Arai Yasuyuki 新井康之

Researcher Number	10826564
Other IDs	https://orcid.org/0000-0002-9662-5093
Affiliation (Current)	2025: 京都大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help	2025: 京都大学, 医学研究科, 講師 2018 – 2023: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / 0904:Internal medicine of the bio-information integration and related fields Except Principal Investigator Basic Section 59010:Rehabilitation science-related
Keywords	Principal Investigator 細胞療法運用学 / 造血器疾患 / 機械学習 / 骨髄移植 / 移植片対宿主病 / 腸管細菌叢 / 腸内細菌叢 / 造血幹前駆細胞 / キメラ抗原受容体T細胞 Except Principal Investigator 理学療法 / リハビリテーション / 運動耐容能 / キメラ抗原受容体T細胞療法

CAR-T細胞療法の最適化～臨床成績と単一細胞解析の融合による予後予測・層別化の試みPrincipal Investigator
- Principal Investigator
  
  新井康之
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Challenges in developing rehabilitation strategies for chimeric antigen receptor T-cell therapy
- Principal Investigator
  
  濱田涼太
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kyoto University
Machine-learning based approach for cellular therapy in hematological malignancyPrincipal Investigator
- Principal Investigator
  
  新井康之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
A novel prophylaxis for gut GVHD through mirobiota analysisPrincipal Investigator
- Principal Investigator
  
  Arai Yasuyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto University
Myeloid conditioning using chimeric antigen receptor T cellsPrincipal Investigator
- Principal Investigator
  
  新井康之
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0904:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyoto University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] A convolutional neural network-based model that predicts acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation2023
- Author(s)
  Jo Tomoyasu、Arai Yasuyuki、Kanda Junya、Kondo Tadakazu、Ikegame Kazuhiro、Uchida Naoyuki、Doki Noriko、Fukuda Takahiro、Ozawa Yukiyasu、Tanaka Masatsugu、Ara Takahide、Kuriyama Takuro、Katayama Yuta、Kawakita Toshiro、Kanda Yoshinobu、Onizuka Makoto、Ichinohe Tatsuo、Atsuta Yoshiko、Terakura Seitaro
- Journal Title
  
  Communications Medicine
  
  Volume: 3 Issue: 1 Pages: 67-67
- DOI
  10.1038/s43856-023-00299-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16321, KAKENHI-PROJECT-22K08501
[Journal Article] Allogeneic hematopoietic stem cell transplantation for adult Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia in second complete remission2022
- Author(s)
  Kaito Satoshi、Arai Yasuyuki、Kako Shinichi
- Journal Title
  
  Transplantation and Cellular Therapy
  
  Volume: 0 Issue: 6 Pages: 0-0
- DOI
  10.1016/j.jtct.2022.03.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17828
[Journal Article] Evaluation of indices for predicting recovery of exercise tolerance in patients surviving allogenic hematopoietic stem cell transplantation2022
- Author(s)
  Hamada Ryota、Kondo Tadakazu、Harada Kazuhiro、Murao Masanobu、Miyasaka Junsuke、Yoshida Michiko、Yonezawa Honami、Nankaku Manabu、Arai Yasuyuki、Kanda Junya、Takaori-Kondo Akifumi、Ikeguchi Ryosuke、Matsuda Shuichi
- Journal Title
  
  Supportive Care in Cancer
  
  Volume: 30 Issue: 5 Pages: 4027-4034
- DOI
  10.1007/s00520-022-06822-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17828
[Journal Article] Development of a quantitative prediction model for peripheral blood stem cell collection yield in the plerixafor era2022
- Author(s)
  Ishii Akira、Jo Tomoyasu、Arai Yasuyuki、Oshima Shinichiro、Kanda Junya、Kitawaki Toshio、Matsui Keiko、Niwa Norimi、Nakagawa Yoko、Takaori-Kondo Akifumi、Nagao Miki
- Journal Title
  
