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kimishima aoi  君嶋 葵

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Kimishima Aoi  君嶋 葵

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Researcher Number 10832404
Other IDs
Affiliation (Current) 2025: 北里大学, 感染制御科学府, 講師
Affiliation (based on the past Project Information) *help 2025: 北里大学, 感染制御科学府, 講師
2020 – 2024: 北里大学, 感染制御科学府, 助教
2023: 北里大学, 感染制御科学府, 講師
Review Section/Research Field
Principal Investigator
Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Except Principal Investigator
Basic Section 47050:Environmental and natural pharmaceutical resources-related
Keywords
Principal Investigator
天然物 / 抗感染症薬 / 三型分泌機構 / グラム陰性細菌 / 化合物ライブラリー構築 / 構造活性相関研究 / エバーメクチン / 創薬化学 / マクロライド / ケミカルライブラリー / 全合成 … More
Except Principal Investigator
… More 天然化合物 / 増強活性物質 / マクロライド / 多剤耐性菌 / 緑膿菌 / 微生物由来 / MRSA / 生物活性物質 / 薬剤耐性因子 Less
  • Research Projects

    (5 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (4 People)
  •  16員環マクロライドを基盤とした広域抗グラム陰性細菌剤の創製研究Principal Investigator

    • Principal Investigator
      君嶋 葵
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Kitasato University
  •  緑膿菌感染症治療に有効な5-o-mycaminosyltylonolide (OMT) 増強活性物質の創製

    • Principal Investigator
      本庄 雅子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Kitasato University
  •  新規作用機序を有する抗感染症薬創製に向けたグラム陰性細菌三型分泌機構阻害剤の開発Principal Investigator

    • Principal Investigator
      君嶋 葵
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Kitasato University
  •  Discovery of microorganism-derived anti-MRSA therapeutic seed compounds that inhibit drug resistance factors

    • Principal Investigator
      Asami Yukihiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Kitasato University
  •  Establishment of a Convergent Synthesis of Omura Natural Products Evermectins with Novel Structures and Biological ActivitiesPrincipal Investigator

    • Principal Investigator
      Kimishima Aoi
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Kitasato University

All 2024 2023

All Journal Article Presentation

  • [Journal Article] The potentiation activity of β-lactam by phomoidrides and oxasetin against methicillin-resistant Staphylococcus aureus2024

    • Author(s)
      Honsho Masako、Kimishima Aoi、Ikeda Akari、Iwatsuki Masato、Nonaka Kenichi、Matsui Hidehito、Hanaki Hideaki、Asami Yukihiro、Sunazuka Toshiaki
    • Journal Title

      The Journal of Antibiotics

      Volume: 77 Issue: 3 Pages: 185-188

    • DOI

      10.1038/s41429-023-00691-2

    • Data Source
      KAKENHI-PROJECT-21K06616
  • [Journal Article] A new tetronomycin analog, broad‐spectrum and potent antibiotic against drug‐resistant Gram‐positive bacteria2024

    • Author(s)
      Kimishima Aoi、Tsuruoka Iori、Tsutsumi Hayama、Honsho Masako、Honma Sota、Matsui Hidehito、Sugamata Miho、Wasuwanich Paul、Inahashi Yuki、Hanaki Hideaki、Asami Yukihiro
    • Journal Title

      Chemistry & Biodiversity

      Volume: 21 Issue: 2

    • DOI

      10.1002/cbdv.202301834

    • Data Source
      KAKENHI-PROJECT-22K15305, KAKENHI-PROJECT-21K06616
  • [Journal Article] Rediscovery of tetronomycin as a broad-spectrum and potent antibiotic against drug-resistant Gram-positive bacteria2023

    • Author(s)
      Aoi Kimishima, Iori Tsuruoka, Hiroki Kanto, Hayama Tsutsumi, Naoaki Arima, Kazunari Sakai, Miho Sugamata, Hidehito Matsui, Yoshihiro Watanabe, Masato Iwatsuki, Masako Honsho, Kamrun Naher, Yuki Inahashi, Hideaki Hanaki, Yukihiro Asami
    • Journal Title

      ACS Omega

      Volume: 8 Issue: 12 Pages: 11556-11563

    • DOI

      10.1021/acsomega.3c00651

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06616, KAKENHI-PROJECT-22K15305
  • [Presentation] 薬剤耐性グラム陽性細菌に対する広域かつ強力な抗菌活性を示すテトロノマイシンの再発見2023

    • Author(s)
      鶴岡伊織, 君嶋葵, 菅藤裕貴, 堤隼馬, 有馬直明, 酒井 一成, 菅又美穂, 松井秀仁, 渡邊善洋, 岩月正人, 本庄雅子, Naher Kamrun, 稲橋佑起, 花木秀明, 浅見行弘
    • Organizer
      日本農芸化学会2023年度大会 2023年3月15日
    • Data Source
      KAKENHI-PROJECT-21K06616
  • [Presentation] 抗薬剤耐性グラム陽性細菌物質テトロノマイシンの再発見とその作用機序解析2023

    • Author(s)
      鶴岡伊織, 君嶋葵, 菅藤裕貴, 堤隼馬, 有馬直明, 酒井一成, 菅又美穂, 松井秀仁, 渡邊善洋, 岩月正人, 本庄雅子, Naher Kamrun, 本間颯太, 稲橋佑起, 花木秀明, 浅見行弘
    • Organizer
      第65回 天然有機化合物討論会 2023年9月4日
    • Data Source
      KAKENHI-PROJECT-21K06616
  • 1.  Asami Yukihiro (70391844)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 2.  本庄 雅子 (50870581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  松井 秀仁 (80503797)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  堤 隼馬
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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