ODA Shingo 織田進吾

Researcher Number	10725534
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2020: 名古屋大学, 医学系研究科, 特任助教 2016 – 2017: 名古屋大学, 医学系研究科, 助教 2015: 名古屋大学, 医学(系)研究科(研究院), 特任助教 2014: 名古屋大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47040:Pharmacology-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy / Applied pharmacology
Keywords	Principal Investigator 肝障害 / 長鎖非コードRNA / 肝星細胞 / microRNA / non-coding RNA / エクソソーム / lncRNA / 肝線維化 / 薬学 / ニューキノロン … More / 薬剤性横紋筋融解症 / フィブラート / スタチン / グルタチオン / 動物モデル / 腎障害 / 骨格筋障害 / 横紋筋融解症 / 医薬品副作用 / 予測試験系 / HepaRG / in vitro / DILI / 薬剤性肝障害 / 細胞アッセイ / 炎症反応 / 炎症 / 免疫 / in vitroアッセイ / 薬物代謝 / 薬物性肝障害 … More Except Principal Investigator マイクロRNA / 薬物性肝障害 / 非実質細胞 / 免疫因子 / エクソソーム / 胆汁うっ滞性肝障害 / 前臨床医薬品開発 / 発症機序 / 特異体質性 / 炎症免疫因子 / 肝障害発症機序 / 動物病態モデル / ハロタン / トログリタゾン / 特異体質性薬物性肝障害 / エクソゾーム / 細胞・組織 / 薬学 / 薬剤反応性 / 血中マイクロRNA / 毒性発現機序 / 酸化ストレス / in vitro cell-based スクリーニング / エナラプリル / ラモトリギン / グルタチオン / 毒性発現予測試験系 / 毒性発現機序解析 / 薬物性腎障害 / microRNA / 肝類洞内皮細胞 / 動物モデル / バイオマーカー / 特異体質性肝障害 / 医薬品開発 / 肝障害予測 / 神経毒性 / セロトニン / ドーパミン / 危険ドラッグ / 合成カチノン Less

Comprehensive functional analysis of lncRNAs in liver fibrosisPrincipal Investigator
- Principal Investigator
  
  織田進吾
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Nagoya University
特異体質性薬物性肝障害発症の個体差の決定因子の解明と予測試験系の開発
- Principal Investigator
  
  横井毅
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya University
Establishment of animal models and treatment methods for drug-induced rhabdomyolysisPrincipal Investigator
- Principal Investigator
  
  Oda Shingo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya University
Establishment of a predictive test system for idiosyncratic drug-induced liver injury and study for evaluation of onset biomarkers
- Principal Investigator
  
  Yokoi Tsuyoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya University
Establishment of a novel cell-based assay for detection of potential drug-induced liver injury by considering immune- and inflammatory-related factorsPrincipal Investigator
- Principal Investigator
  
  ODA Shingo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya University
Mechanisms by which synthetic cathinones induce neurotoxicity
- Principal Investigator
  
  NAKAJIMA Akira
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagoya University

All 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury.2021
- Author(s)
  Shingo Oda, Yuka Uchida, Michael D. Aleo, Petra H. Koza-Taylor, Yusuke Matsui, Masanori Hizue, Lisa D. Marroquin, Jessica Whritenour, Eri Uchida, and Tsuyoshi Yokoi.
- Journal Title
  
  Archives Toxicology
  
  Volume: in press Issue: 1 Pages: 149-168
- DOI
  10.1007/s00204-020-02882-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03388, KAKENHI-PROJECT-18H03207
[Journal Article] Plasma miR-218a-5p as a biomarker for acute cholestatic liver injury in rats and investigation of its pathophysiological roles.2021
- Author(s)
  Shingo Oda, Yuka Hirabuki, Taiki Takeuchi, Takumi Kagawa, and Tsuyoshi Yokoi.
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: in press Issue: 10 Pages: 1537-1552
- DOI
  10.1002/jat.4144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03388
[Journal Article] Exacerbation of gefitinib-induced liver injury by glutathione reduction in mice.2020
- Author(s)
  Shingo Oda, Nanaka Miyazaki, Koichi Tsuneyama, and Tsuyoshi Yokoi.
- Journal Title
  
