Fujii Kazuki 藤井一希

Researcher Number	10881609
Other IDs
Affiliation (Current)	2025: 富山大学, 学術研究部医学系, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 富山大学, 学術研究部医学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Basic Section 42040:Laboratory animal science-related / 0702:Biology at cellular to organismal levels, and related fields
Keywords	Principal Investigator 神経科学 / AKAP / PKA / 短鎖ペプチド / 時空間制御 / 性差 / ゲノム編集

PKA 局在の負の制御因子が高次脳機能を制御する分子的基盤の解明Principal Investigator
- Principal Investigator
  
  藤井一希
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
- Research Institution
  University of Toyama
Elucidation of the sex-specific roles of PKA-signal endogenous inhibitor in brain functionPrincipal Investigator
- Principal Investigator
  
  Fujii Kazuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  University of Toyama
Elucidation of the physiological function of Akain1, a central nerve system-specific expressed protein kinase A-binding microproteinPrincipal Investigator
- Principal Investigator
  
  Fujii Kazuki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0702:Biology at cellular to organismal levels, and related fields
- Research Institution
  University of Toyama

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia2023
- Author(s)
  Arime Yosefu、Saitoh Yoshito、Ishikawa Mikiko、Kamiyoshihara Chikako、Uchida Yasuo、Fujii Kazuki、Takao Keizo、Akiyama Kazufumi、Ohkawa Noriaki
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 49 Issue: 4 Pages: 720-730
- DOI
  10.1038/s41386-023-01769-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K17422, KAKENHI-PROJECT-23K07042, KAKENHI-PROJECT-20K07925, KAKENHI-PROJECT-21K15006, KAKENHI-PROJECT-19H03538
[Journal Article] ILF3 prion-like domain regulates gene expression and fear memory under chronic stress2023
- Author(s)
  Yamashita Akira、Shichino Yuichi、Fujii Kazuki、Koshidaka Yumie、Adachi Mayumi、Sasagawa Eri、Mito Mari、Nakagawa Shinichi、Iwasaki Shintaro、Takao Keizo、Shiina Nobuyuki
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 3 Pages: 106229-106229
- DOI
  10.1016/j.isci.2023.106229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19281, KAKENHI-PROJECT-21K15006, KAKENHI-PROJECT-18H05213, KAKENHI-PLANNED-21H05274, KAKENHI-PUBLICLY-22H05614, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H03538, KAKENHI-PROJECT-21K15023, KAKENHI-PROJECT-23K23816
[Journal Article] Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome2023
- Author(s)
  Kurabayashi Nobuhiro、Fujii Kazuki、Otobe Yuta、Hiroki Shingo、Hiratsuka Masaharu、Yoshitane Hikari、Kazuki Yasuhiro、Takao Keizo
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 12 Pages: 108379-108379
- DOI
  10.1016/j.isci.2023.108379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18231, KAKENHI-PROJECT-23K17422, KAKENHI-PROJECT-21K15006, KAKENHI-PROJECT-19H03538
[Journal Article] Maternal dietary imbalance between omega-6 and omega-3 fatty acids triggers the offspring’s overeating in mice2020
- Author(s)
  Sakayori N, Katakura M, Hamazaki K, Higuchi O, Fujii K, Fukabori R, Iguchi Y, Setogawa S, Takao K, Miyazawa T, Arita M, & Kobayashi K
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 1-13
- DOI
  10.1038/s42003-020-01209-4
- NAID
  120007169782
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K03381, KAKENHI-PROJECT-19K20184, KAKENHI-PROJECT-20K22650, KAKENHI-PROJECT-18H05213, KAKENHI-PUBLICLY-19H05010, KAKENHI-PUBLICLY-19H05023, KAKENHI-PROJECT-19H03538, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H00495
[Presentation] 糖鎖硫酸基転移酵素 Chst9 欠損マウスは、不安様行動の増加と社会的行動の異常を示す2024
