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Takahashi Masahiro  高橋 正皓

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TAKAHASHI MASAHIRO  高橋 正皓

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Researcher Number 10736713
Other IDs
Affiliation (Current) 2025: 神奈川歯科大学, 歯学部, 診療科准教授
2025: 昭和大学, 歯学部, 兼任講師
Affiliation (based on the past Project Information) *help 2023 – 2024: 神奈川歯科大学, 歯学部, 診療科准教授
2022 – 2023: 神奈川歯科大学, 歯学部, 講師
2018 – 2022: 昭和大学, 歯学部, 講師
2014 – 2018: 昭和大学, 歯学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 57070:Developmental dentistry-related / Orthodontics/Pediatric dentistry
Except Principal Investigator
Basic Section 57070:Developmental dentistry-related / Orthodontics/Pediatric dentistry
Keywords
Principal Investigator
遺伝子解析 / 唇顎口蓋裂 / 裂型 / 顎顔面形態 / CBCT / エピジェネティクス / Down症候群 / 遺伝子 / ゲノム / 歯学 … More / 一卵性双生児不一致症例 / DNAメチル化解析 / 非症候性唇顎口蓋裂 / ホールゲノムシーケンス / 全ゲノムシーケンス解析 / 一卵性双生児 / 骨芽細胞 / 再生医療 / 細胞移植 / 硬組織再生 / 神経堤由来細胞 … More
Except Principal Investigator
ゲノム / 遺伝子 / ヒトゲノム / 一塩基多型 / ヒト / 全エクソンシーケンス / 過剰歯 / 家族性 / シークエンス / exome / 癒合歯 / 側面頭部X線規格写真 / 顎顔面形態 / ゲノム解析 / コーンビームCT / セファロ / 顎顔面頭蓋 / 咬合異常 / 遺伝因子 / 歯冠長 / 歯根長 / 候補遺伝子 / 歯冠 / 歯根 / 家系 Less
  • Research Projects

    (9 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (11 People)
  •  DNAメチル化アレイ解析を用いた唇顎口蓋裂における裂型決定因子の同定Principal Investigator

    • Principal Investigator
      高橋 正皓
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Kanagawa Dental College
  •  Comprehensive analysis for responsible gene of fused teeth using exome sequencing

    • Principal Investigator
      Yamaguchi Tetsutaro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Kanagawa Dental College
  •  Down症候群の顎顔面形態に関連する遺伝的要因の解明と3次元形態解析Principal Investigator

    • Principal Investigator
      高橋 正皓
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Kanagawa Dental College
      Showa University
  •  Three-dimensional assessment and elucidation of gene factor in craniofacial morphology for patients with orofacial cleftsPrincipal Investigator

    • Principal Investigator
      Takahashi Masahiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Showa University
  •  Genome-wide analysis of maxillofacial morphology of 1000 individuals with cephalograms

    • Principal Investigator
      Yamaguchi Tetsutaro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Kanagawa Dental College
      Showa University
  •  Elucidation of genetic factors related to root traits

    • Principal Investigator
      Maki Koutaro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Showa University
  •  Human genome analysis for impacted supernumerary teeth in the region of maxillary incisor

    • Principal Investigator
      Yamaguchi Tetsutaro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Showa University
  •  Exploration of new factors associated with non-syndromic cleft lip and palate using epigenome analysisPrincipal Investigator

    • Principal Investigator
      Takahashi Masahiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Showa University
  •  Development of new cell transplantation therapy for cleft alveolar bonePrincipal Investigator

    • Principal Investigator
      TAKAHASHI MASAHIRO
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Showa University

All 2023 2022 2020 2019 2018 2017 2015 2014

All Journal Article Presentation

  • [Journal Article] Comparison of the maxillary sinus size of adult Korean individuals with different skeletal patterns using cone-beam computed tomography.2023

    • Author(s)
      Mitsuda C, Takahashi M, Kim Y-I, Takeda M, Hatanaka R, Sambe T, Yamaguchi T
    • Journal Title

      神奈川歯科大学学会雑誌

      Volume: 58 Pages: 99-104

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K10173
  • [Journal Article] Three-Dimensional Assessment of Craniofacial Features in Patients With Down Syndrome During the Mixed Dentition Period: A Case-Control Study2022

    • Author(s)
      Takizawa Hideomi, Takahashi Masahiro, Maki Koutaro
    • Journal Title