  Jouranal of Toxicological Sciences
  
  Volume: 45 Pages: 493-502
- NAID
  130007884274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03388
[Journal Article] Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production.2020
- Author(s)
  Reo Kawata, Shingo Oda, Yoshihiro Koya, Hiroaki Kajiyama, and Tsuyoshi Yokoi.
- Journal Title
  
  Toxicology
  
  Volume: 443 Pages: 152544-152544
- DOI
  10.1016/j.tox.2020.152544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03388
[Journal Article] Exacerbation of gefitinib-induced liver injury by glutathione reduction in mice2020
- Author(s)
  Oda Shingo、Miyazaki Nanaka、Tsuneyama Koichi、Yokoi Tsuyoshi
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 45 Issue: 8 Pages: 493-502
- DOI
  10.2131/jts.45.493
- NAID
  130007884274
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-19K07099
[Journal Article] Pharmacological evidence for the involvement of ryanodine receptors in halothane-induced liver injury in mice.2020
- Author(s)
  Ru Jia, Shingo Oda, and Tsuyoshi Yokoi.
- Journal Title
  
  Toxicology
  
  Volume: 443 Pages: 152560-152560
- DOI
  10.1016/j.tox.2020.152560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03388
[Journal Article] Experimental evidence of liver injury by BSEP inhibiting drug with a bile salt supplementation in rats.2019
- Author(s)
  Fuhua Yang, Shingo Oda, Taiki Takeuchi, Koichi Tsuneyama, and Tsuyoshi Yokoi.
- Journal Title
  
  Toxicological Sciences
  
  Volume: 170 Pages: 95-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03388
[Journal Article] Establishment and characterization of a mouse model of rhabdomyolysis by coadministration of statin and fibrate2019
- Author(s)
  Katsuhito Watanabe, Shingo Oda, Akiko Matsubara, Sho Akai, and Tsuyoshi Yokoi
- Journal Title
  
  Toxicology Letters
  
  Volume: 207 Pages: 49-58
- DOI
  10.1016/j.toxlet.2019.03.001
- NAID
  50014569267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15503
[Journal Article] Strain and interindividual differences in lamotrigine-induced liver injury in mice.2019
- Author(s)
  Sho Akai, Shingo Oda, and Tsuyoshi Yokoi.
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 39 Issue: 3 Pages: 451-460
- DOI
  10.1002/jat.3736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03388
[Journal Article] Acute kidney injury model established by systemic glutathione depletion in mice2019
- Author(s)
  Matsubara Akiko、Oda Shingo、Jia Ru、Yokoi Tsuyoshi
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 39 Issue: 6 Pages: 919-930
- DOI
  10.1002/jat.3780
- NAID
  120006718403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15503
[Journal Article] Establishment of a mouse model of troglitazone‐induced liver injury and analysis of its hepatotoxic mechanism2019
- Author(s)
  Jia Ru、Oda Shingo、Tsuneyama Koichi、Urano Yuya、Yokoi Tsuyoshi
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 39 Issue: 11 Pages: 1541-1556
- DOI
  10.1002/jat.3838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-19H03388
[Journal Article] Comprehensive analysis of serum microRNAs in hepatic sinusoidal obstruction syndrome (SOS) in rats: implication as early phase biomarkers for SOS2018
- Author(s)
  Takeuchi Masaki、Oda Shingo、Tsuneyama Koichi、Yokoi Tsuyoshi
- Journal Title
  
  Archives of Toxicology
  
  Volume: 92 Issue: 9 Pages: 2947-2962
- DOI
  10.1007/s00204-018-2269-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-16H02616
[Journal Article] Identification of specific microRNA biomarkers in early stage of hepatocellular injury, cholestasis, and steatosis in rat.2018
- Author(s)
  Takumi Kagawa, Yuji Shirai, Shingo Oda and Tsuyoshi Yokoi
- Journal Title
  
  Toxicol. Sci.
  
