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Okubo Makiko  大久保 牧子

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OKUBO Makiko  大久保 牧子

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Researcher Number 10780611
Affiliation (Current) 2025: 横浜市立大学, 医学研究科, 客員研究員
Affiliation (based on the past Project Information) *help 2016 – 2023: 横浜市立大学, 医学研究科, 客員研究員
Review Section/Research Field
Principal Investigator
Basic Section 57060:Surgical dentistry-related / Surgical dentistry
Keywords
Principal Investigator
口腔癌 / M2マクロファージ / オルガノイド / マクロファージ / がん再発 / 口腔癌オルガノイド / 口腔がんオルガノイド / 歯学 / PD-1/PD-L1 / PD-L1 … More / PD-1 / 骨髄由来細胞 / 放射線照射 / 再発口腔癌 Less
  • Research Projects

    (4 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (3 People)
  •  The role of M2 macrophage associated with treatment resistance in oral cancer and establishment of therapeutic strategyPrincipal Investigator

    • Principal Investigator
      大久保 牧子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Yokohama City University
  •  identification of M2 macrophage-secreted factors involved in oral cancer relapsePrincipal Investigator

    • Principal Investigator
      OKUBO Makiko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Yokohama City University
  •  Analysis of M2 macrophage functions in recurrence of oral cancerPrincipal Investigator

    • Principal Investigator
      OKUBO Makiko
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Yokohama City University
  •  Development of anti-PD-1/PD-L1 therapy targeting tumor microenvironment for oral cancerPrincipal Investigator

    • Principal Investigator
      OKUBO Makiko
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Surgical dentistry
    • Research Institution
      Yokohama City University

All 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] M2-polarized macrophages contribute to neovasculogenesis, leading to recurrence of oral cancer after radiation2018

    • Author(s)
      大久保牧子・來生 知_杉浦 圭・光藤健司・藤内 祝
    • Journal Title

      Japanese Journal of Oral and Maxillofacial Surgery

      Volume: 64 Issue: 5 Pages: 307-320

    • DOI

      10.5794/jjoms.64.307

    • NAID

      130007399807

    • ISSN
      0021-5163, 2186-1579
    • Year and Date
      2018-05-20
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K17233
  • [Journal Article] M2-polarized macrophages contribute to neovasculogenesis, leading to relapse of oral cancer following radiation.2016

    • Author(s)
      Okubo M, Kioi M, Nakashima H, Sugiura K, Mitsudo K, Aoki I, Taniguchi H, Tohnai I.
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 27548-27548

    • DOI

      10.1038/srep27548

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293431, KAKENHI-PROJECT-16H07108
  • [Presentation] 放射線照射後の癌微小環境ニッチにおける骨髄細胞の役割2017

    • Author(s)
      大久保牧子
    • Organizer
      第71回日本口腔科学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H07108
  • [Presentation] 口腔癌の放射線治療後の再発に関わる骨髄CD11b陽性単球細胞の役割とメカニズムの解明2017

    • Author(s)
      大久保牧子
    • Organizer
      第35回日本口腔腫瘍学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-16H07108
  • [Presentation] 口腔癌再発に関わる骨髄CD11b陽性単球細胞の役割とバイオマーカーとしての検討2017

    • Author(s)
      大久保牧子
    • Organizer
      第41回日本頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-16H07108
  • [Presentation] 口腔癌再発を導く骨髄CD11b+単球細胞の分化機構とその役割2016

    • Author(s)
      大久保牧子
    • Organizer
      第61回日本口腔外科学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-16H07108
  • 1.  來生 知 (30545059)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  谷口 英樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  藤内 祝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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