daiki Masukawa, Fumio Nakamura, Utako Yokoyama, Motokazu Koga, Yoshihiro Ishikawa, Yoshio Goshima
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] ドーパ受容体 GPR143 はアドレナリン α1 受容体応答を増強する2016
- Author(s)
  増川太輝、古賀資和、横山詩子、上窪裕二、中村史雄、櫻井隆、石川義弘、五嶋良郎
- Organizer
  第135回薬理学会関東部会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Data Source
  KAKENHI-PROJECT-15K21273
[Presentation] GPR143遺伝子欠損マウスにおけるドパミン受容体作動薬の効果2015
- Author(s)
  北村慧、増川太輝、古賀資和、中村史雄、五嶋良郎
- Organizer
  第133回日本薬理学会関東部会
- Place of Presentation
  柏の葉カンファレンスセンター（千葉県柏市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] Distribution and function of L-DOPA receptor, ocular albinism 1(OA-1), in the central nervous system.2015
- Author(s)
  Daiki Masukawa, Fumio Nakamura, Yoshio Goshima
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場、神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15H04687
[Presentation] L-DOPAによって誘発される行動薬理学的変化の解析2015
- Author(s)
  上田傑、増川太輝、古賀資和、中村史雄、五嶋良郎
- Organizer
  第132回日本薬理学会関東部会
- Place of Presentation
  明海大学浦安キャンパス（千葉県浦安市）
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15H04687

1. GOSHIMA Yoshio (00153750)

# of Collaborated Projects: 3 results

# of Collaborated Products: 57 results
2. 古賀資和 (00637233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
3. FUKAZAWA Yugo (60343745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ICHINOSE Hiroshi (90192492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Hashimoto Tatsuo (20363806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. 中村史雄 (10262023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
7. 及川雅人 (70273571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田村功一 (40285143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 小池正人 (80347210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 新井信隆 (10167984)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 實木亨 (10546675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 笠原由佳 (50838208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 徳留健 (00443474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NISHIZAWA Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 池田和隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 村田航志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Masukawa Daiki 増川 太輝

MASUKAWA Daiki 増川 太輝

Research Projects

Research Products

Co-Researchers

脳内報酬系・副交感神経系に着目した難治性心疾患およびその合併症の画期的治療法開発Principal Investigator

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The analysis for the circuits of L-DOPA-containing neurons in the central nervous system

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Neural circuits of L-DOPAnergic neurotransmission and their mechanisms of actionPrincipal Investigator

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The functional analysis of L-DOPA neurotransmission in the nucleus tractus solitariiPrincipal Investigator

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Dopa as a neurotransmitter in heart failure and acute kidney injury

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Roles of L-DOPA as a neurotransmitter and L-DOPA reuptake systems involved

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Functional analysis of interaction between DOPA and Glutamate neurotransmission in the nucleus tractus solitariiPrincipal Investigator

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Functional analysis of DOPAergic transmission in cardiovascular system

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[Journal Article] Coupling between GPR143 and dopamine D2 receptor is required for selective potentiation of dopamine D2 receptor function by L-3,4-dihydroxyphenylalanine in the dorsal striatum2023

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[Journal Article] L-DOPA receptor GPR143 functionally couples with adrenergic α1B receptor at the second transmembrane interface2023

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[Journal Article] Involvement of the L-DOPA receptor GPR143 in acute and chronic actions of methylphenidate2023

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[Journal Article] Right ventricular overloading is attenuated in monocrotaline-induced pulmonary hypertension model rats with a disrupted Gpr143 gene, the gene that encodes the 3,4-l-dihydroxyphenyalanine (l-DOPA) receptor.2022

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[Journal Article] L-DOPA-Induced Neurogenesis in the Hippocampus Is Mediated Through GPR143, a Distinct Mechanism of Dopamine.2022

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[Journal Article] Genetic associations of single nucleotide polymorphisms in the L-DOPA receptor (GPR143) gene with severity of nicotine dependence in Japanese individuals, and attenuation of nicotine reinforcement in Gpr143 gene-deficient mice2020

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Masukawa Daiki 増川太輝

MASUKAWA Daiki 増川太輝

[Journal Article] 分子から迫る神経薬理学　ドーパ受容体候補分子からみるドーパ療法の応用および問題点.2018

[Journal Article] 分子から迫る神経薬理学　ドーパ受容体の生理学的および薬理学的作用.2018

[Journal Article] 分子から迫る神経薬理学　ドーパ神経伝達物質仮説：ドーパ受容体は存在するか？2018