AMANO IZUKI 天野出月

… Alternative Names

Amano Izuki 天野出月

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Researcher Number	10765275
Other IDs
Affiliation (Current)	2025: 群馬大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 群馬大学, 大学院医学系研究科, 准教授 2019 – 2022: 群馬大学, 大学院医学系研究科, 講師 2021: 群馬大学, 医学(系)研究科(研究院), 講師
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related Except Principal Investigator Basic Section 48020:Physiology-related
Keywords	Principal Investigator SMRT / 自閉症スペクトラム障害 / NCoR1 / 甲状腺ホルモン / 脳発達 / 抑制型転写共役因子 / NCoR / 発達障害 / 転写共役因子 / NCoR2 … More / 転写抑制型共役因子 / 小脳 / 小脳プルキンエ細胞 / 神経発達障害 / 脳腸相関 / 腸脳相関 / 低血糖 / グルコース輸送体 / 神経発達 / 抑制型転写抑制因子 / 社会性行動 / 認知学習機能 / 自閉症 … More Except Principal Investigator 高次脳機能 / 脳発達 / 甲状腺ホルモン Less

The mechanism of thyroid hormone action via the nuclear receptor corepressor (SMRT) in neurodevelopmentPrincipal Investigator
- Principal Investigator
  
  天野出月
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Gunma University
Mechanisms of thyroid hormone action on the development of higher brain function.
- Principal Investigator
  
  鯉淵典之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Gunma University
脳腸相関からみた抑制型転写共役因子の自閉症スペクトラム障害発症メカニズムの解明Principal Investigator
- Principal Investigator
  
  天野出月
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Gunma University
The role of nuclear corepressors in cerebellum and thyroid hormone actionPrincipal Investigator
- Principal Investigator
  
  Amano Izuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Gunma University
Corepressor Regulation of Thyroid Hormone Action in central nervous systemPrincipal Investigator
- Principal Investigator
  
  Amano Izuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Gunma University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] A Versatile, Behavioral Method to Investigate Thyroid Hormone Effects on Cerebellar Function2023
- Author(s)
  Ninomiya Ayane、Amano Izuki、Koibuchi Noriyuki
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 6 Issue: 200 Pages: 200-200
- DOI
  10.3791/65940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15340
[Journal Article] Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis2021
- Author(s)
  Ritter Megan J.、Amano Izuki、Imai Norihiro、Soares De Oliveira Lorraine、Vella Kristen R.、Hollenberg Anthony N.
- Journal Title
  
  Molecular Metabolism
  
  Volume: 53 Pages: 101315-101315
- DOI
  10.1016/j.molmet.2021.101315
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16486, KAKENHI-PROJECT-21K15340
[Journal Article] The Role of Thyroid Hormone in the Regulation of Cerebellar Development2021
- Author(s)
  Ishii Sumiyasu、Amano Izuki、Koibuchi Noriyuki
- Journal Title
  
  Endocrinology and Metabolism
  
  Volume: 36 Issue: 4 Pages: 703-716
- DOI
  10.3803/enm.2021.1150
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16486, KAKENHI-PROJECT-18H03379, KAKENHI-PROJECT-21K08569, KAKENHI-PROJECT-21K15340
[Journal Article] Absence of thyroid hormone induced delayed dendritic arborization in mouse primary hippocampal neurons through insufficient expression of brain-derived neurotrophic factor.2021
- Author(s)
  Hiroyuki Yajima, Izuki Amano, Sumiyasu Ishii, Tetsushi Sadakata, Wataru Miyazaki, Yusuke Takatsuru, Noriyuki Koibuchi.
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 12 Pages: 1-13
- DOI
  10.3389/fendo.2021.629100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06900, KAKENHI-PROJECT-20K23265, KAKENHI-PROJECT-19K16486, KAKENHI-PROJECT-21K15340
[Journal Article] Thyroid Hormone Signaling and the Liver.2020
- Author(s)
  Ritter MJ, Amano I, Hollenberg AN.
- Journal Title
  
  Hepatology.
  
