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Sone Daichi  曽根 大地

Researcher Number 10802051
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9617-706X
Affiliation (Current) 2025: 東京慈恵会医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2021 – 2024: 東京慈恵会医科大学, 医学部, 講師
2018: 国立研究開発法人国立精神・神経医療研究センター, 脳病態統合イメージングセンター, 研究生
2017: 国立研究開発法人国立精神・神経医療研究センター, 脳病態統合イメージングセンター, 流動研究員
Review Section/Research Field
Principal Investigator
Basic Section 52030:Psychiatry-related / Neurology
Except Principal Investigator
Basic Section 52030:Psychiatry-related
Keywords
Principal Investigator
MRI / 脳画像 / てんかん / 精神症状 / 精神神経疾患 / 脳神経画像 / 放射線 / 神経科学 / 脳神経疾患 / 拡散テンソル画像 … More / 核磁気共鳴画像法(MRI) / 核医学 / グラフ理論 / 脳機能画像 / 神経突起画像 / 難治性てんかん / 側頭葉てんかん … More
Except Principal Investigator
生物学的加齢 / アパシー / アルツハイマー病 / 安静時機能的MRI / 認知行動療法 / 薬物療法 / rTMS / 共活性化現象 / 共活性化ネットワーク / 前帯状皮質膝窩部 / 治療抵抗性うつ病 Less
  • Research Projects

    (4 results)
  • Research Products

    (51 results)
  • Co-Researchers

    (6 People)
  •  生物学的加齢を用いたアルツハイマー病におけるアパシーのバイオタイピング

    • Principal Investigator
      品川 俊一郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Jikei University School of Medicine
  •  Functional dysfunction of subgenual anterior cingulate cortex through co-activation phenomenon in patients with treatment-resistant depression

    • Principal Investigator
      小高 文聰
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Jikei University School of Medicine
  •  Identifying the neural mechanisms of psychiatric and behavioral comorbidities in epilepsy using brain MRI analysisPrincipal Investigator

    • Principal Investigator
      曽根 大地
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Jikei University School of Medicine
  •  Advanced neuroimaging for understanding pathophysiology and predicting prognosis in epilepsyPrincipal Investigator

    • Principal Investigator
      Sone Daichi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Neurology
    • Research Institution
      National Center of Neurology and Psychiatry

All 2024 2023 2022 2021 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] 精神科医が行うてんかん領域での研究2024

    • Author(s)
      曽根 大地
    • Journal Title

      臨床精神医学

      Volume: 53 Pages: 201-207

    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] てんかんと認知症2024

    • Author(s)
      曽根 大地
    • Journal Title

      Medical View Point

      Volume: 45 Pages: 3-4

    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] 側頭葉てんかんのMRI診断(非正規分布拡散MRI)2023

    • Author(s)
      曽根 大地, 松田 博史
    • Journal Title

      Clinical Neuroscience

      Volume: 41 Pages: 866-868

    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] White Matter Structural Connectivity and Its Impact on Psychogenic Non-Epileptic Seizures: An Evidence-Based Review2023

    • Author(s)
      Sone Daichi
    • Journal Title

      Neuropsychiatric Disease and Treatment

      Volume: Volume 19 Pages: 1573-1579

    • DOI

      10.2147/ndt.s402378

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] 特集 All About Epilepsy 高齢者のてんかん-臨床と最近の知見2023

    • Author(s)
      曽根 大地
    • Journal Title

      BRAIN and NERVE

      Volume: 75 Issue: 4 Pages: 311-315

    • DOI

      10.11477/mf.1416202331

    • ISSN
      1344-8129, 1881-6096
    • Year and Date
      2023-04-01
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] 目でみるてんかん:先端的脳画像解析技術2023

    • Author(s)
      曽根 大地
    • Journal Title

      Epilepsy

      Volume: 17 Pages: 6-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] 精神神経医療におけるDisease-Modifying Therapy―現在地と可能性を探る―2023

    • Author(s)
      曽根 大地, 森本 悟, 中島 振一郎, 品川 俊一郎
    • Journal Title

      Psychiatria et Neurologia Japonica

      Volume: 125 Issue: 7 Pages: 569-578

    • DOI

      10.57369/pnj.23-081

    • ISSN
      0033-2658, 2436-7621
    • Year and Date
      2023-07-25
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] 「てんかんを可視化する」連載によせて2023

