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Tokuzen Norihiko  徳善 紀彦

ORCIDConnect your ORCID iD *help
Researcher Number 10723843
Other IDs
Affiliation (based on the past Project Information) *help 2016 – 2022: 愛媛大学, 医学部附属病院, 助教
2015: 愛媛大学, 医学部附属病院, その他
2014 – 2015: 愛媛大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Surgical dentistry / Basic Section 57060:Surgical dentistry-related
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related
Keywords
Principal Investigator
口腔扁平上皮癌 / microRNA / 転移 / 転移関連遺伝子 / 口腔癌 / リンパ節転移 / バイオマーカー / Exosome / 口腔扁平上皮癌患 / 治療標的 / 治療標的分子 / 予後 / CDCA5 … More
Except Principal Investigator
… More 再発監視 / リキッドバイオプシー / 核酸創薬 / リンパ節転移予測 / 転移予測 / エピゲノム異常 / ゲノム異常 / リッキドバイオプシー / 頸部リンパ節転移予測 / 遺伝子異常 / 口腔扁平上皮癌 Less
  • Research Projects

    (4 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (5 People)
  •  Treatment strategies for oral squamous cell carcinoma based on genetic alterlations

    • Principal Investigator
      Nakashiro Koichi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Ehime University
  •  Metastasis-related microRNAs in oral squamous cell carcinomaPrincipal Investigator

    • Principal Investigator
      TOKUZEN NORIHIKO
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Ehime University
  •  Expression and function of serum Exosoomal miRNA in oral squamous cell carcinomaPrincipal Investigator

    • Principal Investigator
      TOKUZEN NORIHIKO
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Ehime University
  •  Expression and function of CDCA5 in OSCCPrincipal Investigator

    • Principal Investigator
      Tokuzen Norihiko
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Ehime University

All 2022 2021 2020 2019 2016 2015 2014

All Journal Article Presentation

  • [Journal Article] Human papillomavirus?16 infection and p16 expression in oral squamous cell carcinoma2021

    • Author(s)
      Tokuzen Norihiko、Nakashiro Koh-ichi、Tojo Shin、Goda Hiroyuki、Kuribayashi Nobuyuki、Uchida Daisuke
    • Journal Title

      Oncology Letters

      Volume: 22 Issue: 1 Pages: 528-528

    • DOI

      10.3892/ol.2021.12789

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03890, KAKENHI-PROJECT-21K10044
  • [Journal Article] MicroRNA-361-3p is a potent therapeutic target for oral squamous cell carcinoma.2020

    • Author(s)
      Ogawa H, Nakashiro KI, Tokuzen N, Kuribayashi N, Goda H, Uchida D.
    • Journal Title

      Cancer Sci.

      Volume: - Issue: 5 Pages: 1645-1651

    • DOI

      10.1111/cas.14359

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11886, KAKENHI-PROJECT-20H03890
  • [Journal Article] Therapeutic potential of targeting cell division cycle associated 5 for oral squamous cell carcinoma2016

    • Author(s)
      Tokuzen N, Nakashiro K, Tanaka H, Iwamoto K, Hamakawa H
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 3 Pages: 2343-53

    • DOI

      10.18632/oncotarget.6148

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15742, KAKENHI-PROJECT-26861727
  • [Presentation] 口腔扁平上皮癌における microRNA-375 の機能と臨床応用2022

    • Author(s)
      雑賀将斗、中城公一、徳善紀彦、内田大亮
    • Organizer
      第46回日本頭頸部癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] Clinical significance of CXCL13 as a novel biomarker in advance oral squamous cell carcinoma2022

    • Author(s)
      Tojo S, Kuribayashi N, Nakashiro K, Tokuzen N, Goda H, Kojima S, Uchida D
    • Organizer
      The 81th Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] 口腔扁平上皮癌の遺伝子異常とその臨床的意義2022

    • Author(s)
      中城公一、徳善紀彦、栗林伸行、合田啓之、内田大亮
    • Organizer
      第67回日本口腔外科学会総会・学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] Expression and function of microRNA-375 in human oral squamous cell carcinoma2022

    • Author(s)
      Saika M, Nakashiro K, Tokuzen N, Shirai H, Uchida D
    • Organizer
      The 81th Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] ヒト口腔扁平上皮癌における頸部リンパ節転移予測マーカーの探索2022

    • Author(s)
      雑賀将斗、中城公一、徳善紀彦、栗林伸行、白井博之、内田大亮
    • Organizer
      第58回日本口腔組織培養学会学術大会・総会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] 口腔扁平上皮癌治療標的としての miR-346 の有用性2022

    • Author(s)
      白井博之、中城公一、徳善紀彦、雑賀将斗、内田大亮
    • Organizer
      第26回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] 口腔扁平上皮癌転移リンパ節の網羅的遺伝子発現解析2022

