Watanabe Masahiro 渡邊政博

Researcher Number	10758246
Other IDs
Affiliation (Current)	2025: 就実大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 就実大学, 薬学部, 准教授 2018 – 2022: 就実大学, 薬学部, 講師 2015 – 2018: 就実大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Applied pharmacology Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Applied pharmacology
Keywords	Principal Investigator DAMPs / 相互作用 / AGEs / 終末糖化産物 / HMGB1 / ダメージ関連分子パターン / サイトカイン / 慢性炎症 / 炎症 / リボソームタンパク質 / LPS / 炎症性サイトカイン … More Except Principal Investigator … More 炎症 / サイトカイン / 組織リモデリング / 自然免疫 / 医療薬学 / 分子標的 Less

炎症性疾患の新規治療標的としてのDAMPsインタラクトームの解明Principal Investigator
- Principal Investigator
  
  渡邊政博
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
内因性ＡＧＥをコアとする組織リモデリング病態の増悪化機序解明と根治的治療法の開発
- Principal Investigator
  
  森秀治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
Elucidation of the mechanism of tissue remodeling exacerbated by endogenous AGEs and the development of novel targeted therapy
- Principal Investigator
  
  MORI Shuji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
Identification of inflammation suppressive DAMPs and their pathophysiological significance in inflammatory diseasesPrincipal Investigator
- Principal Investigator
  
  WATANABE Masahiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
Study of the pathophysiological significance of endogenous AGE as an exacerbating factor for tissue remodeling, and the development of novel targeted therapy
- Principal Investigator
  
  MORI Shuji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
Elucidation of the pathogenic mechanism of chronic inflammation based on AGE-induced cytokine trappingPrincipal Investigator
- Principal Investigator
  
  Watanabe Masahiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
Roles of AGEs as exacerbation factor in pathogenesis of tissue remodeling and the development of novel targeted therapy
- Principal Investigator
  
  MORI Shuji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Shujitsu University
Elucidating the molecular bases and pathophysiological significances of the extracellular inflammasome which drives chronic inflammationPrincipal Investigator
- Principal Investigator
  
  Watanabe Masahiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Applied pharmacology
- Research Institution
  Shujitsu University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Glycolaldehyde-derived advanced glycation end products promote macrophage proliferation via the JAK-STAT signaling pathway2023
- Author(s)
  Toyomura Takao、Watanabe Masahiro、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 50 Issue: 7 Pages: 5849-5858
- DOI
  10.1007/s11033-023-08509-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10465, KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06657, KAKENHI-PROJECT-21K06701
[Journal Article] Cationic ribosomal proteins can inhibit pro‐inflammatory action stimulated by LPS+HMGB1 and are hindered by advanced glycation end products2023
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Biotechnology and Applied Biochemistry
  
  Volume: 71 Issue: 2 Pages: 264-271
- DOI
  10.1002/bab.2538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06657, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
[Journal Article] Nordihydroguaiaretic acid inhibits glyoxalase I, and causes the accumulation of methylglyoxal followed by cell-growth inhibition2022
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Ikegami Ryo、Suwaki Yui、Sada Minami、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 49 Issue: 11 Pages: 10499-10507
- DOI
  10.1007/s11033-022-07929-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
[Journal Article] Identification of ribosomal protein L9 as a novel regulator of proinflammatory damage-associated molecular pattern molecules2022
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 49 Issue: 4 Pages: 2831-2838
- DOI
  10.1007/s11033-021-07096-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
[Journal Article] 終末糖化産物AGEsは，IL-17A共存下において破骨細胞の分化を亢進する．2021
- Author(s)
  豊村隆男，渡邊政博，森秀治
- Journal Title
  
  就実大学薬学雑誌
  
  Volume: 8 Pages: 46-54
- NAID
  120007035345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14969
[Journal Article] グルタチオンS-トランスフェラーゼとグルタチオンとの相互作用をモデルとした示差走査蛍光定量法による分子間相互作用の解析に関する検討2021
- Author(s)
  渡邊政博，豊村隆男，森秀治
- Journal Title
  
  就実大学薬学雑誌
  
  Volume: 8 Pages: 85-91
- NAID
  120007035334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14969
[Journal Article] AGEs-RAGE系によるがん発症リスクと新規治療戦略2020
- Author(s)
  豊村隆男，渡邊政博，森秀治
- Journal Title
  
  就実大学薬学雑誌
  
  Volume: 7 Pages: 19-27
- NAID
  120006850649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14969
[Journal Article] Advanced glycation end products (AGEs) synergistically potentiated the proinflammatory action of lipopolysaccharide (LPS) and high mobility group box-1 (HMGB1) through their direct interactions.2020
- Author(s)
  Watanabe M, Toyomura T, Tomiyama M, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S.
- Journal Title
  
  Mol Biol Rep.
  
