Nagasaka Akiomi 長坂明臣

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NAGASAKA AKIOMI 長坂明臣

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Researcher Number	10723877
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 特命講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 神戸大学, 医学研究科, 特命講師 2021: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員 2016 – 2020: 九州大学, 薬学研究院, 助教 2014 – 2016: 九州大学, 薬学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Pharmacology in pharmacy Except Principal Investigator Pharmacology in pharmacy
Keywords	Principal Investigator Gタンパク質共役型受容体 / プロトン感知性受容体 / 血管内皮細胞 / 長期細胞培養 / 生活習慣病 / 血管炎 / マクロファージ / 癌 / 腫瘍関連マクロファージ / 腫瘍 … More / 心肥大退縮 / DREADD / 心退縮 / 心肥大 / Gαタンパク質 / ＧＰＲ４ / 心筋梗塞 / GPR4 … More Except Principal Investigator 細胞外微小環境 / 免疫学 / 循環器・高血圧 / シグナル伝達 / 薬理学 / 炎症 / 免疫細胞 / 心筋梗塞 / 脂質 / G12ファミリー / プロトン感知性受容体 / バイアス型阻害作用 / 阻害薬 / Gタンパク質選択的受容体 / 内皮細胞 / 線維化 / 貪食 / 線維芽細胞 / 抗炎症作用 / 死細胞 / 筋線維芽細胞 Less

血管内皮細胞障害を改善する新規機能分子の取得Principal Investigator
- Principal Investigator
  
  長坂明臣
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kobe University
Acquisition of functional molecules involving the regression of heart hypertrophyPrincipal Investigator
- Principal Investigator
  
  Nagasaka Akiomi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Institute of Physical and Chemical Research
  Kyushu University
Analysis of the roles and interaction of various cells including myofibroblasts involved in fibrosis after myocardial infarction
- Principal Investigator
  
  KUROSE HITOSHI
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyushu University
The physiological roles of proton-sensing GPCRs in tumor-associated macrophagesPrincipal Investigator
- Principal Investigator
  
  Nagasaka Akiomi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyushu University
Investigatation the roles of GPR4 in myocardial infarctionPrincipal Investigator
- Principal Investigator
  
  NAGASAKA AKIOMI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyushu University
Roles of extracellular environment and various cells carrying different function for cardiac fibrosis
- Principal Investigator
  
  KUROSE HITOSHI
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyushu University

All 2023 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid-liquid phase separation2023
- Author(s)
  Horii Yuma、Matsuda Shoichi、Toyota Chikashi、Morinaga Takumi、Nakaya Takeo、Tsuchiya Soken、Ohmuraya Masaki、Hironaka Takanori、Yoshiki Ryo、Kasai Kotaro、Yamauchi Yuto、Takizawa Noburo、Nagasaka Akiomi、Tanaka Akira、Kosako Hidetaka、Nakaya Michio
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-19
- DOI
  10.1038/s41467-023-36189-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-22K06629, KAKENHI-PROJECT-22K07997, KAKENHI-PROJECT-20H03383, KAKENHI-PROJECT-21J11273, KAKENHI-PROJECT-22KJ2466, KAKENHI-PROJECT-22KJ2468
[Journal Article] GRK5‐mediated inflammation and fibrosis exert cardioprotective effects during the acute phase of myocardial infarction2023
- Author(s)
  Nagasaka Akiomi、Terawaki Tsuyoshi、Noda Makoto、Takashima Miyuki、Fujino Mika、Yamauchi Yuto、Arawaka Shigeki、Kato Takeo、Nakaya Michio
- Journal Title
  
  FEBS Open Bio
  
  Volume: 13 Issue: 2 Pages: 380-391
- DOI
  10.1002/2211-5463.13551
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06629, KAKENHI-PROJECT-20H03383
[Journal Article] Increased Expression of Heparan Sulfate 6-O-Sulfotransferase-2 Promotes Collagen Production in Cardiac Myofibroblasts2021
- Author(s)
  Kasai Kotaro、Horii Yuma、Hironaka Takanori、Mae Kyosuke、Ueno Tomoyuki、Nagasaka Akiomi、Nakaya Michio
- Journal Title
  
