Oohara Kinuyo 大原絹代

… Alternative Names

OHARA Kinuyo 大原絹代

Less

Researcher Number	10731606
Other IDs
Affiliation (Current)	2025: 日本大学, 歯学部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 日本大学, 歯学部, 助教 2015 – 2021: 日本大学, 歯学部, 専修医 2014: 日本大学, 歯学部, ポスト・ドクトラル・フェロー
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / Conservative dentistry Except Principal Investigator Basic Section 57050:Prosthodontics-related / Prosthodontics/ Dental materials science and
Keywords	Principal Investigator 歯髄炎 / TLR4 / 三叉神経節細胞 / 三叉神経節 / 異所性疼痛 / MAPキナーゼ / NFkB / 異所性異常疼痛 / TLR４ / 三叉神経説細胞 / 関連痛 / 異所性疼痛異常 / NFｋB … More Except Principal Investigator … More 感覚異常 / 口腔乾燥 / 口腔粘膜 / 三叉神経 / 活性酸素種 / 唾液 / 疼痛 / 義歯 / 免疫組織学的解析 / 下歯槽神経損傷モデルラット / グリア細胞 / 三叉神経節細胞 / 下歯槽神経損傷 / 口腔顔面痛 / 神経障害性疼痛 / 一酸化窒素 / 逃避閾値反射 / 免疫組織化学的解析 / 下歯槽神経損傷モデル / 衛星細胞 / 異常疼痛 Less

口腔乾燥に起因する口腔粘膜感覚異常の発症機構と活性酸素種の関与
- Principal Investigator
  
  李淳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Nihon University
歯髄炎に起因した異所性異常疼痛に対する三叉神経節細胞間のマクロファージの関与Principal Investigator
- Principal Investigator
  
  大原絹代
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Nihon University
The mechanism of pain caused by oral mucosal ulcers associated with dry mouth
- Principal Investigator
  
  LEE Jun
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Nihon University
Molecular mechanisms of cellular functional interaction in the trigeminal ganglion underlying ectopic persistent pain associated with tooth pulp inflammationPrincipal Investigator
- Principal Investigator
  
  OHARA KINUYO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Nihon University
口腔粘膜の神経障害性疼痛に対する新規補綴処置を目指した基礎研究
- Principal Investigator
  
  LEE Jun
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  Nihon University
The molecular mechanisms of intra-cellular interaction in the trigeminal ganglion underlying ectopic pain associated with tooth pulp inflammationPrincipal Investigator
- Principal Investigator
  
  OHARA Kinuyo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Nihon University
The nerve mechanisms underlying tongue-referred pain associated with tooth pulp inflammation in trigeminal ganglion cellsPrincipal Investigator
- Principal Investigator
  
  OHARA Kinuyo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Conservative dentistry
- Research Institution
  Nihon University

All 2023 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

[Book] 抜髄 Initial Treatment 治癒に導くための歯髄への臨床アプローチ2016
- Author(s)
  木ノ本喜史,興地隆史,大島勇人,澁川義幸,田崎雅和,村松敬,五十嵐勝,北島佳代子,新井恭子,松浦信幸,長谷川誠実,清水康平,羽鳥啓介,大原絹代,篠田雅路,小木曾文内,泉英之,阿部修,加藤広之,澤田則宏,佐藤暢也,岩波洋一,佐藤勧哉,北村和夫,吉川剛正,田中利典,石井宏,清水花織
- Total Pages
  399
- Publisher
  ヒョーロン
- Data Source
  KAKENHI-PROJECT-16K20466
[Journal Article] Involvement of Satellite Cell Activation via Nitric Oxide Signaling in Ectopic Orofacial Hypersensitivity2020
- Author(s)
  Lee Jun、Ohara Kinuyo、Shinoda Masamichi、Hayashi Yoshinori、Kubo Asako、Sugawara Shiori、Asano Sayaka、Soma Kumi、Kanno Kohei、Ando Masatoshi、Koyama Ryo、Kimura Yuki、Sakanashi Kousuke、Iinuma Toshimitsu、Iwata Koichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 4 Pages: 1252-1252
- DOI
  10.3390/ijms21041252
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09732, KAKENHI-PROJECT-19K10049, KAKENHI-PROJECT-18K17077, KAKENHI-PROJECT-16K11477
[Journal Article] Upregulation of calcitonin gene-related peptide, neuronal nitric oxide synthase, and phosphorylated extracellular signal-regulated kinase 1/2 in the trigeminal ganglion after bright light stimulation of the eye in rats2019
- Author(s)
  Okada S, Saito H, Matsuura Y, Mikuzuki L, Ohara K, Lee J, Iinuma T, Katagiri A *, Iwata K
- Journal Title
  
  Journal of Oral Science
  
  Volume: 61 Issue: 1 Pages: 146-155
- DOI
  10.2334/josnusd.18-0031
- NAID
  130007626634
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11855, KAKENHI-PROJECT-18K17077
[Journal Article] Differential activation of ascending noxious pathways associated with trigeminal nerve injury.2019
- Author(s)
  Okada S, Katagiri A *, Saito H, Lee J, Ohara K, Iinuma T, Bereiter DA, and Iwata K.
- Journal Title
  