  Volume: 166 Issue: 1 Pages: 228-239
- DOI
  10.1093/toxsci/kfy200
- NAID
  130007432275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02616
[Journal Article] Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin2018
- Author(s)
  Akiko Matsubara, Shingo Oda, Sho Akai, Koichi Tsuneyama, Tsuyoshi Yokoi
- Journal Title
  
  Toxicology Letters
  
  Volume: 291 Pages: 184-193
- DOI
  10.1016/j.toxlet.2018.04.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15503, KAKENHI-PROJECT-18K07069
[Journal Article] MicroRNA in rat liver sinusoidal endothelial cells and hepatocytes and application to circulating biomarkers that discern pathogenesis of liver injuries.2018
- Author(s)
  Shingo Oda, Masaki Takeuchi, Sho Akai, Yuji Shirai, Koichi Tsuneyama, and Tsuyoshi Yokoi
- Journal Title
  
  Am. J. Pathol.
  
  Volume: 188 Issue: 4 Pages: 916-928
- DOI
  10.1016/j.ajpath.2017.12.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02616
[Journal Article] Cell-based assay using glutathione-depleted HepaRG human liver cells for predicting drug-induced liver injury.2018
- Author(s)
  Jieyu Xu, Shingo Oda and Tsuyoshi Yokoi
- Journal Title
  
  Toxicol. In Vitro
  
  Volume: 48 Pages: 286-301
- DOI
  10.1016/j.tiv.2018.01.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02616
[Journal Article] Comparative hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice2018
- Author(s)
  Urano Yuya、Oda Shingo、Tsuneyama Koichi、Yokoi Tsuyoshi
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 296 Pages: 185-197
- DOI
  10.1016/j.cbi.2018.09.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-16H02616
[Journal Article] Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice.2017
- Author(s)
  Oda S, Shirai Y, Akai S, Nakajima A, Tsuneyama K, Yokoi T.
- Journal Title
  
  J Appl Toxicol.
  
  Volume: 37 Issue: 5 Pages: 545-553
- DOI
  10.1002/jat.3388
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-16H02616
[Journal Article] Establishment of a mouse model of enalapril-induced liver injury and investigation of the pathogenesis.2017
- Author(s)
  Shirai Y, Oda S, Makino S, Tsuneyama K, Yokoi T.
- Journal Title
  
  Lab Invest.
  
  Volume: in press Issue: 7 Pages: 545-553
- DOI
  10.1038/labinvest.2017.22
- NAID
  120006352182
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-16H02616
[Journal Article] Estabolishment of a novel mouse model for pioglitazone-mediated skeletal muscle injuty.2017
- Author(s)
  Sho Akai, Shingo Oda and Tsuyoshi Yokoi
- Journal Title
  
  Toxicology
  
  Volume: 382 Pages: 1-9
- DOI
  10.1016/j.tox.2017.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02616
[Journal Article] Fluoroquinolones and propionic acid derivatives induce inflammatory responses in vitro2017
- Author(s)
  Akira Nakajima, Hiroki Sato, Shingo Oda, Tsuyoshi Yokoi
- Journal Title
  
  Cell Biology and Toxicology
  
  Volume: 印刷中 Issue: 1 Pages: 65-77
- DOI
  10.1007/s10565-017-9391-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21057
[Journal Article] 薬物代謝・薬物動態研究の最近の動向と展望 -医薬品開発研究を中心として-2017
- Author(s)
  横井毅、織田進吾
- Journal Title
  
  化学と生物
  
  Volume: 印刷中
- NAID
  130006742949
- Data Source
  KAKENHI-PROJECT-15K21057
[Journal Article] A novel cell-based assay for the evaluation of immune- and inflammatory-related gene expression as biomarkers for the risk assessment of drug-induced liver injury.2016
- Author(s)
  Shingo Oda, Kentaro Matsuo, Akira Nakajima, and Tsuyoshi Yokoi.
- Journal Title
  
  Toxicol. Lett.
  
