FUJIMAKI Shin 藤巻慎

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Fujimaki Shin 藤巻慎

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Researcher Number	10795678
Other IDs
Affiliation (Current)	2025: 熊本大学, 発生医学研究所, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 熊本大学, 発生医学研究所, 助教 2020: 熊本大学, 発生医学研究所, 特定事業研究員 2018 – 2019: 熊本大学, 発生医学研究所, 特別研究員(SPD・PD・RPD) 2017: 長崎大学, 医歯薬学総合研究科(歯学系), 特別研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Applied health science Except Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 59040:Nutrition science and health science-related / Basic Section 59020:Sports sciences-related
Keywords	Principal Investigator 筋萎縮 / Notch2 / Notchシグナル / 免疫制御 / ウイルス感染 / 生体防御 / 評価モデル / 単一筋線維 / 筋肥大 / 臓器連関 … More / Dll4 / Dll4-Notch2軸 / 血管内皮細胞 / 糖尿病 / 加齢 / Notch1 / 自己複製 / サテライト細胞 / 成熟筋線維 / 骨格筋幹細胞 … More Except Principal Investigator 骨格筋 / 筋萎縮 / サルコペニア / 抗がん剤有効化 / 生活習慣病モデル / スポーツ科学 / エクササイズ / 血管微小環境 / マイオカイン / DMDF / 筋再生 / 筋損傷 / 筋肥大 / 筋適応 / エピゲノム制御 / 筋可塑性 / ゲノム編集 / エピゲノム / マルチオミクス / 筋幹細胞 / エピジェネティクス / マッスルメモリー / ニッチ細胞 / 神経幹細胞 / 運動効果 / 中枢神経系 / 神経 / 成体幹細胞 / 分化 / 細胞 / 脳 / 細胞分子 / 組織幹細胞 / サテライト細胞 / 老化 / 認知機能 / 神経科学 / 幹細胞 Less

Optimization of tumor vessels normalization against anti-cancer ways with adjusted exercise therapy
- Principal Investigator
  
  南敬
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kumamoto University
骨格筋適応の分子基盤の解明に資する新規培養ツールの確立Principal Investigator
- Principal Investigator
  
  藤巻慎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kumamoto University
生体防御システムにおける骨格筋の新たな役割Principal Investigator
- Principal Investigator
  
  藤巻慎
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kumamoto University
包括的マルチオミクス解析によるマッスルメモリーの全容解明と健康長寿への応用
- Principal Investigator
  
  小野悠介
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kumamoto University
損傷筋線維由来因子による骨格筋再生制御と全身性効果の解明
- Principal Investigator
  
  小野悠介
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kumamoto University
東アジア人特有のMOTS-c遺伝子多型が2型糖尿病に関連する分子機構の解明
- Principal Investigator
  
  熊谷仁
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Juntendo University
Inter-organ regulation of skeletal muscle atrophyPrincipal Investigator
- Principal Investigator
  
  Fujimaki Shin
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kumamoto University
Effects of physical exercise on the regulation of adult stem cells existed independently in separate organs
- Principal Investigator
  
  kuwabara tomoko
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Molecular mechanism for regulating the number of muscle stem cellsPrincipal Investigator
- Principal Investigator
  
  Fujimaki Shin
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied health science
- Research Institution
  Kumamoto University
  Nagasaki University

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] The endothelial Dll4?muscular Notch2 axis regulates skeletal muscle mass2022
- Author(s)
  Fujimaki Shin、Matsumoto Tomohiro、Muramatsu Masashi、Nagahisa Hiroshi、Horii Naoki、Seko Daiki、Masuda Shinya、Wang Xuerui、Asakura Yoko、Takahashi Yukie、Miyamoto Yuta、Usuki Shingo、Yasunaga Kei-ichiro、Kamei Yasutomi、Nishinakamura Ryuichi、Minami Takashi、Fukuda Takaichi、Asakura Atsushi、Ono Yusuke
- Journal Title
  
