AOKI Takashi 青木孝

Researcher Number	20053283
External Links
Affiliation (based on the past Project Information) *help	2009 – 2010: 順天堂大学, 医学部, 教授 1995 – 2007: 順天堂大学, 医学部, 教授 1992 – 1993: 順天堂大学, 医学部, 教授 1990: Juntendo Univ. Parasitol. Professor, 医学部, 教授 1989: 順天堂大学, 医学部, 助教授 1987: Juntendo University School of Medicine, 医学部・寄生虫学講座, 助教授 1986: 順天堂大, 医学部, 助教授
Review Section/Research Field	Principal Investigator 寄生虫学(含医用動物学） / 寄生虫学(含医用動物学) / Parasitology (including Sanitary zoology) Except Principal Investigator Chemical pharmacy / Sociology
Keywords	Principal Investigator Trypanosoma / Acivicin / トリパノソーマ / c-FLIP / Crithidia / Leishmania / Allopurinol / AZT / Trypanosoma cruzi / ピリミジンヌクレオチド … More Except Principal Investigator Trypanosoma cruzi / ネズミマラリア原虫 / ミトコンドリア / 呼吸鎖 / 抗マラリア剤 / 生化学 / sesquiterpene lactone / トリパノソーマ / Alpinia galanga / Laurus nobilis / Desmos dasymachalus / dasymachaline-N-oxide / monoterpene / trypanosomiasis / terpenoid / Chenopodium ambrosioides / hydroperoxide / リスク認知 / リスク回避 / 教育的介入 / リスク評価 / 政策への信頼・協力 / HeLa infection assay / natural medicine / Vietnam / 1′-acetoxychavicol acetate / dasymacharine-N-oxide / 天然薬物 / ローレル / Hela infection assay / natural medicines / Michelia alba / HeLa細胞 / β-resorcylic acid ester / limonene / terpineol / epimastigote / Michelea alba / HeLa cell Less

新型インフルエンザ; リスク認知とリスク回避行動の関係についての実証的研究
- Principal Investigator
  
  TSUBOUCHI AKIKO
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Sociology
- Research Institution
  Juntendo University
TRYPANASOMAGRUZI : MOLECULAR BASES FOR INTRACELLULAR PARASITISM, PROLIFERATION, AND PATHOGENICITY IN INFECTED HUMAN CELLSPrincipal Investigator
- Principal Investigator
  
  AOKI Takashi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Juntendo University
MOLECULAR STRATEGIES OF TRYPANOSOMA CRUZI IN REMODELING AND CONTROLLING THE INFECTED HOST CELLSPrincipal Investigator
- Principal Investigator
  
  AOKI Takashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  JUNTENDO UNIVERSITY
Molecular characterization of all the six enzymes and their corresponding genes involved in de novo pyrimidine biosynthesis in trypanosomatidsPrincipal Investigator
- Principal Investigator
  
  AOKI Takashi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Juntendo University
Development of Anti-trypanosomal Drugs Based on Terpene Structure as an Active Unit
- Principal Investigator
  
  KIUCHI Fumiyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
ネズミマラリア原虫ミトコンドリア呼吸鎖成分の生化学解析
- Principal Investigator
  
  高宮信三郎
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Juntendo University
A Search for Naturally Occurring Anti-trypanosomal Compounds Using a HeLa Cell Infection Assay System
- Principal Investigator
  
  KIUCHI Fumiyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
ネズミマラリア原虫ミトコンドリア呼吸鎖成分の生化学的解析
- Principal Investigator
  
  高宮信三郎
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Juntendo University
ネズミマラリア原虫ミトコンドリア呼吸鎖成分の生化学的解析
- Principal Investigator
  
  TAKAMIYA Shinzaburo
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
Molecular characterization of CPS II and ACT genes form Trypanosoma cruziPrincipal Investigator
- Principal Investigator
  
  AOKI Takashi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Juntendo University
Establishment of an in vitro screening system for anti-Trypanosoma cruzi agentsPrincipal Investigator
- Principal Investigator
  