    • Author(s)
      曽根 大地
    • Journal Title

      Medical Science Digest

      Volume: 49 Pages: 277-279

    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] てんかんの画像診断2022

    • Author(s)
      曽根 大地
    • Journal Title

      脳神経内科

      Volume: 96 Pages: 570-577

    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] Neuroimaging-Based Brain Age Estimation: A Promising Personalized Biomarker in Neuropsychiatry2022

    • Author(s)
      Sone Daichi、Beheshti Iman
    • Journal Title

      Journal of Personalized Medicine

      Volume: 12 Issue: 11 Pages: 1850-1850

    • DOI

      10.3390/jpm12111850

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] Upper cerebellar glucose hypermetabolism in patients with temporal lobe epilepsy and interictal psychosis2022

    • Author(s)
      Sone Daichi、Sato Noriko、Shigemoto Yoko、Kimura Yukio、Matsuda Hiroshi
    • Journal Title

      Epilepsia Open

      Volume: 7 Issue: 4 Pages: 657-664

    • DOI

      10.1002/epi4.12645

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15720, KAKENHI-PROJECT-19K17157
  • [Journal Article] Neurobiological mechanisms of psychosis in epilepsy: Findings from neuroimaging studies2022

    • Author(s)
      Sone Daichi
    • Journal Title

      Frontiers in Psychiatry

      Volume: 13 Pages: 1079295-1079295

    • DOI

      10.3389/fpsyt.2022.1079295

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] てんかんにおける脳画像年齢測定と画像バイオマーカー探索2022

    • Author(s)
      曽根 大地
    • Journal Title

      精神神経学雑誌

      Volume: 124 Pages: 55-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] Making the Invisible Visible: Advanced Neuroimaging Techniques in Focal Epilepsy2021

    • Author(s)
      Sone Daichi
    • Journal Title

      Frontiers in Neuroscience

      Volume: 15 Pages: 699176-699176

    • DOI

      10.3389/fnins.2021.699176

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] 側頭葉てんかん画像診断の進歩2021

    • Author(s)
      曽根 大地, 松田 博史
    • Journal Title

      Annual Review 神経

      Volume: - Pages: 51-58

    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] Histopathological validation and clinical correlates of hippocampal subfield volumetry based on T2-weighted MRI in temporal lobe epilepsy with hippocampal sclerosis2021

    • Author(s)
      Mizutani Masashi、Sone Daichi、Sano Terunori、Kimura Yukio、Maikusa Norihide、Shigemoto Yoko、Goto Yuichi、Takao Masaki、Iwasaki Masaki、Matsuda Hiroshi、Sato Noriko、Saito Yuko
    • Journal Title

      Epilepsy Research

      Volume: 177 Pages: 106759-106759

    • DOI

      10.1016/j.eplepsyres.2021.106759

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] Clinical Application of Machine Learning Models for Brain Imaging in Epilepsy: A Review2021

    • Author(s)
      Sone Daichi、Beheshti Iman
    • Journal Title

      Frontiers in Neuroscience

      Volume: 15 Pages: 684825-684825

    • DOI

      10.3389/fnins.2021.684825

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Journal Article] Similar and differing distributions between 18F-FDG-PET and arterial spin labeling imaging in temporal lobe epilepsy2019

    • Author(s)
      Sone D, Maikusa N, Sato N, Kimura Y, Ota M, Matsuda H
    • Journal Title

      Front Neurol

      Volume: 10 Pages: 318-318

    • DOI

      10.3389/fneur.2019.00318

    • NAID

      120007133665

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Journal Article] Reduced resilience of brain gray matter networks in idiopathic generalized epilepsy: A graph-theoretical analysis2019

    • Author(s)
      Sone D, Watanabe M, Maikusa N, Sato N, Kimura Y, Enokizono M, Okazaki M, Matsuda H
    • Journal Title

      PLoS One

      Volume: 14 Issue: 2 Pages: e0212494-e0212494

    • DOI

      10.1371/journal.pone.0212494

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Journal Article] Neuroimaging-based brain age prediction in diverse forms of epilepsy: A signature of psychosis and beyond2019

    • Author(s)
      Sone D, Beheshti I, Maikusa N, Ota M, Kimura Y, Sato N, Koepp M, Matsuda H
    • Journal Title