  Volume: 47(9) Issue: 9 Pages: 7153-7159
- DOI
  10.1007/s11033-020-05783-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-18K06807, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K14969
[Journal Article] 抗菌薬適正使用支援活動によるデ・エスカレーションの向上が血培養陽性患者アウトカムに及ぼす影響2020
- Author(s)
  田井達也，山口佳津騎，渡邊政博，井上達也，元木貴大，田中裕章，間嶋由美子，根ヶ山清，横田恭子，加地雅人，小坂信二，芳地一
- Journal Title
  
  医療薬学
  
  Volume: 46 Pages: 314-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14969
[Journal Article] Towards Understanding the Pathophysiological Significance of Cytokine Trapping Mediated by Advanced Glycation End Products2020
- Author(s)
  Watanabe Masahiro
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 140 Issue: 11 Pages: 1335-1341
- DOI
  10.1248/yakushi.20-00154
- NAID
  130007933473
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2020-11-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14969
[Journal Article] Differential contribution of possible pattern‐recognition receptors to advanced glycation end product?induced cellular responses in macrophage‐like RAW264.7 cells2019
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Liu Keyue、Teshigawara Kiyoshi、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Biotechnology and Applied Biochemistry
  
  Volume: in press Issue: 2 Pages: 265-272
- DOI
  10.1002/bab.1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-18K14969, KAKENHI-PROJECT-18K06807
[Journal Article] The C‐terminal region of tumor necrosis factor like weak inducer of apoptosis is required for interaction with advanced glycation end products2018
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Liu Keyue、Teshigawara Kiyoshi、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Biotechnology and Applied Biochemistry
  
  Volume: 66 Issue: 2 Pages: 254-260
- DOI
  10.1002/bab.1706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14969, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-18K06807
[Journal Article] Advanced glycation end products attenuate the function of tumor necrosis factor-like weak inducer of apoptosis to regulate the inflammatory response2017
- Author(s)
  Watanabe M, Toyomura T, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S
- Journal Title
  
  Molecular and Cellular Biochemistry
  
  Volume: 印刷中 Issue: 1-2 Pages: 153-162
- DOI
  10.1007/s11010-017-3045-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06785, KAKENHI-PROJECT-15K08605, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15K08253
[Presentation] 抑制性DAMPsとしてのリボソーム構成分子RPL9の同定2022
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，西中崇，ハティポールオメルファルク，高橋英夫，西堀正洋，森　秀治
- Organizer
  第141回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06701
[Presentation] 新規AGEs結合分子AGE-BP2がDAMPsの作用に与える影響の解析2021
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，西中崇，逢坂大樹，王登莉，高橋英夫，西堀正洋，森秀治
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06701
[Presentation] AGEsの共存がDAMPsの作用に与える影響の検討2020
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] 新規AGEs結合分子AGE-BP2の作用の検討2020
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治，
- Organizer
  第138回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] AGEsとの複合体形成によるDAMPsの作用変化2020
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第59回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] AGEs結合因子の単離とAGEs-RAGE結合抑制領域の同定2020
- Author(s)
  森秀治，渡邊政博，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，豊村隆男
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] TLR2によるAGE2依存的な細胞増殖制御2020
- Author(s)
  豊村隆男，渡邊政博，和氣秀徳，逢坂大樹，王登莉，高橋英夫，西堀正洋，森秀治
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] 終末糖化産物AGE2による細胞増殖効果とTLR2による制御2020
- Author(s)
  豊村隆男，渡邊政博，和氣秀徳，逢坂大樹，王登莉，高橋英夫，西堀正洋，森秀治
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] AGEs結合因子の単離と受容体遮断領域の探索研究2020
- Author(s)
  森秀治，渡邊政博，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，豊村隆男
- Organizer
  第41回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] AGEs結合因子としてのLfの同定とマクロファージTNF-α発現応答変化2019
- Author(s)
  森秀治，渡邊政博，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，豊村隆男
- Organizer
  第40回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] 炎症誘発活性を有する新規AGEs結合分子の同定2019
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第135回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] AGEs結合因子の分子同定と炎症性サイトカイン発現応答への影響2019
- Author(s)
  森秀治，渡邊政博，和氣秀徳，勅使川原匡，劉克約，高橋英夫，西堀正洋，豊村隆男
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] AGEsとDAMPsの協調作用の検討2019
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] Advanced glycation end products interact with lactoferrin, and change the lactoferrin- stimulated proinflammatory cytokine response2019
- Author(s)
  Mori S, Watanabe M, Wake H, Teshigawara K, Liu K, Takahashi H, Nishibori M, Toyomura T
- Organizer
  9th International DAMPs and Alarmins symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] AGEs－Lf相互作用に基づく炎症性サイトカイン応答の変化2019
- Author(s)
  森秀治，渡邊政博，和氣秀徳，勅使川原匡，劉克約，高橋英夫，西堀正洋，豊村隆男
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] 新規AGEs結合分子の性状の解析2019
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第31回創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] 終末糖化産物によるサイトカイン捕捉機構の同定と病態生理学的意義の解明2019
- Author(s)
  渡邊政博
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] AGEs と炎症関連分子の共存が炎症反応に与える変化の検討2019
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第136回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] AGEsとDAMPsの協調作用の検討2019
- Author(s)
  渡邊政博　他
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-18K06807
[Presentation] AGEs共存による起炎分子としてのラクトフェリンの作用の変化2018
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第30回創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] AGEsがラクトフェリンの作用に与える影響の解析2018
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] 遺伝子改変細胞を用いたDAMPs分子の作用メカニズム解析2018
- Author(s)
  渡邊政博他
- Organizer
  第133回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K06807
[Presentation] 遺伝子改変細胞を用いたDAMPs分子の作用メカニズム解析2018
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第133回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] DAMPs受容体欠損細胞の作製とその性状の評価2018
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第29回創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] 受容体欠損細胞を用いたDAMPs分子の機能解析2018
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-18K14969
[Presentation] ゲノム編集によるAGEsの作用メカニズム解析プラットフォームの構築2017
- Author(s)
  渡邊政博　他
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15K08605
[Presentation] AGEsによるTNF関連分子の機能変化2016
- Author(s)
  渡邊政博　他
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都大学百周年時計台記念館（京都市）
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-15K08605
[Presentation] AGEs 共存による Damps 関連サイトカイン類の機能変化2016
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H06785
[Presentation] AGEsとTNF関連サイトカインとの相互作用部位の解析2016
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第26回創薬・薬理フォーラム
- Place of Presentation
  岡山大学医学部（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-15H06785
[Presentation] Damps関連サイトカインの機能に対するAGEsの影響2016
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター／東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15H06785
[Presentation] HMGB1と相互作用するサイトカインに対するAGEsの影響2015
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  BMB2015 第38回日本分子生物学会，第88回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド（神戸ポートピアホテル，神戸国際会議場，神戸国際展示場，神戸商工会議所）（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H06785
[Presentation] HMGB1と相互作用するサイトカインに対するAGEsの影響2015
- Author(s)
  渡邊政博
- Organizer
  第38回日本分子生物学会・第88回日本生化学会合同大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08605

