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Kawashima Akihiro  川嶋 章弘

… Alternative Names

KAWASHIMA AKIHIRO  川嶋 章弘

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Researcher Number 10783376
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-3501-4854
Affiliation (Current) 2025: 昭和大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2019 – 2025: 昭和大学, 医学部, 講師
2016 – 2018: 昭和大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Embryonic/Neonatal medicine / Basic Section 52050:Embryonic medicine and pediatrics-related
Except Principal Investigator
Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 57020:Oral pathobiological science-related
Keywords
Principal Investigator
胎児治療 / 脂肪組織由来幹細胞 / ダウン症 / 再生医療 / 妊娠初期絨毛 / メチル化異常 / エピゲノム / 初期絨毛 / DNAメチル化 / cell-free DNA … More / 妊娠初期 / 胎盤幹細胞 / メチル化 / 妊娠高血圧腎症 / 精神神経発達遅滞 / 間葉系幹細胞 / 脳疾患 / 神経誘導 / 胎児幹細胞治療 / 幹細胞治療 / 脂肪由来間葉系幹細胞 / 脳機能障害 / 先天代謝異常症 / 脳神経疾患 / 先天性代謝疾患 / 幹細胞 … More
Except Principal Investigator
妊娠高血圧腎症 / 遺伝子 / DNAメチル化 / 妊娠高血圧症候群 / 遺伝 / アスピリン抵抗性 / アスピリン / シグナル伝達 / エキソソーム / 亜鉛トランスポーター / 骨格成長 / 細胞・組織 / 軟骨 / 骨格形成 / 血液型 / ゲノム / 血液型不適合妊娠 / RHD / 出生前診断 / 血液型不適合姙娠 / RhD / 絨毛検査 / 妊娠初期絨毛 / 妊娠高血圧症侯群 / 絨毛細胞 / 胎盤 / 絨毛 / 卵巣癌 / 子宮頸癌 / 子宮体癌 / 遺伝子産物 / 癌バイオマーカー / 腫瘍マーカー / 染色体不安定性 / CNV / 婦人科悪性腫瘍 / MPS法 / cell free DNA Less
  • Research Projects

    (11 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (15 People)
  •  ADORA2B抑制による胎盤幹細胞の酸化ストレス応答とPE予防戦略の開発Principal Investigator

    • Principal Investigator
      川嶋 章弘
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Showa University
  •  Elucidation of the pathogenasis and the development of prevention and treatment of preeclampsia through genetic analysis of aspirin resistance

    • Principal Investigator
      金子 真由美 (徳中真由美)
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Showa University
  •  Epigenetic Approaches for the Elucidation of Preeclampsia Development Mechanisms in Primary PlacentaPrincipal Investigator

    • Principal Investigator
      川嶋 章弘
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Showa University
  •  Development a method to predict preeclampsia using maternal plasma DNA/RNA

    • Principal Investigator
      Koide Keiko
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Showa University
  •  Development of the fetal therapy using maternal adipose-derived stem cellsPrincipal Investigator

    • Principal Investigator
      Akihiro Kawashima
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Showa University
  •  The exploration of exosome involvement in skeletal abnormalities induced by dysregulation of zinc homeostasis

    • Principal Investigator
      Yasuhara Rika
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Showa University
  •  Pathophysiology of hypertensive disorder of pregnancy through DNA methylation analysis of villous trophoblasts in first trimester

    • Principal Investigator
      Sekizawa Akihiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Showa University
  •  日本人のRhD陰性の遺伝子型の探索:母体血からの胎児RhD血液型診断法の確立

    • Principal Investigator
      那須 美智子
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Showa University
  •  ENGRAFTMENT POTENTIAL OF MATERNAL ADIPOSE-DERIVED STEM CELLS FOR IN UTERO TRANSPLANTATIONPrincipal Investigator

    • Principal Investigator
      Kawashima Akihiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Showa University
  •  Adipose-tissue-derived stem cells could be an ideal cell source for neural regeneration when to treat a fetus in uteroPrincipal Investigator

    • Principal Investigator
      KAWASHIMA AKIHIRO
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Showa University
  •  Development of a novel biomarker using peripheral blood for detection of tumor derived chromosome instability

    • Principal Investigator
      Shimizu Hanako
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Showa University

All 2024 2023 2022 2020 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Engraftment potential of maternal adipose-derived stem cells for fetal transplantation2020

    • Author(s)
      Kawashima Akihiro、Yasuhara Rika、Akino Ryosuke、Mishima Kenji、Nasu Michiko、Sekizawa Akihiko
    • Journal Title