      Mol Psychiatry

      Volume: In Press

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Journal Article] Abnormal neurite density and orientation dispersion in unilateral temporal lobe epilepsy detected by advanced diffusion imaging2018

    • Author(s)
      Sone D, Sato N, Ota M, Maikusa N, Kimura Y, Matsuda H
    • Journal Title

      Neuroimage Clin

      Volume: 20 Pages: 772-782

    • DOI

      10.1016/j.nicl.2018.09.017

    • NAID

      120007128293

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Journal Article] Brain morphological and microstructural features in cryptogenic late-onset temporal lobe epilepsy: A structural and diffusion MRI study2018

    • Author(s)
      Sone D, Sato N, Kimura Y, Watanabe Y, Okazaki M, Matsuda H
    • Journal Title

      Neuroradiology

      Volume: in press Issue: 6 Pages: 635-641

    • DOI

      10.1007/s00234-018-2019-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Journal Article] Gray Matter and White Matter Abnormalities in Temporal Lobe Epilepsy Patients with and without Hippocampal Sclerosis2018

    • Author(s)
      Beheshti I, Sone D, Farokhian F, Maikusa N, Matsuda H
    • Journal Title

      Front Neurol

      Volume: 9 Pages: 107-107

    • DOI

      10.3389/fneur.2018.00107

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Journal Article] 【こころの病気の検査・診断】 脳画像解析技術の最近の進歩(解説/特集)2018

    • Author(s)
      曽根大地, 松田博史
    • Journal Title

      アニムス

      Volume: 23 Pages: 15-18

    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Journal Article] Comparing CAT12 and VBM8 for Detecting Brain Morphological Abnormalities in Temporal Lobe Epilepsy2017

    • Author(s)
      Farokhian F, Beheshti I, Sone D, Matsuda H
    • Journal Title

      Front Neurol

      Volume: 8 Pages: 428-428

    • DOI

      10.3389/fneur.2017.00428

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Presentation] 高齢発症てんかんの診断と治療2023

    • Author(s)
      曽根 大地
    • Organizer
      第119回日本精神神経学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] White matter brain-age in diverse forms of epilepsy and interictal psychosis.2023

    • Author(s)
      Sone D, Beheshti I, Shigemoto Y, Kimura Y, Sato N, Matsuda H.
    • Organizer
      35th International Epilepsy Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] 精神医学と神経医学のボーダーランド:てんかんと精神神経医学2023

    • Author(s)
      曽根 大地
    • Organizer
      第119回日本精神神経学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] Estimated disease progression trajectory of white matter disruption in focal epilepsy: A data-driven machine-learning approach.2023

    • Author(s)
      Sone D, Sato N, Shigemoto Y, Kimura Y, Matsuda H.
    • Organizer
      35th International Epilepsy Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] てんかんと加齢・認知症:その病態的関連性2023

    • Author(s)
      曽根 大地
    • Organizer
      第119回日本精神神経学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] てんかん分野におけるDisease-Modifying Therapy: Anti-SeizureからAnti-Epileptogenesisへ2022

    • Author(s)
      曽根 大地
    • Organizer
      第118回日本精神神経学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] MRI構造画像の最近の進歩2022

    • Author(s)
      曽根 大地
    • Organizer
      第55回日本てんかん学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] Contribution of the μ-opioid receptor system to affective disorders in temporal lobe epilepsy: a bidirectional relationship?2022

    • Author(s)
      Sone D, Galovic M, Myers J, Leonhardt G, Rabiner EA, Duncan JS, Koepp MJ, Foong J.
    • Organizer
      American Epilepsy Society Annual Meeting 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] Disease Modifying Therapy とは何か?2022

    • Author(s)
      曽根 大地
    • Organizer
      第55回日本てんかん学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] Upper cerebellar glucose hypermetabolism in patients with temporal lobe epilepsy and interictal psychosis.2022

    • Author(s)
      Sone D, Sato N, Shigemoto Y, Kimura Y, Matsuda H.
    • Organizer
      14th Asian & Oceanian Epilepsy Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] Neuroimaging for Epilepsy: Principles and Progress.2022

    • Author(s)
      Sone D.
    • Organizer
      Xiangya International Pediatric Neurology Forum 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] How can we achieve healthy aging? Lessons from neuroimaging-based “brain age” studies.2022

