Sakamaki Junichi 坂巻純一

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Sakamaki Jun-ichi 坂巻純一

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Researcher Number	10825938
Other IDs	https://orcid.org/0000-0003-3361-6314
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2024: 順天堂大学, 大学院医学研究科, 准教授 2020 – 2022: 東京大学, 大学院医学系研究科(医学部), 特任助教
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Basic Section 43030:Functional biochemistry-related / Basic Section 44010:Cell biology-related
Keywords	Principal Investigator ユビキチン / リソソーム / 膜脂質 / プロテアソーム / ユビキチン様タンパク質 / 膵管腺がん / CRISPR-Cas9システム / オートファジー / リン脂質 / CRISPR-Cas9 / マクロピノサイトーシス

膜脂質のユビキチン化とユビキチン様タンパク質修飾によるオルガネラ機能制御Principal Investigator
- Principal Investigator
  
  坂巻純一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Juntendo University
タンパク質寿命を決定する分解装置の品質管理機構の解明Principal Investigator
- Principal Investigator
  
  坂巻純一
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Juntendo University
Identification of regulators of macropinocytosis by a genome-wide CRISPR/Cas9 screenPrincipal Investigator
- Principal Investigator
  
  Sakamaki Jun-ichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  The University of Tokyo

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Protocol to purify and detect ubiquitinated phospholipids in budding yeast and human cell lines2023
- Author(s)
  Sakamaki Jun-ichi、Mizushima Noboru
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 1 Pages: 101935-101935
- DOI
  10.1016/j.xpro.2022.101935
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04919, KAKENHI-PROJECT-20K06636
[Journal Article] The pH-sensing Rim101 pathway regulates cell size in budding yeast2023
- Author(s)
  Shimasawa Masaru、Sakamaki Jun-ichi、Maeda Tatsuya、Mizushima Noboru
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 3 Pages: 102973-102973
- DOI
  10.1016/j.jbc.2023.102973
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03251, KAKENHI-PROJECT-20K06636
[Journal Article] Cell biology of protein–lipid conjugation2023
- Author(s)
  Sakamaki Jun-ichi、Mizushima Noboru
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 48 Issue: 1 Pages: 99-112
- DOI
  10.1247/csf.23016
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06636
[Journal Article] 細胞小器官の膜リン脂質のユビキチン化2023
- Author(s)
  坂巻純一、水島昇
- Volume
  41
- Pages
  437
- DOI
  10.18958/7189-00003-0000377-00
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-22H04919, KAKENHI-PROJECT-20K06636
[Journal Article] Conjugation of the ubiquitin family proteins to phospholipids2022
- Author(s)
  Sakamaki Jun-Ichi、Mizushima Noboru
- Journal Title
  
  Autophagy
  
  Volume: 19 Issue: 4 Pages: 1361-1362
- DOI
  10.1080/15548627.2022.2123637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04919, KAKENHI-PROJECT-20K06636
[Journal Article] Ubiquitination of phosphatidylethanolamine in organellar membranes2022
- Author(s)
  Sakamaki Jun-ichi、Ode Koji L.、Kurikawa Yoshitaka、Ueda Hiroki R.、Yamamoto Hayashi、Mizushima Noboru
- Journal Title
  
  Molecular Cell
  
  Volume: 82 Issue: 19 Pages: 3677-3692.e11
- DOI
  10.1016/j.molcel.2022.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04919, KAKENHI-PROJECT-18H05270, KAKENHI-PROJECT-20K06636
[Journal Article] Silencing the G-protein coupled receptor 3-salt inducible kinase 2 pathway promotes human β cell proliferation2021
- Author(s)
  Iorio Caterina、Rourke Jillian L.、Wells Lisa、Sakamaki Jun-Ichi、Moon Emily、Hu Queenie、Kin Tatsuya、Screaton Robert A.
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1-13
- DOI
  10.1038/s42003-021-02433-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06636
[Journal Article] BRD4-mediated repression of p53 is a target for combination therapy in AML2021
- Author(s)
  Latif AL, Newcombe A, ... Sakamaki JI, ... Adams PD.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1
- DOI
  10.1038/s41467-020-20378-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06636
[Journal Article] Genome-wide CRISPR screening reveals nucleotide synthesis negatively regulates autophagy2021
- Author(s)
  Mimura Kaito、Sakamaki Jun-Ichi、Morishita Hideaki、Kawazu Masahito、Mano Hiroyuki、Mizushima Noboru
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100780-100780
- DOI
  10.1016/j.jbc.2021.100780
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06636
[Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)12021
- Author(s)
  Daniel J Klionsky、Shu Aizawa、Amal Kamal Abdel-Aziz、Sara Abdelfatah、Mahmoud Abdellatif、Asghar Abdoli、Steffen Abel、Hagai Abeliovich、Marie H Abildgaard、Yakubu Princely Abudu、Abraham Acevedo-Arozena、Iannis E Adamopoulos、Khosrow Adeli、Timon E Adolph、Annagrazia Adornetto、Elma Aflaki、Galila Agam et al.
- Journal Title
  
