Nakamichi Shinji 中道真仁

Researcher Number	10837446
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 日本医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related Except Principal Investigator Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator FOXO3a / Foxo3a / 上皮成長因子受容体 / 非小細胞肺癌 / アポトーシス / 薬剤獲得耐性 / 分子標的薬 / 薬物療法 / 薬剤耐性 / 肺癌 … More Except Principal Investigator … More EGFR変異 / 耐性克服療法 / 薬剤耐性 / 代謝リプログラミング Less

分子標的薬耐性肺がんにおける薬剤耐性獲得機構の解明と代謝制御を利用した治療法開発
- Principal Investigator
  
  中嶋亘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School
Novel strategy targeting apoptosis regulators for non-small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  Nakamichi Shinji
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Afatinib plus PEM and CBDCA overcome osimertinib-resistance in EGFR-mutated NSCLC with high thrombospondin-1 expression2024
- Author(s)
  Onda Naomi, Nakamichi Shinji, Hirao Mariko, Matsuda Kuniko, Matsumoto Masaru, Miyanaga Akihiko, Noro Rintaro, Gemma Akihiko, Seike Masahiro
- Journal Title
  
  Cancer Science
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17200
[Journal Article] Phosphoproteomic Analysis Identified Mutual Phosphorylation of FAK and Src as a Mechanism of Osimertinib Resistance in EGFR-Mutant Lung Cancer2024
- Author(s)
  Tozuka Takehiro、Noro Rintaro、Yoshida Keisuke、Takahashi Satoshi、Hirao Mariko、Matsuda Kuniko、Kato Yasuhiro、Nakamichi Shinji、Takeuchi Susumu、Matsumoto Masaru、Miyanaga Akihiko、Kunugi Shinobu、Honda Kazufumi、Adachi Jun、Seike Masahiro
- Journal Title
  
  JTO Clinical and Research Reports
  
  Volume: 5 Issue: 4 Pages: 100668-100668
- DOI
  10.1016/j.jtocrr.2024.100668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17200, KAKENHI-PROJECT-17KK0177
[Journal Article] nduction of resistance to neurotrophic tropomyosin-receptor kinase inhibitors by HMGCS2 via a mevalonate pathway2024
- Author(s)
  Kato Yasuhiro, Masaru Matsumoto, Takano Natsuki, Hirao Mariko, Matsuda Kuniko, Tozuka Takehiro, Onda Naomi, Nakamichi Shinji, Takeuchi Susumu, Miyanaga Akihiko, Noro Rintaro, Gemma Akihiko, Seike Masahiro
- Journal Title
  
  Cancer Medicine
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17200
[Journal Article] Serum-derived exosomal miR-125a-3p predicts the response to anti-programmed cell death-1/programmed cell death-ligand 1 monotherapy in patients with non-small cell lung cancer2023
- Author(s)
  Hisakane Kakeru、Seike Masahiro、Sugano Teppei、Matsuda Kuniko、Kashiwada Takeru、Nakamichi Shinji、Matsumoto Masaru、Miyanaga Akihiko、Noro Rintaro、Kubota Kaoru、Gemma Akihiko
- Journal Title
  
  Gene
  
  Volume: 857 Pages: 147177-147177
- DOI
  10.1016/j.gene.2023.147177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17200
[Journal Article] A Novel Molecular Target in EGFR-mutant Lung Cancer Treated With the Combination of Osimertinib and Pemetrexed2022
- Author(s)
  TAKANO NATSUKI、SEIKE MASAHIRO、SUGANO TEPPEI、MATSUDA KUNIKO、HISAKANE KAKERU、YOSHIKAWA AKIKO、NAKAMICHI SHINJI、NORO RINTARO、GEMMA AKIHIKO
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Issue: 2 Pages: 709-722
- DOI
  10.21873/anticanres.15529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17200
[Journal Article] Long Non-Coding RNA CRNDE Is Involved in Resistance to EGFR Tyrosine Kinase Inhibitor in EGFR-Mutant Lung Cancer via eIF4A3/MUC1/EGFR Signaling2021
- Author(s)
  Takahashi Satoshi、Noro Rintaro、Seike Masahiro、Zeng Chao、Matsumoto Masaru、Yoshikawa Akiko、Nakamichi Shinji、Sugano Teppei、Hirao Mariko、Matsuda Kuniko、Hamada Michiaki、Gemma Akihiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 8 Pages: 4005-4005
- DOI
  10.3390/ijms22084005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15784, KAKENHI-PROJECT-16H05879, KAKENHI-PROJECT-17K20032, KAKENHI-PROJECT-20K17200, KAKENHI-PROJECT-17KK0177
[Journal Article] Inhibitory Effect of Cytoprotective Autophagy Against the Anticancer Activity of Tyrosine Kinase Inhibitors2020
- Author(s)
  Nakajima Wataru、Nakamichi Shinji、Suzuki Hidenori、Tanaka Nobuyuki
- Journal Title
  