  AOKI Takashi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Juntendo University
Molecular and biochemical studies on the enzymes of nucleic acid precursor synthesis unique to trypanosomatid parasitesPrincipal Investigator
- Principal Investigator
  
  AOKI Takashi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  寄生虫学(含医用動物学）
- Research Institution
  Juntendo University School of Medicine
Biosynthesis of Nucleic Acid Precursors and Its Inhibition in Trypanosomatid ParasitesPrincipal Investigator
- Principal Investigator
  
  AOKI Takashi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学）
- Research Institution
  Juntendo University School of Medicine
Comparative studies on pyrimidine nucleotide biosynthesis characteristic of parasitic protozoaPrincipal Investigator
- Principal Investigator
  
  AOKI Takashi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学）
- Research Institution
  Juntendo University School of Medicine

All 2010 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] ハリソン内科学(原著第16版), Part 6感染症, Section 17〜19(第192〜204章)(監訳)福井次矢・黒川清(日本語版監修)2006
- Author(s)
  青木孝
- Total Pages
  83
- Publisher
  メディカル・サイエンス・インターナショナル,東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Book] ハリソン内科学(原著第16版)、Part 6 感染症、Section 17-19(第192-204章)(監訳) 福井次矢, 黒川清(日本語版監修)2006
- Author(s)
  青木孝
- Total Pages
  83
- Publisher
  メディカル・サイエンス・インターナショナル、東京
- Data Source
  KAKENHI-PROJECT-17390123
[Book] Metabolism of parasitic protozoa. In Progress of Medical Parasitology in Japan, Vol.7 (edited by M Otsuru et al.) Chapter III.2003
- Author(s)
  Aoki T
- Publisher
  Megro Parasitological Museum, Tokyo
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Evolutionary analysis of synteny and gene fusion for pyrimidine biosyntheticenzymes in Euglenozoa:the gap between kinetoplastids and diplonemids2008
- Author(s)
  Makiuchi T, Annoura T, Hashimoto T, Murata E, Aoki T, Nara T
- Journal Title
  
  Protist (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Evolutionary analysis of synteny and gene fusion for pyrimidine biosynthetic enzymes in Euglenozoa : an extraordinary gap between kinetoplastids and diplonemids2008
- Author(s)
  Makiuchi, T., Annoura, T., Hashimoto, T., Murata, E., Aoki, T., Nara, T
- Journal Title
  
  Protist (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Evolutionary analysis of synteny and gene fusion for pyrimidine biosynthetic enzymes in Euglenozoa:the gap between kinetoplastids and diplonemids2008
- Author(s)
  Makiuchi T, Annoura T, Hashimoto T, Murata E, Aoki T, Nara T
- Journal Title
  
  Protist (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Transcriptome profile of Trypanosoma cruzrinfected cells : simultaneous up- and down-regulation of proliferation inhibitors and promoters2008
- Author(s)
  Shigihara, T., Hashimoto, M., Shindo, N., Aoki, T
- Journal Title
  
  Parasitol Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Transcriptome profile of Trypanosoma cruzi-infected cells:simultaneous up-and down-regulation of proliferation inhibitors and promoters2008
- Author(s)
  Shigihara T, Hashimoto M, Shindo N, Aoki T
- Journal Title
  
  Parasitology Research (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Dihydroorotate dehydrogenase arises from novel fused gene product with aspartate carbamoyltransferase in Bodo saliens2007
- Author(s)
  Annoura T, Sariego I, Nara T, Makiuchi T, Fujimura T, Taka H, Mineki R, Murayama K, Aoki T
- Journal Title
  
  Biochemical and Biophysical Research Communications 358
  
  Pages: 253-258
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Occurrence of multiple,independent gene fusion events for the fifth and sixth enzymes of pyrimidine biosynthesis in different eukaryotic groups2007
- Author(s)
  Makiuchi T, Nara T, Annoura T, Hashimoto T, Aoki T
- Journal Title
  