  Autophagy
  
  Volume: 17 Issue: 1 Pages: 1-382
- DOI
  10.1080/15548627.2020.1797280
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06375, KAKENHI-PROJECT-19K07568, KAKENHI-PROJECT-20K06501, KAKENHI-PROJECT-20K06636, KAKENHI-PROJECT-20K07896, KAKENHI-PROJECT-20K21769, KAKENHI-PLANNED-20H05772, KAKENHI-PROJECT-19H01042, KAKENHI-PROJECT-18H02439, KAKENHI-PROJECT-18H02656, KAKENHI-PROJECT-18H02807, KAKENHI-PROJECT-20J00363, KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-18K08079, KAKENHI-PROJECT-18K09427, KAKENHI-PROJECT-19K08851, KAKENHI-PROJECT-18KK0193, KAKENHI-PLANNED-19H05710, KAKENHI-PROJECT-18H02901, KAKENHI-PROJECT-20H02990, KAKENHI-PUBLICLY-20H05504, KAKENHI-PROJECT-19H03471, KAKENHI-PROJECT-19H03791, KAKENHI-PROJECT-20H03249, KAKENHI-PROJECT-19K09677, KAKENHI-PROJECT-20K07910, KAKENHI-PROJECT-20K08460, KAKENHI-PROJECT-20K08662, KAKENHI-PROJECT-21K07926, KAKENHI-PROJECT-20K21531, KAKENHI-PROJECT-19K24690, KAKENHI-PROJECT-23K21397
[Presentation] オルガネラ膜脂質ホスファチジルエタノールアミンのユビキチン化2022
- Author(s)
  坂巻純一、大出晃士、栗川義峻、上田泰己、山本林、水島昇
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K06636
[Presentation] オルガネラ膜脂質ホスファチジルエタノールアミンのユビキチン化2022
- Author(s)
  坂巻純一、大出晃士、栗川義峻、上田泰己、山本林、水島昇
- Organizer
  第33回高遠分子細胞生物学シンポジウム
- Data Source
  KAKENHI-PROJECT-20K06636
[Presentation] Ubiquitination of phosphatidylethanolamine in organellar membranes2022
- Author(s)
  Jun-ichi Sakamaki, Koji L. Ode, Yoshitaka Kurikawa, Hiroki R. Ueda, Hayashi Yamamoto, Noboru Mizushima
- Organizer
  The international symposium in Tokyo 2022 "Ubiquitin New Frontier: from Neo-Biology to Targeted Protein Degradation"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06636
[Presentation] Ubiquitination of phosphatidylethanolamine in organellar membranes2022
- Author(s)
  Jun-ichi Sakamaki, Koji L. Ode, Yoshitaka Kurikawa, Hiroki R. Ueda, Hayashi Yamamoto, Noboru Mizushima
- Organizer
  The 8th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06636
[Presentation] Ubiquitination of phosphatidylethanolamine in organellar membranes2022
- Author(s)
  Jun-ichi Sakamaki, Koji L. Ode, Yoshitaka Kurikawa, Hiroki R. Ueda, Hayashi Yamamoto, Noboru Mizushima
- Organizer
  The 23rd TMIMS International Symposium on "New Frontiers in Ubiquitin Proteasome System"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06636
[Presentation] オルガネラ膜脂質ホスファチジルエタノールアミンのユビキチン化2022
- Author(s)
  坂巻純一、大出晃士、栗川義峻、上田泰己、山本林、水島昇
- Organizer
  第74回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-20K06636
[Presentation] Ubiquitination of phosphatidylethanolamine in organellar membranes2022
- Author(s)
  Jun-ichi Sakamaki, Koji L. Ode, Yoshitaka Kurikawa, Hiroki R. Ueda, Hayashi Yamamoto, Noboru Mizushima
- Organizer
  第45回日本分子生物学会大会
- Data Source
  KAKENHI-PROJECT-20K06636
[Presentation] Ubiquitination of phosphatidylethanolamine in organellar membranes2022
- Author(s)
  坂巻純一、大出晃士、栗川義峻、上田泰己、山本林、水島昇
- Organizer
  第21回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-20K06636

1. 林剛介 (40648268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 水島昇

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
3. 前田達哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 相澤修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakamaki Junichi 坂巻 純一

Sakamaki Jun-ichi 坂巻 純一

Research Projects

Research Products

Co-Researchers

膜脂質のユビキチン化とユビキチン様タンパク質修飾によるオルガネラ機能制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

タンパク質寿命を決定する分解装置の品質管理機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of regulators of macropinocytosis by a genome-wide CRISPR/Cas9 screenPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Protocol to purify and detect ubiquitinated phospholipids in budding yeast and human cell lines2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The pH-sensing Rim101 pathway regulates cell size in budding yeast2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell biology of protein–lipid conjugation2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] 細胞小器官の膜リン脂質のユビキチン化2023

Author(s)

Volume

Pages

DOI

Language

Data Source

[Journal Article] Conjugation of the ubiquitin family proteins to phospholipids2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ubiquitination of phosphatidylethanolamine in organellar membranes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Silencing the G-protein coupled receptor 3-salt inducible kinase 2 pathway promotes human β cell proliferation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BRD4-mediated repression of p53 is a target for combination therapy in AML2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genome-wide CRISPR screening reveals nucleotide synthesis negatively regulates autophagy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)12021

Author(s)

Journal Title

DOI

Data Source

[Presentation] オルガネラ膜脂質ホスファチジルエタノールアミンのユビキチン化2022

Author(s)

Organizer

Sakamaki Junichi 坂巻純一

Sakamaki Jun-ichi 坂巻純一