  Volume: 241 Pages: 60-70
- DOI
  10.1016/j.toxlet.2015.10.029
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21057
[Journal Article] Allopurinol induces innate immune responses through mitogen-activated protein kinase signaling pathways in HL-60 cells2016
- Author(s)
  Akira Nakajima, Shingo Oda, Tsuyoshi Yokoi
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 36 Issue: 9 Pages: 1120-1128
- DOI
  10.1002/jat.3272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21057
[Journal Article] MicroRNA-mediated Th2 bias in methimazole-induced acute liver injury in mice2016
- Author(s)
  Yasuaki Uematsu, Sho Akai, Tomoaki Tochitani, Shingo Oda, Toru Yamada, Tsuyoshi Yokoi
- Journal Title
  
  Toxicology and Applied Pharmacology
  
  Volume: 07 Pages: 1-9
- DOI
  10.1016/j.taap.2016.07.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-15K15001
[Journal Article] Zomepirac Acyl Glucuronide Is Responsible for Zomepirac-Induced Acute Kidney Injury in Mice.2016
- Author(s)
  Iwamura A, Watanabe K, Akai S, Nishinosono T, Tsuneyama K, Oda S, Kume T, Yokoi T.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 44 Issue: 7 Pages: 888-96
- DOI
  10.1124/dmd.116.069575
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-15K15001
[Journal Article] いまさら聞けない薬物動態Q＆A: 薬剤師が知っておきたい抱合酵素とその基質について教えてください2016
- Author(s)
  織田進吾, 横井　毅
- Journal Title
  
  月刊薬事
  
  Volume: 58 Pages: 685-690
- Data Source
  KAKENHI-PROJECT-15K21057
[Journal Article] いまさら聞けない薬物動態Q＆A. 薬剤師が知っておきたい抱合酵素とその基質について教えてください2016
- Author(s)
  織田進吾, 横井　毅
- Journal Title
  
