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Yamamoto Yuta  山本 雄大

Researcher Number 10802762
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-6129-9745
Affiliation (based on the past Project Information) *help 2020: 国立研究開発法人国立循環器病研究センター, 研究所, 流動研究員
2018 – 2019: 京都大学, 医学研究科, 研究員
2017: 京都大学, 医学部附属病院, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 53020:Cardiology-related / Cardiovascular medicine
Keywords
Principal Investigator
QT延長症候群 / iPS細胞 / 不整脈 / カルモジュリン / アンチセンス / 遺伝子治療 / イオンチャネル / カテコラミン誘発性心室頻拍 / 遺伝性心疾患 / アンチセンス核酸 / ゲノム / 循環器・高血圧
  • Research Projects

    (3 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (3 People)
  •  カルモジュリノパチーの病態解明と核酸医薬を用いた新規治療法の開発Principal Investigator

    • Principal Investigator
      山本 雄大
    • Project Period (FY)
      2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Elucidation of pathophysiological mechanisms and the development of innovative therapies for lethal arrhythmias caused by calmodulin mutationsPrincipal Investigator

    • Principal Investigator
      Yamamoto Yuta
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kyoto University
  •  カルモジュリン遺伝子関連不整脈疾患の病態解析と新規治療法の開発Principal Investigator

    • Principal Investigator
      山本 雄大
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Kyoto University

All 2020 2019 2018 2017

All Journal Article Presentation Patent

  • [Journal Article] Calmodulinopathy(カルモジュリン遺伝子関連不整脈疾患) iPS細胞技術を用いた疾患モデルの作製と遺伝子治療へのアプローチ2019

    • Author(s)
      山本 雄大,牧山 武
    • Journal Title

      心電図

      Volume: 39 Pages: 273-282

    • NAID

      130007903608

    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Journal Article] Phenotype-Based High-Throughput Classification of Long QT Syndrome Subtypes Using Human Induced Pluripotent Stem Cells2019

    • Author(s)
      Yoshinaga Daisuke、Baba Shiro、Makiyama Takeru、Shibata Hirofumi、Hirata Takuya、Akagi Kentaro、Matsuda Koichi、Kohjitani Hirohiko、Wuriyanghai Yimin、Umeda Katsutsugu、Yamamoto Yuta、Conklin Bruce R.、Horie Minoru、Takita Junko、Heike Toshio
    • Journal Title

      Stem Cell Reports

      Volume: 13 Issue: 2 Pages: 394-404

    • DOI

      10.1016/j.stemcr.2019.06.007

    • NAID

      120006786948

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08538, KAKENHI-PROJECT-19K17595, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-18K19467, KAKENHI-PROJECT-18K15847, KAKENHI-PROJECT-18H02808
  • [Journal Article] Complex aberrant splicing in the induced pluripotent stem cell?derived cardiomyocytes from a patient with long QT syndrome carrying KCNQ1-A344Aspl mutation2018

    • Author(s)
      Wuriyanghai Yimin、Makiyama Takeru、Sasaki Kenichi、Kamakura Tsukasa、Yamamoto Yuta、Hayano Mamoru、Harita Takeshi、Nishiuchi Suguru、Chen Jiarong、Kohjitani Hirohiko、Hirose Sayako、Yokoi Fumika、Gao Jingshan、Chonabayashi Kazuhisa、Watanabe Ken、Ohno Seiko、Yoshida Yoshinori、Kimura Takeshi、Horie Minoru
    • Journal Title

      Heart Rhythm

      Volume: 15 Issue: 10 Pages: 1566-1574

    • DOI

      10.1016/j.hrthm.2018.05.028

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-18K15847, KAKENHI-PROJECT-16K09499, KAKENHI-PROJECT-17H04176, KAKENHI-PROJECT-18H02808
  • [Journal Article] Clinical Manifestations and Long-Term Mortality in <i>Lamin A/C</i> Mutation Carriers From a Japanese Multicenter Registry2018

    • Author(s)
      14.Nakajima K, Aiba T, Makiyama T, Nishiuchi S, Ohno S, Kato K, Yamamoto Y, Doi T, Shizuta S, Onoue K, Yagihara N, Ishikawa T, Watanabe I, Kawakami H, Oginosawa Y, Murakoshi N, Nogami A, Aonuma K, Saito Y, Kimura T, Yasuda S, Makita N, Shimizu W, Horie M, Kusano K.
    • Journal Title