      The Cleft Palate-Craniofacial Journal

      Volume: 59 Issue: 2 Pages: 177-184

    • DOI

      10.1177/1055665621998181

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K10195
  • [Journal Article] Three-dimensional assessment of the pharyngeal airway in Japanese preschoolers with orofacial clefts.2020

    • Author(s)
      2)Takahashi M, Yamaguchi T, Lee MK, Suzuki Y, Adel M, Tomita D, Nakawaki T, Yoshida H, Hikita Y, Furuhata M, Tsuneoka M, Nagahama R, Marazita ML, Weinberg SM, Maki K.
    • Journal Title

      Laryngoscope

      Volume: 130 Issue: 2 Pages: 533-540

    • DOI

      10.1002/lary.27957

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09844, KAKENHI-PROJECT-17K11947
  • [Journal Article] A three-dimensional analysis of primary failure of eruption in humans and mice.2020

    • Author(s)
      5)Tokavanich N, Gupta A, Nagata M, Takahashi A, Matsushita Y, Yatabe M, Ruellas A, Cevidanes L, Maki K, Yamaguchi T, Ono N, Ono W.
    • Journal Title

      Oral Dis

      Volume: 26 Issue: 2 Pages: 391-400

    • DOI

      10.1111/odi.13249

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09844, KAKENHI-PROJECT-19K19236, KAKENHI-PROJECT-17K11947
  • [Journal Article] Three-dimensional evaluation of mandibular volume in patients with cleft lip and palate during the deciduous dentition period.2020

    • Author(s)
      Shrestha A, Takahashi M, Yamaguchi T, Adel M, Furuhata M, Hikita Y, Yoshida H, Nakawaki T, Maki K.
    • Journal Title

      Angle Orthod

      Volume: 90 Issue: 1 Pages: 85-991

    • DOI

      10.2319/112618-831.1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11947, KAKENHI-PROJECT-19K19302, KAKENHI-PROJECT-18K09844
  • [Journal Article] Autocrine regulation of mesenchymal progenitor cell fates orchestrates tooth eruption.2019

    • Author(s)
      Takahashi A, Nagata M, Gupta A, Matsushita Y, Yamaguchi T, Mizuhashi K, Maki K, Ruellas AC, Cevidanes LS, Kronenberg HM, Ono N, Ono W.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 116 Issue: 2 Pages: 575-58

    • DOI

      10.1073/pnas.1810200115

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11947
  • [Journal Article] Orthognathic surgery induces genomewide changes longitudinally in DNA methylation in saliva2018

    • Author(s)
      Yamaguchi Tetsutaro、Hosomichi Kazuyoshi、Takahashi Masahiro、Haga Shugo、Nakawaki Takatoshi、Hikita Yu、Maki Koutaro、Tajima Atsushi
    • Journal Title

      Oral Diseases

      Volume: 25 Issue: 2 Pages: 508-514

    • DOI

      10.1111/odi.12998

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-17K19804, KAKENHI-PROJECT-17K11947
  • [Journal Article] Interferon regulatory factor 6 variants affect nasolabial morphology in East Asian populations2018

    • Author(s)
      Tomita Daisuke、Yamaguchi Tetsutaro、Nakawaki Takatoshi、Hikita Yu、Adel Mohamed、Kim Yong-Il、Haga Shugo、Takahashi Masahiro、Kawaguchi Akira、Isa Mutsumi、Park Soo-Byung、Ishida Hajime、Maki Koutaro、Kimura Ryosuke
    • Journal Title

      Archives of Oral Biology

      Volume: 85 Pages: 142-147

    • DOI

      10.1016/j.archoralbio.2017.10.005

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H01752, KAKENHI-PROJECT-16K15843
  • [Journal Article] Exploration of genetic factors determining cleft side in a pair of monozygotic twins with mirror-image cleft lip and palate using whole-genome sequencing and comparison of craniofacial morphology2018

    • Author(s)
      Takahashi Masahiro、Hosomichi Kazuyoshi、Yamaguchi Tetsutaro、Nagahama Ryo、Yoshida Hiroshi、Marazita Mary L.、Weinberg Seth M.、Maki Koutaro、Tajima Atsushi
    • Journal Title