  Volume: - Issue: 2 Pages: 742-752
- DOI
  10.1002/hep.31296
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16486
[Journal Article] Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action2019
- Author(s)
  Hiroaki Shimizu, Yu Lu, Kristen R. Vella, Federico Damilano, Inna Astapova, Izuki Amano, Megan Ritter, Molly R. Gallop, Anthony N. Rosenzweig, Ronald N. Cohen, Anthony N. Hollenberg
- Journal Title
  
  PLOS ONE
  
  Volume: Aug 12;14(8):e0220717 Issue: 8 Pages: 1-18
- DOI
  10.1371/journal.pone.0220717
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08486, KAKENHI-PROJECT-19K16486
[Presentation] The nuclear receptor corepressor, silencing mediator of retinoid and thyroid hormone receptors (SMRT), play unique roles in cerebellar Purkinje cells2024
- Author(s)
  天野出月、二ノ宮　彩音、小尾紀翔、Megan Ritter、 Anthony Hollenberg、鯉淵典之
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] Roles of the nuclear receptor corepressor 1 (NCoR1) and the silencing mediator of retinoid and thyroid hormone receptors (SMRT) in the developing brain2023
- Author(s)
  Izuki Amano, Ayane Ninomiya, Reika Kawabata-Iwakawa, Megan J. Ritter , Anthony N. Hollenberg, Noriyuki Koibuchi
- Organizer
  米国生理学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] 小脳プルキンエ細胞における抑制型転写共役因子NCoR2(SMRT)の役割の解明2023
- Author(s)
  天野出月、二ノ宮　彩音、小尾紀翔、Megan Ritter、 Anthony Hollenberg、鯉淵典之
- Organizer
  第66回日本甲状腺学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] The roles of the nuclear receptor corepressors in the mice central nervous system2023
- Author(s)
  Izuki Amano, Ayane Ninomiya, Reika Kawabata-Iwakawa, Megan J. Ritter , Anthony N. Hollenberg, Noriyuki Koibuchi
- Organizer
  第14回国際甲状腺不応症ワークショップ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] Role of the nuclear receptor corepressor 1 (NCoR1) and the silencing mediator of retinoid and thyroid hormone receptors (SMRT) on central nervous system2023
- Author(s)
  Izuki Amano, Ayane Ninomiya, Reika Kawabata-Iwakawa, Megan J. Ritter , Anthony N. Hollenberg, and Noriyuki Koibuchi
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] 抑制型転写共役因子NCoR1/SMRTの中枢神経系における役割の解明2022
- Author(s)
  天野出月、二ノ宮彩音、鯉淵典之
- Organizer
  第69回北関東医学総会
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] 抑制型転写共役因子Silencing mediator of retinoic acid and thyroid hormone receptorの脳発達における役割の解明2022
- Author(s)
  天野出月、二ノ宮　彩音、Megan Ritter, Kristen R. Vella, Anthony Hollenberg、鯉淵典之
- Organizer
  第95回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] マウスモデルを用いた中枢神経系における抑制型転写共役因子の役割の解明2021
- Author(s)
  天野出月、二ノ宮　彩音、Megan Ritter, Anthony Hollenberg、鯉淵典之
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] Nuclear receptor corepressors NCoR1 and SMRT plays unique roles in central nervous system2021
- Author(s)
  Izuki Amano Ayane Ninomiya , Megan Ritter , Kristen Vella , Anthony N. Hollenberg , Noriyuki Koibuchi
- Organizer
  ENDO2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] 小脳機能維持における甲状腺ホルモンの新規役割の解明：プルキンエ細胞小胞体からのカルシウム放出の調節における重要性2021
- Author(s)
  二ノ宮彩音、天野出月、小久保倫文、高鶴裕介、平井宏和、細井延武、鯉淵典之
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] The role of silencing mediator of retinoid and thyroid hormone receptors in the Purkinje cells2021
- Author(s)
  Izuki Amano , Ayane Ninomiya , Megan Ritter , Kristen R. Vella , Anthony N. Hollenberg, Noriyuki Koibuchi
- Organizer
  The 11th International Symposium of the Society for Research on the Cerebellum and Ataxias
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] The effect of lactational PFOS exposure on cerebellar function and motor coordination2021
- Author(s)
  Ayane Ninomiya, Abdallah Mshaty, Asahi Haijima, Hiroyuki Yajima, Michifumi Kokubo, Miski Aghnia Khairinisa, Winda Ariyani, Yuki Fujiwara, Sumiyasu Ishii, Nobutake Hosoi, Hirokazu Hirai, Izuki Amano, Noriyuki Koibuchi
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] The effects of nuclear corepressors in thyroid hormone action on brain development2021
- Author(s)
  Izuki Amano, Ayane Ninomiya, Megan Ritter, Kristen R. Vella, Anthony N. Hollenberg, Noriyuki Koibuchi
- Organizer
  第98回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] 脳発達における核内受容体コリプレッサー(SMRT)の役割2021
- Author(s)
  Izuki Amano Ayane Ninomiya , Megan Ritter , Kristen Vella , Anthony N. Hollenberg , Noriyuki Koibuchi
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] マウスモデルを用いた中枢神経系における抑制型転写共役因子の役割の解明2021
- Author(s)
  天野出月、二ノ宮　彩音、Megan Ritter, Kristen R. Vella, Anthony Hollenberg、鯉淵典之
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] The neurotoxic effect of lactational PFOS exposure on cerebellar functional development in adult male mice2021
- Author(s)
  Ayane Ninomiya, Abdallah Mshaty, Asahi Haijima, Hiroyuki Yajima, Michifumi Kokubo, Miski Aghnia Khairinisa, Winda Ariyani, Yuki Fujiwara, Sumiyasu Ishii, Nobutake Hosoi, Hirokazu Hirai, Izuki Amano, Noriyuki Koibuchi
