MURATA YUI 村田唯

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MURATA Yui 村田唯

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Researcher Number	10802077
Other IDs
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 学振特別研究員RPD
Affiliation (based on the past Project Information) *help	2024: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 学振特別研究員PD 2023: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 客員研究員 2023: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 訪問研究員 2020: 熊本大学, 大学院生命科学研究部(医), 特別研究員(SPD・PD・RPD) 2019: 熊本大学, 大学院生命科学研究部(医), 特別研究員(PD) 2018: 熊本大学, 大学院生命科学研究部(医), 厚労科研研究員 2017: 熊本大学, 大学院生命科学研究部, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 52030:Psychiatry-related Except Principal Investigator Psychiatric science / Basic Section 46010:Neuroscience-general-related
Keywords	Principal Investigator autism / Rett syndrome / MeCP2 / neural projection / DNA methylation / モデル動物 / 行動解析 / DNAメチル化 / エピゲノム / 胎生期 … More / 脳発達 / 母体免疫活性 / poly(I:C) / 統合失調症 / レトロトランスポゾン / LINE-1 … More Except Principal Investigator 統合失調症 / 体細胞変異 / DNAメチル化 / シナプス / 発達障害 / 脳発達 / 神経細胞 / 死後脳 / シングルセル / 全ゲノム増幅 / ゲノム / 脳神経疾患 / 精神疾患 / トランスポゾン Less

Understanding epigenetic mechanisms of neuronal growth abnormalities using a mouse model of developmental disordersPrincipal Investigator
- Principal Investigator
  
  村田唯
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Institute of Physical and Chemical Research
発達障害モデルマウスにおける皮質間シナプスの障害とそのメカニズムの解明
- Principal Investigator
  
  石田綾
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Institute of Physical and Chemical Research
Investigation of molecular mechanisms of LINE-1 regulation related to psychiatric disorders using animal modelsPrincipal Investigator
- Principal Investigator
  
  Murata Yui
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kumamoto University
Analysis of LINE-1 retrotransposition using poly(I:C) animal model
- Principal Investigator
  
  Iwamoto Kazuya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Kumamoto University
Development of techniques for analyzing somatic mutations in single neurons of psychiatric disorders
- Principal Investigator
  
  Iwamoto Kazuya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Kumamoto University

All 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] 精神科治療学「統合失調症と妊娠期ウイルス感染」2019
- Author(s)
  松原ひかり、村田唯、文東美紀、岩本和也
- Publisher
  星和書店
- Data Source
  KAKENHI-PROJECT-18K15520
[Journal Article] Global DNA hypomethylation and its correlation to the betaine level in peripheral blood of patients with schizophrenia2020
- Author(s)
  Murata Y, Ikegame T, Koike S, Saito T, Ikeda M, Sasaki T, Iwata N, Kasai K, Bundo M, Iwamoto K
- Journal Title
  
  Progress in Neuropsychopharmacology & Biological Psychiatry
  
  Volume: 99 Pages: 109855-109855
- DOI
  10.1016/j.pnpbp.2019.109855
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15520, KAKENHI-INTERNATIONAL-16K21720, KAKENHI-PLANNED-18H05430, KAKENHI-PROJECT-18H02753, KAKENHI-PROJECT-20KK0193, KAKENHI-PROJECT-18K15497, KAKENHI-PLANNED-16H06399
[Journal Article] Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology.2019
- Author(s)
  Ide M, et al. .... Kimura H, Yoshikawa T.
- Journal Title
  
  EMBO Mol Med.
  