  Cytotherapy
  
  Volume: 24 Issue: 1 Pages: 49-58
- DOI
  10.1016/j.jcyt.2021.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17828, KAKENHI-PROJECT-21K16267
[Journal Article] Coexistence of HLA and KIR ligand mismatches as a risk factor for viral infection early after cord blood transplantation2022
- Author(s)
  Iemura Tomoki、Arai Yasuyuki、Takaori-Kondo Akifumi、the Kyoto Stem Cell Transplantation Group (KSCTG)
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 0 Issue: 5 Pages: 0-0
- DOI
  10.1038/s41409-022-01621-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17828
[Journal Article] Minimal residual disease (MRD) positivity at allogeneic hematopoietic cell transplantation, not the quantity of MRD, is a risk factor for relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia2021
- Author(s)
  Akahoshi Yu、Arai Yasuyuki、Nishiwaki Satoshi、Mizuta Shuichi、Marumo Atsushi、Uchida Naoyuki、Kanda Yoshinobu、Sakai Hitoshi、Takada Satoru、Fukuda Takahiro、Fujisawa Shin、Ashida Takashi、Tanaka Junji、Atsuta Yoshiko、Kako Shinichi
- Journal Title
  
  International Journal of Hematology
  
  Volume: - Issue: 6 Pages: 832-839
- DOI
  10.1007/s12185-021-03094-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17828, KAKENHI-PROJECT-20J10298
[Journal Article] Possible nosocomial transmission of virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation2021
- Author(s)
  Onda Yoshiyuki、Kanda Junya、Hanaoka Nozomu、Watanabe Mizuki、Arai Yasuyuki、Hishizawa Masakatsu、Kondo Tadakazu、Yamashita Kouhei、Nagao Miki、Fujimoto Tsuguto、Takaori-Kondo Akifumi
- Journal Title
  
  Annals of Hematology
  
  Volume: 100 Issue: 3 Pages: 753-761
- DOI
  10.1007/s00277-021-04414-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08175, KAKENHI-PROJECT-19K17828
[Journal Article] Higher exercise tolerance early after allogeneic hematopoietic stem cell transplantation is the predictive marker for higher probability of later social reintegration2021
- Author(s)
  Hamada Ryota、Arai Yasuyuki、Kondo Tadakazu、Harada Kazuhiro、Murao Masanobu、Miyasaka Junsuke、Yoshida Michiko、Yonezawa Honami、Nankaku Manabu、Ouchi Sayako、Kitakubo Wakako、Wadayama Tomoko、Kanda Junya、Takaori-Kondo Akifumi、Ikeguchi Ryosuke、Matsuda Shuichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-86744-8
- NAID
  120007026448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17828
[Journal Article] Residual disease is a strong prognostic marker in patients with acute lymphoblastic leukaemia with chemotherapy‐refractory or relapsed disease prior to allogeneic stem cell transplantation2021
- Author(s)
  Nakamura Momoko、Arai Yasuyuki、Hirabayashi Shigeki、Kondo Tadakazu、Doki Noriko、Uchida Naoyuki、Fukuda Takahiro、Ozawa Yukiyasu、Tanaka Masatsugu、Sawa Masashi、Katayama Yuta、Kanda Yoshinobu、Shiratori Souichi、Nakamae Hirohisa、Yoshioka Satoshi、Onizuka Makoto、Ichinohe Tatsuo、Atsuta Yoshiko、Kako Shinichi
- Journal Title
  
  British Journal of Haematology
  
  Volume: 194 Issue: 2 Pages: 403-413
- DOI
  10.1111/bjh.17646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17828
[Journal Article] Expanded indications for lung transplantation for pulmonary complications after hematopoietic stem cell transplantation2020
- Author(s)
  Noguchi Misa、Chen-Yoshikawa Toyofumi F.、Arai Yasuyuki、Kondo Tadakazu、Ohsumi Akihiro、Nakajima Daisuke、Hamaji Masatsugu、Takita Junko、Takaori-Kondo Akifumi、Date Hiroshi
- Journal Title
  
  The Journal of Thoracic and Cardiovascular Surgery
  
  Volume: - Issue: 4 Pages: 1549-1557.e4
- DOI
  10.1016/j.jtcvs.2020.10.065
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17828, KAKENHI-PROJECT-18H02893, KAKENHI-PROJECT-20H00528
[Journal Article] Activation of interferon regulatory factor 7 in plasmacytoid dendritic cells promotes experimental autoimmune pancreatitis2020
- Author(s)
  Minaga K, Watanabe T, Arai Y, Shiokawa M, Hara A, Yoshikawa T, Kamata K, Yamashita K, Kudo M
- Journal Title
  