  Nature Metabolism
  
  Volume: 4 Issue: 2 Pages: 180-189
- DOI
  10.1038/s42255-022-00533-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04058, KAKENHI-PROJECT-21K18245, KAKENHI-PROJECT-20K19641, KAKENHI-PROJECT-21K19728, KAKENHI-PROJECT-23K24796
[Journal Article] Notch signaling in the regulation of skeletal muscle stem cells2018
- Author(s)
  Fujimaki S and Ono Y
- Journal Title
  
  The Journal of Physical Fitness and Sports Medicine
  
  Volume: 7(4) Pages: 213-219
- NAID
  130007406079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K13224
[Journal Article] Effect of voluntary wheel running exercise on mitochondrial fusion and fission proteins in aged mouse skeletal muscle2018
- Author(s)
  Kitaoka Y, Fujimaki S, Machida M, Takemasa T
- Journal Title
  
  Advances in Exercise and Sports Physiology
  
  Volume: 24(3) Pages: 39-43
- NAID
  40021754747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K13224
[Journal Article] Diabetes-Induced Dysfunction of Mitochondria and Stem Cells in Skeletal Muscle and the Nervous System2017
- Author(s)
  Fujimaki S and Kuwabara T
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18(10) Issue: 10 Pages: 1-23
- DOI
  10.3390/ijms18102147
- Data Source
  KAKENHI-PROJECT-17K13224
[Journal Article] Notch1 and Notch2 Coordinately Regulate Stem Cell Function in the Quiescent and Activated States of Muscle Satellite Cells2017
- Author(s)
  Fujimaki Shin、Seko Daiki、Kitajima Yasuo、Yoshioka Kiyoshi、Tsuchiya Yoshifumi、Masuda Shinya、Ono Yusuke
- Journal Title
  
  STEM CELLS
  
  Volume: 36 Issue: 2 Pages: 278-285
- DOI
  10.1002/stem.2743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K16486, KAKENHI-PROJECT-17K13224, KAKENHI-PROJECT-16J00431, KAKENHI-PROJECT-17K13138, KAKENHI-PROJECT-16J09948
[Presentation] 組織内細胞連関による筋量調節2022
- Author(s)
  藤巻慎
- Organizer
  第7回日本血管生物医学若手研究会
- Data Source
  KAKENHI-PROJECT-20K19641
[Presentation] Endothelial－muscular axis regulates skeletal muscle mass2021
- Author(s)
  Shin Fujimaki
- Organizer
  The 16th International Symposium of the Institute Network for Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K19641
[Presentation] Roles of Notch signaling in regulating muscle plasticity and regeneration2020
- Author(s)
  藤巻慎
- Organizer
  日本薬学会第140年会シンポジウムS04
- Invited
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] Notch2 regulates muscle plasticity in adult skeletal muscle2019
- Author(s)
  Shin Fujimaki
- Organizer
  6th Protein Island Matsuyama Young Researcher’s Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] Scrib is required for efficient muscle hypertrophy following mechanical overload,” Cell Symposia: Exercise Metabolism2019
- Author(s)
  Fujimaki S, Seko D, Kitaoka Y, Kawano F, Ono Y
- Organizer
  Cell Symposia: Exercise Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] 成熟筋線維におけるNotchシグナルの役割2019
- Author(s)
  藤巻慎、松本智博、　増田慎也、西中村隆一、小野悠介
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] 細胞極性因子Scribbleによる筋可塑性制御2019
- Author(s)
  藤巻慎、瀬古大暉、小野悠介
- Organizer
  第7回骨格筋細胞若手の会
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] Role of Notch signaling in regulating muscle mass and regeneration2019
- Author(s)
  Shin Fujimaki
- Organizer
  1st Hong Kong-France Joint Symposium on Skeletal Muscle Stem Cells, Regeneration, and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] 筋線維に発現するNotch2は糖尿病性筋萎縮を制御する2019
- Author(s)
  藤巻慎、小野悠介
- Organizer
  第27回日本運動生理学会大会
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] 疾患や加齢による成体幹細胞の制御機構変化2019
- Author(s)
  桑原知子、若林玲美、藤巻慎、武政徹
- Organizer
  産総研・産技連LS-BT合同研究発表会
- Data Source
  KAKENHI-PROJECT-18K10879
[Presentation] Notchを基軸とした筋可塑性制御基盤の構築－遺伝子改変マウスを用いた解析－2019
- Author(s)
  藤巻慎
- Organizer
  第74回日本体力医学会大会シンポジウム20
- Invited
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] 細胞極性因子Scribbleによる骨格筋可塑性の制御2018
- Author(s)
  藤巻慎、北岡祐、小野悠介
- Organizer
  第26回運動生理学会大会
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] 筋分化ステージ特異的なNotchの役割2018
- Author(s)
  藤巻慎
- Organizer
  第10回分子骨格筋代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] Scrib is required for hypertrophic growth following mechanical overload in skeletal muscle2018
- Author(s)
  Fujimaki S, Seko D, Zammit P, Ono Y
- Organizer
  FASEB Science Research Conference on Skeletal Muscle Satellite Cells and Regeneration
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] 細胞極性因子Scribbleによる筋量調節2018
- Author(s)
  藤巻慎、瀬古大暉、北岡祐、河野史倫、小野悠介
- Organizer
  第6回骨格筋生物学研究会
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] 細胞極性因子Scribbleは骨格筋の量的可塑性を制御する2018
- Author(s)
  藤巻慎、瀬古大暉、北岡祐、河野史倫、小野悠介
- Organizer
  第41回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] Scrib is required for skeletal muscle hypertrophy following mechanical overload2018
- Author(s)
  Fujimaki S, Seko D, Kitaoka Y, Kawano F, Ono Y
- Organizer
  ASCM Conference on Integrative Physiology of Exercise
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] 細胞極性因子Scribbleによる筋線維組成制御2017
- Author(s)
  藤巻慎、瀬古大暉、土屋吉史、北岡祐、河野史倫、小野悠介
- Organizer
  第72回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-17K13224
[Presentation] 除負荷による骨格筋幹細胞機能の変容2017
- Author(s)
  藤巻慎、太田雄也、武政徹
- Organizer
  第25回日本運動生理学会大会
- Data Source
  KAKENHI-PROJECT-17K13224