      Heliyon

      Volume: 6 Issue: 3 Pages: 1-9

    • DOI

      10.1016/j.heliyon.2020.e03409

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09540, KAKENHI-PROJECT-17K16311, KAKENHI-PROJECT-20K21688, KAKENHI-PROJECT-19H03827, KAKENHI-PROJECT-19K17378
  • [Journal Article] Cytokine profiles in maternal serum are candidates for predicting an optimal timing for the delivery in early‐onset fetal growth restriction2020

    • Author(s)
      Kawashima Akihiro、Oba Tomohiro、Yasuhara Rika、Sekiya Bunbu、Sekizawa Akihiko
    • Journal Title

      Prenatal Diagnosis

      Volume: Epub Issue: 6 Pages: 728-737

    • DOI

      10.1002/pd.5679

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09540, KAKENHI-PROJECT-17K16311, KAKENHI-PROJECT-19K17378
  • [Journal Article] Amplicon Sequencing-Based Noninvasive Fetal Genotyping for RHD-Positive D Antigen-Negative Alleles2019

    • Author(s)
      Takahashi Ken、Migita Ohsuke、Sasaki Aiko、Nasu Michiko、Kawashima Akihiro、Sekizawa Akihiko、Sato Taisuke、Ito Yuki、Sago Haruhiko、Okamoto Aikou、Nakabayashi Kazuhiko、Hata Kenichiro
    • Journal Title

      Clinical Chemistry

      Volume: 65 Issue: 10 Pages: 1307-1316

    • DOI

      10.1373/clinchem.2019.307074

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01588, KAKENHI-PROJECT-17K16311, KAKENHI-PROJECT-18H03556
  • [Journal Article] Generation of orthotopically functional salivary gland from embryonic stem cells2018

    • Author(s)
      Tanaka Junichi、Ogawa Miho、Hojo Hironori、Kawashima Yusuke、Mabuchi Yo、Hata Kenji、Nakamura Shiro、Yasuhara Rika、Takamatsu Koki、Irie Tarou、Fukada Toshiyuki、Sakai Takayoshi、Inoue Tomio、Nishimura Riko、Ohara Osamu、Saito Ichiro、Ohba Shinsuke、Tsuji Takashi、Mishima Kenji
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 4216-4216

    • DOI

      10.1038/s41467-018-06469-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11488, KAKENHI-PROJECT-18K09540, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-17H04011, KAKENHI-PROJECT-17H04373, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-15K06853, KAKENHI-PROJECT-16K11459, KAKENHI-PROJECT-15K15737, KAKENHI-PROJECT-17K19775, KAKENHI-PROJECT-17K17088, KAKENHI-PROJECT-15H02575
  • [Journal Article] Massively parallel sequencing of cell-free DNA in plasma for detecting gynaecological tumour-associated copy number alteration.2018

    • Author(s)
      Nakabayashi M, Kawashima A, Yasuhara R, Hayakawa Y, Miyamoto S, Iizuka C, Sekizawa A.
    • Journal Title

      Sci Rep.

      Volume: 8(1):15883 Issue: 1 Pages: 1-12

    • DOI

      10.1038/s41598-018-34168-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09540
  • [Presentation] Early onset preeclampsia is associated with altered DNA methylation in the first trimester villi2024

    • Author(s)
      Akihiro Kawashima
    • Organizer
      2024 Annual Congress of Taiwan Association of Obstetrics and Gynecology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09551
  • [Presentation] Knockdown of Adora2b accelerates ferroptosis in placental stem cells2023

    • Author(s)
      Akihiro Kawashima
    • Organizer
      第75回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-21K09551
  • [Presentation] 妊娠高血圧腎症の発症につながる妊娠初期絨毛の  機能変化についての検討2022

    • Author(s)
      Akihiro Kawashima
    • Organizer
      第74回日本産科婦人科学術集会 シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K09551
  • [Presentation] In utero transplantation with organoid of mesenchymal stem cell-derived neural progenitor2020

    • Author(s)
      Akihiro Kawashima
    • Organizer
      第72回日本産婦人科学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K17378
  • [Presentation] Each negative alteration in early-onset fetal growth restriction changes the profile of maternal serum cytokines into a peculiar feature. We want to explore this further as an early warning system.2019

    • Author(s)
      Akihiro Kawashima
    • Organizer
      the 24th International Conference on Prenatal Diagnosis and Therapy.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16311
  • [Presentation] Loss of ZIP10 impairs skeletal development via osteochondrocyte functions.2019