  BPB Reports
  
  Volume: 4 Issue: 3 Pages: 85-91
- DOI
  10.1248/bpbreports.4.3_85
- NAID
  130008049615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07122, KAKENHI-PROJECT-20H03383, KAKENHI-PROJECT-19J20083, KAKENHI-PROJECT-21J11273
[Journal Article] GPRC5B promotes collagen production in myofibroblasts2021
- Author(s)
  Takizawa Noburo、Hironaka Takanori、Mae Kyosuke、Ueno Tomoyuki、Horii Yuma、Nagasaka Akiomi、Nakaya Michio
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 561 Pages: 180-186
- DOI
  10.1016/j.bbrc.2021.05.035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07122, KAKENHI-PROJECT-20H03383, KAKENHI-PROJECT-19J20083, KAKENHI-PROJECT-21J11273
[Journal Article] Drebrin is induced during myofibroblast differentiation and enhances the production of fibrosis-related genes.2020
- Author(s)
  Hironaka T, Ueno T, Mae K, Yoshimura C, Morinaga T, Horii Y, Nagasaka A, Kurose H, Nakaya M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 529 Issue: 2 Pages: 224-230
- DOI
  10.1016/j.bbrc.2020.05.110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-20H03383, KAKENHI-PROJECT-19J20083
[Journal Article] Efferocytosis during myocardial infarction.2020
- Author(s)
  Yoshimura C, Nagasaka A, Kurose H, Nakaya M.
- Journal Title
  
  J Biochem.
  
  Volume: 68 Issue: 1 Pages: 1-6
- DOI
  10.1093/jb/mvaa051
- NAID
  40022279056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-20H03383
[Journal Article] Leukotriene B4 receptor 1 exacerbates inflammation following myocardial infarction.2020
- Author(s)
  Horii Y, Nakaya M, Ohara H, Nishihara H, Watari K, Nagasaka A, Nakaya T, Sugiura Y, Okuno T, Koga T, Tanaka A, Yokomizo T, Kurose H.
- Journal Title
  
  FASEB Journal
  
  Volume: 印刷中 Issue: 6 Pages: 8749-8763
- DOI
  10.1096/fj.202000041r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-19K07122, KAKENHI-PROJECT-19K07357, KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-20H03383, KAKENHI-PROJECT-19J20083
[Journal Article] マクロファージにおけるpH低下の生理的意義2019
- Author(s)
  長坂明臣、黒瀬等
- Journal Title
  
  細胞
  
  Volume: 51 Pages: 47-50
- Data Source
  KAKENHI-PROJECT-17K15457
[Journal Article] マクロファージにおけるpH低下の生理的意義2018
- Author(s)
  長坂明臣、黒瀬等
- Journal Title
  
  Medical Science Digest
  
  Volume: 44 Pages: 405-409
- Data Source
  KAKENHI-PROJECT-17K15457
[Journal Article] マクロファージにおけるpH感知性GPCRの生理的役割2018
- Author(s)
  長坂明臣、黒瀬等
- Journal Title
  