  月刊薬事
  
  Volume: 58 Pages: 685-690
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] The involvement of ryanodine receptors in halothane-induced liver injury in mice.2021
- Author(s)
  Ru Jia, Shingo Oda, Tsuyoshi Yokoi.
- Organizer
  60th Annual Meeting of Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03388
[Presentation] Exploration of small RNA biomarkers in serum exosomes for testicular injury in rats.2021
- Author(s)
  Reo Kawata, Takumi Kagawa, Shingo Oda, Tsuyoshi Yokoi.
- Organizer
  60th Annual Meeting of Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03388
[Presentation] ラットにおける胆汁うっ滞性肝障害のバイオマーカーとしての miR 218a 5p の有用性及びその機能解析2020
- Author(s)
  平吹有香，織田進吾，武内太輝，香川匠，横井毅
- Organizer
  第2回医薬品毒性機序研究会
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] ラットにおける胆汁うっ滞性肝障害のバイオマーカーとしてのmiR-2048a-5p の有用性及びその機能解析2020
- Author(s)
  平吹有香、織田進吾、武内太輝、香川匠、横井毅
- Organizer
  第2回医薬品毒性機序研究会
- Data Source
  KAKENHI-PROJECT-19H03388
[Presentation] An in vitro coculture system of human PBMCs with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury.2020
- Author(s)
  Shingo Oda, Yuka Uchida, Michael D. Aleo, Petra H. Koza-Taylor, Masanori Hizue, Lisa D. Marroquin, Jessica Whritenour, Eri Uchida, Tsuyoshi Yokoi.
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H03388
[Presentation] Investigation of pathophysiological roles of miR-218a-5p in cholestatic liver injury in rats.2020
- Author(s)
  Yuka Hirabuki, Shingo Oda, Taiki Takeuchi, Takumi Kagawa, Tsuyoshi Yokoi.
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H03388
[Presentation] ラットにおける胆汁うっ滞性肝障害のバイオマーカーとしての miR-218a-5p の有用性及びその機能解析2020
- Author(s)
  平吹有香，織田進吾，武内太輝，香川匠，横井毅
- Organizer
  第２回医薬品毒性機序研究会
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] Transcriptomic landscape in murine plasma of hepatocellular liver injury for biomarker discovery2019
- Author(s)
  Shingo Oda, Ken Ito, Tsuyoshi Yokoi
- Organizer
  15th IUTOX
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] Application of microRNAs derived from liver sinusoidal endothelial cells to circulating biomarkers that discern pathogenesis of liver injuries.2019
- Author(s)
  Shingo Oda, Masaki Takeuchi, Sho Akai, Yuji Shirai, and Tsuyoshi Yokoi.
- Organizer
  58th Annual Meeting of Society of Toxicology, March 10-14, 2019, Baltimore Convention Center, Baltimore, Maryland, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Transcirptomic landscape in murine plasma of hepatocellular liver injury for biomarker discovery.2019
- Author(s)
  Shingo Oda, Ken Itoh, and Tsuyoshi Yokoi.
- Organizer
  IUTOX 15th International Congress of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03388
[Presentation] 胆汁酸塩経口負荷ラットにおける薬剤性肝障害の評価2019
- Author(s)
  織田進吾, 楊馥華, 武内太輝, 横井毅
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] 胆汁酸塩経口負荷ラットにおける薬剤性肝障害の評価.2019
- Author(s)
  織田進吾, 楊馥華, 武内太輝, 横井毅.
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03388
[Presentation] Analysis of PlaAnalysis of plasma MicroRNAs as Biomarkers for Drug-induced Cholestatic Liver Injury in Rats.2019
- Author(s)
  平吹有香、織田進吾、武内太輝、香川匠、横井毅.
- Organizer
  第34回日本薬物動態学会年会
- Data Source
  KAKENHI-PROJECT-19H03388
[Presentation] 薬剤性肝障害動物モデルにおけるバイオマーカーとしての血中マイクロRNAの利用2019
- Author(s)
  織田進吾
- Organizer
  安全性評価研究会　第28回夏フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] 胆汁うっ滞性肝障害ラットのバイオマーカーとしてのmicroRNA探索2019
- Author(s)
  平吹有香，織田進吾，武内太輝，香川匠，横井毅
- Organizer
  日本薬物動態学会第34回年会
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] Establishment of a novel mouse model of troglitazone-induced liver injury and analysis of its hepatotoxic mechanism.2019
- Author(s)
  Ru Jia, Shingo Oda, Koichi Tsuneyama, Yuya Urano, Tsuyoshi Yokoi.
- Organizer
  第1回日本毒性学会医薬品毒性機序研究会
- Data Source
  KAKENHI-PROJECT-19H03388
[Presentation] Gefitinib及びNaphthalene誘導性肺障害モデルマウスを用いたバイオマーカーとしての血中miRNA探索.2019
- Author(s)
  大矢寛子，織田進吾，横井毅.
- Organizer
  第46回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H03388
[Presentation] Systemic glutathione depletion causes acute kidney injury.2018
- Author(s)
  Akiko Matsubara, Shingo Oda, Ru Jia, and Tsuyoshi Yokoi.
- Organizer
  International Meeting of 22nd Microsomes and Drug Oxidations and 33rd Japanese Society of the Study of Xenobiotics, October 1-5, 2018, Ishikawa Ongakudo Hall, Kanazawa, Ishikawa, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] 病型および臓器特異的な毒性予測バイオマーカーとしてのmiRNA2018
- Author(s)
  横井　毅、香川　匠、　織田進吾
- Organizer
  2018年7月18日-７月20日、第45回日本毒性学会学術年会、大阪国際会議場グランキューブ大阪、大阪府大阪市
- Invited
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] 全身性グルタチオン枯渇は急性腎障害を引き起こす2018
- Author(s)
  松原明子, 織田進吾, 横井毅
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-17K15503
[Presentation] 胆汁うっ滞および脂肪肝を病型別に早期予測が可能な血漿miRNAバイオマーカー探索研究．2018
- Author(s)
  香川　匠、白井勇司、Tomas ZARYBNICKY、織田進吾、横井　毅
- Organizer
  2018年7月18日-７月20日、第45回日本毒性学会学術年会、大阪国際会議場グランキューブ大阪、大阪府大阪市
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] ゲフィチニブ誘導性肝障害マウスモデルの作成及びグルタチオン枯渇の影響．2018
- Author(s)
  織田進吾、宮崎菜々華、賈茹、常山幸一、横井　毅
- Organizer
  2018年7月18日-７月20日、第45回日本毒性学会学術年会、大阪国際会議場グランキューブ大阪、大阪府大阪市
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Establishment of gefitinib-induced liver injury and its pathogenic mechanisms in mice.2018
- Author(s)
  Shingo Oda, Nanaka Miyazaki, Ru Jia, Koichi Tsuneyama, and Tsuyoshi Yokoi.
- Organizer
  The 8th International Congress of Asian Society of Toxicology, June 17-20, 2018, The Royal Cliff Grand Hotel, Pattaya, Thailand.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Individual variability of carbamazepine-induced liver injury in mice.2017