  Nihon Ika Daigaku Igakkai Zasshi
  
  Volume: 16 Issue: 4 Pages: 184-185
- DOI
  10.1272/manms.16.184
- NAID
  130007956262
- ISSN
  1349-8975, 1880-2877
- Year and Date
  2020-10-31
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17200
[Presentation] EGFR変異陽性肺がんにおける薬剤耐性獲得機構の解明と代謝制御を利用した治療法開発2023
- Author(s)
  中嶋亘, 石野孔祐, 中道真仁, 松本優, 大橋隆治, 山本林
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K08293
[Presentation] EGFR変異陽性肺がんにおける薬剤耐性獲得機構の解明と代謝制御を利用した治療法開発2023
- Author(s)
  中嶋亘, 石野孔祐, 中道真仁, 松本優, 大橋隆治, 山本林
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K17200
[Presentation] EGFR遺伝子変異陽性非小細胞肺癌に対するオシメルチニブ耐性後のカルボプラチン+ペメトレキセド+アファチニブ併用療法の有効性2023
- Author(s)
  恩田直美, 中道真仁, 松本優, 宮永晃彦, 清家正博
- Organizer
  日本呼吸器学会総会
- Data Source
  KAKENHI-PROJECT-20K17200
[Presentation] EGFR陽性肺癌に対するオシメルチニブ耐性後カルボプラチン+ペメトレキセド+アファチニブ併用の有効性2022
- Author(s)
  恩田直美, 中道真仁, 松本優, 宮永晃彦, 野呂林太郎, 清家正博
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17200
[Presentation] AXL活性化を示すALK 阻害薬耐性肺癌に対するギルテリチニブによる新規治療戦略2022
- Author(s)
  中道真仁、野呂林太郎、平尾真季子、松本優、宮永晃彦、久保田馨、清家正博
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17200
[Presentation] EGFR遺伝子変異陽性肺癌細胞株におけるosimertinibとpemetrexedの併用効果と分子メカニズムの検討2021
- Author(s)
  高野夏希, 清家正博, 大森美和子, 福泉彩, 久金翔, 中道真仁, 菅野哲平, 松本優, 宮永晃彦, 久保田馨, 弦間昭彦
- Organizer
  日本呼吸器学会総会
- Data Source
  KAKENHI-PROJECT-20K17200
[Presentation] https://researchmap.jp/snakamichi/published_papers/349938282021
- Author(s)
  松木覚, 中道真仁, 清水理光, 恩田直美, 菅野哲平, 峯岸裕司, 野呂林太郎, 久保田馨, 清家正博, 弦間昭彦
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-20K17200
[Presentation] P－19 EGFR 変異陽性非小細胞肺がんの EGFR-TKI 抵抗性に伴う SMAD6 過剰発現の分子機構の解析と治療への応用2020
- Author(s)
  宮崎海中嶋亘・田中信之中道真仁・清家正博
- Organizer
  第 88 回日本医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-20K17200

1. 中嶋亘 (40557500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 曽超

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamichi Shinji 中道 真仁

Research Projects

Research Products

Co-Researchers

分子標的薬耐性肺がんにおける薬剤耐性獲得機構の解明と代謝制御を利用した治療法開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel strategy targeting apoptosis regulators for non-small cell lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Afatinib plus PEM and CBDCA overcome osimertinib-resistance in EGFR-mutated NSCLC with high thrombospondin-1 expression2024

Author(s)

Journal Title

Data Source

[Journal Article] Phosphoproteomic Analysis Identified Mutual Phosphorylation of FAK and Src as a Mechanism of Osimertinib Resistance in EGFR-Mutant Lung Cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] nduction of resistance to neurotrophic tropomyosin-receptor kinase inhibitors by HMGCS2 via a mevalonate pathway2024

Author(s)

Journal Title

Data Source

[Journal Article] Serum-derived exosomal miR-125a-3p predicts the response to anti-programmed cell death-1/programmed cell death-ligand 1 monotherapy in patients with non-small cell lung cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Novel Molecular Target in EGFR-mutant Lung Cancer Treated With the Combination of Osimertinib and Pemetrexed2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long Non-Coding RNA CRNDE Is Involved in Resistance to EGFR Tyrosine Kinase Inhibitor in EGFR-Mutant Lung Cancer via eIF4A3/MUC1/EGFR Signaling2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibitory Effect of Cytoprotective Autophagy Against the Anticancer Activity of Tyrosine Kinase Inhibitors2020

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Presentation] EGFR変異陽性肺がんにおける薬剤耐性獲得機構の解明と代謝制御を利用した治療法開発2023

Author(s)

Organizer

Data Source

[Presentation] EGFR変異陽性肺がんにおける薬剤耐性獲得機構の解明と代謝制御を利用した治療法開発2023

Author(s)

Organizer

Data Source

[Presentation] EGFR遺伝子変異陽性非小細胞肺癌に対するオシメルチニブ耐性後のカルボプラチン+ペメトレキセド+アファチニブ併用療法の有効性2023

Author(s)

Organizer

Data Source

[Presentation] EGFR陽性肺癌に対するオシメルチニブ耐性後カルボプラチン+ペメトレキセド+アファチニブ併用の有効性2022

Author(s)

Organizer

Data Source

[Presentation] AXL活性化を示すALK 阻害薬耐性肺癌に対するギルテリチニブによる新規治療戦略2022

Author(s)

Organizer

Data Source

[Presentation] EGFR遺伝子変異陽性肺癌細胞株におけるosimertinibとpemetrexedの併用効果と分子メカニズムの検討2021

Author(s)

Organizer

Data Source

[Presentation] https://researchmap.jp/snakamichi/published_papers/349938282021

Author(s)

Organizer

Nakamichi Shinji 中道真仁