Chinen Yoshiaki 知念良顕

Researcher Number	10757602
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Affiliation (based on the past Project Information) *help	2017 – 2018: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2016: 京都府立医科大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator General medical chemistry Except Principal Investigator Hematology
Keywords	Principal Investigator 難治性B細胞腫瘍 / CDKN2A / 染色体微小領域欠損 / B細胞性リンパ腫 / CDKN2A/B欠失 / FISH法 Except Principal Investigator 成人T細胞白血病・リンパ腫 / びまん性大細胞型Bリンパ腫 / MYC遺伝子 / PVT1遺伝子 … More / 非コード遺伝子 / 遺伝子増幅 / long noncoding RNA / PVT1 / キメラmRNA / 8q24染色体異常 / 難治性リンパ腫 Less

Molecular cytogenetic studies of MYC and PVT1 rearrangements in refractory and relapsed lymphoma
- Principal Investigator
  
  Taniwaki Masafumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
Development of novel diagnostic and therapeutic approach for the diffuse large B cell lymphoma with CDKN2A deletionPrincipal Investigator
- Principal Investigator
  
  Chinen Yoshiaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto Prefectural University of Medicine

All 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] A novel method of amplified fluorescent in situ hybridization for detection of chromosomal microdeletions in B cell lymphoma2019
- Author(s)
  Mizuno Y, Chinen Y, Tsukamoto T, Takimoto-Shimomura T, Matsumura-Kimoto Y, Fujibayashi Y, Kuwahara-Ota S, Fujino T, Nishiyama D, Shimura Y, Kobayashi T, Horiike S, Taniwaki M, Kuroda J
- Journal Title
  
  International Journal of Hematology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K21284
[Journal Article] A novel method of amplified fluorescent in situ hybridization for detection of chromosomal microdeletions in B cell lymphoma.2019
- Author(s)
  Mizuno Y, Chinen Y, Tsukamoto T, Takimoto-Shimomura T, Matsumura-Kimoto Y, Fujibayashi Y, Kuwahara-Ota S, Fujino T, Nishiyama D, Shimura Y, Kobayashi T, Horiike S, Taniwaki M, Kuroda J.
- Journal Title
  
  Int J Hematol.
  
  Volume: 109 Issue: 5 Pages: 593-602
- DOI
  10.1007/s12185-019-02617-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09856, KAKENHI-PROJECT-16K21284
[Journal Article] Dual targeting of bromodomain-containing 4 by AZD5153 and BCL2 by AZD4320 against B-cell lymphomas concomitantly overexpressing c-MYC and BCL22018
- Author(s)
  Takimoto-Shimomura Tomoko、Tsukamoto Taku、Maegawa Saori、Fujibayashi Yuto、Matsumura-Kimoto Yayoi、Mizuno Yoshimi、Chinen Yoshiaki、Shimura Yuji、Mizutani Shinsuke、Horiike Shigeo、Taniwaki Masafumi、Kobayashi Tsutomu、Kuroda Junya
- Journal Title
  
  Investigational New Drugs
  
  Volume: 37 Issue: 2 Pages: 210-222
- DOI
  10.1007/s10637-018-0623-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09856
[Journal Article] Prognostic impact of a past or synchronous second cancer in diffuse large B cell lymphoma.2018
- Author(s)
  Tanba K, Chinen Y, Uchiyama H, Uoshima N, Shimura K, Fuchida S, Kiyota M, Nakao M, Shimura Y, Kobayashi T, Horiike S, Wada K, Shimazaki C, Kaneko H, Kobayashi Y, Taniwaki M, Kuroda J.
- Journal Title
  
  Blood Cancer J.
  
  Volume: 8 Issue: 1 Pages: 1-5
- DOI
  10.1038/s41408-017-0043-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09856, KAKENHI-PROJECT-16K21284
[Journal Article] Establishment and Characteristics of a Novel Mantle Cell Lymphoma-derived Cell Line and a Bendamustine-resistant Subline2018
- Author(s)
  Takimoto-Shimomura T, Nagoshi H, Maegawa S, Fujibayashi Y, Tsukamoto T, Matsumura-Kimoto Y, Mizuno Y, Chinen Y, Mizutani S, Shimura Y, Horiike S, Taniwaki M, Kobayashi T, Kuroda J
- Journal Title
  