  J Gastroenterol
  
  Volume: - Issue: 5 Pages: 565-576
- DOI
  10.1007/s00535-020-01662-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08455, KAKENHI-PROJECT-19K17506, KAKENHI-PROJECT-19K17828
[Journal Article] Risk factors and appropriate therapeutic strategies for thrombotic microangiopathy after allogeneic HSCT2020
- Author(s)
  Matsui Hiroyuki、Arai Yasuyuki、et al
- Journal Title
  
  Blood Advances
  
  Volume: 4 Issue: 13 Pages: 3169-3179
- DOI
  10.1182/bloodadvances.2020002007
- NAID
  120006875283
- Data Source
  KAKENHI-PROJECT-19K17828
[Journal Article] Indication and benefit of upfront hematopoietic stem cell transplantation for T-cell lymphoblastic lymphoma in the era of ALL-type induction therapies2020
- Author(s)
  Morita-Fujita Mari、Kyoto Stem Cell Transplantation Group (KSCTG)、Arai Yasuyuki、Yoshioka Satoshi、Ishikawa Takayuki、Kanda Junya、Kondo Tadakazu、Akasaka Takashi、Ueda Yasunori、Imada Kazunori、Moriguchi Toshinori、Yago Kazuhiro、Kitano Toshiyuki、Yonezawa Akihito、Nohgawa Masaharu、Takaori-Kondo Akifumi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41598-020-78334-x
- NAID
  120006956388
- Data Source
  KAKENHI-PROJECT-19K17828
[Journal Article] Impact of HLA class I allele-level mismatch on viral infection within 100?days after cord blood transplantation2020
- Author(s)
  Iemura Tomoki、Arai Yasuyuki、Kanda Junya、Kitawaki Toshio、Hishizawa Masakatsu、Kondo Tadakazu、Yamashita Kouhei、Takaori-Kondo Akifumi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41598-020-78259-5
- Data Source
  KAKENHI-PROJECT-19K17828
[Journal Article] Impact of Donor Source on Allogeneic Hematopoietic Stem Cell Transplantation for Mature T Cell and Natural Killer Cell Neoplasms in the Kyoto Stem Cell Transplantation Group2020
- Author(s)
  Watanabe Mizuki、Kanda Junya、Arai Yasuyuki、Takaori-Kondo Akifumi、et al
- Journal Title
  
  Biology of Blood and Marrow Transplantation
  
  Volume: 26 Issue: 12 Pages: 2346-2358
- DOI
  10.1016/j.bbmt.2020.07.032
- Data Source
  KAKENHI-PROJECT-19K17828
[Journal Article] Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia conducted in Japan during the past quarter century2020
- Author(s)
  Yanada Masamitsu、Takami Akiyoshi、Yamasaki Satoshi、Arai Yasuyuki、Konuma Takaaki、Uchida Naoyuki、Najima Yuho、Fukuda Takahiro、Tanaka Masatsugu、Ozawa Yukiyasu、Ikegame Kazuhiro、Takanashi Minoko、Ichinohe Tatsuo、Okamoto Shinichiro、Atsuta Yoshiko、Yano Shingo
- Journal Title
  
  Annals of Hematology
  
  Volume: 99 Issue: 6 Pages: 1351-1360
- DOI
  10.1007/s00277-020-04051-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-20K08748, KAKENHI-PROJECT-19K17828
[Journal Article] Drug monitoring for mycophenolic acid in graft‐ vs ‐host disease prophylaxis in cord blood transplantation2020
- Author(s)
  Muranushi Hiroyuki、Kanda Junya、Arai Yasuyuki、Shindo Takero、Hishizawa Masakatsu、Yamamoto Takashi、Kondo Tadakazu、Yamashita Kohei、Matsubara Kazuo、Takaori‐Kondo Akifumi
- Journal Title
  
