Nii Takenobu 二井偉暢

… Alternative Names

二井偉暢ニイタケノブ

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Researcher Number	10743990
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 助教
Affiliation (based on the past Project Information) *help	2025: 九州大学, 医学研究院, 助教 2020 – 2022: 九州大学, 医学研究院, 助教 2018 – 2019: 九州大学, 先端融合医療創成センター, 特任講師 2015: 九州大学, 生体防御医学研究所, 学術研究員
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related / Basic Section 48010:Anatomy-related / Basic Section 50010:Tumor biology-related / 0901:Oncology and related fields / Hematology
Keywords	Principal Investigator 着床 / 骨髄微小環境 / iPS細胞 / AML / ヒトiPS細胞 / 初期胚発生 / 多能性変遷 / MSC / モデルマウス / 急性骨髄性白血病 … More / マウスモデル / 白血病 / 幹細胞 / 微小環境 / テラトーマ / 遺伝子導入 / 造血幹細胞 / ヒトES細胞 Less

着床前後の胚培養技術を用いた体軸形成機構の解明Principal Investigator
- Principal Investigator
  
  二井偉暢
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Kyushu University
エピブラストの形態変化と多能性変遷機構の解明Principal Investigator
- Principal Investigator
  
  二井偉暢
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Kyushu University
Establishment of AML mouse model using human iPSCPrincipal Investigator
- Principal Investigator
  
  Nii Takenobu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyushu University
ヒトiPS細胞由来異所性ヒト骨髄を用いた急性骨髄性白血病幹細胞維持機構の解明Principal Investigator
- Principal Investigator
  
  二井偉暢
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kyushu University
転写因子を用いた高効率in vivo 造血幹細胞分化誘導法Principal Investigator
- Principal Investigator
  
  二井偉暢
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University

All 2022 2021 2020 2019 2015

All Journal Article Presentation Patent

[Journal Article] The Bioactive Peptide SL-13R Expands Human Umbilical Cord Blood Hematopoietic Stem and Progenitor Cells In Vitro2021
- Author(s)
  Nii Takenobu、Konno Katsuhiro、Matsumoto Masaki、Bhukhai Kanit、Borwornpinyo Suparerk、Sakai Kazuhiro、Hongeng Suradej、Sugiyama Daisuke
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 7 Pages: 1995-1995
- DOI
  10.3390/molecules26071995
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16774, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-20K21386
[Journal Article] Establishing a translational research network in the Asia-Pacific Region through Industry-Academia-Government Collaboration: The Japan Medical Innovation Program2020
- Author(s)
  NII Takenobu、SWAIN Anthony、MINE Yuichi、TAKAI-YUMINE Ayako、SUGIYAMA Daisuke
- Journal Title
  
  Translational and Regulatory Sciences
  
  Volume: 2 Issue: 2 Pages: 42-46
- DOI
  10.33611/trs.2020-004
- NAID
  130007889735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16774
[Journal Article] Establishment of a Translational Science and Medicine Training Program in Japan2020
- Author(s)
  NII Takenobu、SITTAMPALAM Sitta G.、MINE Yuichi、SUGIYAMA Daisuke
- Journal Title
  
  Translational and Regulatory Sciences
  
  Volume: 2 Issue: 2 Pages: 36-41
- DOI
  10.33611/trs.2020-005
- NAID
  130007889753
- ISSN
  2434-4974
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16774
[Journal Article] Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.2019
- Author(s)
  Ishizawa J, Zarabi SF, Davis RE, Halgas O, Nii T, Jitkova Y, Zhao R, St-Germain J, Heese LE, Egan G, Ruvolo VR, Barghout SH, Nishida Y, Hurren R, Ma W, Gronda M, Link T, Wong K, Mabanglo M, Kojima K, Andreeff M
- Journal Title
  
  Cancer Cell
  
  Volume: 35 Issue: 5 Pages: 721-737
- DOI
  10.1016/j.ccell.2019.03.014
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-19K16774
[Journal Article] Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia2019
- Author(s)
  Takenobu Nii, Varun Prabhu, Vivian Ruvolo, Neel Madhukar, Ran Zhao, Hong Mu, Lauren Heese, Yuki Nishida, Kensuke Kojima, Mathew Garnett, Ultan McDermott, Cyril Benes, Neil Charter, Sean Deacon, Olivier Elemento, Josh Allen, Wolfgang Oster, Martin Stogniew, Jo Ishizawa, Michael Andreeff.
- Journal Title
  