- Author(s)
  藤井一希, 泉川友美, 腰高由美恵, 安達真由美, 柳橋裕子, 本郷翔子, 吉田沙織, 安川二千穂, 高雄啓三
- Organizer
  先端モデル動物支援プラットフォーム 2023年度成果発表会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] lncRNA TUNAR 内の非古典的 ORF 欠損マウスはプレパルス抑制の増強とうつ関連行動の増加を示す2024
- Author(s)
  藤井一希, 森脇雄介, 腰高由美恵, 安達真由美, 柳橋裕子, 本郷翔子, 相澤康則, 高雄啓三
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] 長鎖ノンコーディングRNA Tincrにコードされたユビキチン様タンパク欠損マウスにおける行動表現型解析2023
- Author(s)
  木村公洋、水品純太、藤井一希、腰高由美恵、安達真由美、柳橋裕子、本郷翔子、相澤康則、高雄啓三
- Organizer
  第70回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] 妊娠期における必須脂肪酸の摂取バランスが仔の行動に及ぼす影響の網羅的解析2023
- Author(s)
  酒寄信幸, 藤井一希, 片倉賢紀, 高雄啓三, 杉田誠
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] ILF3 prion-like domain regulates gene expression and fear memory under chronic stress.2023
- Author(s)
  Akira Yamashita, Yuichi Shichino, Kazuki Fujii, Yumie Koshidaka, Mayumi Adachi, Eri Sasagawa, Mari Mito, Shinichi Nakagawa, Shintaro Iwasaki, Keizo Takao, Nobuyuki Shiina
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] Loss of Akain1, an endogenous micropeptide that inhibits PKA localization, attenuates contextual discrimination and behavioral flexibility in mice2023
- Author(s)
  K. FUJII, Y. KOSHIDAKA, M. ADACHI, Y. YANAGIBASHI, M. MATSUO, S. HONGO, H. NISHIZONO, I. TAKASAKI, N. KUROSAWA, Y. AIZAWA, K. TAKAO
- Organizer
  53rd Annual Meeting of Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] プロテインキナーゼA（PKA）結合マイクロプロテインAkain1 欠損マウスは類似条件の分別に異常を示す2023
- Author(s)
  藤井一希, 腰高由美恵, 安達真由美, 柳橋裕子, 松尾美奈, 相澤康則, 高雄啓三
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] Loss of non-canonical ORF within lncRNA TUNAR increased pre-pulse inhibition and depression-related behavior in mice2023
- Author(s)
  藤井一希, 森脇雄介, 腰高由美恵, 安達真由美, 柳橋裕子, 本郷翔子, 相澤康則, 高雄啓三
- Organizer
  文部科学省学術変革領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム成果発表会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] Loss of Akain1, an endogenous micropeptide that inhibits PKA localization, attenuates contextual discrimination and behavioral flexibility in mice2023
- Author(s)
  Kazuki Fujii, Yumie Koshidaka, Mayumi Adachi, Yuko Yanagibashi, Mina Matsuo, Shoko Hongo, Hirofumi Nishizono, Ichiro Takasaki, Nobuyuki Kurosawa, Yasunori Aizawa, Keizo Takao
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] 卵巣摘出処置はC57BL6/J及びAPPノックインマウスのアルツハイマー病関連行動表現型を緩和する2023
- Author(s)
  藤井一希、腰高由美恵、安達真由美、松尾美奈、柳橋裕子、木村公洋、斉藤貴志、西道隆臣、高雄啓三
- Organizer
  第70回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] プロテインキナーゼ A (PKA) 結合配列を持つマイクロプロテイン Akain1 欠損マウスは類似条件弁別障害を示す2022
- Author(s)
  藤井一希, 腰高由美恵, 安達真由美, 柳橋裕子, 松尾美奈, 西園啓文, 黒田信幸, 相澤康則, 高雄啓三
- Organizer
  先端モデル動物支援プラットフォーム 2021年度成果発表会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] Cyclin-dependent kinase-like 5 (CDKL5) キナーゼ活性欠損ノックインマウスの作製と網羅的行動解析2022
- Author(s)
  田中輝幸, 安藤さくら, 阿部学, 崎村健司, 藤井一希, 高雄啓三
- Organizer
  先端モデル動物支援プラットフォーム 2021年度成果発表会
- Data Source
  KAKENHI-PROJECT-20K22650
[Presentation] Loss of non-canonical open reading frame within lncRNA TUNAR increased pre-pulse inhibition and depression-related behavior in mice2022
- Author(s)
  Kazuki Fujii, Yusuke Moriwaki, Yumie Koshidaka, Mayumi Adachi, Yuko Yanagibashi, Shoko Hongo, Yasunori Aizawa, Keizo Takao
- Organizer
  51st Annual meeting of Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] lncRNA TUNAR 内非古典的ORF欠損マウスはプレパルス抑制の増強とうつ関連行動の増加を示す2022
- Author(s)
  藤井一希, 森脇雄介, 腰高由美恵, 安達真由美, 柳橋裕子, 本郷翔子, 相澤康則, 高雄啓三
- Organizer
  第69回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] 免疫グロブリンＡの欠損により免疫および神経機能の破綻2022
