Nishiguchi Akihiro 西口昭広

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NISHIGUCHI Akihiro 西口昭広

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Researcher Number	10784944
Other IDs	https://orcid.org/0000-0002-3160-6385
Affiliation (Current)	2025: 国立研究開発法人物質・材料研究機構, 高分子・バイオ材料研究センター, 主幹研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 国立研究開発法人物質・材料研究機構, 高分子・バイオ材料研究センター, 主幹研究員 2020 – 2022: 国立研究開発法人物質・材料研究機構, 機能性材料研究拠点, 主任研究員 2018 – 2019: 国立研究開発法人物質・材料研究機構, 機能性材料研究拠点, 研究員
Review Section/Research Field	Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90120:Biomaterials-related / Basic Section 28040:Nanobioscience-related
Keywords	Principal Investigator 組織再生 / 液-液相分離 / 生体適合性 / ハイドロゲル / ポリアミン / 免疫制御 / 再生医療 / 組織接着 / 超分子 / インジェクタブルゲル … More / ゲノム編集 / 相転移 / 癒着防止 / ナノ粒子 / 炎症性疾患 / 抗炎症 / 足場材料 / ナノバイオ界面 / 生体材料 / 疎水基 / バイオポリマー / 粒子 / 疎水性 / ナノーバイオ界面 / 生体高分子 / ゼラチン / 微粒子 / 創傷治癒 Less

ゲノム編集スキャフォールドによるin vivoダイレクトリプログラミングPrincipal Investigator
- Principal Investigator
  
  西口昭広
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  National Institute for Materials Science
Regulation of intestinal microenvironment networks by polyamine nanoparticles and its application to the treatment of inflammatory bowel diseasePrincipal Investigator
- Principal Investigator
  
  NISHIGUCHI Akihiro
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  National Institute for Materials Science
Development of hotmelt tissue adhesive based on controlling of sol-gel transitionPrincipal Investigator
- Principal Investigator
  
  西口昭広
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  National Institute for Materials Science
Development of immuno-suppressive scaffold for regenerative medicinePrincipal Investigator
- Principal Investigator
  
  NISHIGUCHI Akihiro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  National Institute for Materials Science
Development of wound dressing of hydrophobized colloids by controlling nano-bio interface functionsPrincipal Investigator
- Principal Investigator
  
  NISHIGUCHI Akihiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  National Institute for Materials Science

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] 組織接着剤2024
- Author(s)
  西口昭広、田口哲志
- Journal Title
  
  ハイドロゲル
  
  Volume: 1 Pages: 66-73
- Data Source
  KAKENHI-PROJECT-23K25216
[Journal Article] Injectable microcapillary network hydrogels engineered by liquid-liquid phase separation for stem cell transplantation2024
- Author(s)
  Nishiguchi Akihiro、Ito Shima、Nagasaka Kazuhiro、Komatsu Hiyori、Uto Koichiro、Taguchi Tetsushi
- Journal Title
  
  Biomaterials
  
  Volume: 305 Pages: 122451-122451
- DOI
  10.1016/j.biomaterials.2023.122451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K25216
[Journal Article] 生体機能化ポリマーによる免疫細胞機能制御2023
- Author(s)
  西口昭広、田口哲志
- Journal Title
  
  Drug Delivery System
  
  Volume: 38 Pages: 379-387
- Data Source
  KAKENHI-PROJECT-22K19947
[Journal Article] ゾル-ゲル転移制御によるホットメルト組織接着剤の創出2023
- Author(s)
  西口昭広、田口哲志
- Journal Title
  
  バイオマテリアル―生体材料―
  
  Volume: 41 Pages: 68-69
- Data Source
  KAKENHI-PROJECT-23K25216
[Journal Article] Inflammation-targeting polyamine nanomedicines for the treatment of ulcerative colitis2023
- Author(s)
  Nishiguchi Akihiro、Taguchi Tetsushi
- Journal Title
  