1. MORI Shuji (50220009)

# of Collaborated Projects: 7 results

# of Collaborated Products: 7 results
2. TOYOMURA Takao (40425137)

# of Collaborated Projects: 7 results

# of Collaborated Products: 7 results
3. WAKE Hidenori

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
4. RYU Katsuyaku

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 高橋英夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
6. 西中崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. ハティポールオメル・ファルク

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
8. 勅使川原匡

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 西堀正洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Watanabe Masahiro 渡邊 政博

Research Projects

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Co-Researchers

炎症性疾患の新規治療標的としてのDAMPsインタラクトームの解明Principal Investigator

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内因性ＡＧＥをコアとする組織リモデリング病態の増悪化機序解明と根治的治療法の開発

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Elucidation of the mechanism of tissue remodeling exacerbated by endogenous AGEs and the development of novel targeted therapy

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Identification of inflammation suppressive DAMPs and their pathophysiological significance in inflammatory diseasesPrincipal Investigator

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Study of the pathophysiological significance of endogenous AGE as an exacerbating factor for tissue remodeling, and the development of novel targeted therapy

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Elucidation of the pathogenic mechanism of chronic inflammation based on AGE-induced cytokine trappingPrincipal Investigator

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Roles of AGEs as exacerbation factor in pathogenesis of tissue remodeling and the development of novel targeted therapy

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Elucidating the molecular bases and pathophysiological significances of the extracellular inflammasome which drives chronic inflammationPrincipal Investigator

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[Journal Article] Glycolaldehyde-derived advanced glycation end products promote macrophage proliferation via the JAK-STAT signaling pathway2023

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DOI

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[Journal Article] Cationic ribosomal proteins can inhibit pro‐inflammatory action stimulated by LPS+HMGB1 and are hindered by advanced glycation end products2023

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[Journal Article] Nordihydroguaiaretic acid inhibits glyoxalase I, and causes the accumulation of methylglyoxal followed by cell-growth inhibition2022

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[Journal Article] Identification of ribosomal protein L9 as a novel regulator of proinflammatory damage-associated molecular pattern molecules2022

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[Journal Article] 終末糖化産物AGEsは，IL-17A共存下において破骨細胞の分化を亢進する．2021

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NAID

Data Source

[Journal Article] グルタチオンS-トランスフェラーゼとグルタチオンとの相互作用をモデルとした示差走査蛍光定量法による分子間相互作用の解析に関する検討2021

Author(s)

Journal Title

Watanabe Masahiro 渡邊政博