    • Author(s)
      徳善紀彦、中城公一、栗林伸行、合田啓之、内田大亮
    • Organizer
      第67回日本口腔外科学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] Downregulation of microRNA-375 is associated with lymph node metastasis in oral squamous cell carcinoma2021

    • Author(s)
      Masato Saika, Koh-ichi Nakashiro, Norihiko Tokuzen, Nobuyuki Kuribayashi, Hiroyuki Goda, Daisuke Uchida
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] 唾液腺癌遠隔転移症例に対するがんゲノム医療の試み2021

    • Author(s)
      徳善紀彦,中城公一,合田啓之,内田大亮
    • Organizer
      第25回日本がん分子標的治療学会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] 口腔扁平上皮癌における p53 遺伝子の変異解析2021

    • Author(s)
      児島さやか, 栗林 伸行, 中城 公一, 東條 晋, 徳善 紀彦, 合田 啓之, 川又 均, 内田 大亮
    • Organizer
      第34回日本口腔診断学会・第31回日本口腔内科学会合同学術大会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] 口腔扁平上皮癌における新規腫瘍マーカーである CXCL13 の発現2021

    • Author(s)
      東條 晋,栗林伸行,中城公一,徳善紀彦,内田大亮
    • Organizer
      第57回日本口腔組織培養学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] 高悪性度口腔扁平上皮癌の遺伝子変異と治療標的の探索2021

    • Author(s)
      徳善紀彦,中城公一,栗林伸行,合田啓之,内田大亮
    • Organizer
      第66回日本口腔外科学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] High frequency of p53 gene mutations in oral squamous cell carcinoma2021

    • Author(s)
      Shin Tojo, Nobuyuki Kuribayashi, Koh-ichi Nakashiro, Norihiko Tokuzen, Hiroyuki Goda, Sayaka Kojima, Hitoshi Kawamata, Daisuke Uchida
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] 口腔扁平上皮癌頸部リンパ節転移予測におけるmicroRNA-375の有用性2021

    • Author(s)
      雑賀将斗,中城公一,徳善紀彦,村上静郁,森野 恵,栗林伸行,合田啓之,内田大亮
    • Organizer
      第45回日本頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] 口腔悪性末梢神経鞘腫瘍における新規融合遺伝子の同定2020

    • Author(s)
      徳善紀彦、中城公一、合田啓之、栗林伸行、内田大亮
    • Organizer
      第 24 回日本がん分子標的治療学会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] Whole-exome sequencing of p53 gene in oral squamous cell carcinoma2020

    • Author(s)
      Nobuyuki Kuribayashi, Koh-ichi Nakashiro, Norihiko Tokuzen, Hiroyuki Goda, Hitoshi Kawamata, Daisuke Uchida
    • Organizer
      第 79 回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] カスタム NGS パネルを用いた口腔扁平上皮癌ゲノム異常の検出2020

    • Author(s)
      中城公一、栗林伸行、東條 晋、徳善紀彦、合田啓之、内田大亮
    • Organizer
      第 44 回日本頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-20H03890
  • [Presentation] 口腔扁平上皮癌における転移関連 microRNA の探索2019

    • Author(s)
      徳善紀彦、中城公一、栗林伸行、合田啓之、内田大亮
    • Organizer
      第38回日本口腔腫瘍学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-18K09816
  • [Presentation] CDCA5 is a novel therapeutic target molecule in oral squamous cell carcinoma2016

    • Author(s)
      Norihiko Tokuzen, Koh-ichi Nakashiro, Hiroshi Tanaka, Kazuki Iwamoto, Hitoshi Akiyama, Hiroyuki Hamakawa
    • Organizer
      AACR Annual Meeting 2016
    • Place of Presentation
      Ernest N. Morial Convention Center, New Orleans, USA
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26861727
  • [Presentation] 口腔扁平上皮癌における新規治療標的分子 CDCA5 の同定2015

    • Author(s)
      徳善紀彦、中城公一、岩本和樹、田中宏史、浜川裕之
    • Organizer
      第19回日本がん分子標的治療学会
    • Place of Presentation
      松山全日空ホテル, 松山市, 愛媛県
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-26861727
  • [Presentation] CDCA5 is a potential therapeutic target for oral squamous cell carcinoma2015

    • Author(s)
      Norihiko Tokuzen, Koh-ichi Nakashiro, Hiroshi Tanaka, Kazuki Iwamoto, Hiroyuki Hamakawa
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場, 名古屋市, 愛知県
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26861727
  • [Presentation] 口腔扁平上皮癌におけるCell Division Cycle Associated 5 の発現機能解析2014

    • Author(s)
      徳善 紀彦
    • Organizer
      第51回日本口腔組織培養学会
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-15
    • Data Source
      KAKENHI-PROJECT-26861727
  • 1.  Nakashiro Koichi (90314880)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 19 results
  • 2.  合田 啓之 (00464371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 3.  内田 大亮 (20335798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 19 results
  • 4.  栗林 伸行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  浜川 裕之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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