  Journal of Materials Chemistry B
  
  Volume: 11 Issue: 18 Pages: 4005-4013
- DOI
  10.1039/d3tb00424d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19947, KAKENHI-PROJECT-23K26411
[Journal Article] Tissue-Adhesive Decellularized Extracellular Matrix Patches Reinforced by a Supramolecular Gelator to Repair Abdominal Wall Defects2023
- Author(s)
  Nishiguchi Akihiro、Ito Shima、Nagasaka Kazuhiro、Taguchi Tetsushi
- Journal Title
  
  Biomacromolecules
  
  Volume: 24 Issue: 4 Pages: 1545-1554
- DOI
  10.1021/acs.biomac.2c01210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K25216, KAKENHI-PROJECT-23K26411
[Journal Article] ゾル-ゲル転移制御に基づくホットメルト型医療用接着剤の開発と癒着防止材への応用2023
- Author(s)
  西口昭広、田口哲志
- Journal Title
  
  Material Stage
  
  Volume: 23 Pages: 35-40
- Data Source
  KAKENHI-PROJECT-23K25216
[Journal Article] 組織接着性ハイドロゲルの設計と術後合併症予防への応用2023
- Author(s)
  西口昭広、田口哲志
- Journal Title
  
  バイオマテリアル―生体材料―
  
  Volume: 41-2 Pages: 102-104
- Data Source
  KAKENHI-PROJECT-23K25216
[Journal Article] Engineering thixotropic supramolecular gelatin-based hydrogel as an injectable scaffold for cell transplantation2022
- Author(s)
  Nishiguchi Akihiro、Taguchi Tetsushi
- Journal Title
  
  Biomedical Materials
  
  Volume: 18 Issue: 1 Pages: 015012-015012
- DOI
  10.1088/1748-605x/aca501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K25216
[Journal Article] 術後合併症を予防するホットメルト組織接着剤開発2022
- Author(s)
  西口昭広、田口哲志
- Journal Title
  
  月刊BIO INDUSTRY
  
  Volume: 39 Pages: 22-27
- Data Source
  KAKENHI-PROJECT-23K25216
[Journal Article] Liquid?Liquid Phase-Separated Hydrogel with Tunable Sol?Gel Transition Behavior as a Hotmelt-Adhesive Postoperative Barrier2022
- Author(s)
  Nishiguchi Akihiro、Ito Shima、Nagasaka Kazuhiro、Taguchi Tetsushi
- Journal Title
  
  ACS Applied Bio Materials
  
  Volume: 5 Issue: 10 Pages: 4932-4941
- DOI
  10.1021/acsabm.2c00640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02470, KAKENHI-PROJECT-23K25216
[Journal Article] Hotmelt tissue adhesive with supramolecularly-controlled sol-gel transition for preventing postoperative abdominal adhesion2022
- Author(s)
  Nishiguchi Akihiro、Ichimaru Hiroaki、Ito Shima、Nagasaka Kazuhiro、Taguchi Tetsushi
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 146 Pages: 80-93
- DOI
  10.1016/j.actbio.2022.04.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02470, KAKENHI-PROJECT-23K25216
[Journal Article] Oligoethyleneimine‐Conjugated Hyaluronic Acid Modulates Inflammatory Responses and Enhances Therapeutic Efficacy for Ulcerative Colitis2021
- Author(s)
  Nishiguchi Akihiro、Taguchi Tetsushi
- Journal Title
  
  Advanced Functional Materials
  
  Volume: 31 Issue: 30 Pages: 2100548-2100548
- DOI
  10.1002/adfm.202100548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20207, KAKENHI-PROJECT-20H02470
[Journal Article] Designing an anti-inflammatory and tissue-adhesive colloidal dressing for wound treatment2020
- Author(s)
  Nishiguchi Akihiro、Taguchi Tetsushi
- Journal Title
  