  Volume: 11(12) Issue: 12
- DOI
  10.15252/emmm.201910695
- NAID
  120007132855
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08331, KAKENHI-PROJECT-17K08613, KAKENHI-PROJECT-19K08023, KAKENHI-PROJECT-19K08084, KAKENHI-PROJECT-18K15520, KAKENHI-PLANNED-18H05430, KAKENHI-PROJECT-17H01574, KAKENHI-PROJECT-18H02753, KAKENHI-PROJECT-19H03410, KAKENHI-PROJECT-19H03589, KAKENHI-PROJECT-20K20388, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K07578, KAKENHI-PROJECT-19K17122, KAKENHI-PROJECT-18H03579
[Journal Article] DNA methylation analyses of the candidate genes identified by a methylome-wide association study revealed common epigenetic alterations in schizophrenia and bipolar disorder.2018
- Author(s)
  Sugawara H, Murata Y, Ikegame T, Sawamura R, Shimanaga S, Takeoka Y, Saito T, Ikeda M, Yoshikawa A, Nishimura F, Kawamura Y, Kakiuchi C, Sasaki T, Iwata N, Hashimoto M, Kasai K, Kato T, Bundo M, Iwamoto K.
- Journal Title
  
  Psychiatry Clin Neurosci
  
  Volume: in press Issue: 4 Pages: 245-254
- DOI
  10.1111/pcn.12645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-16H06395, KAKENHI-PLANNED-16H06399, KAKENHI-PUBLICLY-17H05954, KAKENHI-PROJECT-15H04891, KAKENHI-PROJECT-18K15520
[Journal Article] DNA methylation profiling in a neuroblastoma cell line exposed to the antipsychotic perospirone2018
- Author(s)
  Murata Y, Bundo M, Sunaga F, Kasai K, Iwamoto K.
- Journal Title
  