  アグリバイオ
  
  Volume: 2 Pages: 79-83
- NAID
  40021807743
- Data Source
  KAKENHI-PROJECT-17K15457
[Journal Article] Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction.2017
- Author(s)
  Michio Nakaya,Kenji Watari,Mitsuru Tajima,Takeo Nakaya,Shoichi Matsuda,Hiroki Ohara,Hiroaki Nishihara,Hiroshi Yamaguchi,Akiko Hashimoto,Mitsuho Nishida,Akiomi Nagasaka,Yuma Horii,Hiroki Ono,Gentaro Iribe,Ryuji Inoue,Makoto Tsuda,Kazuhide Inoue,Akira Tanaka,Masahiko Kuroda,Shigekazu Nagata,Hitoshi Kurose
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 127 Issue: 1 Pages: 383-401
- DOI
  10.1172/jci83822
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01383, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-25253011, KAKENHI-PROJECT-16J03451, KAKENHI-PROJECT-26293088, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15K15100, KAKENHI-PROJECT-16K08718, KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-15H04678
[Journal Article] The proton-sensing G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) shows cardioprotective effects against myocardial infarction.2017
- Author(s)
  Nagasaka A, Mogi C, Ono H, Nishi T, Horii Y, Ohba Y, Sato K, Nakaya M, Okajima F, Kurose H.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 7812-7812
- DOI
  10.1038/s41598-017-07573-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09856, KAKENHI-PUBLICLY-17H05510, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-15H04641, KAKENHI-PROJECT-17H03984, KAKENHI-PROJECT-16J04161, KAKENHI-PROJECT-15K06767
[Journal Article] GRK6 phosphorylates IκBα at Ser32/Ser36 and enhances TNF-α-induced inflammation2015
- Author(s)
  Yuki Ohba, Michio Nakaya*, Kenji Watari, Akiomi Nagasaka, & Hitoshi Kurose.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 461 Issue: 2 Pages: 307-313
- DOI
  10.1016/j.bbrc.2015.04.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22136008, KAKENHI-PROJECT-26860056, KAKENHI-PUBLICLY-15H01383, KAKENHI-PROJECT-25253011, KAKENHI-PROJECT-13J03105, KAKENHI-PROJECT-25713007
[Journal Article] Novel functions of GRK6 in macrophages by phosphorylating the non-GPCRs substrates.2015
- Author(s)
  1. Akiomi Nagasaka#, Yuki Ohba#, Hitoshi Kurose, & Michio Nakaya*
- Journal Title
  
