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iguchi tomohiro  井口 智弘

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IGUCHI Tomohiro  井口 智弘

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Researcher Number 10783516
Other IDs
Affiliation (Current) 2025: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主任研究員
Affiliation (based on the past Project Information) *help 2020 – 2023: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 43010:Molecular biology-related
Except Principal Investigator
Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Keywords
Principal Investigator
細胞分化 / ASK / Cdc7 / DNA replication / サイクリン依存性キナーゼ / RIF1 / 血球系細胞 / 脳形成 / DNA複製 / Cdc7-ASKキナーゼ … More
Except Principal Investigator
… More G-quadruplexes / クライオ電顕 / グアニン4重鎖 / シェルタリン / テロメア / クロマチンループ / 単粒子解析 / 電子顕微鏡 / グアニン四重鎖 / オリゴマー / Rif1 Less
  • Research Projects

    (2 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (3 People)
  •  Elucidation of the function of Cdc7-ASK(Dbf4) kinases in vivoPrincipal Investigator

    • Principal Investigator
      IGUCHI Tomohiro
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43010:Molecular biology-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  On-grid biochemistry: Structural analyses of G-quadruplex-telomere factor complexes

    • Principal Investigator
      正井 久雄
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science

All 2024 2023 2021 2020

All Journal Article Presentation

  • [Journal Article] Homologous recombination contributes to the repair of acetaldehyde-induced DNA damage2024

    • Author(s)
      Yamazaki Kosuke、Iguchi Tomohiro、Kanoh Yutaka、Takayasu Kazuto、Ngo Trinh Thi To、Onuki Ayaka、Kawaji Hideya、Oshima Shunji、Kanda Tomomasa、Masai Hisao、Sasanuma Hiroyuki
    • Journal Title

      Cell Cycle

      Volume: 3 Issue: 4 Pages: 1-16

    • DOI

      10.1080/15384101.2024.2335028

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20KK0157, KAKENHI-PUBLICLY-22H04707
  • [Journal Article] Cdc7 kinase is required for postnatal brain development2023

    • Author(s)
      Hori Karin、Yamazaki Satoshi、Ohtaka‐Maruyama Chiaki、Ono Tomio、Iguchi Tomohiro、Masai Hisao
    • Journal Title

      Genes to Cells

      Volume: 28 Issue: 10 Pages: 679-693

    • DOI

      10.1111/gtc.13059

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20KK0157, KAKENHI-PUBLICLY-22H04707, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H04925
  • [Presentation] Regulation of replication timing and DNA repair by nuclear membrane tethering of Rif12023

    • Author(s)
      Hisao Masai, Tomohiro Iguchi, Sayuri Ito, Mikihiro Shibata, Naoko Kakusho, Rino Fukatsu, Asami Oji, Ichiro Hiratani, Hiroyuki Sasanuma
    • Organizer
      The 14th International Symposium on DNA Damage Response & Human Disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20KK0157
  • [Presentation] マウスのCD4+T細胞における転写制御と分化におけるClaspinの役割2023

    • Author(s)
      蕭 皓文、井口 智弘 、笹沼 博之、正井 久雄
    • Organizer
      第46回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20KK0157
  • [Presentation] Neural stem cell- or Hematopoietic stem cell-specific knockout of Cdc7 or ASK(Dbf4) causes common and distinct phenotypes2023

    • Author(s)
      Tomohiro Iguchi, Karin Hori, Satoshi Yamazaki, Rie Ishii, Hiroyuki Sasanuma, Hisao Masai, Iguchi, T.
    • Organizer
      Cold Spring Harbor Laboratory Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20KK0157
  • [Presentation] Association of Rif1 with nuclear membrane is essential for genome-wide replication timing regulation2023

    • Author(s)
      Tomohiro Iguchi, Sayuri Ito, Naoko Kakusho, Rino Fukatsu, Kenji Moriyama, Asako Sawano, Asami Oji, Mikihiro Shibata, Atsushi Miyawaki, Ichiro Hiratani, Hiroyuki Sasanuma and Hisao Masai
    • Organizer
      CSHL Meeting 2023 on Eukaryotic DNA Replication & Genome Maintenance
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20KK0157
  • [Presentation] Functions associated with the long IDP segment of Rif1, a regulator of replication timing, DSB repair and chromatin architecture2023