      Circ J

      Volume: 82 Issue: 11 Pages: 2707-2714

    • DOI

      10.1253/circj.CJ-18-0339

    • NAID

      40021697176

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2018-10-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-18K19550, KAKENHI-PROJECT-18K15847, KAKENHI-PROJECT-18KK0245, KAKENHI-PROJECT-16K09499, KAKENHI-PROJECT-15H04823, KAKENHI-PROJECT-18H02808, KAKENHI-PROJECT-18K15894
  • [Journal Article] Gene-Based Risk Stratification for Cardiac Disorders in LMNA Mutation Carriers.2017

    • Author(s)
      Nishiuchi S, Makiyama T, Aiba T, Nakajima K, Hirose S, Kohjitani H, Yamamoto Y, Harita T, Hayano M, Wuriyanghai Y, Chen J, Sasaki K, Yagihara N, Ishikawa T, Onoue K, Murakoshi N, Watanabe I, Ohkubo K, Watanabe H, Ohno S, Doi T, Shizuta S, Minamino T, et.al
    • Journal Title

      Circ Cardiovasc Genet.

      Volume: 6 Issue: 6

    • DOI

      10.1161/circgenetics.116.001603

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09421, KAKENHI-PROJECT-16K09499, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-15H04823, KAKENHI-PLANNED-26115008, KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-17H06806, KAKENHI-PROJECT-15K09150, KAKENHI-PROJECT-15K09689, KAKENHI-PROJECT-15K15311
  • [Journal Article] Development of a Patient-Derived Induced Pluripotent Stem Cell Model for the Investigation of <i>SCN5A</i>-D1275N-Related Cardiac Sodium Channelopathy2017

    • Author(s)
      Hayano M, Makiyama T
    • Journal Title

      Circ J

      Volume: 81 Issue: 12 Pages: 1783-1791

    • DOI

      10.1253/circj.CJ-17-0064

    • NAID

      130006219109

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09499, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-17K09860, KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17H06806
  • [Patent] アンチセンスオリゴヌクレオチド医薬のスクリーニング方法2020

    • Inventor(s)
      牧山武、山本雄大、入山友輔、近藤嘉紀、日高夕貴、石川龍太郎
    • Industrial Property Rights Holder
      牧山武、山本雄大、入山友輔、近藤嘉紀、日高夕貴、石川龍太郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Patent] CALM2のアンチセンスオリゴヌクレオチド2020

    • Inventor(s)
      入山友輔、近藤嘉紀、日高夕貴、石川龍太郎、牧山武、山本雄大
    • Industrial Property Rights Holder
      入山友輔、近藤嘉紀、日高夕貴、石川龍太郎、牧山武、山本雄大
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Preclinical Proof-of-Concept Study: Antisense-mediated Knockdown of CALM as a Therapeutic Strategy for Calmodulinopathy2020

    • Author(s)
      Yuta Yamamoto, Takeru Makiyama, Yoshiki Kondo, Yusuke Iriyama, Ryutarou Ishikawa, Yimin Wuriyanghai, Hirohiko Kohjitani, Sayako Hirose, Jingshan Gao, Asami Kashiwa, Huang Hai, Takanori Aizawa, Tomohiko Imamura, Taisuke Ishikawa, Yoshinori Yoshida, Seiko Ohno, Minoru Horie, Naomasa Makita, Takeshi Kimura
    • Organizer
      ESC Congress 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17116
  • [Presentation] Overlapping Sick Sinus Syndrome Associated with SCN5A Mutations in Patients with Brugada Syndrome2019

    • Author(s)
      Asami Kashiwa, Takeru Makiyama, Seiko Ohno, Hisaaki Aoki, Hirohiko Kohjitani Yimin Wuriyanghai, Yuta Yamamoto, Jingshan Gao, Huang Hai, Minoru Horie, Takeshi Kimura.
    • Organizer
      第83回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Phenotype-based High-throughput Classification of Long-QT Syndrome Subtypes Using Human Induced Pluripotent Stem Cells.2019

    • Author(s)
      Daisuke Yoshinaga, Shiro Baba, Takeru Makiyama, Hirofumi Shibata, Takuya Hirata, Kentaro Akagi, Koichi Matsuda, Hirohiko Kohjitani, Yimin Wuriyanghai, Katsutsugu Umeda, Yuta Yamamoto, Bruce R. Conklin, Minoru Horie, Junko Takita, Toshio Heike.
    • Organizer
      第66回日本不整脈心電学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Single Cell Electrophysiological Analysis of iPS Cell-derived Cardiomyocytes Generated from Long-QT Syndrome Patients Carrying a CALM2 Mutation Using a Membrane Potential Imaging System.2019