  Pharmacopsychiatry
  
  Volume: in press Issue: 02 Pages: 63-69
- DOI
  10.1055/s-0044-101467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06399, KAKENHI-PROJECT-15H04891, KAKENHI-PROJECT-18K15520
[Journal Article] DNA methylation and hydroxymethylation analyses of the active LINE-1 subfamilies in mice2017
- Author(s)
  Murata Y, Bundo M, Ueda J, Kubota-Sakashita M, Kasai K, Kato T, Iwamoto K
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 13624-13624
- DOI
  10.1038/s41598-017-14165-7
- Data Source
  KAKENHI-PROJECT-15H04891
[Presentation] 多数例ゲノムサンプルを用いたSLC6A4 における新規5-HTTLPRの同定2019
- Author(s)
  池亀天平、日高洋介、菅原裕子、村田唯、渡邊理沙、清田恵美、近藤健治、池田匡志、吉川茜、西村文親、河村代志也、垣内千尋、佐々木司、石川智久、橋本衛、竹林実、岩田仲生、笠井清登、文東美紀、岩本和也
- Organizer
  第41回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] インフルエンザウイルス母体感染モデルにおける仔マウス脳試料のトランスクリプトームおよびエピゲノム解析2019
- Author(s)
  松原ひかり、村田唯、文東美紀、岩本和也
- Organizer
  第38回躁うつ病の薬理・生化学的研究懇話会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] インフルエンザウイルス母体感染仔マウスの脳内遺伝子発現状態の解析2019
- Author(s)
  松原ひかり、村田唯、文東美紀、岩本和也
- Organizer
  第41回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] poly(I:C)投与マーモセットモデルを用いたDNAメチル化異常の同定と検証2019
- Author(s)
  村田唯、上田順子、内布恵美、大西新、葛西秀俊、池亀天平、趙治磊、神出誠一郎、饗場篤、須原哲也、笠井清登、加藤忠史、文東美紀、岩本和也
- Organizer
  第41回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] インフルエンザウイルス母体感染仔マウスの脳内遺伝子発現とエピゲノム解析2019
- Author(s)
  松原ひかり、村田唯、上田順子、加藤忠史、文東美紀、岩本和也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] コホート研究における唾液試料を用いたエピゲノム解析の有用性の検討2019
- Author(s)
  藤井綾香、村田唯、金田渉、藤川慎也、池亀天平、仲地ゆたか、趙治磊、神出誠一郎、笠井清登、文東美紀、岩本和也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] 抗精神病薬リスペリドン投与によるマーモセット脳組織DNAメチル化状態への影響2019
- Author(s)
  緒方啓仁、藤井綾香、村田唯、上田順子、笠井清登、加藤忠史、文東美紀、岩本和也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] ヒト死後脳の神経細胞におけるLINE-1プロモーターのエピジェネティック修飾状態の検討2019
- Author(s)
  渡邊理紗、文東美紀、上田順子、村田唯、石井貴男、鵜飼渉、橋本恵理、笠井清登、清水史郎、加藤忠史、岩本和也
- Organizer
  第41回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] コホート研究での DNAメチル化解析における唾液試料の有用性2019
- Author(s)
  藤井綾香、金田渉、藤川慎也、村田唯、池亀天平、笠井清登、文東美紀、岩本和也
- Organizer
  第41回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] 老化モデルマウスにおけるLINE-1のコピー数の検討2019
- Author(s)
  黒木遼太、村田唯、福家聡、加藤忠史、文東美紀、岩本和也
- Organizer
  第41回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] Establishment of qPCR protocol for quantifying the copy number of active LINE-1 subfamilies in mice and its application to the aging mice2019
- Author(s)
  Kuroki R, Murata Y, Fuke S, Kujoth G, Prolla T, Kato T, Bundo M, Iwamoto K
- Organizer
  World Congress of Psychiatric Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] Investigation of abnormal molecular pathways in LINE-1 regulation in the brain using embryonic poly(I:C) model mouse2018
- Author(s)
  Yui Murata, Bundo M, Ueda J, Oh-Nishi A, Kubota-Sakashita M, Ikegame T, Suhara T, Kasai K, Kato T, Iwamoto K
- Organizer
  WFSBP 2018 Kobe
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] DNA methylation analyses of the candidate genes identified by a methylome-wide association study revealed common epigenetic alterations in schizophrenia and bipolar disorder2018
- Author(s)
  Sugawara H, Murata Y, Ikegame T, Sawamura R, Sasaki T, Iwata N, Hashimoto M, Kasai K, Kato T, Bundo M, Iwamoto K
- Organizer
  31st CINP World congress of neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] 精神疾患におけるレトロトランスポゾンとエピゲノム2018
- Author(s)
  村田唯、文東美紀、岩本和也
- Organizer
  第34回日本ストレス学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] Increased hmC levels of active LINE-1 promoter in neural precursor cells of poly(I:C) mouse model2018
- Author(s)
  Murata Y, Bundo M, Kato T, Iwamoto K
- Organizer
  Keystone symposium, Mobile Genetic Elements and Genome Plasticity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] 転移活性を有するマウスLINE-1のコピー数定量のための新規プロトコール確立2018
- Author(s)
  黒木遼太、村田唯、澤村理英、文東美紀、岩本和也
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] コホート研究でのDNAメチル化解析における唾液試料の有用性の検討、2018
- Author(s)
  藤井綾香、金田渉、藤川慎也、村田唯、池亀天平、笠井清登、文東美紀、岩本和也
- Organizer
  第37回躁うつ病の薬理・生化学研究懇話会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] マウスLINE-1コピー数定量のための新規プロトコール確立2018
- Author(s)
  黒木遼太、村田唯、文東美紀、岩本和也
- Organizer
  第37回躁うつ病の薬理・生化学研究懇話会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] Increased hmC levels of active LINE-1 promoter in neural precursor cells of poly(I:C) mouse model2018
- Author(s)
  Murata Y, Bundo M, Kato T, Iwamoto K
- Organizer
  Keystone symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04891
[Presentation] 新生児Poly（I:C）投与マーモセットモデル前頭前野組織を用いたDNAメチル化プロフィール解析2018
- Author(s)
  村田唯、上田順子、文東美紀、大西新、葛西秀俊、池亀天平、趙治磊、神出誠一郎、饗場篤、須原哲也、笠井清登、加藤忠史、岩本和也
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] リスペリドン投与マーモセット脳組織におけるDNAメチル化状態の解析2018
- Author(s)
  緒方啓仁、藤井綾香、村田唯、上田順子、笠井清登、加藤忠史、文東美紀、岩本和也
- Organizer
  第37回躁うつ病の薬理・生化学研究懇話会
- Data Source
  KAKENHI-PROJECT-18K15520
[Presentation] 神経発達期におけるpoly(I:C)母体曝露によるゲノム・エピゲノム状態への影響2016
- Author(s)
  村田唯、文東美紀、大西新、窪田-坂下美恵、池亀天平、石渡みずほ、須原哲也、笠井清登、加藤忠史、岩本和也
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-15H04891
[Presentation] 統合失調症神経発達障害モデル動物におけるDNAメチル化解析2015
- Author(s)
  村田唯、文東美紀、窪田美恵、池亀天平、上田順子、宮内妙子、井上良夢、石渡みずほ、笠井清登、加藤忠史、岩本和也
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-15H04891
[Presentation] マウスLINE-1のDNAメチル化およびハイドロキシメチル化率測定系の構築2015
- Author(s)
  村田唯、文東美紀、窪田美恵、笠井清登、加藤忠史、岩本和也
- Organizer
  第9回エピジェネティクス研究会
- Place of Presentation
  東京一ツ橋学術総合センター
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-15H04891
[Presentation] DNA methylation analysis of active LINE-1 subfamiles in an animal model of schizophrenia2015
- Author(s)
  Murata Y, Bundo M, Kubota M, Ikegame T, Miyauchi T, Inoue R, Ishiwata M, Kasai K, Kato T, Iwamoto K
- Organizer
  FASEB Science Research Conference: Mobile DNA in Mammalian Genomes
- Place of Presentation
  West Palm Beach, フロリダ, アメリカ
- Year and Date
  2015-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04891
[Presentation] Analysis of DNA methylation of LINE-1 in poly(I:C) mice2015
- Author(s)
  Murata Y, Bundo M, Kubota M, Ikegame T, Miyauchi T, Inoue R, Ishiwata M, Kasai K, Kato T, Iwamoto K
- Organizer
  第38回日本神経科学会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15H04891