  Colloids and Surfaces B: Biointerfaces
  
  Volume: 188 Pages: 110737-110737
- DOI
  10.1016/j.colsurfb.2019.110737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14099
[Journal Article] Hemostatic, Tissue-Adhesive Colloidal Wound Dressing Functionalized by UV Irradiation2020
- Author(s)
  Nishiguchi Akihiro、Kurihara Yukari、Taguchi Tetsushi
- Journal Title
  
  ACS Applied Bio Materials
  
  Volume: 3 Issue: 3 Pages: 1705-1711
- DOI
  10.1021/acsabm.0c00015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14099
[Journal Article] 再生医療のためのバイオマテリアル2020
- Author(s)
  西口昭広
- Journal Title
  
  Precision Medicine
  
  Volume: 3 Pages: 55-60
- Data Source
  KAKENHI-PROJECT-20K20207
[Journal Article] Multifunctional Hydrophobized Microparticles for Accelerated Wound Healing after Endoscopic Submucosal Dissection2019
- Author(s)
  Nishiguchi Akihiro、Sasaki Fumisato、Maeda Hidehito、Kabayama Masayuki、Ido Akio、Taguchi Tetsushi
- Journal Title
  
  Small
  
  Volume: 15 Issue: 35 Pages: 1901566-1901566
- DOI
  10.1002/smll.201901566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14099
[Journal Article] Underwater-adhesive microparticle dressing composed of hydrophobically-modified Alaska pollock gelatin for gastrointestinal tract wound healing2019
- Author(s)
  Nishiguchi Akihiro、Kurihara Yukari、Taguchi Tetsushi
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 99 Pages: 387-396
- DOI
  10.1016/j.actbio.2019.08.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14099
[Patent] ゲル化剤、ゲル組成物、細胞足場材料、及び医療材料2023
- Inventor(s)
  西口昭広
- Industrial Property Rights Holder
  国立研究開発法人物質・材料研究機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-021379
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K25216
[Patent] ゲル化剤、インジェクタブルゲル、ゲル組成物、細胞足場材料、及び医療材料2023
- Inventor(s)
  西口昭広
- Industrial Property Rights Holder
  国立研究開発法人物質・材料研究機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-104805
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K25216
[Patent] 修飾ゼラチン、これを含む、組織接着剤、ハイドロゲル、薬物送達担体、フィルム、多孔体および血管塞栓剤、多孔体の製造方法2022
- Inventor(s)
  西口昭広
- Industrial Property Rights Holder
  国立研究開発法人物質・材料研究機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-125361
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-23K25216
[Patent] 組成物、及び接着剤2022
- Inventor(s)
  西口昭広
- Industrial Property Rights Holder
  国立研究開発法人物質・材料研究機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-074217
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] 液-液相分離制御による細胞移植用インジェクタブルゲルの開発2024
- Author(s)
  西口昭広
- Organizer
  医工連携フォーラム2024
- Invited
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] Design of injectable hydrogels based on liquid-liquid phase separation and their application for cell transplantation therapy2023
- Author(s)
  Akihiro Nishiguchi
- Organizer
  GPS-K2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] 術後癒着の予防に向けた液-液相分離型ホットメルト組織接着剤の設計2023
- Author(s)
  西口昭広、伊藤椎真、長坂和寛、田口哲志
- Organizer
  第72回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] Tissue-adhesive polymeric biomaterials to prevent postoperative complications2023
- Author(s)
  Akihiro NISHIGUCHI
- Organizer
  Special Seminar in Biomaterials, National Cheng Kung University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] 液-液相分離を活用した機能性インジェクタブルゲルの設計2023
- Author(s)
  西口昭広、伊藤椎真、長坂和寛、小松ひより、田口哲志
- Organizer
  第52回医用高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] 生体組織接着性バイオマテリアルの開発と医療応用2023
- Author(s)
  西口昭広
- Organizer
  2023年日本油化学会若手の会サマースクール
- Invited
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] 液-液相分離による多孔性インジェクタブルゲルの開発と幹細胞移植応用2023
- Author(s)
  西口昭広、伊藤椎真、長坂和寛、小松ひより、宇都　甲一郎、田口哲志
- Organizer
  第72回高分子学会討論会
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] Designing tissue-adhesive biomaterials toward preventing postoperative complications2023
- Author(s)
  Akihiro NISHIGUCHI
- Organizer