- Author(s)
  安達貴弘, 藤井一希, 高雄啓三, 永石宇司
- Organizer
  先端モデル動物支援プラットフォーム 2021年度成果発表会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] The latent neuronal ensembles constructed by Pcdhs function as fundamental units in allocating information2022
- Author(s)
  Mei Hayashi, Hirotaka Asai, Reiko Okubo-Suzuki, Ryosuke Kaneko, Kazuki Fujii, Keizo Takao, Takeshi Yagi, Kaoru Inokuchi
- Organizer
  第45回日本神経科学大会 NEURO 2022
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] Arf GEF, GAPファミリーmRNAの神経樹状突起局在制御がシナプス形成に与える影響2022
- Author(s)
  大橋りえ、藤井一希、高雄啓三、椎名伸之
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] プロテインキナーゼ A (PKA) 結合配列を持つマイクロプロテイン Akain1 欠損マウスは類似条件弁別障害を示す2022
- Author(s)
  藤井一希, 腰高由美恵, 安達真由美, 柳橋裕子, 松尾美奈, 西園啓文, 黒田信幸, 相澤康則, 高雄啓三
- Organizer
  先端モデル動物支援プラットフォーム 2021年度成果発表会
- Data Source
  KAKENHI-PROJECT-20K22650
[Presentation] Dietary imbalance in polyunsaturated fatty acids during pregnancy affects dopaminergic neurogenesis in their embryos and is associated with offspring's various behavioral abnormalities2022
- Author(s)
  Nobuyuki Sakayori, Kazuki Fujii, Masanori Katakura, Kazuto Kobayashi, Keizo Takao, Makoto Sugita
- Organizer
  第45回日本神経科学大会 NEURO 2022
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] 免疫グロブリンＡの欠損により免疫および神経機能の破綻2022
- Author(s)
  安達貴弘, 藤井一希, 高雄啓三, 永石宇司
- Organizer
  先端モデル動物支援プラットフォーム 2021年度成果発表会
- Data Source
  KAKENHI-PROJECT-20K22650
[Presentation] Cyclin-dependent kinase-like 5 (CDKL5) キナーゼ活性欠損ノックインマウスの作製と網羅的行動解析2022
- Author(s)
  田中輝幸, 安藤さくら, 阿部学, 崎村健司, 藤井一希, 高雄啓三
- Organizer
  先端モデル動物支援プラットフォーム 2021年度成果発表会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] A novel therapeutic strategy for cognitive dysfunctions under clinically relevant antipsychotic treatment in a mouse model of schizophrenia2022
- Author(s)
  Yosefu Arime, Yoshito Saitoh, Yasuo Uchida, Mikiko Ishikawa, Chikako Kamiyoshihara, Kazuki Fujii, Keizo Takao, Noriaki Ohkawa
- Organizer
  第45回日本神経科学大会 NEURO 2022
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] Loss of non-canonical open reading frame within lncRNA TUNAR increased pre-pulse inhibition and depression-related behavior in mice2022
- Author(s)
  Kazuki Fujii, Yusuke Moriwaki, Yumie Koshidaka, Mayumi Adachi, Yuko Yanagibashi, Shoko Hongo, Yasunori Aizawa, Keizo Takao
- Organizer
  第45回日本神経科学大会 NEURO 2022
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] Chemogenetic activation of prefrontal parvalbumin interneurons in combination with clinically comparable antipsychotic treatment restores working memory deficits in a mouse model of schizophrenia.2021
- Author(s)
  Yosefu Arime, Yoshito Saitoh, Yasuo Uchida, Mikiko Ishikawa, Chikako Kamiyoshihara, Kazuki Fujii, Keizo Takao, Noriaki Ohkawa
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K15006
[Presentation] Chemogenetic activation of prefrontal parvalbumin interneurons in combination with clinically comparable antipsychotic treatment restores working memory deficits in a mouse model of schizophrenia.2021
- Author(s)
  Yosefu Arime, Yoshito Saitoh, Yasuo Uchida, Mikiko Ishikawa, Chikako Kamiyoshihara, Kazuki Fujii, Keizo Takao, Noriaki Ohkawa
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K22650
[Presentation] 共母体免疫活性化は胎児の脳における Ptprd 遺伝子微小エクソン選択調節を撹乱する．2020
- Author(s)
  藤村耕平，仙道水月，藤井一希，吉田知之，高雄啓三.
- Organizer
  第67回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-20K22650
[Presentation] 非調和解析（ＮＨＡ）を用いたマウス呼吸の時間周波数解析．2020
- Author(s)
  淺野雄輝，藤井一希，長谷川昌也，廣林茂樹，高雄啓三．
- Organizer
  第67回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-20K22650