  Cancer Genomics Proteomics
  
  Volume: 15 Pages: 213-223
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09856
[Journal Article] Chromosomal abnormality variation detected by G-banding is associated with prognosis of diffuse large B-cell lymphoma treated by R-CHOP-based therapy.2018
- Author(s)
  Mizuno Y, Tsukamoto T, Kawata E, Uoshima N, Uchiyama H, Yokota I, Maegawa S, Takimoto T, Tanba K, Matsumura-Kimoto Y, Kuwahara-Ota S, Fujibayashi Y, Yamamoto-Sugitani M, Chinen Y, Shimura Y, Horiike S, Taniwaki M, Kobayashi T, Kuroda J.
- Journal Title
  
  Cancer Med.
  
  Volume: 7 Issue: 3 Pages: 655-664
- DOI
  10.1002/cam4.1342
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09856
[Journal Article] Prognostic impact of a past or synchronous second cancer in diffuse large B cell lymphoma2018
- Author(s)
  Kazuna Tanba, Yoshiaki Chinen, Hitoji Uchiyama, Nobuhiko Uoshima, Kazuho Shimura, Shinichi Fuchida, Miki Kiyota, Mitsushige Nakao, Yuji Shimura, Tsutomu Kobayashi, Shigeo Horiike, Katsuya Wada, Chihiro Shimazaki, Hiroto Kaneko, Yutaka Kobayashi, Masafumi Taniwaki, Junya Kuroda
- Journal Title
  
  Blood Cancer Journal
  
  Volume: 1 Pages: 1-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K21284
[Journal Article] Detection of chromosomal abnormalities by G-banding and prognostic impact in follicular lymphoma in the rituximab era.2017
- Author(s)
  Tsukamoto T, Kiyota M, Kawata E, Uoshima N, Tatekawa S, Chinen Y, Nagoshi H, Mizutani S, Shimura Y, Yamamoto-Sugitani M, Kobayashi T, Horiike S, Yasukawa S, Yanagisawa A, Taniwaki M, Kuroda J.
- Journal Title
  
  Int J Hematol.
  
  Volume: 105 Issue: 5 Pages: 658-667
- DOI
  10.1007/s12185-016-2166-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09856
[Journal Article] Epigenetic repression of miR-375 is the dominant mechanism for constitutive activation of the PDPK1/RPS6KA3 signalling axis in multiple myeloma.2017
- Author(s)
  Tatekawa S, Chinen Y, Ri M, Narita T, Shimura Y, Matsumura-Kimoto Y, Tsukamoto T, Kobayashi T, Kawata E, Uoshima N, Taki T, Taniwaki M, Handa H, Iida S, Kuroda J.
- Journal Title
  
  British Journal of Haematology
  
  Volume: 印刷中 Issue: 4 Pages: 534-546
- DOI
  10.1111/bjh.14707
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461429, KAKENHI-PROJECT-16K21284
[Journal Article] Molecular heterogeneity in APIP-FGFR2 fusion transcripts with diversity of genomic breakpoints in gastric cancer high-level amplifications at 11p13 and 10q262017
- Author(s)
  Okuda T, Taki T, Nishida K Chinen Y, Nagoashi H, Sakakura C, Ohtsuji E, Taniwaki M
- Journal Title
  