- Author(s)
  Yasuaki Uematsu, Sho Akai, Shingo Oda, Toru Yamada, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology, March 12-16, 2017, Baltimore Convention Center, Baltimore, Maryland, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Characterization of microRNAome in rat liver sinusoidal endothelial cells and hepatocytes and their potential application to plasma biomarkers that discern pathogenesis of liver injuries2017
- Author(s)
  Shingo Oda, Masataka Takeuchi, Yuji Shirai, Sho Akai, Koichi Tsuneyama, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology, March 12-16, 2017, Baltimore Convention Center, Baltimore, Maryland, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Individual variability of carbamazepine-induced liver injury in mice2017
- Author(s)
  Yasuaki Uematsu, Sho Akai, Shingo Oda, Toru Yamada, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Establishment of a mouse model of rhabdomyolysis by combined use of ciprofloxacin and atorvastatin2017
- Author(s)
  Akiko Matsubara, Shingo Oda, Sho Akai, Tsuyoshi Yokoi
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-17K15503
[Presentation] Characterization of microRNAome in rat liver sinusoidal endothelial cells and hepatocytes and their potential application to plasma biomarkers that discern pathogenesis of liver injuries2017
- Author(s)
  Shingo Oda, Masataka Takeuchi, Yuji Shirai, Sho Akai, Koichi Tsuneyama, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Comparison of in vitro cytotoxicity assays using glutathione-depleted HepaRG and HepG2 cells for predicting drug-induced liver injury.2017
- Author(s)
  Jieyu Xu, Shingo Oda, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Comparison of in vitro cytotoxicity assays using glutathione-depleted HepaRG and HepG2 cells for predicting drug-induced liver injury2017
- Author(s)
  Jieyu Xu, Shingo Oda, Tsuyoshi Yokoi
- Organizer
  56th Annual Meeting of Society of Toxicology
- Place of Presentation
  Baltimore Convention Center (Baltimore, USA)
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] Establishment of a novel cell-based assay for drug-induced liver injury (DILI) potential considering immune- and inflammation-related factors.2017
- Author(s)
  Tsuyoshi Yokoi and Shingo Oda.
- Organizer
  56th Annual Meeting of Society of Toxicology, March 12-16, 2017, Baltimore Convention Center, Baltimore, Maryland, USA.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] 抗菌薬シプロフロキサシン及びアトルバスタチンの併用による横紋筋融解症マウスモデルの作出2017
- Author(s)
  松原明子、織田進吾、赤井翔、横井毅
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-17K15503
[Presentation] Characterization of microRNAome in rat liver sinusoidal endothelial cells and hepatocytes and their potential application to plasma biomarkers that discern pathogenesis of liver injuries2017
- Author(s)
  Shingo Oda, Masataka Takeuchi, Yuji Shirai, Sho Akai, Koichi Tsuneyama, Tsuyoshi Yokoi
- Organizer
  56th Annual Meeting of Society of Toxicology
- Place of Presentation
  Baltimore Convention Center (Baltimore, USA)
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] Comparison of in vitro cytotoxicity assays using glutathione-depleted HepaRG and HepG2 cells for predicting drug-induced liver injury.2017
- Author(s)
  Jieyu Xu, Shingo Oda, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology, March 12-16, 2017, Baltimore Convention Center, Baltimore, Maryland, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Establishment and characterization of a mouse model of rhabdomyolysis by administration of statin and fibrate.2017
- Author(s)
  Katsuhiro Watanabe, Shingo Oda, Sho Akai, Akiko Matsubara, and Tsuyoshi Yokoi.
- Organizer
  21th North American ISSX Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] 薬剤性肝障害リスク評価におけるグルタチオン枯渇HepaRG細胞の有用性検討2016
- Author(s)
  許潔玉、織田進吾、横井毅
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  愛知県産業労働センターウインクあいち (愛知県名古屋市)
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] ジクロフェナク誘導性肝障害モデルマウスにおけるアシルグルクロン酸代謝物の毒性学的役割の検討2016
- Author(s)
  織田進吾、白井勇司、赤井翔、常山幸一、中島晶、横井毅
- Organizer
  第23回HAB研究機構学術大会
- Place of Presentation
  つくば産業総合技術研究所共用講堂 (茨城県つくば市)
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] In vitro試験系における抗菌剤レボフロキサシンおよび解熱鎮痛消炎剤ロキソプロフェンによる免疫因子の活性化2016
- Author(s)
  中島晶, 佐藤宏樹、織田進吾、横井毅
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  愛知県産業労働センターウインクあいち (愛知県名古屋市)
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] Toxicological role of acylglucuronide metabolite in diclofenac-induced acute liver injury in mice2016
- Author(s)
  Shingo Oda, Yuji Shirai, Sho Akai, Akira Nakajima, Koichi Tsuneyama, Tsuyoshi Yokoi
- Organizer
  The 11th International ISSX Meeting
- Place of Presentation
  BEXCO Convention Center (Busan, Republic of Korea)
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] Mechanisms of drug-induced liver injury (DILI) and establishment of a novel cell-based assay for DILI potential considering immune- and inflammatory-related factors2015
- Author(s)
  Shingo Oda, Tsuyoshi Yokoi
- Organizer
  日本薬物動態学会第30回年会
- Place of Presentation
  タワーホール船堀 (東京都江戸川区)
- Year and Date
  2015-11-12
- Invited
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] HepaRG細胞および免疫・炎症関連遺伝子マーカーを用いた薬剤性肝障害リスク評価系の構築2015
- Author(s)
  織田進吾, 松尾研太朗, 深見達基, 中島美紀, 横井毅
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  石川県立音楽堂/金沢市アートホール/ホテル日航金沢 (石川県金沢市)
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-15K21057

