Takagi Hideaki 高木秀明

Researcher Number	10719628
Other IDs
Affiliation (Current)	2025: 宮崎大学, 医学部, 客員研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 宮崎大学, 医学部, 客員研究員 2015 – 2021: 宮崎大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 49070:Immunology-related / Immunology
Keywords	Principal Investigator 形質細胞様樹状細胞 / がん免疫抑制機構 / がん微小環境 / がん免疫 / がん免疫応答 / ん免疫応答 / 抗原特異的Foxp3+Treg / 腸管免疫 / アレルギー / 抗原特異的 … More / 制御性T細胞 / 粘膜免疫 / 経口免疫寛容 / I型IFN / Toll様受容体 / 炎症反応 / 自己免疫疾患 / I型インターフェロン Less

Analysis of the mechanism for tumor immune suppression based on the tolerogenesis of plasmacytoid dendritic cellsPrincipal Investigator
- Principal Investigator
  
  Takagi Hideaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of Miyazaki
Critical role of plasmacytoid dendritic cells in induction of oral tolerancePrincipal Investigator
- Principal Investigator
  
  Takagi Hideaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  University of Miyazaki
Analysis on the mechanism of immune regulation by plasmacytoid dendritic cells in the development of autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  Takagi Hideaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  University of Miyazaki

All 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy2020
- Author(s)
  Miyanaga Noriaki、Takagi Hideaki、Uto Tomofumi、Fukaya Tomohiro、Nasu Junta、Fukui Takehito、Nishikawa Yotaro、Sparwasser Tim、Choijookhuu Narantsog、Hishikawa Yoshitaka、Nakamura Takeshi、Tono Tetsuya、Sato Katsuaki
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 1-12
- DOI
  10.1038/s42003-020-01466-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15194, KAKENHI-PROJECT-19K16477
[Journal Article] Pivotal role of CD103 in the development of psoriasiform dermatitis2020
- Author(s)
  Fukui Takehito、Fukaya Tomohiro、Uto Tomofumi、Takagi Hideaki、Nasu Junta、Miyanaga Noriaki、Nishikawa Yotaro、Koseki Haruhiko、Choijookhuu Narantsog、Hishikawa Yoshitaka、Yamashita Yoshihiro、Sato Katsuaki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41598-020-65355-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-18K15194, KAKENHI-PROJECT-19K16477
[Journal Article] Pivotal role of the carbohydrate recognition domain in self-interaction of CLEC4A to elicit the ITIM-mediated inhibitory function in murine conventional dendritic cells in vitro2020
- Author(s)
  Nasu Junta、Uto Tomofumi、Fukaya Tomohiro、Takagi Hideaki、Fukui Takehito、Miyanaga Noriaki、Nishikawa Yotaro、Yamasaki Sho、Yamashita Yoshihiro、Sato Katsuaki
- Journal Title
  
  International Immunology
  
  Volume: 32 Issue: 10 Pages: 673-682
- DOI
  10.1093/intimm/dxaa034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-18K15194
[Journal Article] The HDAC Inhibitor, SAHA, Combined with Cisplatin Synergistically Induces Apoptosis in Alpha-fetoprotein-producing Hepatoid Adenocarcinoma Cells2019
- Author(s)
  Kyaw MTH, Yamaguchi Y, Choijookhuu N, Yano K, Takagi H, Takahashi N, Synn Oo P, Sato K, Hishikawa Y.
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 52 Issue: 1 Pages: 1-8
- DOI
  10.1267/ahc.18044
- NAID
  130007605543
- ISSN
  0044-5991, 1347-5800
- Year and Date
  2019-02-28
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08471, KAKENHI-PROJECT-18K15194
[Journal Article] Pivotal Role of IL-22 Binding Protein in the Epithelial Autoregulation of Interleukin-22 Signaling in the Control of Skin Inflammation2018
- Author(s)
  Tomohiro Fukaya, Takehito Fukui, Tomofumi Uto, Hideaki Takagi, Junta Nasu, Noriaki, Miyanaga, Keiichi Arimura, Takeshi Nakamura, Haruhiko Koseki, Narantsog Choijookhuu, Yoshitaka Hishikawa, Katsuaki Sato
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 1-13
- DOI
  10.3389/fimmu.2018.01418
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15732, KAKENHI-PROJECT-18K15194, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-18H02670, KAKENHI-PROJECT-16K08471
[Journal Article] Selective depletion of basophils ameliorates immunoglobulin E-mediated anaphylaxis2017
- Author(s)
  Nakamura, T., Fukaya, T., Uto, T., Takagi, H., Arimura, K., Tono, T., and Sato, K.
- Journal Title
  
  Biochem. Biophys. Rep.
  