    • Author(s)
      Sone D.
    • Organizer
      RANZCP 2022 Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] 精神科臨床における脳画像の読み方と活かし方2022

    • Author(s)
      曽根 大地
    • Organizer
      第118回日本精神神経学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] Reduced binding potential of μ-opioid receptors in temporal lobe epilepsy with psychiatric symptoms.2022

    • Author(s)
      Sone D, Galovic M, Myers J, Leonhardt G, Rabiner E, Duncan J, Koepp M, Foong J.
    • Organizer
      14th Asian & Oceanian Epilepsy Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] てんかんにおける脳画像解析:脳ネットワーク解析および先端的解析技術の臨床応用2021

    • Author(s)
      曽根 大地
    • Organizer
      第33回東京臨床脳画像解析研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] What extent of anterior temporal lobe resection is “safe”? Numerical standards for preserving postsurgical memory.2021

    • Author(s)
      Sone D, Galovic M, Thompson P, McEvoy A, Baxendale S, Koepp M
    • Organizer
      13th Asian & Oceanian Epilepsy Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] てんかんの認知機能や精神症状をターゲットとした画像バイオマーカーの探索2021

    • Author(s)
      曽根 大地
    • Organizer
      第54回日本てんかん学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] Extent of resection and optimal postsurgical memory and seizure outcome in temporal lobe epilepsy: Voxel-wise and numerical analysis.2021

    • Author(s)
      Sone D, Ahmad M, Thompson PJ, Baxendale S, Vos SB, de Tisi J, McEvoy AW, Miserocchi A, Duncan JS, Koepp MJ, Galovic M.
    • Organizer
      34th International Epilepsy Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] Histopathological validation and clinical correlates of hippocampal subfield volumetry based on T2-weighted MRI in temporal lobe epilepsy with hippocampal sclerosis.2021

    • Author(s)
      Mizutani M, Sone D, Sano T, Kumura Y, Maikusa N, Takao M, Iwasaki M, Matsuda H, Sato N, Saito Y
    • Organizer
      13th Asian & Oceanian Epilepsy Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15720
  • [Presentation] Profoundly impaired white matter integrity and brain networks in temporal lobe epilepsy with psychosis: a diffusion MRI study2019

    • Author(s)
      Sone D, Maikusa N, Sato N, Foong J, Koepp M, Matsuda H
    • Organizer
      33rd International Epilepsy Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Presentation] Signature of Psychosis: Neuroimaging-based Brain-Age gap estimation in temporal lobe epilepsy with and without psychosis2018

    • Author(s)
      Sone D, Beheshti I, Maikusa N, Matsuda H
    • Organizer
      American Epilepsy Society Annual Meeting 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Presentation] 脳画像とグラフ理論を用いた神経ネットワーク解析 - Overview and Perspectives -2018

    • Author(s)
      曽根 大地
    • Organizer
      第52回日本てんかん学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Presentation] 拡散MRIを用いた神経突起イメージングによる、側頭葉てんかんにおける焦点側神経突起密度低下の検証2018

    • Author(s)
      曽根 大地、佐藤 典子、太田 深秀、舞草 伯秀、木村 有喜男、松田 博史
    • Organizer
      第52回日本てんかん学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Presentation] 扁桃体肥大を伴う側頭葉てんかんの神経画像 - Pros and Cons -2018

    • Author(s)
      曽根 大地
    • Organizer
      第52回日本てんかん学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Presentation] Morphological and microstructural features in cryptogenic late-onset temporal lobe epilepsy: A structure and diffusion MRI study2017

    • Author(s)
      曽根 大地, 佐藤 典子, 渡辺 裕貴, 岡崎 光俊, 松田 博史
    • Organizer
      第51回日本てんかん学会
    • Data Source
      KAKENHI-PROJECT-17H07385
  • [Presentation] Nuclear Medicine in Seizures2017

    • Author(s)
      Sone D
    • Organizer
      IAEA Workshop and Final Coordination Meeting on Nuclear Medicine Techniques in Neurological Diseases II
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H07385
  • 1.  小高 文聰 (10349582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  松田 勇紀 (10726540)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  鬼頭 伸輔 (20406987)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  石井 洵平 (60814100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  品川 俊一郎 (90459628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  小林 伸行 (20385321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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