      Archives of Oral Biology

      Volume: 96 Pages: 33-38

    • DOI

      10.1016/j.archoralbio.2018.08.009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-17K19804, KAKENHI-PROJECT-16K20654
  • [Journal Article] Whole-genome sequencing in a pair of monozygotic twins with discordant cleft lip and palate subtypes2018

    • Author(s)
      Takahashi Masahiro、Hosomichi Kazuyoshi、Yamaguchi Tetsutaro、Nagahama Ryo、Yoshida Hiroshi、Maki Koutaro、Marazita Mary L.、Weinberg Seth M.、Tajima Atsushi
    • Journal Title

      Oral Diseases

      Volume: 24 Issue: 7 Pages: 1303-1309

    • DOI

      10.1111/odi.12910

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-17K19804, KAKENHI-PROJECT-16K20654
  • [Journal Article] Comprehensive genetic exploration of selective tooth agenesis of mandibular incisors by exome sequencing2017

    • Author(s)
      Yamaguchi T, Hosomichi K, Yano K, Kim Y, Nakaoka H, Kimura R, Otsuka H, Nonaka N, Haga S, Takahashi M, Shirota T, Kikkawa Y, Yamada A, Kamijo R, Park SB, Nakamura M, Maki K, Inoue I
    • Journal Title

      Hum Genome Variation

      Volume: 印刷中 Issue: 1 Pages: 17005-17005

    • DOI

      10.1038/hgv.2017.5

    • NAID

      120006891152

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-15H02373, KAKENHI-PROJECT-15H05016, KAKENHI-PROJECT-26430195, KAKENHI-PROJECT-15K20367, KAKENHI-PROJECT-15K11051, KAKENHI-PROJECT-16K15782, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17K19804, KAKENHI-PROJECT-17K17089, KAKENHI-PROJECT-25251043, KAKENHI-PROJECT-16K15843
  • [Journal Article] Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals2017

    • Author(s)
      Takahashi M, Hosomichi K, Yamaguchi T, Yano K, Funatsu T, Adel M, Haga S, Maki K, Tajima A
    • Journal Title

      Hum Genome Variation

      Volume: 印刷中 Issue: 1 Pages: 16046-16046

    • DOI

      10.1038/hgv.2016.46

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06502, KAKENHI-PROJECT-15H04320, KAKENHI-PROJECT-26430195, KAKENHI-PROJECT-16K15843
  • [Journal Article] Contribution of FGFR1 Variants to Craniofacial Variations in East Asians2017

    • Author(s)
      Adel Mohamed、Yamaguchi Tetsutaro、Tomita Daisuke、Nakawaki Takatoshi、Kim Yong-Il、Hikita Yu、Haga Shugo、Takahashi Masahiro、Nadim Mohamed A.、Kawaguchi Akira、Isa Mutsumi、El-Kenany Walid H.、El-Kadi Abbadi A.、Park Soo-Byung、Ishida Hajime、Maki Koutaro、Kimura Ryosuke
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 1 Pages: e0170645-e0170645

    • DOI

      10.1371/journal.pone.0170645

    • NAID

      120006891154

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H01752, KAKENHI-PROJECT-16K15843
  • [Journal Article] 口腔顎顔面領域に存在する神経堤由来細胞の成体における分布と細胞分化能ー新しい骨再生療法の提案ー2015

    • Author(s)
      高橋正皓
    • Journal Title

      口腔組織培養学会誌

      Volume: 24 Pages: 1-8

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26893273
  • [Presentation] Three-dimensional assessment of the pharyngeal airway in Down syndrome during the mixed dentition period2022

    • Author(s)
      Takizawa Hideomi, Takahashi Masahiro, Yoshida Hiroshi, Yamaguchi Tetsutaro, Maki Kouraro
    • Organizer
      14th International cleft congress CLEFT 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K10195
  • [Presentation] 乳歯列期の唇顎口蓋裂における下顎骨体積および顎顔面形態の三次元的解析2019

    • Author(s)
      高橋正皓、Abhishekhi Shrestha、山口徹太郎、降旗真由、中脇貴俊、冨田大介、吉田寛、槇宏太郎
    • Organizer
      第43回 日本口蓋裂学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-18K09844
  • [Presentation] 唇顎口蓋裂患児における翼突上顎部および頬骨の3次元的形態評価2019