- Organizer
  The 11th International Symposium of the Society for Research on the Cerebellum and Ataxias
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] Nuclear receptor corepressors NCoR1 and SMRT plays unique roles in central nervous system2021
- Author(s)
  Izuki Amano Ayane Ninomiya , Megan Ritter , Kristen Vella , Anthony N. Hollenberg , Noriyuki Koibuchi
- Organizer
  ENDO2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] 脳発達における核内受容体コリプレッサー(SMRT)の役割2021
- Author(s)
  Izuki Amano Ayane Ninomiya , Megan Ritter , Kristen Vella , Anthony N. Hollenberg , Noriyuki Koibuchi
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] The role of silencing mediator of retinoid and thyroid hormone receptors in the Purkinje cells2021
- Author(s)
  Izuki Amano , Ayane Ninomiya , Megan Ritter , Kristen R. Vella , Anthony N. Hollenberg, Noriyuki Koibuchi
- Organizer
  The 11th International Symposium of the Society for Research on the Cerebellum and Ataxias
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] Nuclear receptor corepressors NCoR1 and SMRT plays unique roles in central nervous system2021
- Author(s)
  Izuki Amano, Ayane Ninomiya, Megan Ritter, Kristen R. Vella, Anthony N. Hollenberg, Noriyuki Koibuchi
- Organizer
  ENDO 2021 annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] The effect of lactational PFOS exposure on cerebellar function and motor coordination2021
- Author(s)
  Ayane Ninomiya, Abdallah Mshaty, Asahi Haijima, Hiroyuki Yajima, Michifumi Kokubo, Miski Aghnia Khairinisa, Winda Ariyani, Yuki Fujiwara, Sumiyasu Ishii, Nobutake Hosoi, Hirokazu Hirai, Izuki Amano, Noriyuki Koibuchi
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] 中枢神経系における抑制型転写共役因子Silencing mediator of retinoic acid and thyroid hormone receptorの生理的機能の解明2021
- Author(s)
  天野出月、二ノ宮　彩音、Megan Ritter, Kristen R. Vella, Anthony Hollenberg、鯉淵典之
- Organizer
  第64回日本甲状腺学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] 小脳機能維持における甲状腺ホルモンの新規役割の解明：プルキンエ細胞小胞体からのカルシウム放出の調節における重要性2021
- Author(s)
  二ノ宮彩音、天野出月、小久保倫文、高鶴裕介、平井宏和、細井延武、鯉淵典之
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15340
[Presentation] 中枢神経系における抑制型転写共役因子Silencing mediator of retinoic acid and thyroid hormone receptorの生理的機能の解明2021
- Author(s)
  天野出月、二ノ宮　彩音、Megan Ritter, Kristen R. Vella, Anthony Hollenberg、鯉淵典之
- Organizer
  第64回日本甲状腺学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] The neurotoxic effect of lactational PFOS exposure on cerebellar functional development in adult male mice2021
- Author(s)
  Ayane Ninomiya, Abdallah Mshaty, Asahi Haijima, Hiroyuki Yajima, Michifumi Kokubo, Miski Aghnia Khairinisa, Winda Ariyani, Yuki Fujiwara, Sumiyasu Ishii, Nobutake Hosoi, Hirokazu Hirai, Izuki Amano, Noriyuki Koibuchi
- Organizer
  The 11th International Symposium of the Society for Research on the Cerebellum and Ataxias
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] Effects of chronic iodine excess on brain function2020
- Author(s)
  Izuki Amano, Yusuke Takatsuru, Shogo Haraguchi, Noriyuki Koibuchi
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] マウスモデルを用いた中枢神経系における転写共役因子の役割の解明2020
- Author(s)
  天野出月、鯉淵典之
- Organizer
  第67回北関東医学会総会
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] Nuclear Corepressor; SMRT Acts as an Important Regulator for Both Beta-Oxidation and the Maturation of Myogenesis in Mouse C2C12 Cell2020
- Author(s)
  Hiroaki Shimizu, Yasuhiro Horibata, Chieko Aoyama, Izuki Amano, Megan Ritter, Hiromi Ando, Hiroyuki Sugimoto, Anthony Neil Hollenberg
- Organizer
  ENDO annual meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] The Impact of Chronic Excess Iodine Intake in Adult Mice Behavior2020
- Author(s)
  Izuki Amano, Yusuke Takatsuru, Asahi Haijima, Shogo Haraguchi, Noriyuki Koibuchi
- Organizer
  ENDO annual meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] The role of thyroid hormone and nuclear corepressors on brain development and function2020
- Author(s)
  Izuki Amano, Ayane Ninomiya, Megan Ritter, Kristen R. Vella, Anthony N. Hollenberg, Noriyuki Koibuchi
- Organizer
  第63回日本甲状腺学会学術総会国際分子甲状腺シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] 周産期中等度甲状腺機能低下が協調運動機能に与える影響2019
- Author(s)
  小久保倫文1, 天野出月, 宮崎航, 高鶴裕介, 配島旭, 原口省吾, 鯉淵典之
- Organizer
  第62回日本甲状腺学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] マウスモデルを用いた慢性ヨウ素摂取過剰による脳発達への影響の解明2019
- Author(s)
  天野出月, 高鶴裕介, 蓜島旭, 亀尾聡美, 原口省吾, 鯉淵典之
- Organizer
  第62回日本甲状腺学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16486
[Presentation] 慢性的なヨウ素摂取過剰による脳高次機能への影響2019
- Author(s)
  天野出月, 高鶴裕介, 蓜島旭, 亀尾聡美, 原口省吾, 鯉淵典之
- Organizer
  第93回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16486

