OTSUKA Yuta 大塚裕太

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Otsuka Yuta 大塚裕太

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Researcher Number	10822520
Other IDs
Affiliation (Current)	2025: 鹿児島大学, 医歯学域歯学系, 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 鹿児島大学, 医歯学域歯学系, 助教 2018 – 2021: 東京理科大学, 薬学部生命創薬科学科, 助教
Review Section/Research Field	Principal Investigator Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / 0801:Pharmaceutical sciences and related fields
Keywords	Principal Investigator ケモメトリックス / 共結晶 / 医薬品情報 / コラーゲン / ドラッグデリバリーシステム / メカノケミカル合成 / 破骨細胞 / アパタイト / 分子動力学 / アモルファス … More / バイオマテリアル / 深共晶 / 共アモルファス / 機械学習 / ビッグデータ解析 / 結晶多形 / 界面 Less

Research Projects
(3 results)
Research Products
(18 results)

Drug delivery system of osteoclast differentiation inhibitor with carbonate apatitePrincipal Investigator
- Principal Investigator
  
  大塚裕太
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Kagoshima University
Development and formulation of deep eutectic search method using machine learning based on drug and molecular science informationPrincipal Investigator
- Principal Investigator
  
  Otsuka Yuta
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kagoshima University
  Tokyo University of Science
Cocrystal screening for drug information for improving physical properties of drug product by cocrystallizationPrincipal Investigator
- Principal Investigator
  
  Otsuka Yuta
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0801:Pharmaceutical sciences and related fields
- Research Institution
  Tokyo University of Science

All 2024 2023 2022 2021 2019

All Journal Article Presentation

[Journal Article] Mechanochemical synthesis of cerium chlorapatite from a mixture of cerium chloride heptahydrate, dicalcium phosphate dihydrate, and calcium hydroxide for biomedical application2024
- Author(s)
  Otsuka Yuta、Kono Hiroshi、Kikuchi Masafumi
- Journal Title
  
  Bio-Medical Materials and Engineering
  
  Volume: 35 Issue: 1 Pages: 77-85
- DOI
  10.3233/bme-230073
- Data Source
  KAKENHI-PROJECT-23K16044, KAKENHI-PROJECT-22K10040
[Journal Article] Mechanochemical synthesis and characterization of strontium substituted apatite for biomedical application2023
- Author(s)
  Otsuka Yuta、Ben-Nissan Besim、Kono Hiroshi、Sasaki Tetsuo、Kikuchi Masafumi
- Journal Title
  
  Open Ceramics
  
  Volume: 16 Pages: 100459-100459
- DOI
  10.1016/j.oceram.2023.100459
- Data Source
  KAKENHI-PROJECT-23K16044, KAKENHI-PROJECT-22K10040
[Journal Article] Investigation of the crystallinity change after the addition of magnesium hydroxides into the calcium phosphate during mechanochemical synthesis: an FTIR spectroscopy, XRD analysis, chemometrics, and cell culture2023
- Author(s)
  Otsuka Yuta、Sasaki Daisuke、Kusamori Kosuke、Nishikawa Makiya、Ben-Nissan Besim
- Journal Title
  
  Journal of the Australian Ceramic Society
  
  Volume: 59 Issue: 5 Pages: 1373-1380
- DOI
  10.1007/s41779-023-00919-2
- Data Source
  KAKENHI-PROJECT-23K16044
[Journal Article] Dry and Wet Mechanochemical Synthesis of Piroxicam and Saccharin Co-Crystals and Evaluation by Powder X-Ray Diffraction, Thermal Analysis and Mid- and Near- Infrared Spectroscopy2022
- Author(s)
  Otsuka Yuta、Goto Satoru
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 111 Issue: 1 Pages: 88-94
- DOI
  10.1016/j.xphs.2021.06.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15976
[Journal Article] Dry mechanochemical synthesis of ethenzamide and saccharin 1:1 cocrystal and their evaluation using powder X-ray diffraction and FT-MIR and NIR spectroscopy2022
- Author(s)
  Otsuka Yuta、Goto Satoru
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 67 Pages: 102918-102918
- DOI
  10.1016/j.jddst.2021.102918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15976
[Journal Article] Predictive evaluation of multicomponent direct compress model tablets by integrating sphere UV-Vis spectroscopy and chemometrics2022
- Author(s)
  Otsuka Yuta、Pal Suvra
- Journal Title
  
  Bio-Medical Materials and Engineering
  
  Volume: 33 Issue: 3 Pages: 183-194
- DOI
  10.3233/bme-211269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15976
[Journal Article] Effects of polymer molecular weight on curcumin amorphous solid dispersion; at-line monitoring system based on attenuated total reflectance mid-infrared and near-infrared spectroscopy2021
- Author(s)
  Mai Nguyen Ngoc Sao、Otsuka Yuta、Goto Satoru、Kawano Yayoi、Hanawa Takehisa
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 61 Pages: 102278-102278
- DOI
  10.1016/j.jddst.2020.102278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15976
[Journal Article] Effects of Heat Treatment on Indomethacin-Cimetidine Mixture; Investigation of Drug-Drug Interaction Using Singular Value Decomposition in FTIR Spectroscopy2021
- Author(s)
  Otsuka Yuta、Kuwashima Wataru、Tanaka Yuta、Yamaki Yasuhiro、Shimada Yohsuke、Goto Satoru
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 110 Issue: 3 Pages: 1142-1147
- DOI
  10.1016/j.xphs.2020.09.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15976
[Journal Article] Effect of amino acid on calcium phosphate phase transformation: attenuated total reflectance-infrared spectroscopy and chemometrics2019
- Author(s)
  Otsuka Yuta、Ito Akira、Takeuchi Masaki、Tanaka Hideji
- Journal Title
  