  2023 International Conference on Modern Challenges in Polymer Science and Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] 多孔性インジェクタブルゲルの開発と細胞移植応用2023
- Author(s)
  西口昭広、伊藤椎真、長坂和寛、小松ひより、田口哲志
- Organizer
  第61回日本人工臓器学会大会
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] Design of supramolecular tissue-adhesive hydrogels to prevent postoperative adhesion2023
- Author(s)
  Akihiro Nishiguchi, Shima Ito, Kazuhiro Nagasaka, Hiyori Komatsu, Tetsushi Taguchi
- Organizer
  ESB 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] 幹細胞移植治療に向けた多孔性インジェクタブルゲルの開発2023
- Author(s)
  西口昭広、伊藤椎真、長坂和寛、小松ひより、宇都　甲一郎、田口哲志
- Organizer
  第45回バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] ゾル-ゲル転移制御に基づく1液型ホットメルト組織接着剤の開発2022
- Author(s)
  西口昭広、市丸裕晃、伊藤椎真、長坂和寛、田口哲志
- Organizer
  第51回医用高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] ゾル-ゲル転移制御に基づくホットメルト組織接着剤の設計と癒着防止材への応用2022
- Author(s)
  西口昭広、伊藤椎真、長坂和寛、田口哲志
- Organizer
  第71回高分子討論会
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] 1液型ホットメルト組織接着剤の開発と癒着防止材への応用2022
- Author(s)
  西口昭広、伊藤椎真、長坂和寛、田口哲志
- Organizer
  第44回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] ゾル-ゲル転移制御によるホットメルト組織接着剤の開発2022
- Author(s)
  西口昭広、市丸裕晃、伊藤椎真、長坂和寛、田口哲志
- Organizer
  第60回日本接着学会年次大会
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] 術後合併症を予防する組織接着性バイオマテリアルの開発2022
- Author(s)
  西口昭広
- Organizer
  第71回高分子学会年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K25216
[Presentation] オリゴエチレンイミンによる免疫応答制御と炎症性疾患治療への応用2021
- Author(s)
  西口昭広、田口哲志
- Organizer
  第70回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-20K20207
[Presentation] 生体組織接着を実現する材料設計2021
- Author(s)
  西口昭広、田口哲志
- Organizer
  第28回次世代医工学研究会
- Data Source
  KAKENHI-PROJECT-20K20207
[Presentation] 抗炎症作用を示すポリアミンの探索と抗炎症多糖の創出2020
- Author(s)
  西口昭広，田口哲志
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-20K20207
[Presentation] 消化器がん治療に向けた噴霧可能な創傷被覆粒子の開発2019
- Author(s)
  西口昭広、田口哲志
- Organizer
  つくば医工連携フォーラム2019
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] 消化管がん術後の線維化を抑制する接着性創傷被覆粒子の創出2019
- Author(s)
  西口昭広，佐々木文郷，前田英仁，樺山　雅之，井戸章雄，田口哲志
- Organizer
  第41回日本バイオマテリアル学会年次大会
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] Tissue-adhesive colloidal wound dressing for gastrointestinal cancer, A. Nishiguchi2019
- Author(s)
  A. Nishiguchi, F. Sasaki, H. Maeda, M. Kabayama, A. Ido, T. Taguchi
- Organizer
  ABMC 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] 消化管がん術後の組織再生を促進する接着性創傷被覆粒子の開発2019
- Author(s)
  西口昭広、佐々木文郷、前田英仁、樺山雅之、井戸章雄、田口哲志
- Organizer
  第57回日本人工臓器学会大会
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] 消化管がん術後の組織再生を制御する接着性創傷被覆粒子の開発2019
- Author(s)
  西口昭広、佐々木文郷、前田英仁、樺山雅之、井戸章雄、田口哲志
- Organizer
  第68回高分子討論会
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] Development of sprayable, tissue-adhesive colloidal wound dressing for gastrointestinal cancer therapy2019
- Author(s)
  A. Nishiguchi, F. Sasaki, H. Maeda, M. Kabayama, A. Ido, T. Taguchi
- Organizer
  第68回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] 疎水化ゼラチン粒子からなる噴霧型創傷被覆材の開発2018
- Author(s)
  西口昭広、田口哲志
- Organizer
  第67回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] 消化器ガン治療後に用いる組織接着性創傷被覆粒子の開発2018
- Author(s)
  西口昭広、田口哲志
- Organizer
  第56回日本接着学会年会
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] 消化器ガン治療を指向した多機能性創傷治癒粒子の創出2018
- Author(s)
  西口昭広、田口哲志
- Organizer
  第40回バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] 消化器がん治療に向けた多機能性創傷治癒粒子の開発2018
- Author(s)
  西口昭広、田口哲志
- Organizer
  第56回人工臓器学会大会
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] Colloidal wound dressing with high tissue adhesiveness for digestive system cancer therapy2018
- Author(s)
  西口昭広、田口哲志
- Organizer
  29th Annual Meeting of the European Society for Biomaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14099
[Presentation] Development of sprayable colloidal wound dressing for digestive system cancer therapy2018
- Author(s)
  西口昭広、田口哲志
- Organizer
  2018 TERMIS World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14099