1. 小野悠介 (60601119)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 堀居直希 (00937683)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. kuwabara tomoko (90358391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 熊谷仁 (00794819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 福典之 (40392526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 谷澤薫平 (50771812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 棗寿喜 (90761841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 古賀友紹 (30615092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 幸脇貴久 (90780784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 南敬 (00345141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 北嶋康雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 藁科知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 亀井康富

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJIMAKI Shin 藤巻 慎

Fujimaki Shin 藤巻 慎

Research Projects

Research Products

Co-Researchers

Optimization of tumor vessels normalization against anti-cancer ways with adjusted exercise therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

骨格筋適応の分子基盤の解明に資する新規培養ツールの確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生体防御システムにおける骨格筋の新たな役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

包括的マルチオミクス解析によるマッスルメモリーの全容解明と健康長寿への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

損傷筋線維由来因子による骨格筋再生制御と全身性効果の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

東アジア人特有のMOTS-c遺伝子多型が2型糖尿病に関連する分子機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Inter-organ regulation of skeletal muscle atrophyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of physical exercise on the regulation of adult stem cells existed independently in separate organs

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism for regulating the number of muscle stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The endothelial Dll4?muscular Notch2 axis regulates skeletal muscle mass2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Notch signaling in the regulation of skeletal muscle stem cells2018

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Effect of voluntary wheel running exercise on mitochondrial fusion and fission proteins in aged mouse skeletal muscle2018

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Diabetes-Induced Dysfunction of Mitochondria and Stem Cells in Skeletal Muscle and the Nervous System2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Notch1 and Notch2 Coordinately Regulate Stem Cell Function in the Quiescent and Activated States of Muscle Satellite Cells2017

FUJIMAKI Shin 藤巻慎

Fujimaki Shin 藤巻慎

[Presentation] Notchを基軸とした筋可塑性制御基盤の構築－遺伝子改変マウスを用いた解析－2019