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Moro Kazuki  諸 和樹

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諸 和樹  モロ カズキ

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Researcher Number 10745566
Other IDs
Affiliation (Current) 2025: 新潟大学, 医歯学総合病院, 助教
Affiliation (based on the past Project Information) *help 2022 – 2024: 新潟大学, 医歯学総合病院, 助教
2021: 新潟大学, 医歯学総合病院, 特任助教
2019 – 2020: 新潟大学, 医歯学総合病院, 専任助教
2015 – 2017: 新潟大学, 医歯学総合病院, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 55010:General surgery and pediatric surgery-related
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / General surgery
Keywords
Principal Investigator
アポトーシス / 乳癌 / スフィンゴ脂質レオスタット / 脂質メディエーター分子 / 転移リンパ節 / 脂質メディエーター / 免疫微小環境 / ミンクル受容体 / グリコシルセラミド / 化学療法 … More / マクロファージ / RNAシークエンス / リピドミクス解析 / スフィンゴシン1リン酸 / セラミド / グルコシルセラミド … More
Except Principal Investigator
脂質メディエーター / 乳癌 / トリプルネガティブ / HER2 / 免疫組織化学 / 人工知能 / スフィンゴシン-1-リン酸 / 乳がん / 免疫チェックポイント阻害薬 / 相同組換え修復欠損 / 変異シグネチャー / Whole slide imaging / がん遺伝子パネル検査 / ERBB2 / 胃癌 / TP53 / パスウェイ解析 / 遺伝子異常 / 化学療法 / 胆囊癌 / Heterogeneity / 胆嚢癌 / 生存解析 / 外科切除 / FISH / 抗HER2療法 / HER2陽性胆嚢癌 / 高次元データ解析システム / ゲノム / 高次元データ解析 / マイクロサテライト不安定性 / 腫瘍変異負荷 / ゲノム高次元データ解析 / 深層学習 / 消化器癌 / セラミド / 膵島移植 / 糖尿病 / 移植免疫 / 臓器移植 / 細胞移植 / 免疫微小環境 / SphK1 / pSphK1 / S1P / 膵癌 / スフィンゴシン‐1-リン酸 / 治療 / 腫瘍免疫微小環境 / スフィンゴシン-1-リン酸 / RBP / RTP / 末梢静脈栄養 / Rapid turnover protein / インスリン抵抗性 / タンパク代謝 / 低脂肪経腸栄養剤 / 乳び胸 / 経腸栄養 / CRP / 術後回復 / 脂肪乳剤 / 静脈栄養 / カルニチン Less
  • Research Projects

    (11 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (33 People)
  •  乳癌の腫瘍進展におけるスフィンゴ脂質レオスタットの臨床的意義の解明Principal Investigator

    • Principal Investigator
      諸 和樹
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Niigata University
  •  不均一性の強い胃癌のHER2関連遺伝子異常を高精度に同定可能とする人工知能の開発

    • Principal Investigator
      臼井 賢司
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Niigata University
  •  トリプルネガティブ乳癌における変異シグネチャー解析の臨床病理学的意義の解明

    • Principal Investigator
      土田 純子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Niigata University
  •  Development of Artificial Intelligence by Deep Learning Based on Genomic High-Dimensional Data Analysis System for Gastrointestinal Cancer

    • Principal Investigator
      WAKAI TOSHIFUMI
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Comprehensive cancer-related pathway analysis of genetic abnormalities in HER2-positive gallbladder cancer and their clinical significance

    • Principal Investigator
      Sakata Jun
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  トリプルネガティブ乳癌におけるTP53と脂質分子の相補的な細胞制御機構の解明

    • Principal Investigator
      永橋 昌幸
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Hyogo Medical University
  •  Clinical Significance of Lipid Mediator in the tumor Microenvironment of Pancreatic Adenocarcinoma

    • Principal Investigator
      TAKIZAWA KAZUYASU
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Extend islet graft survival in pancreatic islet transplantation by applying the immunoregulatory mechanism of ceramide

    • Principal Investigator
      Kobayashi Takashi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Niigata University
  •  Clinical significance of glycosylceramide in the immune microenvironment of breast cancerPrincipal Investigator

    • Principal Investigator
      Moro Kazuki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Niigata University
  •  The role of lipid mediator in the tumor immune microenvironment of breast cancer and its therapeutic application

    • Principal Investigator
      Nagahashi Masayuki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Hyogo Medical University
      Niigata University
  •  Serum carnitine kinetics by administration of fat emulsion at the perioperative period and effect of intravenous administration of L-carnitine

    • Principal Investigator
      Koyama Yu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Niigata University

All 2023 2022 2021 2020 2017 2016

All Journal Article Presentation

  • [Journal Article] Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients2023

