IMAIZUMI Kent 今泉研人

Researcher Number	10835846
Other IDs	https://orcid.org/0000-0002-3565-5248
Affiliation (based on the past Project Information) *help	2019 – 2022: 慶應義塾大学, 医学部(信濃町), 特任助教
Review Section/Research Field	Principal Investigator Complex systems / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator 領域特異性 / オーガナイザー / オルガノイド / 再生医療 / 脊髄損傷 / 神経幹細胞 / iPS細胞

Organoid-based model of symmetry breaking in organogenesisPrincipal Investigator
- Principal Investigator
  
  今泉研人
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Keio University
Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cellsPrincipal Investigator
- Principal Investigator
  
  IMAIZUMI Kent
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Keio University

All 2022 2021 2020 2019 Other

All Journal Article Presentation Other

[Journal Article] Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms2022
- Author(s)
  Ideno Hirosato、Imaizumi Kent、Shimada Hiroko、Sanosaka Tsukasa、Nemoto Akisa、Kohyama Jun、Okano Hideyuki
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 10 Pages: 105140-105140
- DOI
  10.1016/j.isci.2022.105140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03623, KAKENHI-PUBLICLY-21H00438
[Journal Article] Gene therapy using genome-edited iPS cells for targeting malignant glioma2022
- Author(s)
  Tamura Ryota、Miyoshi Hiroyuki、Imaizumi Kent、Yo Masahiro、Kase Yoshitaka、Sato Tsukika、Sato Mizuto、Morimoto Yukina、Sampetrean Oltea、Kohyama Jun、Shinozaki Munehisa、Miyawaki Atsushi、Yoshida Kazunari、Saya Hideyuki、Okano Hideyuki、Toda Masahiro
- Journal Title
  
  Bioengineering & Translational Medicine
  
  Volume: e10406 Issue: 5
- DOI
  10.1002/btm2.10406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03046, KAKENHI-PUBLICLY-21H00438
[Journal Article] Pathogenic mutation of TDP-43 impairs RNA processing in a cell type-specific manner: implications for the pathogenesis of ALS/FTLD2022
- Author(s)
  Kent Imaizumi, Hirosato Ideno, Tsukika Sato, Satoru Morimoto, and Hideyuki Okano
- Journal Title
  
  eNeuro
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00438
[Journal Article] A non-invasive system to monitor in vivo neural graft activity after spinal cord injury2022
- Author(s)
  Ago K、Nagoshi N、Imaizumi K、Kitagawa T、Kawai M、Kajikawa K、Shibata R、Kamata Y、Kojima K、Shinozaki M、Kondo T、Iwano S、Miyawaki A、Ohtsuka M、Bito H、Kobayashi K、Shibata S、Shindo T、Kohyama J、Matsumoto M、Nakamura M、Okano H
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 803-803
- DOI
  10.1038/s42003-022-03736-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03623, KAKENHI-PROJECT-20H03178, KAKENHI-PUBLICLY-21H00438, KAKENHI-PLANNED-17H06312, KAKENHI-PROJECT-23K24464
[Journal Article] Generation of region-specific and high-purity neurons from human feeder-free iPSCs2021
- Author(s)
  Sato Tsukika、Imaizumi Kent、Watanabe Hirotaka、Ishikawa Mitsuru、Okano Hideyuki
- Journal Title
  
  Neuroscience Letters
  
  Volume: 746 Pages: 135676-135676
- DOI
  10.1016/j.neulet.2021.135676
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20J21586, KAKENHI-PROJECT-19K16927
[Journal Article] Non-viral Induction of Transgene-free iPSCs from Somatic Fibroblasts of Multiple Mammalian Species.2021
- Author(s)
  Yoshimatsu S, Nakajima M, Iguchi A, Sanosaka T, Sato T, Nakamura M, Nakajima R, Arai E, Ishikawa M, Imaizumi K, Watanabe H, Okahara J, Noce T, Takeda Y, Sasaki E, Behr R, Edamura K, Shiozawa S, Okano H.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 16 Issue: 4 Pages: 754-770
- DOI
  10.1016/j.stemcr.2021.03.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07444, KAKENHI-PROJECT-19K16927, KAKENHI-PROJECT-20K22660, KAKENHI-PROJECT-20H03156, KAKENHI-PROJECT-21J00381, KAKENHI-PROJECT-21K15112
[Journal Article] Flexible and Accurate Substrate Processing with Distinct Presenilin/γ-Secretases in Human Cortical Neurons2021
- Author(s)
  Watanabe Hirotaka、Imaizumi Kent、Cai Tetsuo、Zhou Zhi、Tomita Taisuke、Okano Hideyuki
- Journal Title
  