  Oncol Lett
  
  Volume: 13 Issue: 1 Pages: 215-221
- DOI
  10.3892/ol.2016.5386
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09486, KAKENHI-PROJECT-16K09856, KAKENHI-PROJECT-16K10512
[Presentation] 増幅FISH法によるB細胞リンパ腫のCDKN2A微小欠損の検出2018
- Author(s)
  水野芳美, 知念良顕, 塚本拓, 下村とも子, 志村勇司, 古林勉, 堀池重夫, 谷脇雅史, 黒田純也
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09856
[Presentation] B細胞リンパ腫細胞株から検出した新規キメラ遺伝子PVT1-ELK2AP2018
- Author(s)
  松本洋典, 滝智彦, 知念良顕, 佐々木奈々, 吉田美穂子, 堤康彦, 名越久朗, 志村和穂, 兼子裕人, 堀池重夫, 黒田純也, 谷脇雅史
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09856
[Presentation] 増幅FISH法によるB細胞リンパ腫のCDKN2A微小欠損の検出2018
- Author(s)
  水野芳美, 知念良顕, 塚本拓, 下村とも子, 志村勇司, 古林勉, 堀池重夫, 谷脇雅史, 黒田純也
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K21284
[Presentation] Cyclin D1 transcript variant in mantle cell lymphoma and myeloma with chromosome 11q13 abnormality2017
- Author(s)
  Yoshiaki Chinen, Taku Tsukamoto, Yayoi Kimoto, Tomoko Takimoto, Yoshimi Mizuno, Saori Maegata, Saeko Ota, Kazuna Tanba, Yuji Shimura, Tsutomu Kobayashi, Shigeo Horiike, Junya Kuroda
- Organizer
  第79回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-16K21284
[Presentation] Chromosomal abnormalities and prognostic impacts in follicular lymphoma in the era of Rituximab.2017
- Author(s)
  Tsukamoto T, Kawata E, Uoshima N, Chinen Y, Shimura Y, Yamamoto-Sugitani M, Kobayashi T, Horiike S, Yasukawa S, Yanagisawa A, Taniwaki M, Kuroda J.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09856
[Presentation] Prognostic Impact of Past History of Other Malignancies in Diffuse Large B Cell Lymphoma2017
- Author(s)
  Kazuna Tanba, Yoshiaki Chinen, Hitoji Uchiyama, Nobuhiko Uoshima, Kazuho Shimura, Shin-ichi Fuchida, Miki Kiyota, Mitsushige Nakao, Yuji Shimura, Tsutomu Kobayashi, Shigeo Horiike, Katsuya Wada, Chihiro Shimazaki, Hiroto Kaneko, Yutaka Kobayashi, Masafumi Taniwaki, Junya Kuroda
- Organizer
  American society of Hematology, 59th Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21284
[Presentation] The epigenetic dysregulation of miR-375 for PDPK1 overexpression/activation in multiple myeloma2016
- Author(s)
  Shotaro Tatekawa, Yoshiaki Chinen, Yuji Shimura, Yayoi Matsumura-Kimoto, Hisao Nagoshi, Tsutomu Kobayashi, Eri Kawata, Tomoko Narita, Masaki Ri, Hiroshi Handa, Nobuhiko Uoshima, Shinsuke Iida, Junya Kuroda
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K21284
[Presentation] The epigenetic dysregulation of miR-375 for PDPK1 overexpression/activation in multiple myeloma2016
- Author(s)
  Shotaro Tatekawa, Yoshiaki Chinen, Yuji Shimura, Hisao Nagoshi, Tutor Kobayashi, Yayoi Kimoto, Eri Kawata, Tomoko Narita, Masaki Ri, Hiroshi Handa, Nobuhiko Uoshima, Shinsuke Iida, Junya Kuroda
- Organizer
  第41回日本骨髄腫学会学術集会
- Place of Presentation
  あわぎんホール（徳島県徳島市）
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-16K21284
[Presentation] Novel tumor-specific CCND1 isoforms in mantle cell lymphoma and myeloma with 11q23 abnormality2016
- Author(s)
  Yoshiaki Chinen, Shotaro Tatekawa, Saori Maegawa, Tomoko Takimoto, Hisao Nagoshi, Yuji Shimura, Mio Yamamoto-Sugitani, Tustomu Kobayashi, Shigeo Horiike, Masafumi Taniwaki, Junya Kuroda
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K21284
[Presentation] The role of aberrant PDPK1-RSK2 signaling pathway activation in multiple myeloma2016
- Author(s)
  Yoshiaki Chinen
- Organizer
  第41回日本骨髄腫学会学術集会
- Place of Presentation
  あわぎんホール（徳島県徳島市）
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-16K21284
[Presentation] Karyotypic evolution in the prognostic indexes-defined high-risk diffuse large B cell lymphoma.2016
- Author(s)
  Mizuno Y, Kobayashi T, Shimura Y, Tatekawa S, Tsukamoto T, Maegawa S, Tanba K, Kimoto-Matsumura Y, Takimoto T, Kuwahara S, Chinen Y, Nagoshi H, Sugitani-Yamamoto M, Horiike S, Taniwaki M, Kuroda J.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09856
[Presentation] More Somatic Mutations Including Those in the Aid-Motif with High-Risk, Histologically Non-Transformed Follicular Lymphomas.2016
- Author(s)
  Tsukamoto T, Nakano M, Sato R, Adachi H, Kiyota M, Yasukawa S, Tatekawa S, Chinen Y, Nagoshi H, Mizutani S, Shimura Y, Yamamoto-Sugitani M, Kobayashi T, Taki T, Horiike S, Yanagisawa A, Taniwaki M, Tashiro K, Kuroda J.
- Organizer
  58th The American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  San Diego. USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09856
[Presentation] PDPK1 is the potential therapeutic target in mantle cell lymphoma.2016
- Author(s)
  Maegawa S, Tatekawa S, Chinen Y, Tsukamoto T, Tanba K, Kimoto-Matsumura Y, Takimoto T, Mizuno Y, Sugitani-Yamamoto M, Taniwaki M, Kuroda J.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09856
[Presentation] The Abnormal Repression of Mir-375 Expression By Overlapping Epigenetic Dysregulations in Myelomas2016
- Author(s)
  Shotaro Tatekawa, Yoshiaki Chinen, Yuji Shimura, Yayoi Matsumura-Kimoto, Hisao Nagoshi, Tsutomu Kobayashi, Eri Kawata, Tomoko Narita, Masaki Ri, Hiroshi Handa, Nobuhiko Uoshima, Shinsuke Iida, Junya Kuroda
- Organizer
  American society of Hematology, 58th Annual Meeting and Exposition
- Place of Presentation
  San Diego (USA)
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21284
[Presentation] Comprehensive analysis of conjoined genes in DLBCL cell line, KPUM-UH1 by RNA-Seq.2016
- Author(s)
  Matsumoto Y, Taki T, Chinen Y, Sato R, Adachi H, Mizutani S, Nagoshi H, Shimura Y, Yoshida M, Sugitani-Yamamoto M, Kobayashi T, Kuroda J, Shimura K, Nakano M, Horiike S, Ohkawara Y, Tashiro K, Taniwaki M.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09856