    • Author(s)
      Yuta Yamamoto, Takeru Makiyama(代発表), Yimin Wuriyanghai, Hirohiko Kohjitani, Sayako Hirose, Jingshan Gao, Asami Kashiwa, Huang Hai, Taisuke Ishikawa, Seiko Ohno, Kazuhisa Chonabayashi, Kenji Suda, Yoshinori Yoshida, Minoru Horie, Naomasa Makita, Takeshi Kimura,
    • Organizer
      第66回日本不整脈心電学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] KCNQ1 Channel Dysfunction in human induced pluripotent stem cell-derived cardiomyocytes carrying a CALM2-N98S mutation associated with long QT syndrome2019

    • Author(s)
      Yuta Yamamoto, Takeru Makiyama, Yimin Wuriyanghai, Hirohiko Kohjitani, Sayako Hirose, Jingshan Gao, Asami Kashiwa, Huang Hai, Takanori Aizawa, Tomohiko Imamura, Taisuke Ishikawa, Seiko Ohno, Kazuhisa Chonabayashi, Hideki Motomura, Yoshinori Yoshida, Minoru Horie, Naomasa Makita, Takeshi Kimura
    • Organizer
      American Heart Association Scientific Sessions 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Patients characteristics of idiopathic ventricular fibrillation carrying SCN5A mutations without Brugada or long QT syndrome.2019

    • Author(s)
      Takanori Aizawa, Takeru Makiyama, Hai Huang, Tomohiko Imamura, JingShan Gao, Yimin Wuriyanghai, Takeru Makiyama, Yuta Yamamoto, Hirohiko Kohjitani, Sayako Hirose, Jingshan Gao, Asami Kashiwa, Hai Huang, Wuriyanghai Yimin, Hirohiko Kohjitani, Yuta Yamamoto, Seiko Ohno, Minoru Horie
    • Organizer
      12th Asia Pacific Heart Rhythm Society Scientific Session (APHRS2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Morphological and electrophysiological characterization of homozygous lamin A/C knockout human induced-pluripotent stem cell-derived cardiomyocytes. American Heart Association Scientific Sessions 20192019

    • Author(s)
      Yimin Wuriyanghai, Takeru Makiyama, Yuta Yamamoto, Hirohiko Kohjitani, Sayako Hirose, Jingshan Gao, Asami Kashiwa, Hai Huang, Takanori Aizawa, Tomohiko Imamura, Seiko Ohno, Minoru Horie, Takeshi Kimura
    • Organizer
      American Heart Association Scientific Sessions 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Structural Insights into Catecholaminergic Polymorphic Ventricular Tachycardia-associated RyR2 Mutant Channels using a Three-dimensional in Silico Model.2019

    • Author(s)
      Jingshan Gao, Takeru Makiyama, Seiko Ohno, Yuta Yamamoto, Yimin Wuriyanghai, Hirohiko Kohjitani, Asami Kashiwa, Hai Huang, Kouichi Katou, Minoru Horie, Takeshi Kimura.
    • Organizer
      第66回日本不整脈心電学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Structural Insights into Catecholaminergic Polymorphic Ventricular Tachycardia-associated RyR2 Mutant Channels using a Three-dimensional In Silico Model.2019

    • Author(s)
      J. Gao, T. Makiyama, S. Ohno, Y. Yamamoto, Y. Wuriyanghai, H. Kohjitani, A. Kashiwa, H. Huang, K. Katou, M. Horie, T. Kimura.
    • Organizer
      European Society of Cardiology Congress 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Complex aberrant splicing in the induce pluripotent stem cell-derived cardiomyocytes from a patient with long-QT syndrome carrying KCNQ1-A344Aspl mutation.2019

    • Author(s)
      Wuriyanghai Y, Makiyama T, Sasaki K, Kamakura T, Yamamoto Y, Hayano M, Harita T, Nishiuchi S, Chen J, Kohjitani H, Hirose S, Yokoi F, Gao J, Chonabayashi K, Watanabe K, Ohno S, Yoshida Y, Kimura T, Horie M
    • Organizer
      第66回日本不整脈心電学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Algorithmic Auto-Recreation System of hiPSC-CMs Simulation and Prediction of Drug Testing.2019