  Colloid and Polymer Science
  
  Volume: 297 Issue: 1 Pages: 155-163
- DOI
  10.1007/s00396-018-4438-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21233
[Journal Article] Prediction of differential scanning calorimetry curve of theophylline directcompression model tablet using Raman spectra2019
- Author(s)
  Yuta Otsuka, Akira Ito, Suvra Pal, Hajime Mitome, Masaki Takeuchi, Hideji Tanaka
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 49 Pages: 254-259
- DOI
  10.1016/j.jddst.2018.11.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21233
[Journal Article] Bilayer Tablet Dissolution Kinetics Based on a Degassing Cyclic Flow UV-Vis Spectroscopy with Chemometrics2019
- Author(s)
  Yuta Otsuka, Akira Ito, Toru Takahashi, Saki Matsumura, Masaki Takeuchi, Hideji Tanaka
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 67 Issue: 4 Pages: 361-366
- DOI
  10.1248/cpb.c18-00867
- NAID
  130007621750
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2019-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21233
[Journal Article] Effects of temperature on terahertz spectra of caffeine/oxalic acid 2:1 cocrystal and its solid-state density functional theory2019
- Author(s)
  Otsuka Yuta、Ito Akira、Takeuchi Masaki、Sasaki Tetsuo、Tanaka Hideji
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 56 Pages: 101215-101215
- DOI
  10.1016/j.jddst.2019.101215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21233
[Presentation] Effect of strontium ions on apatite nanocrystals for biomedical application: Characterization using terahertz spectroscopy2024
- Author(s)
  Yuta Otsuka
- Organizer
  iSNIOE2: International conference on sustainable nanomaterials Integration and organization for energy and enviroment.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K16044
[Presentation] Investigation of self-setting apatite cement system using NIR spectroscopy with principal component analysis2023
- Author(s)
  Otsuka Y, Ito S, Kono H, Noguchi K, Kikuchi M.
- Organizer
  Asian Bio Ceramics 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K16044
[Presentation] 近赤外分光法を用いたエテンザミド/サッカリンの共結晶化モニタリング2022
- Author(s)
  大塚裕太、後藤了
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K15976
[Presentation] 積分球式紫外可視分光スペクトルを用いたモデル直打配合錠成分の多成分同時定量予測2019
- Author(s)
  大塚裕太, 後藤了
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-19K21233
[Presentation] 積分球式紫外可視分光スペクトルを用いたモデル直打配合錠成分の多成分同時定量予測2019
- Author(s)
  大塚裕太、後藤了
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-19K21233
[Presentation] 超モバイル近赤外分光計によるカルバマゼピン疑似結晶多形転移の研究2019
- Author(s)
  大塚　裕太、竹内　政樹、田中　秀治
- Organizer
  日本薬剤学会第34年会学会
- Data Source
  KAKENHI-PROJECT-19K21233

OTSUKA Yuta 大塚 裕太

Otsuka Yuta 大塚 裕太

Research Projects

Research Products

Drug delivery system of osteoclast differentiation inhibitor with carbonate apatitePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development and formulation of deep eutectic search method using machine learning based on drug and molecular science informationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cocrystal screening for drug information for improving physical properties of drug product by cocrystallizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Mechanochemical synthesis of cerium chlorapatite from a mixture of cerium chloride heptahydrate, dicalcium phosphate dihydrate, and calcium hydroxide for biomedical application2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanochemical synthesis and characterization of strontium substituted apatite for biomedical application2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Investigation of the crystallinity change after the addition of magnesium hydroxides into the calcium phosphate during mechanochemical synthesis: an FTIR spectroscopy, XRD analysis, chemometrics, and cell culture2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dry and Wet Mechanochemical Synthesis of Piroxicam and Saccharin Co-Crystals and Evaluation by Powder X-Ray Diffraction, Thermal Analysis and Mid- and Near- Infrared Spectroscopy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dry mechanochemical synthesis of ethenzamide and saccharin 1:1 cocrystal and their evaluation using powder X-ray diffraction and FT-MIR and NIR spectroscopy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Predictive evaluation of multicomponent direct compress model tablets by integrating sphere UV-Vis spectroscopy and chemometrics2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of polymer molecular weight on curcumin amorphous solid dispersion; at-line monitoring system based on attenuated total reflectance mid-infrared and near-infrared spectroscopy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Heat Treatment on Indomethacin-Cimetidine Mixture; Investigation of Drug-Drug Interaction Using Singular Value Decomposition in FTIR Spectroscopy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of amino acid on calcium phosphate phase transformation: attenuated total reflectance-infrared spectroscopy and chemometrics2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prediction of differential scanning calorimetry curve of theophylline directcompression model tablet using Raman spectra2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bilayer Tablet Dissolution Kinetics Based on a Degassing Cyclic Flow UV-Vis Spectroscopy with Chemometrics2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

OTSUKA Yuta 大塚裕太

Otsuka Yuta 大塚裕太