  British Journal of Clinical Pharmacology
  
  Volume: 86 Issue: 12 Pages: 2464-2472
- DOI
  10.1111/bcp.14354
- NAID
  120006938957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17828, KAKENHI-PROJECT-19K08812
[Journal Article] Myeloid Conditioning with c-kit-Targeted CAR-T Cells Enables Donor Stem Cell Engraftment2018
- Author(s)
  Arai Yasuyuki、Choi Uimook、Corsino Cristina I.、Koontz Sherry M.、Tajima Masaki、Sweeney Colin L.、Black Mary A.、Feldman Steven A.、Dinauer Mary C.、Malech Harry L.
- Journal Title
  
  Molecular Therapy
  
  Volume: 26 Issue: 5 Pages: 1181-1197
- DOI
  10.1016/j.ymthe.2018.03.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H06231
[Presentation] CAR-T細胞療法後の運動耐容能の低下に影響を及ぼすリスク因子の検討2023
- Author(s)
  濱田涼太，新井康之，北脇年雄，村尾昌信，松下路子，宮坂淳介，太田垣あゆみ，浅野伝美，福田裕子，錦織桃子，諫田淳也，水本智咲，池口良輔，松田秀一，髙折晃史
- Organizer
  第46回日本造血・免疫細胞療法学会
- Data Source
  KAKENHI-PROJECT-23K10558
[Presentation] Dysbiosis in gut microbiota after allogeneic hematopoietic stem cell transplantation can be determined by the combination of conditioning regimen and antibiotic usage2019
- Author(s)
  Yasuyuki Arai, Takamitsu Tsukahara, Miki Nagao, Tadakazu Kondo, Akifumi Takaori-Kondo
- Organizer
  24th European Hematology Association (Amsterdam, Netherland)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17828
[Presentation] 同種移植後の腸内細菌叢の変化に対する前処置および抗生剤使用の影響2019
- Author(s)
  新井康之, 塚原隆充, 松元加奈, 長尾美紀, 近藤忠一, 髙折晃史
- Organizer
  第81回日本血液学会総会（東京）
- Data Source
  KAKENHI-PROJECT-19K17828
[Presentation] c-kitを標的としたキメラ抗原受容体T細胞（CAR-T）による新規骨髄移植前処置の開発2018
- Author(s)
  新井康之, Harry Malech, 髙折晃史
- Organizer
  第80回日本血液学会学術集会（大阪）
- Data Source
  KAKENHI-PROJECT-18H06231
[Presentation] Myeloid conditioning with c-kit-targeted CAR-T cells enables donor stem cell engraftment without high-dose chemotherapy or radiation2018
- Author(s)
  Yasuyuki Arai, Harry Malech, Akifumi Takaori-Kondo
- Organizer
  The 23rd Annual Congress of 2018 Asia-Pacific Blood and Marrow Transplantation Group (Taipei, Taiwan)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H06231

1. 濱田涼太 (00894750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 城友泰 (20894348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 松井宏行 (31004567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 村川泰裕 (50765469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KUDO Masatoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. WATANABE Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 藤本嗣人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 高見昭良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Arai Yasuyuki 新井 康之

Research Projects

Research Products

Co-Researchers

CAR-T細胞療法の最適化～臨床成績と単一細胞解析の融合による予後予測・層別化の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Challenges in developing rehabilitation strategies for chimeric antigen receptor T-cell therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Machine-learning based approach for cellular therapy in hematological malignancyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel prophylaxis for gut GVHD through mirobiota analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Myeloid conditioning using chimeric antigen receptor T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] A convolutional neural network-based model that predicts acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Allogeneic hematopoietic stem cell transplantation for adult Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia in second complete remission2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of indices for predicting recovery of exercise tolerance in patients surviving allogenic hematopoietic stem cell transplantation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a quantitative prediction model for peripheral blood stem cell collection yield in the plerixafor era2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Coexistence of HLA and KIR ligand mismatches as a risk factor for viral infection early after cord blood transplantation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Minimal residual disease (MRD) positivity at allogeneic hematopoietic cell transplantation, not the quantity of MRD, is a risk factor for relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Possible nosocomial transmission of virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Higher exercise tolerance early after allogeneic hematopoietic stem cell transplantation is the predictive marker for higher probability of later social reintegration2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Residual disease is a strong prognostic marker in patients with acute lymphoblastic leukaemia with chemotherapy‐refractory or relapsed disease prior to allogeneic stem cell transplantation2021

Author(s)

Journal Title

DOI

Data Source

Arai Yasuyuki 新井康之