Kurimoto Ryota 栗本遼太

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KURIMOTO Ryota 栗本遼太

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Researcher Number	10753957
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 講師
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 大学院医歯学総合研究科, 講師 2021 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 講師 2018 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2017: 東京医科歯科大学, 大学院医歯学総合研究科, プロジェクト助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related / Tumor therapeutics Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator RNA / がん / microRNA / RNA結合タンパク質 / マイクロRNA / EMT / 白血病 / mRNA / tRNA / let-7 … More / 腫瘍抑制 / tRNA修飾酵素 / シュードウリジン / CLIP / RNA修飾 / 転写後修飾 / タンパク質翻訳 / 腫瘍 / 転写開始因子 / 肺癌 / eIF2gamma … More Except Principal Investigator 再生医学 / 炎症性疾患 / 創薬スクリーニング / 関節組織 / ヒト組織バンク Less

新規mRNA修飾酵素によるがん浸潤転移制御の解明と治療応用Principal Investigator
- Principal Investigator
  
  栗本遼太
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Institute of Science Tokyo
白血病における腫瘍抑制マイクロRNA let-7の新規制御機構の解明と治療応用Principal Investigator
- Principal Investigator
  
  栗本遼太
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Medical and Dental University
International research collaboration on inflammatory diseases and regenerative medicine by linking human tissue banks and drug discovery
- Principal Investigator
  
  淺原弘嗣
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tokyo Medical and Dental University
Elucidation of the mechanism of novel regulators of tumor suppressor microRNA let-7 and search for novel therapeutic targetsPrincipal Investigator
- Principal Investigator
  
  Kurimoto Ryota
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Medical and Dental University
Molecular mechanism of eIF2gamma in Lung cancerPrincipal Investigator
- Principal Investigator
  
  KURIMOTO Ryota
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Tokyo Medical and Dental University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] The essential role of Mkx in periodontal ligament on the metabolism of alveolar bone and cementum2024
- Author(s)
  Yagasaki Lisa、Chiba Tomoki、Kurimoto Ryota、Nakajima Mitsuyo、Iwata Takanori、Asahara Hiroshi
- Journal Title
  
  Regenerative Therapy
  
  Volume: 25 Pages: 186-193
- DOI
  10.1016/j.reth.2023.12.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07444, KAKENHI-PROJECT-22K07226, KAKENHI-PROJECT-20H05696
[Journal Article] RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs2023
- Author(s)
  Yamamoto Hiroto、Uchida Yutaro、Kurimoto Ryota、Chiba Tomoki、Matsushima Takahide、Ito Yoshiaki、Inotsume Maiko、Miyata Kohei、Watanabe Kenta、Inada Masaki、Goshima Naoki、Uchida Tokujiro、Asahara Hiroshi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 1 Pages: 102791-102791
- DOI
  10.1016/j.jbc.2022.102791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07444, KAKENHI-PROJECT-22K05490, KAKENHI-PROJECT-20H05696, KAKENHI-PROJECT-20H00574, KAKENHI-PROJECT-20H02534, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-23K24722, KAKENHI-PROJECT-22K07226
[Journal Article] One‐step generation of mice with gene editing by <i>Tol2</i> transposon‐dependent <scp>gRNA</scp> delivery2023
- Author(s)
  Inotsume Maiko、Chiba Tomoki、Matsushima Takahide、Kurimoto Ryota、Nakajima Mitsuyo、Kato Tomomi、Shishido Kana、Liu Lin、Kawakami Koichi、Asahara Hiroshi
- Journal Title
  
  FEBS Letters
  
  Volume: 597 Issue: 7 Pages: 975-984
- DOI
  10.1002/1873-3468.14605
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07444, KAKENHI-PROJECT-22K07226, KAKENHI-PROJECT-21K19403, KAKENHI-PROJECT-20H05696, KAKENHI-PROJECT-21H02463
[Journal Article] Identification of chemical compounds regulating PD‐L1 by introducing HiBiT‐tagged cells2021
- Author(s)
  Uchida Yutaro、Matsushima Takahide、Kurimoto Ryota、Chiba Tomoki、Inutani Yuki、Asahara Hiroshi
- Journal Title
  
