MATSUDA Yudai 松田侑大

Researcher Number	10720766
Other IDs	https://orcid.org/0000-0001-5650-4732
Affiliation (based on the past Project Information) *help	2017: 東京大学, 大学院薬学系研究科(薬学部), 特任助教 2015: 東京大学, 大学院薬学系研究科(薬学部), 特任助教 2014 – 2015: 東京大学, 薬学研究科(研究院), 助教 2014: 東京大学, 大学院薬学系研究科, 助教
Review Section/Research Field	Principal Investigator Biomolecular chemistry Except Principal Investigator Biomolecular chemistry / Living organism molecular science / Science and Engineering
Keywords	Principal Investigator 生合成 / 天然物化学 Except Principal Investigator 生合成 / 物質生産 / 遺伝子 / 酵素 / 二次代謝酵素 / 機能制御 / 反応機構 / 構造生物学 … More / 合成生物学 / 酵素工学 / 生合成工学 / 生合成クラスター / 多様性創出 / 遺伝子クラスター / メロテルペノイド Less

糸状菌由来天然物の生合成再構成による新規有用物質の創出Principal Investigator
- Principal Investigator
  
  松田侑大
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Biosynthetic studies on complex natural products
- Principal Investigator
  
  Abe Ikuro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Enzyme engineering for natural product biosynthesis
- Principal Investigator
  
  ABE IKURO
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  The University of Tokyo
Studies on biosynthetic assembly line of meroterpenoids
- Principal Investigator
  
  ABE IKURO
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo

All 2018 2017 2016 2015 2014 2013 2012

All Journal Article Book

[Book] Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites (分担執筆)2014
- Author(s)
  Abe, I., Matsuda, Y.
- Total Pages
  300
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23241068
[Book] Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites (分担執筆)2014
- Author(s)
  Abe, I., Matsuda, Y.
- Total Pages
  300
- Publisher
  Springer
- Data Source
  KAKENHI-PLANNED-22108004
[Journal Article] Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways2018
- Author(s)
  Nakamura Hitomi、Matsuda Yudai、Abe Ikuro
- Journal Title
  
  Nat Prod Rep
  
  Volume: 35 Issue: 7 Pages: 633-645
- DOI
  10.1039/c7np00055c
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836
[Journal Article] Molecular basis for the unusual ring reconstruction in fungal meroterpenoid biogenesis2017
- Author(s)
  Mori Takahiro、Iwabuchi Taiki、Hoshino Shotaro、Wang Hang、Matsuda Yudai、Abe Ikuro
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 13 Issue: 10 Pages: 1066-1073
- DOI
  10.1038/nchembio.2443
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-16J01117
[Journal Article] Astellifadiene, a unique tetracyclic fungal sesterterpene: structure determination by an NMR-coupled crystalline sponge method and elucidation of its biosynthesis2016
- Author(s)
  Matsuda, Y., Mitsuhashi,T., Lee, S., Hoshino, M., Mori, T., Okada, M., Zhang, H., Hayashi, F., Fujita, M., Abe, I.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 55 Issue: 19 Pages: 5785-5788
- DOI
  10.1002/anie.201601448
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-24688011
[Journal Article] An unusual chimeric diterpene synthase from Emericella varicolor and its functional conversion into a sesterterpene synthase by domain swapping2016
- Author(s)
  B. Qin, Y. Matsuda, T. Mori, M. Okada, Z. Quan, T. Mitsuhashi, T. Wakimoto, I. Abe
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 55 Issue: 5 Pages: 1658-1661
- DOI
  10.1002/anie.201509263
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K12740, KAKENHI-PROJECT-15H03112, KAKENHI-PLANNED-16H06443, KAKENHI-PLANNED-16H06448, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-24688011
[Journal Article] Calyculin: Nature’s way of making the sponge-derived cytotoxin2016
- Author(s)
  T. Wakimoto, Y. Egami, I. Abe
- Journal Title
  
  Nat. Prod. Rep.
  
  Volume: 未定 Issue: 6 Pages: 751-760
- DOI
  10.1039/c5np00123d
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K12740, KAKENHI-PROJECT-15H03112, KAKENHI-PROJECT-15H05996, KAKENHI-PLANNED-16H06443, KAKENHI-PLANNED-16H06448, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-26303005
[Journal Article] Discovery of key dioxygenases that diverged the paraherquonin and acetoxydehydroaustin pathways in Penicillium brasilianum2016
- Author(s)
  Matsuda, Y., Iwabuchi,T., Fujimoto, T., Awakawa,T., Nakashima, Y., Mori, T., Zhang, H., Hayashi, F., Abe, I.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 138 Issue: 38 Pages: 12671-12677
- DOI
  10.1021/jacs.6b08424
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-15J12340
[Journal Article] Unusual chemistries in fungal meroterpenoid biosynthesis2016
- Author(s)
  Matsuda, Y., Awakawa, T., Mori, T., Abe, I.
- Journal Title
  
  Curr. Opin. Chem. Biol.
  