1. Taniwaki Masafumi (80163640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 名越久朗 (80713924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. KURODA Junya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 滝智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Chinen Yoshiaki 知念 良顕

Research Projects

Research Products

Co-Researchers

Molecular cytogenetic studies of MYC and PVT1 rearrangements in refractory and relapsed lymphoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel diagnostic and therapeutic approach for the diffuse large B cell lymphoma with CDKN2A deletionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A novel method of amplified fluorescent in situ hybridization for detection of chromosomal microdeletions in B cell lymphoma2019

Author(s)

Journal Title

Data Source

[Journal Article] A novel method of amplified fluorescent in situ hybridization for detection of chromosomal microdeletions in B cell lymphoma.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dual targeting of bromodomain-containing 4 by AZD5153 and BCL2 by AZD4320 against B-cell lymphomas concomitantly overexpressing c-MYC and BCL22018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic impact of a past or synchronous second cancer in diffuse large B cell lymphoma.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment and Characteristics of a Novel Mantle Cell Lymphoma-derived Cell Line and a Bendamustine-resistant Subline2018

Author(s)

Journal Title

Data Source

[Journal Article] Chromosomal abnormality variation detected by G-banding is associated with prognosis of diffuse large B-cell lymphoma treated by R-CHOP-based therapy.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic impact of a past or synchronous second cancer in diffuse large B cell lymphoma2018

Author(s)

Journal Title

Data Source

[Journal Article] Detection of chromosomal abnormalities by G-banding and prognostic impact in follicular lymphoma in the rituximab era.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epigenetic repression of miR-375 is the dominant mechanism for constitutive activation of the PDPK1/RPS6KA3 signalling axis in multiple myeloma.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular heterogeneity in APIP-FGFR2 fusion transcripts with diversity of genomic breakpoints in gastric cancer high-level amplifications at 11p13 and 10q262017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 増幅FISH法によるB細胞リンパ腫のCDKN2A微小欠損の検出2018

Author(s)

Organizer

Data Source

[Presentation] B細胞リンパ腫細胞株から検出した新規キメラ遺伝子PVT1-ELK2AP2018

Author(s)

Organizer

Data Source

[Presentation] 増幅FISH法によるB細胞リンパ腫のCDKN2A微小欠損の検出2018

Author(s)

Organizer

Data Source

[Presentation] Cyclin D1 transcript variant in mantle cell lymphoma and myeloma with chromosome 11q13 abnormality2017

Author(s)

Organizer

Data Source

[Presentation] Chromosomal abnormalities and prognostic impacts in follicular lymphoma in the era of Rituximab.2017

Chinen Yoshiaki 知念良顕