Yakabe Mitsutaka 矢可部満隆

… Alternative Names

YAKABE Mitsutaka 矢可部満隆

Less

Researcher Number	10747265
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京大学, 医学部附属病院, 助教 2015 – 2016: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / General internal medicine(including psychosomatic medicine) Except Principal Investigator Basic Section 52010:General internal medicine-related / General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator 補中益気湯 / 漢方薬 / 廃用性筋萎縮 / サルコペニア / 後肢懸垂マウス / リハビリテーション / AMPK / 筋萎縮関連因子 / 後肢懸垂モデルマウス / 後肢懸垂モデル … More / ビタミンD / HMB / 筋萎縮 / 炎症 … More Except Principal Investigator サルコペニア / 性ホルモン / 血管老化 / 慢性炎症 / アンドロゲン受容体 / 液性因子 / 連関作用 / ホルモン / 筋代謝 / 血管炎症 / 筋分解 / 廃用性筋萎縮 / アンドロゲン / ブレンド効果 / Ginsenoseide Rb1 / 虚証 / エストロゲン受容体 / Paeoniflorin / フレイル / 血管石灰化 / Ginsenoside Rb1 / 気虚 Less

Elucidation of the inflammaging-linking relationship between muscle and vascular aging
- Principal Investigator
  
  秋下雅弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokyo
「リハ漢方」の確立を目指した、リハビリテーションにおける漢方薬の効果の基礎的検討Principal Investigator
- Principal Investigator
  
  矢可部満隆
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokyo
速筋特異的アンドロゲン作用を介した加齢性サルコペニアおよび筋骨連関制御機構の解明
- Principal Investigator
  
  小川純人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokyo
Suggestion of therapeutic strategies of sarcopenia by unraveling mechanism through anti-inflammatory actions of androgen
- Principal Investigator
  
  Son Bo-Kyung
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokyo
Effects of herbal medicines on the muscle atrophy of sarcopenic mice.Principal Investigator
- Principal Investigator
  
  Yakabe Mitsutaka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokyo
Development of frailty-preventing Kampo and personalization
- Principal Investigator
  
  AKISHITA MASAHIRO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  The University of Tokyo
Possible teatment for sarcopenia by inhibition of inflammationPrincipal Investigator
- Principal Investigator
  
  YAKABE Mitsutaka
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Exercise-induced vitamin D receptor and androgen receptor mediate inhibition of IL-6 and STAT3 in muscle.2024
- Author(s)
  Hashimoto S, Hosoi T, Yakabe M, Matsumoto S, Hashimoto M, Akishita M, Ogawa S
- Journal Title
  
  Biochem Biophys Rep
  
  Volume: 23 Pages: 101621-101621
- DOI
  10.1016/j.bbrep.2023.101621
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07465
[Journal Article] Sarcopenia phenotype and impaired muscle function in male mice with fast-twitch muscle-specific knockout of the androgen receptor2023
- Author(s)
  Hosoi Tatsuya、Yakabe Mitsutaka、Sasakawa Hiroko、Sasako Takayoshi、Ueki Kohjiro、Kato Shigeaki、Tokuoka Suzumi M.、Oda Yoshiya、Abe Masahiro、Matsumoto Toshio、Akishita Masahiro、Ogawa Sumito
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 4
- DOI
  10.1073/pnas.2218032120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07465, KAKENHI-PROJECT-22H03104
[Journal Article] Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro2022
- Author(s)
  Mitsutaka Yakabe, Tatsuya Hosoi, Hiroko Sasakawa, Masahiro Akishita, Sumito Ogawa
- Journal Title
  