1. 山本翔太 (10785075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 田口哲志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Nishiguchi Akihiro 西口 昭広

NISHIGUCHI Akihiro 西口 昭広

Research Projects

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ゲノム編集スキャフォールドによるin vivoダイレクトリプログラミングPrincipal Investigator

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Regulation of intestinal microenvironment networks by polyamine nanoparticles and its application to the treatment of inflammatory bowel diseasePrincipal Investigator

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Development of hotmelt tissue adhesive based on controlling of sol-gel transitionPrincipal Investigator

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Development of immuno-suppressive scaffold for regenerative medicinePrincipal Investigator

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Development of wound dressing of hydrophobized colloids by controlling nano-bio interface functionsPrincipal Investigator

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[Journal Article] 組織接着剤2024

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[Journal Article] Injectable microcapillary network hydrogels engineered by liquid-liquid phase separation for stem cell transplantation2024

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[Journal Article] 生体機能化ポリマーによる免疫細胞機能制御2023

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[Journal Article] ゾル-ゲル転移制御によるホットメルト組織接着剤の創出2023

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[Journal Article] Inflammation-targeting polyamine nanomedicines for the treatment of ulcerative colitis2023

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[Journal Article] Tissue-Adhesive Decellularized Extracellular Matrix Patches Reinforced by a Supramolecular Gelator to Repair Abdominal Wall Defects2023

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[Journal Article] ゾル-ゲル転移制御に基づくホットメルト型医療用接着剤の開発と癒着防止材への応用2023

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[Journal Article] 組織接着性ハイドロゲルの設計と術後合併症予防への応用2023

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[Journal Article] Engineering thixotropic supramolecular gelatin-based hydrogel as an injectable scaffold for cell transplantation2022

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[Journal Article] 術後合併症を予防するホットメルト組織接着剤開発2022

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[Journal Article] Liquid?Liquid Phase-Separated Hydrogel with Tunable Sol?Gel Transition Behavior as a Hotmelt-Adhesive Postoperative Barrier2022

Nishiguchi Akihiro 西口昭広

NISHIGUCHI Akihiro 西口昭広