    • Author(s)
      Rika Yasuhara, Akihiro Kawashima, Akane Yukimori, Junichi Tanaka, Satoko Kujiraoka, Toshiyuki Fukada, Motomi Enomoto-Iwamoto, Kenji Mishima
    • Organizer
      ASBMR 2019 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09540
  • [Presentation] THE ENGRAFTMENT POTENTIAL OF MATERNAL ADIPOSE-DERIVED STEM CELLS, FOR FETAL TRANSPLANTATION2019

    • Author(s)
      Akihiro Kawashima
    • Organizer
      日本産科婦人科学会
    • Data Source
      KAKENHI-PROJECT-17K16311
  • [Presentation] The Engraftment potential of maternal adipose-derived stem cells for fetal transplantation2019

    • Author(s)
      Akihiro Kawashima
    • Organizer
      International Society for Stem Cell Research 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16311
  • [Presentation] Each negative alteration in early-onset fetal growth restriction changes the profile of maternal serum cytokines into a peculiar feature. We want to explore this further as an early warning system.2019

    • Author(s)
      Akihiro Kawashima
    • Organizer
      the 24th International Conference on Prenatal Diagnosis and Therapy.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17378
  • [Presentation] The Engraftment potential of maternal adipose-derived stem cells for fetal transplantation2019

    • Author(s)
      Akihiro Kawashima
    • Organizer
      International Society for Stem Cell Research 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17378
  • [Presentation] Engraftment potential of maternal adipose-derived stem cells for fetal transplantation2019

    • Author(s)
      Akihiro Kawashima
    • Organizer
      The 72nd Annual Congress of JSOG
    • Data Source
      KAKENHI-PROJECT-19K17378
  • [Presentation] Engraftment potential of maternal adipose-derived stem cells for fetal transplantation2019

    • Author(s)
      Akihiro Kawashima
    • Organizer
      The 72nd Annual Congress of JSOG
    • Data Source
      KAKENHI-PROJECT-17K16311
  • [Presentation] Exploration of the use of adipose tissue-derived stem cells for in utero transplantation2018

    • Author(s)
      Akihiro Kawashima
    • Organizer
      International society for stem cell research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16311
  • [Presentation] Development of a novel biomarker for neoplasms through analysis of copy number variations in cell-free DNA of the blood of patients.2017

    • Author(s)
      Makoto Nakabayashi, Akihito Kawashima, Akihiko Sekizawa
    • Organizer
      日本産科婦人科学会第69回学術講演会
    • Place of Presentation
      広島
    • Year and Date
      2017-04-14
    • Data Source
      KAKENHI-PROJECT-15K15612
  • [Presentation] Adipose-derived-mesenchymal stem cells could be a promising cell source of tissue regeneration in congenital neural degeneration2017

    • Author(s)
      川嶋章弘
    • Organizer
      第69回日本産科婦人科学会学術講演会
    • Place of Presentation
      広島県立総合体育館
    • Year and Date
      2017-04-13
    • Data Source
      KAKENHI-PROJECT-16H07193
  • [Presentation] 子宮内胎仔脳室内投与における脂肪組織由来幹細胞の中枢神経系への有効性2017

    • Author(s)
      川嶋章弘
    • Organizer
      第39回分子生物学会
    • Data Source
      KAKENHI-PROJECT-17K16311
  • [Presentation] MOUSE ADIPOSE TISSUE-DERIVED STEM CELLS COULD BE AN IDEAL SOURCE FOR IN UTERO THERAPEUTIC REPAIR OF FETAL BRAIN DYSFUNCTION2017

    • Author(s)
      川嶋章弘
    • Organizer
      ISSCR 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16311
  • [Presentation] 子宮内胎仔脳室内投与における脂肪組織由来幹細胞の中枢神経系への有効性2016

    • Author(s)
      川嶋章弘
    • Organizer
      第39回分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16H07193
  • 1.  Sekizawa Akihiko (10245839)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 2.  Shimizu Hanako (20551203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  Yasuhara Rika (20453649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  Koide Keiko (90384437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  四元 淳子 (30553648)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  那須 美智子 (00750457)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  青木 弘子 (60465127)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  田中 準一 (40710166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  美島 健二 (50275343)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  金子 真由美 (10643710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  細沼 雅弘 (20836457)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  NAKABAYASHI Makoto
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  井上 富雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  中村 史朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  中林 一彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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