    • Author(s)
      高橋正皓、降旗真由、山口徹太郎、Abhishekhi Shrestha、冨田大介、槇宏太郎
    • Organizer
      第29回 日本顎変形症学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-18K09844
  • [Presentation] 乳歯列期の唇顎口蓋裂における下顎骨体積および顎顔面形態の三次元的解析2019

    • Author(s)
      高橋正皓、Abhishekhi Shrestha、山口徹太郎、降旗真由、中脇貴俊、冨田大介、吉田寛、槇宏太郎
    • Organizer
      第43回日本口蓋裂学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-19K19302
  • [Presentation] 乳歯列期における唇顎口蓋裂の裂型別の下顎骨体積および顎顔面形態の比較2019

    • Author(s)
      高橋正皓、Abhishekhi Shrestha、山口徹太郎、降旗真由、疋田悠、中脇貴俊、吉田寛、槇宏太郎
    • Organizer
      第78回日本矯正歯科学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K19302
  • [Presentation] 顎顔面発育にFurlow法及びTwo-flap変法が及ぼす影響東京都その比較2019

    • Author(s)
      吉田寛、高橋正皓、山口徹太郎、槇宏太郎
    • Organizer
      第43回 日本口蓋裂学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-18K09844
  • [Presentation] 唇顎口蓋裂患児における翼突上顎部および頬骨の3次元的形態評価2019

    • Author(s)
      高橋正皓、降旗真由、山口徹太郎、Abhishekhi Shrestha、冨田大介、槇宏太郎
    • Organizer
      第29回日本顎変形症学会総会、学術集会
    • Data Source
      KAKENHI-PROJECT-19K19302
  • [Presentation] 非症候性唇顎口蓋裂を伴う一卵性双生児不一致症例における全ゲノムシーケンス解析2018

    • Author(s)
      高橋正皓、山口徹太郎、細道一善、長濱諒、吉田寛、田嶋敦、槇宏太郎
    • Organizer
      第77回日本矯正歯科学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K20654
  • [Presentation] 裂型が異なる唇顎口蓋裂の一卵性双生児不一致症例における全ゲノムシーケンス解析2018

    • Author(s)
      高橋正皓、山口徹太郎、細道一善、長濱諒、田嶋敦、槇宏太郎
    • Organizer
      第42回日本口蓋裂学会総会、学術集会
    • Data Source
      KAKENHI-PROJECT-16K20654
  • [Presentation] 裂型が異なる唇顎口蓋裂の一卵性双生児不一致症例における全ゲノムシーケンス解析2018

    • Author(s)
      高橋正皓、山口徹太郎、細道一善、長濱諒、田嶋敦、槇宏太郎
    • Organizer
      日本口蓋裂学会
    • Data Source
      KAKENHI-PROJECT-16K20654
  • [Presentation] Williams症候群の5歳から24歳の治療経過の一例2017

    • Author(s)
      山口徹太郎、代田達夫、芳賀秀郷、中島美里、降旗真由、高橋正皓、長濱諒、相原のぞみ、槇宏太郎
    • Organizer
      第27回日本顎変形症学会
    • Data Source
      KAKENHI-PROJECT-16K15843
  • [Presentation] 口唇口蓋裂患者の骨成熟度評価のための統計的形状解析2017

    • Author(s)
      山口徹太郎、芳賀秀郷、中島美里、降旗真由、高橋正皓、長濱諒、相原のぞみ、槇宏太郎
    • Organizer
      第27回日本顎変形症学会
    • Data Source
      KAKENHI-PROJECT-16K15843
  • [Presentation] 成体マウス顎下腺から分離した神経堤由来細胞の解析2014

    • Author(s)
      高橋正皓、須澤徹夫、山田篤、山口徹太郎、槇宏太郎、上條竜太郎
    • Organizer
      第51回日本口腔組織培養学会学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2014-11-15
    • Data Source
      KAKENHI-PROJECT-26893273
  • 1.  Yamaguchi Tetsutaro (40384193)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 10 results
  • 2.  Maki Koutaro (80219295)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  芳賀 秀郷 (00736655)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  中脇 貴俊 (90783522)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  上條 竜太郎 (70233939)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  須澤 徹夫 (60271285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  冨田 大介 (40805842)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  吉田 寛 (20823074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  HOSOMICHI Kazuyoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 10.  KIMURA Ryousuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 11.  槙 宏太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results

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