  Macrophage
  
  Volume: 2
- DOI
  10.14800/macrophage.1021
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01383, KAKENHI-PROJECT-26860056
[Presentation] The roles of T-cell death-associated gene 8 (TDAG8), a proton-sensing GPCR, in myocardial infarction2019
- Author(s)
  長坂　明臣
- Organizer
  Translational Research on Metabolic and Inflammatory Diseases and Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07122
[Presentation] Smad6を安定化し、BMPシグナルを抑制するユビキチンリガーゼの同定2019
- Author(s)
  廣中貴則、大場悠生、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] プロトン感知性GPCR（GPR4）に着目した心筋梗塞時におけるpH低下の生理的影響の解析2019
- Author(s)
  荻野瑠星、伊藤峻太、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-19K07122
[Presentation] プロトン感知性GPCR（GPR4）に着目した心筋梗塞時におけるpH低下の生理的影響の解析2019
- Author(s)
  荻野瑠星、伊藤峻太、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時におけるプロトン感知性GPCR（GPR4）の役割解析2019
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] Smad6を安定化させ、BMPシグナルを抑制するユビキチンリガーゼの同定2019
- Author(s)
  廣中貴則、大場悠生、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2019
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時におけるプロトン感知性GPCR（GPR4）の役割解析2019
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K15457
[Presentation] Smad6の安定化を介してBMPシグナルを抑制するubiquitin ligaseの同定2018
- Author(s)
  大場悠生、仲矢道雄、廣中貴則、小迫英尊、長坂明臣、黒瀬等
- Organizer
  第17回次世代を担う若手ファーマ・バイオフォーラム2018
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時におけるプロトン感知性GPCR（GPR4）の役割解析2018
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17K15457
[Presentation] BLT1は心筋梗塞時における炎症を悪化させる2018
- Author(s)
  堀井雄真、仲矢道雄、西原弘朗、大原広貴、渡健治、長坂明臣、黒瀬等
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2018
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時におけるプロトン感知性GPCR（GPR4）の役割解析2018
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時におけるプロトン感知性GPCR（GPR4）の役割解析2018
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  生体機能と創薬シンポジウム 2018
- Data Source
  KAKENHI-PROJECT-17K15457
[Presentation] 心筋梗塞時におけるプロトン感知性GPCR（GPR4）の役割解析2018
- Author(s)
  伊藤竣太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  生体機能と創薬シンポジウム　2018
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] Role of proton-sensing GPCR (GPR4) in myocardial infarction2018
- Author(s)
  Shunta Ito, Masaki Hagiwara, Kenji Watari, Toshihide Nishi, Akiomi Nagasaka, Michio Nakaya, Hitoshi Kurose
- Organizer
  Translational Research Metabolic and Inflammatory Diseases and Cancer, Seoul
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] The role of GPR4 in myocardial infarction2018
- Author(s)
  Shunta Ito, Masaki Hagiwara, Kenji Watari, Toshihide Nishi, Akiomi Nagasaka, Michio Nakaya, Hitoshi Kurose
- Organizer
  Translational Research on Metabolic and Inflammatory Diseases, and Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15457
[Presentation] Construction of Gα13-selective designer GPCR2018
- Author(s)
  Masaki Hagiwara, Akiomi Nagasaka, Michio Nakaya, Hitoshi Kurose
- Organizer
  Translational Research Metabolic and Inflammatory Diseases and Cancer, Seoul
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] BLT1 deteriorates inflammation following myocardial infarction2018
- Author(s)
  Yuma Horii, Michio Nakaya, Hiroaki Nishihara, Hiroki Ohara, Kenji Watari, Akiomi Nagasaka, Hitoshi Kurose
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (IUPHAR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時におけるプロトン感知性GPCR（GPR4）の役割解析2018
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  次世代を担う創薬・医療薬理シンポジウム 2018
- Data Source
  KAKENHI-PROJECT-17K15457
[Presentation] GRK2は、Smad6を介してBMPによる骨芽細胞の分化を促進する2017
- Author(s)
  大場悠生、仲矢道雄、小迫英尊、長坂明臣、黒瀬等
- Organizer
  第16回次世代を担う若手ファーマ・バイオフォーラム2017
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] BLT1は心筋梗塞時における炎症を悪化させる2017
- Author(s)
  堀井雄真、仲矢道雄、西原弘朗、大原広貴、渡健治、長坂明臣、黒瀬等
- Organizer
  第70回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] BLT1は心筋梗塞時における炎症を悪化させる2017
- Author(s)
  堀井雄真、仲矢道雄、西原弘朗、大原広貴、渡健治、長坂明臣、黒瀬等
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] pH imaging at infarct area in myocardial infarction2017
- Author(s)
  萩原柾、長坂明臣、伊藤峻太、仲矢道雄、浅沼大祐、廣瀬謙造、黒瀬等
- Organizer
  69th Korean Society of Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] BLT1は心筋梗塞時における炎症を悪化させる2017
- Author(s)
  堀井雄真、仲矢道雄、西原弘朗、大原広貴、渡健治、長坂明臣、黒瀬等
- Organizer
  酸素生物学・ダイイングコード合同若手会議
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞におけるpH低下のin vivoイメージング2017
- Author(s)
  萩原柾、長坂明臣、伊藤峻太、仲矢道雄、浅沼大祐、廣瀬謙造、黒瀬等
- Organizer
  生体機能と創薬シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心肥大時に生じる死細胞はMFG-E8を介して貪食除去される2017
- Author(s)
  松田翔一、仲矢道雄、小宮詩織、長坂明臣、黒瀬等
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市仙台国際センター、東北大学川内北キャンパス
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] BLT1は心筋梗塞時における炎症を悪化させる2017
- Author(s)
  堀井雄真、仲矢道雄、西原弘朗、大原広貴、渡健治、長坂明臣、黒瀬等
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール、長崎新聞文化ホール　アストピア
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] The role of GPR4 in myocardial infarction2017
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  69th Korean Society of Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時におけるプロトン感知性受容体（GPR4）の役割解析2017
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第34回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] The role of GRK2 in BMP signaling2017
- Author(s)
  Yuki Ohba, Michio Nakaya, Akiomi Nagasaka, Hitoshi Kurose
- Organizer
  International Students' Science Camp of Kyushu University KAIST-Kyushu University Joint Seminar
- Place of Presentation
  Shikanoshima, Fukuoka
- Year and Date
  2017-01-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心筋梗塞時におけるプロトン感知性受容体Ｔｃｅｌｌ　ｄｅａｔｈ-ａｓｓｏｃｉａｔｅｄｇｅｎｅ８ (TDAG8) の役割解析2016
- Author(s)
  小野達貴, 西俊英, 長坂明臣, 仲矢道雄, 岡島史和, 黒瀬等
- Organizer
  日本薬学会第131年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26860056
[Presentation] 心肥大時に生じる死細胞はMFG-E8を介して除去される2016
- Author(s)
  松田翔一、仲矢道雄、小宮詩織、長坂明臣、黒瀬等
- Organizer
  第15回　次世代を担う若手ファーマ・バイオフォーラム2016
- Place of Presentation
  大阪大学吹田地区薬学キャンパス
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心筋梗塞におけるpH感知性GPCR（TDAG8）の役割解析2015
- Author(s)
  西俊英、長坂明臣、小野達貴、仲矢道雄、黒瀬等
- Organizer
  第14回生命科学研究会
- Place of Presentation
  三浦市民ホール（三浦市三崎、神奈川）
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心筋梗塞時におけるプロトン感知性受容体（TDAG8）の役割解明2015
- Author(s)
  西俊英、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第８８回　日本薬理学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26860056
[Presentation] 心肥大時に生じるアポトーシス細胞はMFG-E8を介して除去される2014
- Author(s)
  松田翔一、仲矢道雄、小宮詩織、長坂明臣、黒瀬等
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  産業医科大学ラマツィーニホール、福岡
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心肥大におけるMFG-E8の役割解明
- Author(s)
  松田翔一、仲矢道雄、小宮詩織、長坂明臣、黒瀬等
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2014
- Place of Presentation
  大阪、近畿大学
- Year and Date
  2014-08-30 – 2014-08-31
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心筋梗塞時におけるプロトン感知性受容体（TDAG8)の役割解明
- Author(s)
  西俊英、長坂明臣、仲矢道雄、岡島史和、黒瀬等
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25253011