  Leukemia
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H06163
[Journal Article] ipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia2019
- Author(s)
  Nii T, Prabhu VV, Ruvolo V, Madhukar N, Zhao R, Mu H, Heese L, Nishida Y, Kojima K, Garnett MJ, McDermott U, Benes CH, Charter N, Deacon S, Elemento O, Allen JE, Oster W, Stogniew M, Ishizawa J, Andreeff M.
- Journal Title
  
  Leukemia
  
  Volume: 33 Issue: 12 Pages: 2805-2816
- DOI
  10.1038/s41375-019-0491-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09928, KAKENHI-PROJECT-19K16774
[Journal Article] mproved hematopoietic differentiation of primate embryonic stem cells by inhibition of the PI3K-AKT pathway under defined conditions.2015
- Author(s)
  Takenobu Nii, Tomotoshi Marumoto, Hiroshi Kohara, Saori Yamaguchi, Hirotaka Kawano, Erika Sasaki, Yoshie Kametani, Kenzaburo Tani
- Journal Title
  
  Exp Hematol
  
  Volume: 43 Issue: 10 Pages: 901-911
- DOI
  10.1016/j.exphem.2015.06.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430095, KAKENHI-PROJECT-15K19553
[Patent] 胚の培養法2022
- Inventor(s)
  目野主税、二井偉暢
- Industrial Property Rights Holder
  九州大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-047454
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K06810
[Presentation] BIOACTIVE PEPTIDE SL-13R EXPANDS HUMAN UMBILICAL CORD BLOOD HEMATOPOIETIC STEM CELLS2019
- Author(s)
  Takenobu Nii, Katsuhiro Konno, Mami Shigeto, Ayako Kaneyuki, Motoko Sumasu, Toshiyuki Owaki, Daisuke Sugiyama.
- Organizer
  International Society for Stem Cell Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16774
[Presentation] Single-cell-state culture of human pluripotent stem cells increases transfection efficiency.2015
- Author(s)
  Takenobu Nii, Hiroshi Kohara, Tomotoshi Marumoto, Tetsushi Sakuma, Takashi Yamamoto, Kenzaburo Tani
- Organizer
  日本遺伝子治療学会
- Place of Presentation
  大阪国際会議場（大阪）
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-15K19553
[Presentation] Single-cell-state culture of human pluripotent stem cells increases transfection efficiency.2015
- Author(s)
  Takenobu Nii, Hiroshi Kohara, Tomotoshi Marumoto, Tetsushi Sakuma, Takashi Yamamoto, Kenzaburo Tani
- Organizer
  The American Society of Hematology
- Place of Presentation
  Orlando（米国）
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15K19553

1. 小島研介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 亀谷美恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 佐々木えりか

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nii Takenobu 二井 偉暢

二井 偉暢 ニイ タケノブ

Research Projects

Research Products

Co-Researchers

着床前後の胚培養技術を用いた体軸形成機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エピブラストの形態変化と多能性変遷機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of AML mouse model using human iPSCPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒトiPS細胞由来異所性ヒト骨髄を用いた急性骨髄性白血病幹細胞維持機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

転写因子を用いた高効率in vivo 造血幹細胞分化誘導法Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Bioactive Peptide SL-13R Expands Human Umbilical Cord Blood Hematopoietic Stem and Progenitor Cells In Vitro2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishing a translational research network in the Asia-Pacific Region through Industry-Academia-Government Collaboration: The Japan Medical Innovation Program2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Establishment of a Translational Science and Medicine Training Program in Japan2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia2019

Author(s)

Journal Title

Data Source

[Journal Article] ipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] mproved hematopoietic differentiation of primate embryonic stem cells by inhibition of the PI3K-AKT pathway under defined conditions.2015

Author(s)

Journal Title

DOI

Data Source

[Patent] 胚の培養法2022

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

Nii Takenobu 二井偉暢

二井偉暢ニイタケノブ