  Gene 394
  
  Pages: 78-86
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Dihydroorotate dehydrogenase arises from novel fused gene product with aspartate carbamoyl-transferase in Bodo saliens2007
- Author(s)
  Annoura, T., Sariego, I., Nara, T., Makiuchi, T., Fujimura, T., Taka, H., Mineki, R, Murayama, K., Aoki, T
- Journal Title
  
  Biochem Biophys Res Comm un 358
  
  Pages: 253-258
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Dihydroorotate dehydrogenase arises from novel fused gene product with aspartate carbamoyltransferase in Bodo saliensfus2007
- Author(s)
  Annoura T, Sariego I, Nara T, Makiuchi T, Fujimura T, Taka H, Mineki R, Murayama K, Aoki T
- Journal Title
  
  Biochemical and Biophysical ResearchCommunications 358
  
  Pages: 253-258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Antibody isotype responses to paramyosin, a vaccine candidate for schistosomiasis, and their correlations with resistance and fibrosis in patients infected with Schistosomiasis japonicum in Leyte, The Philippines2007
- Author(s)
  Nara T, Iizumi K, Ohmae H, Sy OS, Tsubota S, Inaba Y, Tsubouchi A, Tanabe M, Kojima S, Aoki T
- Journal Title
  
  American Journal of Tropical Medicine and Hygiene 76
  
  Pages: 384-391
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Occurrence of multiple, independent gene fusion events for the fifth and sixth enzymes of pyrimidine biosynthesis in different eukaryotic groups2007
- Author(s)
  Makiuchi, T., Nara, T., Annoura, T., Hashimoto, T., Aoki, T
- Journal Title
  
  Gene 394
  
  Pages: 78-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Genetic diversity and kinetic properties of Trypanosoma cruzi dihydroorotate dehydrogenase isoforms2006
- Author(s)
  Sariego I, Annoura T, Nara T, Hashimoto M, Tsubouchi A, Iizumi K, Makiuchi T, Murata E, Kita K, Aoki T
- Journal Title
  
  Parasitology International 55
  
  Pages: 11-16
- NAID
  10017321391
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Molecular cloning and characterization of ouabain-insensitive Na+-ATPase in the parasitic protist, Trypanosoma cruzi2006
- Author(s)
  Iizumi, K., Mikami, Y., Hashimoto, M., Nara, T., Hara, Y., Aoki
- Journal Title
  
  Biochim BiophysActa Biomembranes 1758
  
  Pages: 738-746
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Molecular cloning and characterization of ouabain-insensitive Na^+-ATPase in the parasitic protist, Trypanosoma cruzi2006
- Author(s)
  Iizumi K, Mikami Y, Hashimoto M, Nara T, Hara Y, Aoki T
- Journal Title
  
  Biochimica et Biophysica Acta-Biomembranres 1758
  
  Pages: 738-746
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Molecular cloning and characterization of ouabain-insensitive Na^+-ATPase in the parasitic protist,Trypanosoma cruzi2006
- Author(s)
  Iizumi K, Mikami Y, Hashimoto M, Nara T, Hara Y, Aoki T
- Journal Title
  
  Biochimica et Biophysica Acta-Biomembranres 1758
  
  Pages: 738-746
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Genetic diversity and kinetic properties of Trypanosoma cruzi dihydroorotate dehydrogenase isoforms2006
- Author(s)
  Sariego, I., Annoura, T., Nara, T., Hashimoto, M., Tsubouchi, A., Iizumi, K., Makiuchi, T., Murata, E., Kita, K., Aoki, T
- Journal Title
  
  Parasitollnt 55
  
  Pages: 11-16
- NAID
  10017321391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Antichagasic activity of komaroviquinone is due to generation of reactive oxygen species catalyzed by Trypanosoma cruzi old yellow enzyme2005
- Author(s)
  Uchiyama N, Kabututu Z, Kubata BK, Kiuchi F, Ito M, Nakajima-Shimada J, Aoki T, Ohkubo K, Fukuzumi S, Martin SK, Honda G, Urade Y
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 49
  