1. KUROSE HITOSHI (10183039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
2. 仲矢道雄 (80464387)

# of Collaborated Projects: 2 results

# of Collaborated Products: 32 results
3. KOGA Tomoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 小迫英尊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 茂木千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagasaka Akiomi 長坂 明臣

NAGASAKA AKIOMI 長坂 明臣

Research Projects

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Co-Researchers

血管内皮細胞障害を改善する新規機能分子の取得Principal Investigator

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Acquisition of functional molecules involving the regression of heart hypertrophyPrincipal Investigator

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Analysis of the roles and interaction of various cells including myofibroblasts involved in fibrosis after myocardial infarction

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The physiological roles of proton-sensing GPCRs in tumor-associated macrophagesPrincipal Investigator

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Investigatation the roles of GPR4 in myocardial infarctionPrincipal Investigator

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Roles of extracellular environment and various cells carrying different function for cardiac fibrosis

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[Journal Article] VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid-liquid phase separation2023

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[Journal Article] GRK5‐mediated inflammation and fibrosis exert cardioprotective effects during the acute phase of myocardial infarction2023

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[Journal Article] Increased Expression of Heparan Sulfate 6-O-Sulfotransferase-2 Promotes Collagen Production in Cardiac Myofibroblasts2021

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NAID

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[Journal Article] GPRC5B promotes collagen production in myofibroblasts2021

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[Journal Article] Drebrin is induced during myofibroblast differentiation and enhances the production of fibrosis-related genes.2020

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[Journal Article] Efferocytosis during myocardial infarction.2020

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NAID

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[Journal Article] Leukotriene B4 receptor 1 exacerbates inflammation following myocardial infarction.2020

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[Journal Article] マクロファージにおけるpH低下の生理的意義2019

Author(s)

Nagasaka Akiomi 長坂明臣

NAGASAKA AKIOMI 長坂明臣