  Volume: 31 Pages: 1-7
- DOI
  10.1016/j.cbpa.2015.11.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836
[Journal Article] Genome-based discovery of an unprecedented cyclization mode in fungal sesterterpenoids biosynthesis2016
- Author(s)
  Okada, M., Matsuda, Y., Mitsuhashi, T., Hoshino, S., Mori, T., Nakagawa, K., Quan, Z., Qin, B., Zhang, H., Hayashi, F., Kawaide, H., Abe, I.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 138 Issue: 31 Pages: 10011-10018
- DOI
  10.1021/jacs.6b05799
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-15H01836, KAKENHI-PROJECT-16J01117, KAKENHI-PROJECT-24688011
[Journal Article] Uncovering the unusual D-ring construction in terretonin biosynthesis by collaboration of a multifunctional cytochrome P450 and a unique isomerase2015
- Author(s)
  Matsuda, Y., Iwabuchi, T., Wakimoto, T., Awakawa, T., Abe, I.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 137 Issue: 9 Pages: 3393-3401
- DOI
  10.1021/jacs.5b00570
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068, KAKENHI-PROJECT-26560428, KAKENHI-PROJECT-15K12740, KAKENHI-PROJECT-15H03112, KAKENHI-PROJECT-15H01836
[Journal Article] Molecular basis for stellatic acid biosynthesis: a genome mining approach for discovery of sesterterpene synthases2015
- Author(s)
  Matsuda, Y., Mitsuhashi, T., Quan, Z., Abe, I.
- Journal Title
  
  Org. Lett.
  
  Volume: 17 Issue: 18 Pages: 4644-4647
- DOI
  10.1021/acs.orglett.5b02404
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H01836
[Journal Article] Complete biosynthetic pathway of anditomin: nature's sophisticated synthetic route to a complex fungal meroterpenoid2014
- Author(s)
  Matsuda, Y., Wakimoto, T., Mori, T., Awakawa, T., Abe, I.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 Issue: 43 Pages: 15326-15336
- DOI
  10.1021/ja508127q
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068, KAKENHI-PUBLICLY-25108705, KAKENHI-PROJECT-25560399, KAKENHI-PROJECT-26560428
[Journal Article] Spiro-ring formation is catalyzed by a multifunctional dioxygenase in austinol biosynthesis2013
- Author(s)
  Y. Matsuda, T. Awakawa, T. Wakimoto, and I. Abe
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 30 Pages: 10962-10965
- DOI
  10.1021/ja405518u
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22108001, KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068, KAKENHI-PUBLICLY-25108705, KAKENHI-PROJECT-25560399
[Journal Article] Reconstituted biosynthesis of fungal meroterpenoid andrastin A2013
- Author(s)
  Matsuda, Y., Awakawa, T., Abe, I.
- Journal Title
  
  Tetrahedron
  
  Volume: 69 Issue: 38 Pages: 8199-8204
- DOI
  10.1016/j.tet.2013.07.029
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22108004, KAKENHI-PROJECT-23241068
[Journal Article] Terretonin biosynthesis requires methylation as essential step for cyclization.2012
- Author(s)
  Y. Matsuda, T. Awakawa, T. Itoh, T. Wakimoto, T. Kushiro, I. Fujii, Y. Ebizuka, I. Abe
- Journal Title
  
  ChemBioChem
  
  Volume: 13(12) Issue: 12 Pages: 1738-1741
- DOI
  10.1002/cbic.201200369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241054, KAKENHI-PROJECT-23241068, KAKENHI-PLANNED-22108004, KAKENHI-PUBLICLY-23108524

1. ABE IKURO (40305496)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. AWAKAWA Takayoshi (80609834)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. MORITA Hiroyuki (20416663)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. WAKIMOTO Toshiyuki (70363900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. SUGIO Shigetoshi (10537343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NOGUCHI Hiroshi (60126141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KUSHIRO Testuo (80373299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. SENDA Toshiya (30272868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中村仁美 (90800657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 岡田正弘 (40377792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 森貴裕 (60734564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 江上蓉子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUDA Yudai 松田 侑大

Research Projects

Research Products

Co-Researchers

糸状菌由来天然物の生合成再構成による新規有用物質の創出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biosynthetic studies on complex natural products

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Enzyme engineering for natural product biosynthesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on biosynthetic assembly line of meroterpenoids

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites (分担執筆)2014

Author(s)

Total Pages

Publisher

Data Source

[Book] Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites (分担執筆)2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular basis for the unusual ring reconstruction in fungal meroterpenoid biogenesis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Astellifadiene, a unique tetracyclic fungal sesterterpene: structure determination by an NMR-coupled crystalline sponge method and elucidation of its biosynthesis2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An unusual chimeric diterpene synthase from Emericella varicolor and its functional conversion into a sesterterpene synthase by domain swapping2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Calyculin: Nature’s way of making the sponge-derived cytotoxin2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Discovery of key dioxygenases that diverged the paraherquonin and acetoxydehydroaustin pathways in Penicillium brasilianum2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unusual chemistries in fungal meroterpenoid biosynthesis2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genome-based discovery of an unprecedented cyclization mode in fungal sesterterpenoids biosynthesis2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Uncovering the unusual D-ring construction in terretonin biosynthesis by collaboration of a multifunctional cytochrome P450 and a unique isomerase2015

Author(s)

MATSUDA Yudai 松田侑大