  FEBS Letters
  
  Volume: 595 Issue: 5 Pages: 563-576
- DOI
  10.1002/1873-3468.14032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07444, KAKENHI-PROJECT-18K19603, KAKENHI-PROJECT-18K15115, KAKENHI-PROJECT-19KK0227, KAKENHI-PROJECT-19K16794, KAKENHI-PROJECT-20H05696, KAKENHI-PROJECT-17K15447
[Journal Article] Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis.2021
- Author(s)
  Ito Y, Matsuzaki T, Ayabe F, Mokuda S, Kurimoto R, Matsushima T, Tabata Y, Inotsume M, Tsutsumi H, Liu L, Shinohara M, Tanaka Y, Nakamichi R, Nishida K, Lotz MK, Asahara H.
- Journal Title
  
  Nat Commun
  
  Volume: 12 Issue: 1 Pages: 4148-4148
- DOI
  10.1038/s41467-021-24460-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16794, KAKENHI-PROJECT-19H03991, KAKENHI-PROJECT-20H05696
[Journal Article] In vitro Neo-Genesis of Tendon/Ligament-Like Tissue by Combination of Mohawk and a Three-Dimensional Cyclic Mechanical Stretch Culture System2020
- Author(s)
  Kataoka Kensuke、Kurimoto Ryota、Tsutsumi Hiroki、Chiba Tomoki、Kato Tomomi、Shishido Kana、Kato Mariko、Ito Yoshiaki、Cho Yuichiro、Hoshi Osamu、Mimata Ayako、Sakamaki Yuriko、Nakamichi Ryo、Lotz Martin K.、Naruse Keiji、Asahara Hiroshi
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 8 Pages: 307-307
- DOI
  10.3389/fcell.2020.00307
- NAID
  120006869584
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07444, KAKENHI-PROJECT-20K21896, KAKENHI-PROJECT-19K16794, KAKENHI-PROJECT-18K19603, KAKENHI-PROJECT-18K15115, KAKENHI-PROJECT-19KK0227
[Journal Article] Transcriptional, epigenetic and microRNA regulation of growth plate2020
- Author(s)
  Ryo Nakamichiab, RyotaKurimotoc, Yusuke Tabatad, Hirosi Asahara
- Journal Title
  
  Bone
  
  Volume: in press Pages: 115434-115434
- DOI
  10.1016/j.bone.2020.115434
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16794
[Journal Article] The tRNA pseudouridine synthase TruB1 regulates the maturation of let‐7 miRNA2020
- Author(s)
  Kurimoto Ryota、Chiba Tomoki、Ito Yoshiaki、Matsushima Takahide、Yano Yuki、Miyata Kohei、Yashiro Yuka、Suzuki Tsutomu、Tomita Kozo、Asahara Hiroshi
- Journal Title
  
  The EMBO Journal
  
  Volume: 39 Issue: 20
- DOI
  10.15252/embj.2020104708
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07444, KAKENHI-PROJECT-19K16794, KAKENHI-PROJECT-18H03980, KAKENHI-PROJECT-18K19603, KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-18K15115, KAKENHI-PROJECT-19KK0227, KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-17K15447
[Journal Article] Transcriptome analysis of sevoflurane exposure effects at the different brain regions.2020
- Author(s)
  Yamamoto H, Uchida Y, Chiba T, Kurimoto R, Matsushima T, Inotsume M, Ishikawa C, Li H, Shiga T, Muratani M, Uchida T, Asahara H
- Journal Title
  
  PLos One
  
  Volume: 15 Issue: 12 Pages: e0236771-e0236771
- DOI
  10.1371/journal.pone.0236771
- NAID
  120007180737
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16794, KAKENHI-PROJECT-20H05696, KAKENHI-PROJECT-20H00547, KAKENHI-PROJECT-18K19603, KAKENHI-PROJECT-19KK0227, KAKENHI-PROJECT-17K15447
[Journal Article] Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs2019
- Author(s)
  Uchida Yutaro、Chiba Tomoki、Kurimoto Ryota、Asahara Hiroshi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 166 Issue: 5 Pages: 375-382
- DOI
  10.1093/jb/mvz067
- NAID
  40022069517
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15115, KAKENHI-PROJECT-19K16794
[Journal Article] Ablation of miR-146b in mice causes hematopoietic malignancy2018
- Author(s)
  Mitsumura Takahiro、Ito Yoshiaki、Chiba Tomoki、Matsushima Takahide、Kurimoto Ryota、Tanaka Yoko、Kato Tomomi、Uchida Keisuke、Ito Takashi、Yamamoto Kouhei、Eishi Yoshinobu、Kitagawa Masanobu、Miyazaki Yasunari、Inase Naohiko、Asahara Hiroshi
- Journal Title
  
  Blood Advances
  
  Volume: 2 Issue: 23 Pages: 3483-3491
- DOI
  10.1182/bloodadvances.2018017954
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19603, KAKENHI-PROJECT-18K15115, KAKENHI-PLANNED-26113008, KAKENHI-PROJECT-15H02560, KAKENHI-PROJECT-15K08421, KAKENHI-PROJECT-16K09576, KAKENHI-PROJECT-15K15026, KAKENHI-PROJECT-17K15018
[Patent] ハイスループット遺伝子編集技術2020
- Inventor(s)
  淺原弘嗣、栗本遼太、松島隆英、堤大樹
- Industrial Property Rights Holder
  淺原弘嗣、栗本遼太、松島隆英、堤大樹
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K16794
[Presentation] Regulation of lung cancer metastasis by the RNA-modifying enzyme2023
- Author(s)
  Ryota Kurimoto、Waka Miyamoto、Maiko Inotsume、Reiji Hirai、Tomoki Chiba、Takahide Matsushima、Yutaro Uchida、Yuta Fujii、Yuki Naito、Yuichi Shichino、Mari Mito、Shintaro Iwasaki、Hiroshi Asahara
- Organizer
  第24回日本RNA学会年会 2023.07.05
- Data Source
  KAKENHI-PROJECT-22K07226
[Presentation] RNA修飾酵素による肺がんの転移制御機構2023
- Author(s)
  栗本遼太 , 猪爪舞子 , 宮本和佳 , 錦織杏樹 , 千葉朋希 , 松島隆英 , 内田雄太郎 , 淺原弘嗣
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-22K07226
[Presentation] Regulation of lung cancer metastasis by the RNA-modifying enzyme2022
- Author(s)
  Ryota Kurimoto, Waka Miyamoto, Maiko Inotsume, Tomoki Chiba, TakahideMatsushima, YutaroUchida, Yuta Fujii, Hiroshi Asahara.
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-22K07226
[Presentation] RNA Modification Enzyme TruB1 Regulate Tumor Proliferation via MicroRNA let-7.2021
- Author(s)
  Kurimoto R, Asahara H
- Organizer
  International Association for the study of Lung Cancer 2020 World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16794
[Presentation] Tumor suppression potential of tRNA modification enzyme TruBs via let-72021
- Author(s)
  Ryota Kurimoto, Hiroki Tsutsumi, Saki lkeuchi, Hiroshi Asahara
- Organizer
  AACR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16794
[Presentation] The tumor suppression potential of RNA pseudouridine synthase family via microRNA regulation2020
- Author(s)
  Kurimoto R, Ikeuchi S, Asahara H
- Organizer
  The 18th meeting of Japan Society of Medical Oncology
- Data Source
  KAKENHI-PROJECT-19K16794
[Presentation] The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA.2020
- Author(s)
  Kurimoto R, Asahara H
- Organizer
  2nd RNAJ Online Meeting
- Data Source
  KAKENHI-PROJECT-19K16794
[Presentation] The tRNA pseudouridine synthase TruB1 regulates the maturation of let-7 miRNA.2020
- Author(s)
  Ryota KURIMOTO
- Organizer
  2nd RNAJ Online Meeting ~ mRNA/miRNA Metabolism ~
- Data Source
  KAKENHI-PROJECT-19KK0227
[Presentation] New regulatory mechanism of tumor suppressor microRNA let-7s2019
- Author(s)
  Ryota Kurimoto, Hiroki Tsutsumi, Maiko Inotsume, Hiroshi Asahara.
- Organizer
  16thn Bone Biology Forum
- Data Source
  KAKENHI-PROJECT-19K16794
[Presentation] miRNAs in arthritis pathogenesis and therapy2019
- Author(s)
  Sho Mokuda, Yoshiaki Ito, Masafumi Inui, Ryo Nakamichi, Tomoki Chiba, Ryota Kurimoto, Takahide Matsushima, and Hiroshi Asahara
- Organizer
  Keystone Symposia, Small Regulatory RNAs (D7)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15018
[Presentation] 腫瘍抑制microRNA let-7 familyの新たな制御機構の解明2019
- Author(s)
  猪爪舞子, 栗本遼太, 堤大樹, 細貝春香, 浅原弘嗣
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K16794
[Presentation] miRNAs in arthritis pathogenesis and therapy.2019
- Author(s)
  Hiroshi Asahara, Sho Mokuda, Yoshiaki Ito, Masafumi Inui, Ryo Nakamichi, Tomoki Chiba, Ryota Kurimoto, Takahide Matsushima.
- Organizer
  The 24th Annual Meeting of the RNA Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16794
[Presentation] 腫瘍抑制microRNA let-7 familyの新たな制御機構の解明2019
- Author(s)
  Ryota Kurimoto, Hiroki Tsutsumi, Yutaro Uchida, Hiroshi Asahara.
- Organizer
  第17回日本臨床腫瘍学会
- Data Source
  KAKENHI-PROJECT-19K16794
[Presentation] microRNA let-7 familyの新たな制御機構の解明2018
- Author(s)
  栗本遼太、堤大樹、伊藤義晃、浅原弘嗣
- Organizer
  第5回JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-17K15018