    • Author(s)
      Bingyi Li, Kosuke Yamazaki, Tomohiro Iguchi, Hiroyuki Sasanuma, Hisao Masai
    • Organizer
      第46回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20KK0157
  • [Presentation] 染色体DNA複製開始複合体と開始制御メカニズムの新たな展望2023

    • Author(s)
      Hisao Masai, Taku Tanaka, Tomohiro Iguchi, Sayuri Ito, Naoko Kakusho, Rino Fukatsu, Yutaka Kanoh, Tomoko Sagi, and Hiroyuki Sasanuma
    • Organizer
      第96回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20KK0157
  • [Presentation] 染色体動態・維持・機能を決定する多様な因子2023

    • Author(s)
      井口 智弘、伊藤 さゆり、覺正 直子、深津 理乃、森山 賢治、坂上-沢野 朝子、大字 亜沙美、柴田 幹大、宮脇 敦史、平谷 伊智朗、笹沼 博之、正井 久雄
    • Organizer
      第46回 日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20KK0157
  • [Presentation] Mechanisms of membrane association of Rif1 and its role in replication timing regulation2021

    • Author(s)
      Tomohiro Iguchi, Sayuri Ito, Naoko Kokusho, Yutaka Kanoh, Kaho, Takasawa, Kenji Moriyama, Hiroyuki Sasanuma, Hisao Masai.
    • Organizer
      Cold Spring Harbor Laboratory Meeting EUKARYOTIC DNA REPLICATION & GENOME MAINTENANCE
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20KK0157
  • [Presentation] Association of Rif1 with nuclear membrane is essential for genome-wide replication timing regulation2021

    • Author(s)
      Tomohiro Iguchi, Sayuri Ito, Naoko Kakusho, Satoshi Yamazaki, Asami Oji, Rino Fukatsu, Ichiro Hiratani, Hiroyuki Sasanuma, Hisao Masai
    • Organizer
      第44回日本分子生物学会年会 シンポジウム 「DNA構造ダイナミクスを基盤とするゲノム複製と維持の生物種を超えた共通原理」
    • Invited
    • Data Source
      KAKENHI-PROJECT-20KK0157
  • [Presentation] The activation subunit of Cdc7, ASK(Dbf4), but not Cdc7 catalytic subunit, is essential for immune cell proliferation and differentiation2021

    • Author(s)
      Tomohiro Iguchi, Satoshi Yamazaki, Tomio Ono, Rie Ishii, Karin Hori, Shunsuke Kobayashi, Hisao Masai
    • Organizer
      2021年度 先端モデル動物支援 若手支援技術講習会
    • Data Source
      KAKENHI-PROJECT-20K15725
  • [Presentation] The activation subunit of Cdc7, ASK(Dbf4), but not Cdc7 catalytic subunit, is es sential for immune cell proliferation and differentiation2021

    • Author(s)
      Tomohiro Iguchi, Satoshi Yamazaki, Tomio Ono, Rie Ishii, Karin Hori, Shunsuke Kobayashi, Hisao Masai
    • Organizer
      第44回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K15725
  • [Presentation] Roles of Cdc7 and its activation subunit ASK(Dbf4) in immune cell proliferation and differentiation2020

    • Author(s)
      Tomohiro Iguchi, Satoshi Yamazaki, Tomio Ono, Rie Ishii, Karin Hori, Shunsuke Kobayashi, Hisao Masai
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K15725
  • [Presentation] Roles of Cdc7-ASK kinase complex in brain development2020

    • Author(s)
      Karin Hori, Tomohiro Iguchi, Satoshi Yamazaki, Tomio Ono, Chiaki Maruyama, Hisao Masai
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K15725
  • 1.  正井 久雄 (40229349)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 2.  森山 賢治 (00250217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  加納 豊 (90450593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results

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