1. 鯉淵典之 (80234681)

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2. 藤原悠基 (20881220)

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3. 永田紀翔 (90975369)

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4. 清水裕晶

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5. 定方哲史

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AMANO IZUKI 天野 出月

Amano Izuki 天野 出月

Research Projects

Research Products

Co-Researchers

The mechanism of thyroid hormone action via the nuclear receptor corepressor (SMRT) in neurodevelopmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of thyroid hormone action on the development of higher brain function.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳腸相関からみた抑制型転写共役因子の自閉症スペクトラム障害発症メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of nuclear corepressors in cerebellum and thyroid hormone actionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Corepressor Regulation of Thyroid Hormone Action in central nervous systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] A Versatile, Behavioral Method to Investigate Thyroid Hormone Effects on Cerebellar Function2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Role of Thyroid Hormone in the Regulation of Cerebellar Development2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Absence of thyroid hormone induced delayed dendritic arborization in mouse primary hippocampal neurons through insufficient expression of brain-derived neurotrophic factor.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thyroid Hormone Signaling and the Liver.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] The nuclear receptor corepressor, silencing mediator of retinoid and thyroid hormone receptors (SMRT), play unique roles in cerebellar Purkinje cells2024

Author(s)

Organizer

Data Source

[Presentation] Roles of the nuclear receptor corepressor 1 (NCoR1) and the silencing mediator of retinoid and thyroid hormone receptors (SMRT) in the developing brain2023

Author(s)

Organizer

Data Source

[Presentation] 小脳プルキンエ細胞における抑制型転写共役因子NCoR2(SMRT)の役割の解明2023

Author(s)

Organizer

Data Source

[Presentation] The roles of the nuclear receptor corepressors in the mice central nervous system2023

Author(s)

Organizer

AMANO IZUKI 天野出月

Amano Izuki 天野出月