  eneuro
  
  Volume: 8 Issue: 2 Pages: 0-1
- DOI
  10.1523/eneuro.0500-20.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-19K16927
[Journal Article] Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells2020
- Author(s)
  Kajikawa Keita、Imaizumi Kent、Shinozaki Munehisa、Shibata Shinsuke、Shindo Tomoko、Kitagawa Takahiro、Shibata Reo、Kamata Yasuhiro、Kojima Kota、Nagoshi Narihito、Matsumoto Morio、Nakamura Masaya、Okano Hideyuki
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 1-12
- DOI
  10.1186/s13041-020-00662-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14840, KAKENHI-PROJECT-19K16927
[Journal Article] Human Astrocytes Model Derived from Induced Pluripotent Stem Cells2020
- Author(s)
  Leventoux Nicolas、Morimoto Satoru、Imaizumi Kent、Sato Yuta、Takahashi Shinichi、Mashima Kyoko、Ishikawa Mitsuru、Sonn Iki、Kondo Takahiro、Watanabe Hirotaka、Okano Hideyuki
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 12 Pages: 2680-2680
- DOI
  10.3390/cells9122680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08002, KAKENHI-PROJECT-20K16502, KAKENHI-PROJECT-19K16927
[Journal Article] Modeling neurodevelopment in a dish with pluripotent stem cells2020
- Author(s)
  Imaizumi Kent、Okano Hideyuki
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 63 Issue: 1 Pages: 18-25
- DOI
  10.1111/dgd.12699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16927
[Journal Article] Single‐cell study of neural stem cells derived from human iPSCs reveals distinct progenitor populations with neurogenic and gliogenic potential2019
- Author(s)
  Lam Matti、Sanosaka Tsukasa、Lundin Anders、Imaizumi Kent、Etal Damla、Karlsson Fredrik H.、Clausen Maryam、Cairns Jonathan、Hicks Ryan、Kohyama Jun、Kele Malin、Okano Hideyuki、Falk Anna
- Journal Title
  
  Genes to Cells
  
  Volume: 24 Issue: 12 Pages: 836-847
- DOI
  10.1111/gtc.12731
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16927
[Journal Article] A combinational treatment of carotenoids decreases Aβ secretion in human neurons via β-secretase inhibition2019
- Author(s)
  Sho Misato、Ichiyanagi Naoki、Imaizumi Kent、Ishikawa Mitsuru、Morimoto Satoru、Watanabe Hirotaka、Okano Hideyuki
- Journal Title
  
  Neuroscience Research
  
  Volume: － Pages: 47-55
- DOI
  10.1016/j.neures.2019.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16927, KAKENHI-PROJECT-17K08668
[Presentation] Self-patterning of brain organoids by adhesion-based cell assembly2022
- Author(s)
  Kent Imaizumi
- Organizer
  9th Stanford-Keio Webinar
- Data Source
  KAKENHI-PUBLICLY-21H00438
[Presentation] Size-scaled patterning of neural organoids2021
- Author(s)
  Kent Imaizumi
- Organizer
  ISSCR Tokyo 2021 International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00438
[Presentation] Self-patterning of brain organoids2021
- Author(s)
  Kent Imaizumi
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00438
[Presentation] Neural spheroid model for the study of neural patterning2021
- Author(s)
  Imaizumi Kent, Hideyuki Okano
- Organizer
  The 2nd Stanford-Keio Webinar
- Data Source
  KAKENHI-PROJECT-19K16927
[Presentation] 脊髄損傷治療におけるiPS細胞由来神経細胞の領域特異性の重要性2020
- Author(s)
  梶川慶太、名越慈人、今泉研人、篠崎宗久、神山淳、松本守雄、岡野栄之、中村雅也
- Organizer
  第19回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K16927
[Presentation] The cerebral cortex patterning in hPSC-derived organoids2019
- Author(s)
  Imaizumi Kent, Hideyuki Okano
- Organizer
  20th TMIMS International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16927
[Presentation] Rostrocaudal areal patterning of human ESC/iPSC-derived cortical neurons by FGF8 signaling2019
- Author(s)
  Imaizumi Kent, Hideyuki Okano
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K16927
[Presentation] Recapitulation of the areal patterning in the cerebral cortex by human ESC/iPSC-derived cortical neurons2019
- Author(s)
  Imaizumi Kent, Hideyuki Okano
- Organizer
  49th Annual Meeting of the Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16927
[]

1. ARAI Eri

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. TAKAHASHI Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 芝田晋介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 神山淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 戸田正博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 富田泰輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 森本悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 岡野栄之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IMAIZUMI Kent 今泉 研人

Research Projects

Research Products

Co-Researchers

Organoid-based model of symmetry breaking in organogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene therapy using genome-edited iPS cells for targeting malignant glioma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathogenic mutation of TDP-43 impairs RNA processing in a cell type-specific manner: implications for the pathogenesis of ALS/FTLD2022

Author(s)

Journal Title

Data Source

[Journal Article] A non-invasive system to monitor in vivo neural graft activity after spinal cord injury2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of region-specific and high-purity neurons from human feeder-free iPSCs2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Non-viral Induction of Transgene-free iPSCs from Somatic Fibroblasts of Multiple Mammalian Species.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Flexible and Accurate Substrate Processing with Distinct Presenilin/γ-Secretases in Human Cortical Neurons2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Astrocytes Model Derived from Induced Pluripotent Stem Cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modeling neurodevelopment in a dish with pluripotent stem cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single‐cell study of neural stem cells derived from human iPSCs reveals distinct progenitor populations with neurogenic and gliogenic potential2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A combinational treatment of carotenoids decreases Aβ secretion in human neurons via β-secretase inhibition2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Self-patterning of brain organoids by adhesion-based cell assembly2022

Author(s)

Organizer

Data Source

[Presentation] Size-scaled patterning of neural organoids2021

IMAIZUMI Kent 今泉研人