    • Author(s)
      Nagahashi M, Ling Y, Toshikawa C, Hayashida T, Kitagawa Y, Futamura M, Kuwayama T, Nakamura S, Yamauchi H, Yamauchi T, Kaneko K, Kanbayashi C, Sato N, Tsuchida J, Moro K, Nakajima M, Shimada Y, Ichikawa H, Lyle S, Miyoshi Y, Takabe K, Okuda S, Wakai T.
    • Journal Title

      Breast Cancer

      Volume: - Issue: 4 Pages: 584-595

    • DOI

      10.1007/s12282-023-01449-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19522, KAKENHI-PROJECT-21K17850
  • [Journal Article] Clinical Significance of Phosphorylated Sphingosine Kinase 1 Expression in Pancreatic Ductal Adenocarcinoma2023

    • Author(s)
      Nagaro H, Ichikawa H, Takizawa K, Nagahashi M, Abe S, Hirose Y, Moro K, Miura K, Nakano M, Shimada Y, Sakata J, Wakai T
    • Journal Title

      Anticancer Res

      Volume: 43 Issue: 9 Pages: 3969-3977

    • DOI

      10.21873/anticanres.16584

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Journal Article] Plasma Sphingosine-1-Phosphate Levels Are Associated with Progression of Estrogen Receptor-Positive Breast Cancer2021

    • Author(s)
      Ikarashi Mayuko、Tsuchida Junko、Nagahashi Masayuki、Takeuchi Shiho、Moro Kazuki、Toshikawa Chie、Abe Shun、Ichikawa Hiroshi、Shimada Yoshifumi、Sakata Jun、Koyama Yu、Sato Nobuaki、Hait Nitai C.、Ling Yiwei、Okuda Shujiro、Takabe Kazuaki、Wakai Toshifumi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 24 Pages: 13367-13367

    • DOI

      10.3390/ijms222413367

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03714, KAKENHI-PROJECT-21K17850
  • [Journal Article] Intravenous Carnitine Administration in Addition to Parenteral Nutrition with Lipid Emulsion may Decrease the Inflammatory Reaction in Postoperative Surgical Patients.2017

    • Author(s)
      KoyamaY, Moro K, Nakano M, Miura K, Nagahashi M, Kosugi S-I, Tsuchida J, Ikarashi M, Nakajima M, Ichikawa H, Hanyu T, Shimada Y, Jun Sakata J, Kameyama H, Kobayashi T, Wakai T.
    • Journal Title

      Journal of Clinical Medicine Research

      Volume: 9 Issue: 10 Pages: 831-837

    • DOI

      10.14740/jocmr3113w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10047
  • [Journal Article] Low fat-containing elemental formula is effective for postoperative recovery and potentially useful for preventing chyle leak during postoperative early enteral nutrition after esophagectomy.2016

    • Author(s)
      Moro K, Koyama Y, Kosugi SI, Ishikawa T, Ichikawa H, Hanyu T, Miura K, Nagahashi M, Nakajima M, Tatsuda K, Tsuchida J, Toshikawa C, Ikarashi M, Shimada Y, Sakata J, Kobayashi T, Kameyama H, Wakai T
    • Journal Title

      Clinical Nutrition

      Volume: 35 Issue: 6 Pages: 1423-1428

    • DOI

      10.1016/j.clnu.2016.03.018

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10047, KAKENHI-PROJECT-16K10491
  • [Presentation] 乳癌モデルマウスにおいてグルコシルセラミド経口投与は腫瘍進展を抑制した2023

    • Author(s)
      諸 和樹、利川千絵、安部 舜、内田 遥、成瀬香菜、小幡泰生、 大路麻巳子、土田純子、宗岡悠介、廣瀬雄己、三浦宏平、田島陽介、中野麻恵、市川 寛、島田能史、永橋昌幸、坂田 純、小林 隆、小山 諭、若井俊文
    • Organizer
      第123回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-20K17578
  • [Presentation] シンポジウム4(SY-04-2)固形癌におけるゲノム医療:腫瘍外科と融合したPrecision Cancer Medicine2023

    • Author(s)
      若井俊文,島田能史,中野麻恵,田島陽介,中野雅人,宗岡悠介,臼井賢司,加納陽介,市川 寛,石川 卓,諸 和樹,土田純子,安部 舜,安藤拓也,石川博補,廣瀬雄己,三浦宏平,滝沢一泰,坂田 純,小林 隆
    • Organizer
      第123回日本外科学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02998
  • [Presentation] IMPROVING ENDOCRINE FUNCTION OF TRANSPLANTED ISLETS BY CERAMIDE IN RAT ISLET AUTOTRANSPLANT MODEL2022

    • Author(s)
      Takashi Kobayashi, Yoshiaki Kinoshita, Yoshiaki Takahashi, Toshiyuki Ohyama, Yuhki Arai, Yu Sugai, Yu Hamasaki, Kohei Miura, Hirosuke Ishikawa, Kazuki Moro, Jun Sakata, Toshifumi Wakai
    • Organizer
      35th the International Symposium on Paediatric Surgical Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21628
  • [Presentation] 乳癌患者における血清グルコシルセラミドの臨床的意義2021