1. TAKAO Keizo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. IGUCHI Yoshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. YOSHITANE Hikari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 椎名伸之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujii Kazuki 藤井 一希

Research Projects

Research Products

Co-Researchers

PKA 局在の負の制御因子が高次脳機能を制御する分子的基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the sex-specific roles of PKA-signal endogenous inhibitor in brain functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the physiological function of Akain1, a central nerve system-specific expressed protein kinase A-binding microproteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ILF3 prion-like domain regulates gene expression and fear memory under chronic stress2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Maternal dietary imbalance between omega-6 and omega-3 fatty acids triggers the offspring’s overeating in mice2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] 糖鎖硫酸基転移酵素 Chst9 欠損マウスは、不安様行動の増加と社会的行動の異常を示す2024

Author(s)

Organizer

Data Source

[Presentation] lncRNA TUNAR 内の非古典的 ORF 欠損マウスはプレパルス抑制の増強とうつ関連行動の増加を示す2024

Author(s)

Organizer

Data Source

[Presentation] 長鎖ノンコーディングRNA Tincrにコードされたユビキチン様タンパク欠損マウスにおける行動表現型解析2023

Author(s)

Organizer

Data Source

[Presentation] 妊娠期における必須脂肪酸の摂取バランスが仔の行動に及ぼす影響の網羅的解析2023

Author(s)

Organizer

Data Source

[Presentation] ILF3 prion-like domain regulates gene expression and fear memory under chronic stress.2023

Author(s)

Organizer

Data Source

[Presentation] Loss of Akain1, an endogenous micropeptide that inhibits PKA localization, attenuates contextual discrimination and behavioral flexibility in mice2023

Author(s)

Organizer

Data Source

[Presentation] プロテインキナーゼA（PKA）結合マイクロプロテインAkain1 欠損マウスは類似条件の分別に異常を示す2023

Author(s)

Organizer

Data Source

[Presentation] Loss of non-canonical ORF within lncRNA TUNAR increased pre-pulse inhibition and depression-related behavior in mice2023

Author(s)

Organizer

Data Source

[Presentation] Loss of Akain1, an endogenous micropeptide that inhibits PKA localization, attenuates contextual discrimination and behavioral flexibility in mice2023

Author(s)

Organizer

Data Source

[Presentation] 卵巣摘出処置はC57BL6/J及びAPPノックインマウスのアルツハイマー病関連行動表現型を緩和する2023

Fujii Kazuki 藤井一希

[Presentation] プロテインキナーゼ A (PKA) 結合配列を持つマイクロプロテイン Akain1 欠損マウスは類似条件弁別障害を示す2022

[Presentation] lncRNA TUNAR 内非古典的ORF欠損マウスはプレパルス抑制の増強とうつ関連行動の増加を示す2022

[Presentation] プロテインキナーゼ A (PKA) 結合配列を持つマイクロプロテイン Akain1 欠損マウスは類似条件弁別障害を示す2022

[Presentation] 共母体免疫活性化は胎児の脳における Ptprd 遺伝子微小エクソン選択調節を撹乱する．2020