1. Iwamoto Kazuya (40342753)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. BUNDO Miki (00597221)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. KATO Tadafumi (30214381)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. KASAI Kiyoto (80322056)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. SAWAMURA Rie (80509654)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KIYOTA Emi

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. UCHINUNO Emi

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. UEDA Junko

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. 石田綾 (40424171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 柴田明子 (70964245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 木村英雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MURATA YUI 村田 唯

MURATA Yui 村田 唯

Research Projects

Research Products

Co-Researchers

Understanding epigenetic mechanisms of neuronal growth abnormalities using a mouse model of developmental disordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

発達障害モデルマウスにおける皮質間シナプスの障害とそのメカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of molecular mechanisms of LINE-1 regulation related to psychiatric disorders using animal modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of LINE-1 retrotransposition using poly(I:C) animal model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of techniques for analyzing somatic mutations in single neurons of psychiatric disorders

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 精神科治療学「統合失調症と妊娠期ウイルス感染」2019

Author(s)

Publisher

Data Source

[Journal Article] Global DNA hypomethylation and its correlation to the betaine level in peripheral blood of patients with schizophrenia2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] DNA methylation analyses of the candidate genes identified by a methylome-wide association study revealed common epigenetic alterations in schizophrenia and bipolar disorder.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA methylation profiling in a neuroblastoma cell line exposed to the antipsychotic perospirone2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA methylation and hydroxymethylation analyses of the active LINE-1 subfamilies in mice2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 多数例ゲノムサンプルを用いたSLC6A4 における新規5-HTTLPRの同定2019

Author(s)

Organizer

Data Source

[Presentation] インフルエンザウイルス母体感染モデルにおける仔マウス脳試料のトランスクリプトームおよびエピゲノム解析2019

Author(s)

Organizer

Data Source

[Presentation] インフルエンザウイルス母体感染仔マウスの脳内遺伝子発現状態の解析2019

Author(s)

Organizer

Data Source

[Presentation] poly(I:C)投与マーモセットモデルを用いたDNAメチル化異常の同定と検証2019

Author(s)

Organizer

MURATA YUI 村田唯

MURATA Yui 村田唯