    • Author(s)
      諸 和樹、永橋昌幸、内田 遙、小幡泰生、遠藤麻巳子、土田純子、利川千絵、五十嵐麻由子、小山 諭、若井俊文
    • Organizer
      第29回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K17578
  • [Presentation] 肥満状態下の乳癌転移におけるスフィンゴシン-1-リン酸の役割2021

    • Author(s)
      永橋 昌幸,土田 純子,諸 和樹,長谷川 遙,小幡 泰生,遠藤 麻巳子, 利川 千絵,五十嵐 麻由子,小山 諭,高部 和明,若井 俊文
    • Organizer
      第29回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03714
  • [Presentation] Involvement of sphingosine-1-phosphate in tumor immune microenvironment of breast cancer patients2020

    • Author(s)
      Junko Tsuchida, Masayuki Nagahashi, Mayuko Ikarashi, Kazuki Moro, Chie Toshikawa, Hiroshi Ichikawa, Yoshifumi Shimada, Kazuaki Takabe, Toshifumi Wakai
    • Organizer
      The 15th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03714
  • [Presentation] 慢性炎症による癌の増殖・転移を促進する脂質メディエーター分子機構2020

    • Author(s)
      永橋 昌幸,土田 純子,油座 築,諸 和樹,根本 万里子,廣瀬 雄己,利川 千絵,五十嵐 麻由子,三浦 宏平,市川 寛,羽入 隆晃,滝沢 一泰,中島 真人,島田 能史,小林 隆,坂田 純,石川 卓,亀山 仁史,若井 俊文
    • Organizer
      第120回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19H03714
  • [Presentation] Validity of adding intravenous carnitine to parenteral nutrition with lipid emulsion for deceasing inflammatory reaction of postoperative surgical patients.2017

    • Author(s)
      Koyama Y, Moro K, Miura K, Nagahashi M, Kosugi S-I, Tsuchida J, Ikarashi M, Nakajima M, Ichikawa H, Shimada Y, Kameyama H, Kobayashi T, Wakai T
    • Organizer
      39th ESPEN
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10047
  • [Presentation] 周術期末梢静脈栄養:脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果2017

    • Author(s)
      諸 和樹、小山 諭、永橋昌幸、三浦宏平、土田純子、中島真人、若井俊文1
    • Organizer
      第54回日本外科代謝栄養学会
    • Place of Presentation
      朱鷺メッセ 新潟コンベンションセンター(新潟県新潟市)
    • Year and Date
      2017-07-06
    • Data Source
      KAKENHI-PROJECT-15K10047
  • [Presentation] 周術期末梢静脈栄養 脂肪乳剤投与におけるカルニチン併用による炎症反応の軽減効果.2017

    • Author(s)
      諸 和樹, 小山 諭, 永橋 昌幸, 三浦 宏平, 土田 純子, 中島 真人, 若井 俊文.
    • Organizer
      第54回日本外科代謝栄養学会
    • Data Source
      KAKENHI-PROJECT-15K10047
  • [Presentation] 周術期末梢静脈栄養における脂肪乳剤とカルニチン投与の検討2016

    • Author(s)
      小山 諭、諸 和樹、永橋昌幸、三浦宏平、辰田久美子、土田純子、中島真人、若井俊文
    • Organizer
      第53回日本外科代謝栄養学会
    • Place of Presentation
      伊藤国際学術研究センター(東京都文京区)
    • Year and Date
      2016-07-07
    • Data Source
      KAKENHI-PROJECT-15K10047
  • 1.  Nagahashi Masayuki (30743918)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 12 results
  • 2.  WAKAI TOSHIFUMI (50372470)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 12 results
  • 3.  Sakata Jun (70447605)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 4.  三浦 宏平 (70733658)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 5.  奥田 修二郎 (00512310)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 6.  島田 能史 (20706460)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 7.  土田 純子 (90769415)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 8.  市川 寛 (50721875)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 9.  Kobayashi Takashi (40464010)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 10.  TAKIZAWA KAZUYASU (30706437)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  阿部 学 (10334674)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 12.  油座 築 (00745565)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  廣瀬 雄己 (10737365)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  松田 康伸 (40334669)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  宗岡 悠介 (00769391)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 16.  須貝 美佳 (10772030)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  Koyama Yu (10323966)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 18.  KOMATSU Masaaki (90356254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  小杉 伸一 (90401736)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 20.  崎村 建司 (40162325)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  三好 康雄 (50283784)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  五十嵐 道弘 (50193173)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 23.  長櫓 宏規 (90888033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  木下 義晶 (80345529)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  石川 博補 (80769399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  臼井 賢司 (70769413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  梅津 哉 (50251799)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  加納 陽介 (90745580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  遠藤 麻巳子 (20915227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  凌 一葦 (70804540)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  利川 千絵 (80745563)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  内田 遥 (80962795)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  小幡 泰生 (00978702)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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