  Pages: 5123-5126
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Expression, purification and crystallization of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with orotate2005
- Author(s)
  Inaoka, DK., Takashima, E., Osanai, A., Shimizu, H., Nara, T., Aoki, T., Harada, S., Kita, K
- Journal Title
  
  Acta Cryst F61
  
  Pages: 875-878
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Expression,purification and crystallization of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with orotate2005
- Author(s)
  Inaoka DK, Takashima E, Osanai A, Shimizu H, Nara T, Aoki T, Harada S, Kita K
- Journal Title
  
  Acta Crystallographica F61
  
  Pages: 875-878
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Gene expression profiles in response to Fas stimulation in Trypanosoma cruzi-infected host cells2005
- Author(s)
  Hashimoto M, Nakajima-Shimada J, Ishidoh K, Aoki T
- Journal Title
  
  International Journal for Parasitology 35
  
  Pages: 1587-1594
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] The origin of dihydroorotate dehydrogenase genes of kinetoplastids, with special reference to their biological significance and adaptation to anaerobic, parasitic conditions2005
- Author(s)
  Annoura, T., Nara, T., Makiuchi, T., Hashimoto, T., Aoki, T
- Journal Title
  
  JMol Evol 60
  
  Pages: 113-127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Inhibitory action of marine algae extracts on the Trypanosoma cruzi dihydroorotate dehydro-genase activity and on the protozoan growth in mammalian cells.2005
- Author(s)
  Nara T, Kamei Y, Tsubouchi A, Annoura T, Hirota K, Iizumi K, Dohmoto Y, Ono T, Aoki T
- Journal Title
  
  Parasitol Int 54
  
  Pages: 59-64
- NAID
  10015455204
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Inhibitory action of marine algae extracts on the Trypanosoma cruzi dihydroorotate dehydrogenase activity and on the protozoan growth in mammalian cells2005
- Author(s)
  Nara T, Kamei Y, Tsubouchi A, Annoura T, Hirota K, Iizumi K, Dohmoto Y, Ono T, Aoki T
- Journal Title
  
  Parasitology International 54
  
  Pages: 59-64
- NAID
  10015455204
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] The origin of dihydroorotate dehydrogenase genes of kinetoplastids,with special reference to their biological significance and adaptation to anaerobic,parasitic conditions2005
- Author(s)
  Annoura T, Nara T, Makiuchi T, Hashimoto T, Aoki T
- Journal Title
  
  Journal of Molecular Evolution 60
  
  Pages: 113-127
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Trypanosoma cruzi post-transcriptionally upregulates and exploits cellular FLIP for inhibition of death-inducing signal2005
- Author(s)
  Hashimoto, M., N.-Shimada, J., Aoki, T
- Journal Title
  
  Mol Biol Cell 16
  
  Pages: 3521-3528
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Gene Expression profiles in response to Fas stimulation in Trypanosoma cruzrinfected host cells2005
- Author(s)
  Hashimoto, M., Nakajima-Shimada, J., Ishidoh, K., Aoki, T
- Journal Title
  
  Int J Parasitol 35
  
  Pages: 1587-1594
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Inhibitory action of marine algae extracts on the Trypanosoma cruzi dihydroorotate dehydrogenase activity and on the protozoan growth in mammalian cells2005
- Author(s)
  Nara T, Kamei Y, Tsubouchi A, Annoura T, Hirota K, Iizumi K, Dohmoto Y, Ono T, Aoki T
- Journal Title
  
  Parasitology International 54
  
  Pages: 59-64
- NAID
  10015455204
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] The origin of dihydroorotate dehydrogenase genes of kinetoplastids, with special reference to their biological significance and adaptation to anaerobic, parasitic conditions.2005
- Author(s)
  Annoura T, Nara T, Makiuchi T, