Kim HyunJin Kim HyunJin

Researcher Number	10755002
Other IDs	https://orcid.org/0000-0003-4232-3441
Affiliation (based on the past Project Information) *help	2018 – 2019: 東京大学, 大学院医学系研究科(医学部), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 90120:Biomaterials-related
Keywords	Principal Investigator CRISPR-Cas technology / amphiphile / mRNA transfection / cationic polymer / CRISPR-Casテクノロジー / mRNA 配送 / カチオン性ポリマー

Fine-tuning of polymer amphiphile for high performance of messenger RNA deliveryPrincipal Investigator
- Principal Investigator
  
  Kim HyunJin
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Tokyo

All 2019 2018

All Journal Article Presentation Patent

[Journal Article] Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells.2019
- Author(s)
  Y. Yi, H. J. Kim, M. Zheng, P. Mi, M. Naito, B. S. Kim, H. S. Min, K. Hayashi, F. Perche, K. Toh, X. Liu, Y. Mochida, H. Kinoh, H. Cabral, K. Miyata, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 295 Pages: 268-277
- DOI
  10.1016/j.jconrel.2019.01.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K18378, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18K18391, KAKENHI-PROJECT-18K18379
[Journal Article] Fine-Tuning of Hydrophobicity in Amphiphilic Polyaspartamide Derivatives for Rapid and Transient Expression of Messenger RNA Directed Toward Genome Engineering in Brain2019
- Author(s)
  Kim Hyun Jin、Ogura Satomi、Otabe Takahiro、Kamegawa Rimpei、Sato Moritoshi、Kataoka Kazunori、Miyata Kanjiro
- Journal Title
  
  ACS Central Science
  
  Volume: 5 Issue: 11 Pages: 1866-1875
- DOI
  10.1021/acscentsci.9b00843
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18378
[Patent] AMPHIPHILIC POLY(AMINO ACID), BLOCK COPOLYMER USING THE AMPHIPHILIC POLY(AMINO ACID), AND COMPLEX INCLUDING THE AMPHIPHILIC POLY(AMINO ACID) OR THE BLOCK COPOLYMER AND NUCLEIC ACID2019
- Inventor(s)
  H.J. Kim, K. Miyata, K. Kataoka
- Industrial Property Rights Holder
  H.J. Kim, K. Miyata, K. Kataoka
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18K18378
[Patent] 両親媒性ポリアミノ酸、該両親媒性ポリアミノ酸を用いたブロックコポリマー、および該両親媒性ポリアミノ酸または該ブロックコポリマーと核酸とを含む複合体2018
- Inventor(s)
  キムヒョンジュン, 宮田完二郎、片岡一則
- Industrial Property Rights Holder
  キムヒョンジュン, 宮田完二郎、片岡一則
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K18378
[Presentation] Tuning of Hydrophobicity in Amphiphilic Polymers for mRNA Delivery and Their Application for CRISPR-Cas9 Technology2019
- Author(s)
  Hyun Jin Kim, Kazunori Kataoka, Kanjiro Miyata
- Organizer
  12th Annual Symposium on Nanobiotechnology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18378
[Presentation] Adjustment of Hydrophobicity in Amphiphilic Polymers For Highly Efficient Messenger RNA Delivery2019
- Author(s)
  Hyun Jin Kim, Moritoshi Sato, Kazunori Kataoka, Kanjiro Miyata
- Organizer
  6th International Conference on Multifunctional, Hybrid and Nanomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18378
[Presentation] Cationic Amphiphilic Polymer Development for Cas9 mRNA and its Application2019
- Author(s)
  Hyun Jin Kim, Satomi Ogura, Kazunori Kataoka, Kanjiro Miyata
- Organizer
  Nano Korea 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18378
[Presentation] Disease Responsive Nanomedicine-Polymeric Assembly for Oligonucleotide Delivery2019
- Author(s)
  Hyun Jin Kim, Kazunori Kataoka, Kanjiro Miyata
- Organizer
  Korean Chemical Society 2019
- Invited
- Data Source
  KAKENHI-PROJECT-18K18378
[Presentation] Cationic Polymer Synthesis Based on Optimization of Hydrophobicity for mRNA2019
- Author(s)
  Hyun Jin Kim, Kazunori Kataoka, Kanjiro Miyata
- Organizer
  68th SPSJ Annual Meeting
- Data Source
  KAKENHI-PROJECT-18K18378
[Presentation] Development of amphiphilic polymers for CRISPR-Cas9 mRNA delivery2018
- Author(s)
  Hyun Jin Kim, Kazunori Kataoka, Kanjiro Miyata
- Organizer
  5th COINS Symposium
- Data Source
  KAKENHI-PROJECT-18K18378
[Presentation] Development of Thiol-Crosslinked Micelle for Systemic Delivery of Antisense Oligonucleotide to Treat Brain Disease2018
- Author(s)
  Hyun Jin Kim, Hyun Su Min, Keisaku Katsushima, Yutaka Kondo, Kanjiro Miyata, Kazunori Kataoka
- Organizer
  第67回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K18378

1. 喜納宏昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 劉学瑩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kim HyunJin Kim HyunJin

Research Projects

Research Products

Co-Researchers

Fine-tuning of polymer amphiphile for high performance of messenger RNA deliveryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fine-Tuning of Hydrophobicity in Amphiphilic Polyaspartamide Derivatives for Rapid and Transient Expression of Messenger RNA Directed Toward Genome Engineering in Brain2019

Author(s)

Journal Title

DOI

Data Source

[Patent] AMPHIPHILIC POLY(AMINO ACID), BLOCK COPOLYMER USING THE AMPHIPHILIC POLY(AMINO ACID), AND COMPLEX INCLUDING THE AMPHIPHILIC POLY(AMINO ACID) OR THE BLOCK COPOLYMER AND NUCLEIC ACID2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] 両親媒性ポリアミノ酸、該両親媒性ポリアミノ酸を用いたブロックコポリマー、および該両親媒性ポリアミノ酸または該ブロックコポリマーと核酸とを含む複合体2018

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Tuning of Hydrophobicity in Amphiphilic Polymers for mRNA Delivery and Their Application for CRISPR-Cas9 Technology2019

Author(s)

Organizer

Data Source

[Presentation] Adjustment of Hydrophobicity in Amphiphilic Polymers For Highly Efficient Messenger RNA Delivery2019

Author(s)

Organizer

Data Source

[Presentation] Cationic Amphiphilic Polymer Development for Cas9 mRNA and its Application2019

Author(s)

Organizer

Data Source

[Presentation] Disease Responsive Nanomedicine-Polymeric Assembly for Oligonucleotide Delivery2019

Author(s)

Organizer

Data Source

[Presentation] Cationic Polymer Synthesis Based on Optimization of Hydrophobicity for mRNA2019

Author(s)

Organizer

Data Source

[Presentation] Development of amphiphilic polymers for CRISPR-Cas9 mRNA delivery2018

Author(s)

Organizer

Data Source

[Presentation] Development of Thiol-Crosslinked Micelle for Systemic Delivery of Antisense Oligonucleotide to Treat Brain Disease2018

Author(s)

Organizer

Data Source