  Pain
  
  Volume: - Issue: 6 Pages: 1342-1360
- DOI
  10.1097/j.pain.0000000000001521
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11855, KAKENHI-PROJECT-18K17077
[Journal Article] Role of medullary astroglial glutamine synthesis in tooth pulp hypersensitivity associated with frequent masseter muscle contraction2018
- Author(s)
  Watase Tetsuro、Shimizu Kohei、Ohara Kinuyo、Komiya Hiroki、Kanno Kohei、Hatori Keisuke、Noma Noboru、Honda Kuniya、Tsuboi Yoshiyuki、Katagiri Ayano、Shinoda Masamichi、Ogiso Bunnai、Iwata Koichi
- Journal Title
  
  Mol pain
  
  Volume: 14 Pages: 1-11
- DOI
  10.1177/1744806918763270
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11566, KAKENHI-PROJECT-17K09043, KAKENHI-PROJECT-15K20415, KAKENHI-PROJECT-16K20466
[Journal Article] Involvement of transient receptor potential vanilloid 1 channel expression in orofacial cutaneous hypersensitivity following tooth pulp inflammation.2018
- Author(s)
  Watase T, Shimizu K, Komiya H, Ohara K, Iwata K, Ogiso B.
- Journal Title
  
  J Oral Sci
  
  Volume: 60 Pages: 8-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K20466
[Journal Article] Phenotypic change in trigeminal ganglion neurons associated with satellite cell activation via extracellular signal-regulated kinase phosphorylation is involved in lingual neuropathic pain2017
- Author(s)
  Mikuzuki Lou、Saito Hiroto、Katagiri Ayano、Okada Shinji、Sugawara Shiori、Kubo Asako、Ohara Kinuyo、Lee Jun、Toyofuku Akira、Iwata Koichi
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 46 Issue: 6 Pages: 2190-2202
- DOI
  10.1111/ejn.13667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11881, KAKENHI-PROJECT-17K11855, KAKENHI-PROJECT-16K20466
[Journal Article] Ascending projections of nociceptive neurons from trigeminal subnucleus caudalis: A population approach.2017
- Author(s)
  Saito H, Katagiri A, Okada S, Mikuzuki L, Kubo A, Suzuki T, Ohara K, Lee J, Gionhaku N, Iinuma T, Bereiter DA, Iwata K.
- Journal Title
  
  Experimantal Neurology
  
  Volume: 293 Pages: 124-136
- DOI
  10.1016/j.expneurol.2017.03.024
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21410, KAKENHI-PROJECT-15K11272, KAKENHI-PROJECT-16K11636, KAKENHI-PROJECT-16K20466, KAKENHI-PROJECT-17K11855
[Journal Article] Interaction between calcitonin gene-related peptide-immunoreactive neurons and satellite cells via P2Y(12) R in the trigeminal ganglion is involved in neuropathic tongue pain in rats.2017
- Author(s)
  Sugawara S, Okada S, Katagiri A, Saito H, Suzuki T, Komiya H, Kanno K, Ohara K, Iinuma T, Toyofuku A, Iwata K.
- Journal Title
  
  Eur J Oral Sci.
  
  Volume: 125(6) Issue: 6 Pages: 444-452
- DOI
  10.1111/eos.12382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11881, KAKENHI-PROJECT-17K11855, KAKENHI-PROJECT-16K20466
[Journal Article] Role of Neuron-Glial Interaction Mediated by IL-1β in Ectopic Tooth Pain2017
- Author(s)
  Komiya H.、Shimizu K.、Noma N.、Tsuboi Y.、Honda K.、Kanno K.、Ohara K.、Shinoda M.、Ogiso B.、Iwata K.
- Journal Title
  
  J Dent Res
  
  Volume: 97 Issue: 4 Pages: 467-475
- DOI
  10.1177/0022034517741253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11566, KAKENHI-PROJECT-17K09043, KAKENHI-PROJECT-18K17077
[Journal Article] 歯内療法における打診痛を考察する2016
- Author(s)
  清水康平，羽鳥啓介，大原絹代，篠田雅路，小木曾文内
- Journal Title
  
  日本歯科評論
  
  Volume: 76(3) Pages: 47-58
- Data Source
  KAKENHI-PROJECT-26893288
[Journal Article] Involvement of trigeminal transition zone and laminated subnucleus caudalis in masseter muscle hypersensitivity associated with tooth inflammation.2014
- Author(s)
  Shimizu K, Matsumoto K, Noma N, Matsuura S, Ohara K, Komiya H, Watase T, Ogiso B, Tsuboi Y, Shinoda M, Hatori K, Nakaya Y, Iwata K.
- Journal Title
  