1. Yokoi Tsuyoshi (70135226)

# of Collaborated Projects: 3 results

# of Collaborated Products: 40 results
2. NAKAJIMA Akira (20419237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SHIRAI Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. XU Jieyu

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 常山幸一

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results

ODA Shingo 織田 進吾

Research Projects

Research Products

Co-Researchers

Comprehensive functional analysis of lncRNAs in liver fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

特異体質性薬物性肝障害発症の個体差の決定因子の解明と予測試験系の開発

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Establishment of animal models and treatment methods for drug-induced rhabdomyolysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of a predictive test system for idiosyncratic drug-induced liver injury and study for evaluation of onset biomarkers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of a novel cell-based assay for detection of potential drug-induced liver injury by considering immune- and inflammatory-related factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms by which synthetic cathinones induce neurotoxicity

Principal Investigator

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Research Institution

[Journal Article] An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury.2021

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[Journal Article] Plasma miR-218a-5p as a biomarker for acute cholestatic liver injury in rats and investigation of its pathophysiological roles.2021

Author(s)

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DOI

Data Source

[Journal Article] Exacerbation of gefitinib-induced liver injury by glutathione reduction in mice.2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production.2020

Author(s)

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DOI

Data Source

[Journal Article] Exacerbation of gefitinib-induced liver injury by glutathione reduction in mice2020

Author(s)

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NAID

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Language

Data Source

[Journal Article] Pharmacological evidence for the involvement of ryanodine receptors in halothane-induced liver injury in mice.2020

Author(s)

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DOI

Data Source

[Journal Article] Experimental evidence of liver injury by BSEP inhibiting drug with a bile salt supplementation in rats.2019

Author(s)

Journal Title

Data Source

[Journal Article] Establishment and characterization of a mouse model of rhabdomyolysis by coadministration of statin and fibrate2019

Author(s)

Journal Title

ODA Shingo 織田進吾