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Masuda Hiroki  枡田 大生

ORCIDConnect your ORCID iD *help
Researcher Number 10722936
Other IDs
Affiliation (Current) 2025: 千葉大学, 大学院医学研究院, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 千葉大学, 大学院医学研究院, 助教
2019: 千葉大学, 医学部附属病院, 助教
2017 – 2018: 千葉大学, 医学部附属病院, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 52020:Neurology-related / Neurology
Except Principal Investigator
Basic Section 47060:Clinical pharmacy-related
Keywords
Principal Investigator
多発性硬化症 / 血液脳関門 / miRNA / 実験的アレルギー性脳脊髄炎 / 神経免疫学 / 神経科学 / ミトコンドリア / 脳神経疾患 / 可溶型CD40リガンド
Except Principal Investigator
Drug screening … More / In vitro model / 中枢神経系疾患 / in vitro / 生体模倣システム / 血液脳関門 Less
  • Research Projects

    (5 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (7 People)
  •  miR-145を標的とした血液脳関門破綻防止による多発性硬化症の革新的治療法開発Principal Investigator

    • Principal Investigator
      枡田 大生
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Chiba University
  •  ヒト脳マイクロパソフィジオロジカルシステムズ:脳疾患の生体模倣と創薬研究への応用

    • Principal Investigator
      降幡 知巳
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Develpment of the biomarker for the blood-brain barrier breakdown in multiple sclerosis by exosomal miRNA.Principal Investigator

    • Principal Investigator
      Masuda Hiroki
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Chiba University
  •  Development of innovative treatment targeted for CD40 ligand for patients with multiple sclerosisPrincipal Investigator

    • Principal Investigator
      Masuda Hiroki
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Chiba University
  •  Developement of the innovative imaging of the blood brain barrierPrincipal Investigator

    • Principal Investigator
      Masuda Hiroki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research)
    • Research Field
      Neurology
    • Research Institution
      Chiba University

All 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Soluble CD40 ligand disrupts the blood?brain barrier and exacerbates inflammation in experimental autoimmune encephalomyelitis2018

    • Author(s)
      Masuda Hiroki、Mori Masahiro、Umehara Kenta、Furihata Tomomi、Uchida Tomohiko、Uzawa Akiyuki、Kuwabara Satoshi
    • Journal Title

      J Neuroimmunol

      Volume: 316 Pages: 117-120

    • DOI

      10.1016/j.jneuroim.2018.01.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09691, KAKENHI-PROJECT-17K16109
  • [Journal Article] Soluble CD40 ligand contributes to blood brain barrier breakdown and central nervous system inflammation in multiple sclerosis and neuromyelitis optica spectrum disorder2017

    • Author(s)
      Masuda H, Mori M, Uchida T, Uzawa A, Ohtani R, Kuwabara S.
    • Journal Title

      J Neuroimmnol

      Volume: 305 Pages: 102-107

    • DOI

      10.1016/j.jneuroim.2017.01.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09691, KAKENHI-PROJECT-17K16109
  • [Presentation] Severe, transient neurological deficits associated with breakdown of the blood-brain barrier2019

    • Author(s)
      G. Delattre, H. Masuda, K.J. Smith
    • Organizer
      ECTRIMS 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KK0187
  • [Presentation] Soluble CD40 ligand contributes to blood-brain barrier breakdown in patients with multiple sclerosis and mice with experimental autoimmune encephalomyelitis2018

    • Author(s)
      Hiroki Masuda, Masahiro Mori, Tomohiko Uchida, Akiyuki Uzawa, Ryohei Ohtani, and Satoshi Kuwabara
    • Organizer
      ECTRIMS2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16109
  • [Presentation] Soluble CD40 ligand contributes to blood–brain barrier breakdown and central nervous system inflammation2017

    • Author(s)
      Hiroki Masuda, Masahiro Mori, Tomohiko Uchida, Akiyuki Uzawa, Ryohei Otani, Satoshi Kuwabara
    • Organizer
      Sendai Conference 2017
    • Data Source
      KAKENHI-PROJECT-17K16109
  • [Presentation] Soluble CD40 ligand contributes to blood–brain barrier breakdown and central nervous system inflammation2017

    • Author(s)
      Hiroki Masuda; Masahiro Mori; Tomohiko Uchida; Akiyuki Uzawa; Ryohei Ohtani; and Satoshi Kuwabara
    • Organizer
      XXIII World Congress of Neurology
    • Data Source
      KAKENHI-PROJECT-17K16109
  • [Presentation] 可溶性CD40リガンドは血液脳関門破綻を介して中枢神経の炎症に寄与する2017

    • Author(s)
      枡田大生、森 雅裕、鵜沢顕之、内田智彦、大谷龍平、桑原 聡
    • Organizer
      第29回日本神経免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K16109
  • 1.  降幡 知巳 (80401008)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  高山 祐三 (60608438)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  森尾 花恵 (70908524)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  小島 伸彦 (90342956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MASAHIRO Mori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 6.  SATOSHI Kuwabara
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  UZAWA Akiyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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