Sakuragi Takaharu 櫻木崇晴

Researcher Number	10867906
Other IDs
Affiliation (Current)	2025: 大阪大学, 免疫学フロンティア研究センター, 特任助教(常勤)
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 免疫学フロンティア研究センター, 特任助教(常勤) 2021 – 2023: 大阪大学, 免疫学フロンティア研究センター, 特任助教(常勤) 2020: 大阪大学, 免疫学フロンティア研究センター, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 43020:Structural biochemistry-related / Basic Section 44010:Cell biology-related Except Principal Investigator Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Keywords	Principal Investigator リン脂質スクランブリング / Xkr8 / スクランブラーゼ / 単粒子解析 / Xkr8-Basigin複合体 / XKR8 / ナノディスク / Basigin / アポトーシス / 'eat me'シグナル / ホスファチジルセリン露出 / 構造解析 / リン脂質スクランブラーゼ … More Except Principal Investigator … More 基質特異性 / 三次構造 / リン脂質 / スクランブラーゼ / フリッパーゼ Less

肥満細胞活性化に伴うホスファチジルセリン露出機構の解明Principal Investigator
- Principal Investigator
  
  櫻木崇晴
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  The University of Osaka
Xkr8によるリン脂質スクランブル過程の可視化Principal Investigator
- Principal Investigator
  
  櫻木崇晴
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Osaka University
Elucidation of the molecular mechanism of scramblase, and the substrate specificity of flippase
- Principal Investigator
  
  NAGATA Shigekazu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Osaka University
The study on mechanism of phospholipid scrambling by Xkr8Principal Investigator
- Principal Investigator
  
  Sakuragi Takaharu
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Osaka University

All 2024 2023 2022 2021

All Journal Article Presentation Book

[Book] 実験医学2022年3月号2022
- Author(s)
  櫻木崇晴、長田重一
- Total Pages
  133
- Publisher
  羊土社
- ISBN
  9784758125536
- Data Source
  KAKENHI-PROJECT-20K15731
[Journal Article] The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase2024
- Author(s)
  Sakuragi Takaharu、Kanai Ryuta、Otani Mayumi、Kikkawa Masahide、Toyoshima Chikashi、Nagata Shigekazu
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 3 Pages: 105755-105755
- DOI
  10.1016/j.jbc.2024.105755
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18106, KAKENHI-PROJECT-22K06102, KAKENHI-PROJECT-21K06109, KAKENHI-PLANNED-21H05248, KAKENHI-PROJECT-21H04770, KAKENHI-PROJECT-23K27136
[Journal Article] Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases2023
- Author(s)
  Sakuragi, T., Nagata, S.
- Journal Title
  
  Nature Reviews Molecular Cell Biology
  
  Volume: 24 Issue: 8 Pages: 576-596
- DOI
  10.1038/s41580-023-00604-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04770
[Journal Article] クライオ電子顕微鏡でリン脂質スクランブリングのしくみに迫る2022
- Author(s)
  櫻木　崇晴、長田　重一
- Journal Title
  
  実験医学
  
  Volume: 40 Pages: 596-599
- Data Source
  KAKENHI-PROJECT-21H04770
[Journal Article] The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes2021
- Author(s)
  Sakuragi Takaharu、Kanai Ryuta、Tsutsumi Akihisa、Narita Hirotaka、Onishi Eriko、Nishino Kohei、Miyazaki Takuya、Baba Takeshi、Kosako Hidetaka、Nakagawa Atsushi、Kikkawa Masahide、Toyoshima Chikashi、Nagata Shigekazu
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 28 Issue: 10 Pages: 825-834
- DOI
  10.1038/s41594-021-00665-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06148, KAKENHI-PROJECT-20K15731, KAKENHI-PROJECT-21H04770, KAKENHI-PROJECT-21K06109, KAKENHI-PROJECT-19H00975
[Presentation] Structural analysis of the XKR8-Basigin complex that scrambles phospholipids at the plasma membrane2022
- Author(s)
  Takaharu Sakuragi, Shigekazu Nagata
- Organizer
  The 29th Federation of Asian and Oceanian Biochemists and Molecular Biologists Conference & the 2022 Chinese Society of Biochemistry and Molecular Biology Online Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06102
[Presentation] 細胞膜リン脂質スクランブラーゼXkr8-Basigin複合体の構造解析2022
- Author(s)
  櫻木　崇晴
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04770
[Presentation] Structural analysis of the XKR8-Basigin complex that scrambles phospholipids at the plasma membrane2022
- Author(s)
  櫻木　崇晴
- Organizer
  The 29th Federation of Asian and Oceanian Biochemists and Molecular Biologists Conference & the 2022 Chinese Society of Biochemistry and Molecular Biology Online Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04770
[Presentation] 細胞膜リン脂質スクランブラーゼXkr8-Basigin複合体の構造解析2022
- Author(s)
  櫻木崇晴, 長田重一
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06102
[Presentation] 細胞膜リン脂質スクランブラーゼであるヒトXkr8-Basigin複合体の立体構造2021
- Author(s)
  櫻木　崇晴
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H04770
[Presentation] The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes2021
- Author(s)
  Sakuragi Takaharu、Kanai Ryuta、Tsutsumi Akihisa、Narita Hirotaka、Onishi Eriko、Nishino Kohei、Miyazaki Takuya、Baba Takeshi、Kosako Hidetaka、Nakagawa Atsushi、Kikkawa Masahide、Toyoshima Chikashi、Nagata Shigekazu
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K15731

1. NAGATA Shigekazu (70114428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 瀬川勝盛 (20542971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KANAI Ryuta

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 豊島近

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakuragi Takaharu 櫻木 崇晴

Research Projects

Research Products

Co-Researchers

肥満細胞活性化に伴うホスファチジルセリン露出機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Xkr8によるリン脂質スクランブル過程の可視化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism of scramblase, and the substrate specificity of flippase

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study on mechanism of phospholipid scrambling by Xkr8Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 実験医学2022年3月号2022

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] クライオ電子顕微鏡でリン脂質スクランブリングのしくみに迫る2022

Author(s)

Journal Title

Data Source

[Journal Article] The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Structural analysis of the XKR8-Basigin complex that scrambles phospholipids at the plasma membrane2022

Author(s)

Organizer

Data Source

[Presentation] 細胞膜リン脂質スクランブラーゼXkr8-Basigin複合体の構造解析2022

Author(s)

Organizer

Data Source

[Presentation] Structural analysis of the XKR8-Basigin complex that scrambles phospholipids at the plasma membrane2022

Author(s)

Organizer

Data Source

[Presentation] 細胞膜リン脂質スクランブラーゼXkr8-Basigin複合体の構造解析2022

Author(s)

Organizer

Data Source

[Presentation] 細胞膜リン脂質スクランブラーゼであるヒトXkr8-Basigin複合体の立体構造2021

Author(s)

Organizer

Data Source

[Presentation] The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes2021

Author(s)

Organizer

Data Source

Sakuragi Takaharu 櫻木崇晴