  BMC Complementary Medicine and Therapies
  
  Volume: 22 Issue: 1 Pages: 341-341
- DOI
  10.1186/s12906-022-03812-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07440
[Journal Article] Inhibition of interleukin-6 decreases atrogene expression and ameliorates tail suspension-induced skeletal muscle atrophy2018
- Author(s)
  Yakabe M, Ogawa S, Ota H, Iijima K, Eto M, Ouchi Y, Akishita M
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 1 Pages: e0191318-e0191318
- DOI
  10.1371/journal.pone.0191318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15407, KAKENHI-PROJECT-15H04800
[Journal Article] Age-related sarcopenia and its pathophysiological bases2016
- Author(s)
  Sumito Ogawa, Mitsutaka Yakabe and Masahiro Akishita
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 36 Issue: 1 Pages: 17-17
- DOI
  10.1186/s41232-016-0022-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19280
[Journal Article] Beta-hydroxy-beta-methylbutyrate Inhibits Lipopolysaccharide-induced Interleukin-6 Expression by Increasing Protein Phosphatase-1α Expression.2015
- Author(s)
  Mitsutaka Yakabe, Sumito Ogawa, Hidetaka Ota, Katsuya Iijima, Masato Eto, Yasuyoshi Ouchi, Masahiro Akishita
- Journal Title
  
  RNA and Transcription
  
  Volume: 1 Pages: 1-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19280
[Presentation] 後肢懸垂モデルマウスの骨格筋萎縮に対する補中益気湯の効果の検討2019
- Author(s)
  矢可部満隆、小川純人、秋下雅弘
- Organizer
  第61回日本老年医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15383
[Presentation] 後肢懸垂モデルマウスの骨格筋萎縮に対する補中益気湯の効果の検討2019
- Author(s)
  矢可部満隆
- Organizer
  第61回日本老年医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15383
[Presentation] In vitroにおける補中益気湯の抗炎症効果、サルコペニア抑制効果の可能性の検討2017
- Author(s)
  矢可部満隆、小川純人、秋下雅弘
- Organizer
  第59回日本老年学会
- Data Source
  KAKENHI-PROJECT-16K15407
[Presentation] HMB (β-hydroxy-β-methylbutyrate) による廃用性筋萎縮回復効果の検討2015
- Author(s)
  矢可部満隆
- Organizer
  サルコペニアフレイル研究会
- Place of Presentation
  伊藤国際学術研究センター (東京都文京区)
- Year and Date
  2015-10-04
- Data Source
  KAKENHI-PROJECT-15K19280

1. OGAWA Sumito (20323579)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. Son Bo-Kyung (20625256)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. AKISHITA MASAHIRO (00261975)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 細井達矢 (70907831)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 七尾道子 (40876091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yakabe Mitsutaka 矢可部 満隆

YAKABE Mitsutaka 矢可部 満隆

Research Projects

Research Products

Co-Researchers

Elucidation of the inflammaging-linking relationship between muscle and vascular aging

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

「リハ漢方」の確立を目指した、リハビリテーションにおける漢方薬の効果の基礎的検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

速筋特異的アンドロゲン作用を介した加齢性サルコペニアおよび筋骨連関制御機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Suggestion of therapeutic strategies of sarcopenia by unraveling mechanism through anti-inflammatory actions of androgen

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of herbal medicines on the muscle atrophy of sarcopenic mice.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of frailty-preventing Kampo and personalization

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Possible teatment for sarcopenia by inhibition of inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Exercise-induced vitamin D receptor and androgen receptor mediate inhibition of IL-6 and STAT3 in muscle.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sarcopenia phenotype and impaired muscle function in male mice with fast-twitch muscle-specific knockout of the androgen receptor2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of interleukin-6 decreases atrogene expression and ameliorates tail suspension-induced skeletal muscle atrophy2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Age-related sarcopenia and its pathophysiological bases2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Beta-hydroxy-beta-methylbutyrate Inhibits Lipopolysaccharide-induced Interleukin-6 Expression by Increasing Protein Phosphatase-1α Expression.2015

Author(s)

Journal Title

Data Source

[Presentation] 後肢懸垂モデルマウスの骨格筋萎縮に対する補中益気湯の効果の検討2019

Author(s)

Organizer

Data Source

Yakabe Mitsutaka 矢可部満隆

YAKABE Mitsutaka 矢可部満隆