  PLoS　One
  
  Volume: 9 Pages: 1-11
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26893288
[Presentation] 再活性化Epstein-BarrウィルスはRANKLの産生を誘導する2023
- Author(s)
  宮田泰伎, 田村隆仁, 大原絹代, 安川拓也, 林誠, 武市収
- Organizer
  日本歯科保存学会2023年度春季学術大会(第158回)
- Data Source
  KAKENHI-PROJECT-22K10008
[Presentation] Spinal Cord Microglial Phenotypic Changes Following Sciatic Nerve Crush in CD137LKO Mice2019
- Author(s)
  David Nicholas, Kinuyo Ohara, Ling Cao
- Organizer
  Eastern Pain Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17077
[Presentation] Involvement of satellite cell activation underlying nitric oxide mechanisms in ectopic orofacial pain2017
- Author(s)
  Jun Lee, Kinuyo Ohara, Masamichi Shinoda, Toshimitsu Iinuma and Koichi Iwata
- Organizer
  10th Congress of the European Pain Federation EFIC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11636
[Presentation] 急性歯髄炎により誘導される歯痛錯誤の末梢神経機構2017
- Author(s)
  古宮宏記, 清水康平, 大原絹代, 髙橋なつみ, 小木曾文内
- Organizer
  日本歯科保存学会春季学術大会
- Data Source
  KAKENHI-PROJECT-16K20466
[Presentation] 急性歯髄炎により誘導される歯痛錯誤の末梢神経機構2016
- Author(s)
  古宮宏記, 清水康平, 大原絹代, 小林寛, 會田泰代, 小木曾文内
- Organizer
  日本歯科保存学会 2016 年度春季学術大会（第 144 回）
- Place of Presentation
  栃木県総合文化センター(栃木県宇都宮市)
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-16K20466
[Presentation] Toll-like receptor 4 in the trigeminal sensory neurons is involved in tongue-referred pain following tooth pulp inflammation2015
- Author(s)
  Kinuyo Ohara, Kohei Shimizu, Masamichi Shinoda, Bunnai Ogiso and Koichi Iwata
- Organizer
  9th Congress of the European Pain Federation EFIC
- Place of Presentation
  Vienna(AUSTRIA)
- Year and Date
  2015-09-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893288
[Presentation] Toll-like receptor 4 in the trigeminal sensory neurons is involved in tongue-referred pain following tooth pulp inflammation
- Author(s)
  Kinuyo Ohara, Kohei Shimizu, Masamichi Shinoda, J Lee, Bunnai Ogiso and Koichi Iwata
- Organizer
  9th Congress of the EUROPIAN PAIN FEDERATION EFIC
- Place of Presentation
  VIENNA, AUSTRIA
- Year and Date
  2015-09-02 – 2015-09-05
- Data Source
  KAKENHI-PROJECT-26893288
[Presentation] 歯髄の炎症はToll-like Receptor４の働きを介して舌の異常疼痛を誘導する
- Author(s)
  大原　絹代,　清水　康平,　林　誠，　井比　陽菜，　小木曾　文内
- Organizer
  日本歯科保存学会秋季学術大会(第141回)
- Place of Presentation
  山形テルサ(山形県山形市)
- Year and Date
  2014-10-30 – 2014-10-31
- Data Source
  KAKENHI-PROJECT-26893288

1. LEE Jun (10386055)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. 岡田真治 (60844008)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 片桐綾乃 (40731899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. SHIMIZU Kohei

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. HONDA Kuniya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 岩田幸一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 篠田雅路

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. 久保亜抄子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 豊福明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Oohara Kinuyo 大原 絹代

OHARA Kinuyo 大原 絹代

Research Projects

Research Products

Co-Researchers

口腔乾燥に起因する口腔粘膜感覚異常の発症機構と活性酸素種の関与

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

歯髄炎に起因した異所性異常疼痛に対する三叉神経節細胞間のマクロファージの関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of pain caused by oral mucosal ulcers associated with dry mouth

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of cellular functional interaction in the trigeminal ganglion underlying ectopic persistent pain associated with tooth pulp inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

口腔粘膜の神経障害性疼痛に対する新規補綴処置を目指した基礎研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The molecular mechanisms of intra-cellular interaction in the trigeminal ganglion underlying ectopic pain associated with tooth pulp inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The nerve mechanisms underlying tongue-referred pain associated with tooth pulp inflammation in trigeminal ganglion cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 抜髄 Initial Treatment 治癒に導くための歯髄への臨床アプローチ2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Involvement of Satellite Cell Activation via Nitric Oxide Signaling in Ectopic Orofacial Hypersensitivity2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Upregulation of calcitonin gene-related peptide, neuronal nitric oxide synthase, and phosphorylated extracellular signal-regulated kinase 1/2 in the trigeminal ganglion after bright light stimulation of the eye in rats2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Differential activation of ascending noxious pathways associated with trigeminal nerve injury.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of medullary astroglial glutamine synthesis in tooth pulp hypersensitivity associated with frequent masseter muscle contraction2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of transient receptor potential vanilloid 1 channel expression in orofacial cutaneous hypersensitivity following tooth pulp inflammation.2018

Author(s)

Journal Title

Data Source

[Journal Article] Phenotypic change in trigeminal ganglion neurons associated with satellite cell activation via extracellular signal-regulated kinase phosphorylation is involved in lingual neuropathic pain2017

Oohara Kinuyo 大原絹代

OHARA Kinuyo 大原絹代