Usui Yuu 臼居優

Researcher Number	10868615
Other IDs
Affiliation (Current)	2025: 徳島大学, 先端酵素学研究所, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 川崎医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 44040:Morphology and anatomical structure-related / Basic Section 44020:Developmental biology-related Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90110:Biomedical engineering-related
Keywords	Principal Investigator 形態形成 / 心室壁 / 心臓生理学 / 心室拡張機能 / 心臓 / 体表模様形成 / 色素細胞 / スペルミジン / ゼブラフィッシュ Except Principal Investigator 心筋細胞 … More / 再生 / 心不全 / コネクチン / 進化 / 酸素環境 / 心筋 / 酸素 / バネ分子コネクチン / 冠循環 / 心室拡張機能 / 心室拡張能 / 心臓進化 / 心室拡張 / Fam64a / Novex-3 / 核物性 / メカニカルストレス / 力学応答 / 胎児環境 / 分裂・再生 / 胎盤 / ヘモグロビン / 低酸素 / 分裂 Less

Molecular Basis of Tension Sensing Transduction System in Cardiomyocytes and Its Application to Heart Failure
- Principal Investigator
  
  花島章
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kawasaki Medical School
柔軟な核を持つ心筋細胞による革新的心再生戦略の創出
- Principal Investigator
  
  橋本謙
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kawasaki Medical School
生命進化史における酸素トレードオフに立脚した心筋再生への挑戦
- Principal Investigator
  
  橋本謙
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kawasaki Medical School
Biomedical engineering multi-scale ventricular diastolic function analysis to elucidate the pathogenesis of diastolic heart failure
- Principal Investigator
  
  毛利聡
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kawasaki Medical School
心室壁の厚さを最適化して、機能的な心臓を生成する仕組みの解明Principal Investigator
- Principal Investigator
  
  臼居優
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  Kawasaki Medical School
A paradigm shift in fetal oxygen regulation implicated in heart regeneration.
- Principal Investigator
  
  HASHIMOTO Ken
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kawasaki Medical School
The study for mechanism of zebrafish skin pattern pattern formation by spermidinePrincipal Investigator
- Principal Investigator
  
  Usui Yuu
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kawasaki Medical School

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Comparative analysis of ventricular stiffness across species2024
- Author(s)
  Yuu Usui, Akira Hanashima, Ken Hashimoto, Misaki Kimoto, Momoko Ohira, Satoshi Mohri
- Journal Title
  
  Physiol Rep
  
  Volume: 12(8) Issue: 8
- DOI
  10.14814/phy2.16013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19933, KAKENHI-PROJECT-23H00556, KAKENHI-PROJECT-20H04521
[Journal Article] Cardiac hemodynamics and ventricular stiffness of sea-run cherry salmon (Oncorhynchus masou masou) differ critically from those of landlocked masu salmon2022
- Author(s)
  Usui Yuu、Kimoto Misaki、Hanashima Akira、Hashimoto Ken、Mohri Satoshi
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 11 Pages: e0267264-e0267264
- DOI
  10.1371/journal.pone.0267264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15155
[Journal Article] Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf152022
- Author(s)
  Hashimoto K, Kodama A, Ohira M, Kimoto M, Nakagawa R, Usui Y, Ujihara Y, Hanashima A, Mohri S
- Journal Title
  
  iScience
  
  Volume: 25(5) Issue: 5 Pages: 104337-104337
- DOI
  10.1016/j.isci.2022.104337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19933, KAKENHI-PROJECT-20H04521
[Journal Article] 酸素環境と心臓再生（Oxygen environment and cardiac regeneration）2022
- Author(s)
  橋本謙, 臼居優, 花島章, 氏原嘉洋, 塚田孝祐, 毛利聡
- Journal Title
  
  Medical Science Digest
  
  Volume: 48(10)
- Data Source
  KAKENHI-PROJECT-21K19933
[Journal Article] Role of the Connexin C-terminus in skin pattern formation of Zebrafish2021
- Author(s)
  Usui Yuu、Watanabe Masakatsu
- Journal Title
  
  BBA Advances
  
  Volume: 1 Pages: 100006-100006
- DOI
  10.1016/j.bbadva.2021.100006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15803, KAKENHI-PROJECT-19J12372, KAKENHI-PROJECT-17H03683
[Presentation] Atrioventricular hearts and molecular spring connectin in the mollusc oyster.2023
- Author(s)
  Hanashima A, Usui Y, Hashimoto K, Mohri S.
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-23H00556
[Presentation] 軟体動物カキの心臓のメカニクスとバネ分子コネクチン2023
- Author(s)
  花島章、木元弥咲、大平桃子、臼居優、橋本謙、毛利聡
- Organizer
  第62回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-23H00556
[Presentation] 心臓進化：軟体動物カキと脊椎動物の共通性と筋弾性蛋白質コネクチン2023
- Author(s)
  花島章、木元弥咲、大平桃子、臼居優、橋本謙、毛利聡
- Organizer
  日本進化学会第25回大会
- Data Source
  KAKENHI-PROJECT-23H00556
[Presentation] Nuclear connectin novex-3 contributes to fetal cardiomyocyte proliferation by softening nuclei.2023
- Author(s)
  Hashimoto K, Ohira M, Kodama A, Kimoto M, Inoue M, Usui Y, Hanashima A, Ujihara Y, Mohri S.
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-23H00556

1. HASHIMOTO Ken (80341080)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
2. 毛利聡 (00294413)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
3. 花島章 (70572981)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
4. 塚田孝祐 (00351883)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. 氏原嘉洋 (80610021)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results

Usui Yuu 臼居 優

Research Projects

Research Products

Co-Researchers

Molecular Basis of Tension Sensing Transduction System in Cardiomyocytes and Its Application to Heart Failure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

柔軟な核を持つ心筋細胞による革新的心再生戦略の創出

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生命進化史における酸素トレードオフに立脚した心筋再生への挑戦

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Biomedical engineering multi-scale ventricular diastolic function analysis to elucidate the pathogenesis of diastolic heart failure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

心室壁の厚さを最適化して、機能的な心臓を生成する仕組みの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A paradigm shift in fetal oxygen regulation implicated in heart regeneration.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study for mechanism of zebrafish skin pattern pattern formation by spermidinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Comparative analysis of ventricular stiffness across species2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cardiac hemodynamics and ventricular stiffness of sea-run cherry salmon (Oncorhynchus masou masou) differ critically from those of landlocked masu salmon2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf152022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 酸素環境と心臓再生（Oxygen environment and cardiac regeneration）2022

Author(s)

Journal Title

Data Source

[Journal Article] Role of the Connexin C-terminus in skin pattern formation of Zebrafish2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Atrioventricular hearts and molecular spring connectin in the mollusc oyster.2023

Author(s)

Organizer

Data Source

[Presentation] 軟体動物カキの心臓のメカニクスとバネ分子コネクチン2023

Author(s)

Organizer

Data Source

[Presentation] 心臓進化：軟体動物カキと脊椎動物の共通性と筋弾性蛋白質コネクチン2023

Author(s)

Usui Yuu 臼居優