  Volume: 9 Pages: 29-35
- DOI
  10.1016/j.bbrep.2016.11.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860337, KAKENHI-PROJECT-15K19134
[Journal Article] Crucial role of plasmacytoid dendritic cells in the development of acute colitis through the regulation of intestinal inflammation2017
- Author(s)
  Arimura, K., Takagi, H., Uto, T., Fukaya, T., Nakamura, T.,Choijookhuu, N., Hishikawa,Y. Yamashita,Y., and Sato, K.
- Journal Title
  
  Mucosal Immunol.
  
  Volume: 印刷中 Issue: 4 Pages: 957-970
- DOI
  10.1038/mi.2016.96
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860337, KAKENHI-PROJECT-15K19134
[Journal Article] Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation2016
- Author(s)
  Hideaki Takagi, Keiichi Arimura, Tomofumi Uto, Tomohiro Fukaya, Takeshi Nakamura, Narantsog Choijookhuu, Yoshitaka Hishikawa, Katsuaki Sato
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 24477-24477
- DOI
  10.1038/srep24477
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19134, KAKENHI-PROJECT-26860337, KAKENHI-PROJECT-16K08471
[Presentation] Plasmacytoid dendritic cells potentiate an effective anti-tumor immunity by preventing T-cell exhaustion2021
- Author(s)
  高木秀明
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07245
[Presentation] Essential role of submandibular lymph node conventional dendritic cells in the protective effect of sublingual immunotherapy on allergic asthma2019
- Author(s)
  高木秀明、宮永宜明、宇都倫史、深谷知宏、奈須遵太、福井丈仁、西川陽太郎、佐藤克明
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15194
[Presentation] Crucial role of conventional dendritic cells in the protective effect of sublingual immunotherapy (SLIT) on allergic disorders.2018
- Author(s)
  高木秀明、宮永宣明、宇都倫史、深谷知宏、奈須遵太、福井丈仁、佐藤克明
- Organizer
  第46回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K15194
[Presentation] Tolerogenesis of gastrointestinal plasmacytoid dendritic cells impacts the induction of oral tolerance2017
- Author(s)
  高木秀明、宇都倫史、深谷知宏、奈須遵太、福井丈仁、宮永宜明、有村慶一、中村雄、佐藤克明
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K19134
[Presentation] Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation2016
- Author(s)
  高木秀明、有村慶一、宇都倫史、深谷知宏、中村雄、佐藤克明
- Organizer
  第45回日本免疫学会総会
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19134
[Presentation] Critical role of plasmacytoid dendritic cells in the initiation of toll-like receptor 7-mediated autoimmune inflammation2015
- Author(s)
  高木秀明、有村慶一、宇都倫史、深谷知宏、中村雄、佐藤克明
- Organizer
  日本免疫学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19134

1. 深谷知宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 古関明彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 山崎晶

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takagi Hideaki 高木 秀明

Research Projects

Research Products

Co-Researchers

Analysis of the mechanism for tumor immune suppression based on the tolerogenesis of plasmacytoid dendritic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Critical role of plasmacytoid dendritic cells in induction of oral tolerancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis on the mechanism of immune regulation by plasmacytoid dendritic cells in the development of autoimmune diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pivotal role of CD103 in the development of psoriasiform dermatitis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pivotal role of the carbohydrate recognition domain in self-interaction of CLEC4A to elicit the ITIM-mediated inhibitory function in murine conventional dendritic cells in vitro2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The HDAC Inhibitor, SAHA, Combined with Cisplatin Synergistically Induces Apoptosis in Alpha-fetoprotein-producing Hepatoid Adenocarcinoma Cells2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Pivotal Role of IL-22 Binding Protein in the Epithelial Autoregulation of Interleukin-22 Signaling in the Control of Skin Inflammation2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Selective depletion of basophils ameliorates immunoglobulin E-mediated anaphylaxis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crucial role of plasmacytoid dendritic cells in the development of acute colitis through the regulation of intestinal inflammation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Plasmacytoid dendritic cells potentiate an effective anti-tumor immunity by preventing T-cell exhaustion2021

Author(s)

Organizer

Data Source

[Presentation] Essential role of submandibular lymph node conventional dendritic cells in the protective effect of sublingual immunotherapy on allergic asthma2019

Author(s)

Organizer

Data Source

[Presentation] Crucial role of conventional dendritic cells in the protective effect of sublingual immunotherapy (SLIT) on allergic disorders.2018

Author(s)

Organizer

Data Source

[Presentation] Tolerogenesis of gastrointestinal plasmacytoid dendritic cells impacts the induction of oral tolerance2017

Author(s)

Takagi Hideaki 高木秀明