Nagai Tomoaki 永井友朗

Researcher Number	10723059
Other IDs	https://orcid.org/0000-0002-9577-9314
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 福島県立医科大学, 医学部, 助教 2014 – 2017: 東北大学, 生命科学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Functional biochemistry / Cell biology
Keywords	Principal Investigator マイクロパターニング / 集団移動 / 中心体 / 一次繊毛 / EMT / 上皮細胞 / IFT / ヘッジホッグ経路 / 一次繊毛先端 / 細胞のパターニング培養 … More / 上皮極性 / 間葉系幹細胞 / CEP104 / 一次繊毛形成 / 細胞情報伝達機構 / 細胞周期 / TTBK2キナーゼ / 脊髄小脳変性症 / 母中心小体 / Cep164 / TTBK2 / 紡錘体微小管 / CCT複合体 / 分裂期紡錘体形成 / 劣性遺伝性精神遅滞 / 体細胞分裂 / 微小管 / Furry / 分裂期紡錘体 Less

Mechanisms how to establish collective migration by organizing single-cell motility in epithelial cells and those undergoing epithelial-to-mesenchymal transitionPrincipal Investigator
- Principal Investigator
  
  永井友朗
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Fukushima Medical University
一次繊毛先端部におけるアンテナ機能制御と繊毛病発症の分子機構Principal Investigator
- Principal Investigator
  
  永井友朗
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Fukushima Medical University
Mechanisms of growth arrest-induced TTBK2 activation and its role for ciliogenesisPrincipal Investigator
- Principal Investigator
  
  Nagai Tomoaki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku University
Functional analysis of microtubule-binding protein, Furry, in the formation of mitotic spindle and recessive mental retardationPrincipal Investigator
- Principal Investigator
  
  Nagai Tomoaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University

All 2024 2022 2017 2015 2014 Other

All Journal Article Presentation Book

[Book] 哺乳類NDRキナーゼの細胞機能-もう一つのHippo下流キナーゼ2014
- Author(s)
  永井友朗、水野健作
- Total Pages
  6
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-26840060
[Journal Article] miR-200c-141 induces a hybrid E/M state and promotes collective cell migration in MDA-MB-231 cells2024
- Author(s)
  Nagai Tomoaki、Sato Misa、Nishita Michiru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 709 Pages: 149829-149829
- DOI
  10.1016/j.bbrc.2024.149829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06084, KAKENHI-PROJECT-23K06678
[Journal Article] Jasplakinolide induces primary cilium formation through cell rounding and YAP inactivation2017
- Author(s)
  Nagai, T.、and Mizuno, K.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 8 Pages: e0183030-e0183030
- DOI
  10.1371/journal.pone.0183030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04347, KAKENHI-PROJECT-16K20910
[Presentation] Slug依存的な上皮間葉転換の誘導が集団的細胞運動に与える影響2022
- Author(s)
  永井友朗、桃北恵輔、梶弘和、西田満
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06084
[Presentation] TGF-β刺激依存的な集団移動におけるROCK阻害剤Y-27632の影響2022
- Author(s)
  前田紗希、永井友朗、梶弘和、西田満
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06084
[Presentation] Cep164による一次繊毛形成キナーゼTTBK2の活性化機構2017
- Author(s)
  永井友朗、藤井崇平、水野健作
- Organizer
  第69回細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-16K20910
[Presentation] FurryはYAPのリン酸化と局在を制御する2015
- Author(s)
  入江和樹、Alfredo Mateo Torres、永井友朗、水野健作
- Organizer
  第38回日本分子生物学会・第88会日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26840060
[Presentation] Functional roles of Furry, a casual protein of neurological disorders, in microtubules
- Author(s)
  K. Irie, T. Nagai, K. Mizuno
- Organizer
  The 2nd Taiwan-Tohoku University Neuroscicence Workshop for Young Scientists
- Place of Presentation
  Sendai, Japan
- Year and Date
  2014-11-30 – 2014-12-04
- Data Source
  KAKENHI-PROJECT-26840060

1. 水野健作

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagai Tomoaki 永井 友朗

Research Projects

Research Products

Co-Researchers

Mechanisms how to establish collective migration by organizing single-cell motility in epithelial cells and those undergoing epithelial-to-mesenchymal transitionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

一次繊毛先端部におけるアンテナ機能制御と繊毛病発症の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of growth arrest-induced TTBK2 activation and its role for ciliogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of microtubule-binding protein, Furry, in the formation of mitotic spindle and recessive mental retardationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 哺乳類NDRキナーゼの細胞機能-もう一つのHippo下流キナーゼ2014

Author(s)

Total Pages

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[Journal Article] miR-200c-141 induces a hybrid E/M state and promotes collective cell migration in MDA-MB-231 cells2024

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Journal Title

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[Journal Article] Jasplakinolide induces primary cilium formation through cell rounding and YAP inactivation2017

Author(s)

Journal Title

DOI

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[Presentation] Slug依存的な上皮間葉転換の誘導が集団的細胞運動に与える影響2022

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Organizer

Data Source

[Presentation] TGF-β刺激依存的な集団移動におけるROCK阻害剤Y-27632の影響2022

Author(s)

Organizer

Data Source

[Presentation] Cep164による一次繊毛形成キナーゼTTBK2の活性化機構2017

Author(s)

Organizer

Data Source

[Presentation] FurryはYAPのリン酸化と局在を制御する2015

Author(s)

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Place of Presentation

Year and Date

Data Source

[Presentation] Functional roles of Furry, a casual protein of neurological disorders, in microtubules

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Nagai Tomoaki 永井友朗