    • Author(s)
      Hirohiko Kohjitani, Shigeya Kouda, Yukiko Himeno, Takeru Makiyama, Asami Kashiwa, Yimin Wuriyanghai, Yuta Yamamoto, Minoru Horie, Takeshi Kimura, Akinori Noma, Akira Amano
    • Organizer
      12th Asia Pacific Heart Rhythm Society Scientific Session (APHRS2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Modeling Overlap Syndrome Of Long QT And Brugada Syndrome Associated With CACNA1C-E1115K Which Alters Ion Selectivity With Induced Pluripotent Stem Cells2019

    • Author(s)
      Asami Kashiwa, Takeru Makiyama, Hirohiko Kohjitani, Yimin Wuriyanghai, Yuta Yamamoto, Gao Jungshan, Hai Huang, Taisuke Ishikawa, Seiko Ohno, Futoshi Toyoda, , Seiichi Sato, Minoru Horie , Naomasa Makita, Takeshi Kimura.
    • Organizer
      40th Heart Rhythm Scientific Sessions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Three-Dimensional Structural Analysis of Mutant Ryanodine Receptor Type 2 Channels Associated with Catecholaminergic Polymorphic Ventricular Tachycardia.2019

    • Author(s)
      Jingshan Gao, Takeru Makiyama, Seiko Ohno, Yuta Yamamoto, Yimin Wuriyanghai, Hirohiko Kohjitani, Asami Kashiwa, Minoru Horie, Takeshi Kimura.
    • Organizer
      第83回日本循環器学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Response of KCNQ1 to Adrenergic Stimulation was Impaired in Human Induced Pluripotent Stem Cell-derived Cardiomyocytes Carrying a CALM2-N98S Mutation Associated with Long QT Syndrome.2019

    • Author(s)
      Yuta Yamamoto, Takeru Makiyama, Yimin Wuriyanghai, Hirohiko Kohjitani, Sayako Hirose, Jingshan Gao, Asami Kashiwa, Huang Hai, Takanori Aizawa, Tomohiko Imamura, Taisuke Ishikawa, Seiko Ohno, Kazuhisa Chonabayashi, Hideki Motomura, Yoshinori Yoshida, Minoru Horie, Naomasa Makita, Takeshi Kimura
    • Organizer
      12th Asia Pacific Heart Rhythm Society Scientific Session (APHRS2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Automatic Computational Action Potential Analyzing System Enables Accurate Drug Response Interpretation and Prediction in Human Induced Pluripotent Stem Cell-derived Cardiomyocytes2019

    • Author(s)
      Hirohiko Kohjitani, Shigeya Kouda, Yukiko Himeno, Takeru Makiyama, Asami Kashiwa, Yimin Wuriyanghai, Yuta Yamamoto, Minoru Horie, Takeshi Kimura, Akinori Noma, Akira Amano.
    • Organizer
      40th Heart Rhythm Scientific Sessions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Modeling Overlapping Phenotypes of Long-QT and Brugada Syndrome with CACNA1C-E1115K that Alters Ion Selectivity of the Cardiac L-Type Calcium Channel Using Induced Pluripotent Stem Cells.2019

    • Author(s)
      Asami Kashiwa, Takeru Makiyama, Hirohiko Kohjitani, Yimin Wuriyanghai, Yuta Yamamoto, Jingshan Gao, Hai Huang, Taisuke Ishikawa, Seiko Ohno, Futoshi Toyoda, Seiichi Sato, Minoru Horie, Naomasa Makita, Takeshi Kimura
    • Organizer
      第66回日本不整脈心電学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] The Inactivation of L-type Ca2+ Cannel was Impaired in Human iPS Cell Model of Long-QT Syndrome with CALM2-D134H Mutation.2018

    • Author(s)
      山本雄大、牧山武
    • Organizer
      第 82 回 日本循環器学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Single Cell Electrophysiological Analysis of iPS Cell-derived Cardiomyocytes generated from Long-QT syndrome patients carrying a CALM2 mutation using membrane voltage imaging system.2018

    • Author(s)
      山本雄大、牧山武
    • Organizer
      The 11th Asia Pacific Heart Rhythm Society Scientific Session
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Overlapping Brugada Syndrome Associated with SCN5A Mutations in Patients with Sick Sinus Syndrome Treated with Permanent Pacemakers.2018