1. 淺原弘嗣 (70294460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 松島隆英 (40636560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 千葉朋希

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results

Kurimoto Ryota 栗本 遼太

KURIMOTO Ryota 栗本 遼太

Research Projects

Research Products

Co-Researchers

新規mRNA修飾酵素によるがん浸潤転移制御の解明と治療応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

白血病における腫瘍抑制マイクロRNA let-7の新規制御機構の解明と治療応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

International research collaboration on inflammatory diseases and regenerative medicine by linking human tissue banks and drug discovery

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of novel regulators of tumor suppressor microRNA let-7 and search for novel therapeutic targetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of eIF2gamma in Lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The essential role of Mkx in periodontal ligament on the metabolism of alveolar bone and cementum2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] One‐step generation of mice with gene editing by <i>Tol2</i> transposon‐dependent <scp>gRNA</scp> delivery2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of chemical compounds regulating PD‐L1 by introducing HiBiT‐tagged cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vitro Neo-Genesis of Tendon/Ligament-Like Tissue by Combination of Mohawk and a Three-Dimensional Cyclic Mechanical Stretch Culture System2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Transcriptional, epigenetic and microRNA regulation of growth plate2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The tRNA pseudouridine synthase TruB1 regulates the maturation of let‐7 miRNA2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcriptome analysis of sevoflurane exposure effects at the different brain regions.2020

Author(s)

Journal Title

DOI

Kurimoto Ryota 栗本遼太

KURIMOTO Ryota 栗本遼太