    • Author(s)
      柏麻美、山本雄大、牧山武
    • Organizer
      The 11th Asia Pacific Heart Rhythm Society Scientific Session
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Development of Homozygous Lamin A/C Deficient Human Induced Pluripotent Stem Cell Model for Analyzing the Pathophysiological Mechanism of Lamin A/C-related Cardiomyopathy.2018

    • Author(s)
      Wuriyanghai Yimin、山本雄大、牧山武
    • Organizer
      23rd Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Significance of cell-specific precise computer simulation using new mathematical models of human induced pluripotent stem cell derived cardiomyocyte in drug testing.2018

    • Author(s)
      糀谷泰彦、山本雄大、牧山武
    • Organizer
      ESC Congress 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Analysis of Disease-Causing Mechanism of Lamin A/C-Related Cardiomyopathy Using Homozygous Lamin A/C Knock out Human Induced Pluripotent Stem Cell Model.2018

    • Author(s)
      Wuriyanghai Yimin、山本雄大、牧山武
    • Organizer
      The 11th Asia Pacific Heart Rhythm Society Scientific Session
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Cell-specific Mathematical Modeling of hiPSC-CMs and Its Potential for Prediction of Drug Testing.2018

    • Author(s)
      糀谷泰彦、山本雄大、牧山武
    • Organizer
      23rd Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Three-dimensional Structural Analysis of Mutant Ryanodine Receptor Type 2 Channels Associated with Catecolaminergic Polymorphic Ventricular Tachycardia.2018

    • Author(s)
      高景山、山本雄大、牧山武
    • Organizer
      The 11th Asia Pacific Heart Rhythm Society Scientific Session
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Single cell analysis of CALM-related iPS cell model using membrane voltage imaging system.2018

    • Author(s)
      山本雄大、牧山武
    • Organizer
      第 2 回 日本循環器学会基礎研究フォーラム
    • Data Source
      KAKENHI-PROJECT-18K15847
  • [Presentation] Human iPSC-Derived Myocyte Model of SCN5A-D1275N-Related Cardiac Sodium Channelopathy Reveals Diminished Sodium Currents Resulting From Enhanced Protein Degradation2017

    • Author(s)
      早野護、山本雄大、牧山武
    • Organizer
      American Heart Association (AHA) Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06806
  • [Presentation] Novel Mathematical Models of All Subtypes of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes2017

    • Author(s)
      糀谷泰彦、山本雄大、牧山武
    • Organizer
      American Heart Association (AHA) Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06806
  • [Presentation] Gene-based Risk Stratification for Cardiac Disorders in LMNA Mutation Carriers2017

    • Author(s)
      西内英、山本雄大、牧山武
    • Organizer
      European Society of Cardiology (ESC) Congress 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06806
  • [Presentation] Establishment of Homozygous LMNA Knockout Human Induced Pluripotent Stem Cells For Analyzing Disease-causing Mechanism of Laminopathies2017

    • Author(s)
      Wuriyanghai Yimin、山本雄大、牧山武
    • Organizer
      American Heart Association (AHA) Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06806
  • [Presentation] Modelling long-QT syndrome type 3 associated with near-miss sudden infant death syndrome using human-induced pluripotent stem cells2017

    • Author(s)
      廣瀬紗也子、山本雄大、牧山武
    • Organizer
      American Heart Association (AHA) Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06806
  • [Presentation] CALM2-D134H Mutation Associated with Long-QT Syndrome Prevents Inactivation of L-type Ca2+ Currents in Human iPS Cells Derived Cardiomyocytes2017

    • Author(s)
      山本雄大、牧山武
    • Organizer
      APHRS2017 and JHRS2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06806
  • [Presentation] CALM2-D134H Mutation Associated with Long-QT Syndrome Delayed Inactivation of L-type Ca2+ Currents in Human iPS Cells Derived Cardiomyocytes2017

    • Author(s)
      山本雄大、牧山武
    • Organizer
      American Heart Association (AHA) Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06806
  • [Presentation] l-cis-Diltiazem ameliorates impaired calcium channel inactivation in a patient-specific stem cell model of long-QT syndrome with a calmodulin mutation2017

    • Author(s)
      横井文香、山本雄大、牧山武
    • Organizer
      Basic Cardiovascular Sciences (BCVS) Scientific Sessions 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06806
  • 1.  MAKIYAMA Takeru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  堀江 稔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  南野 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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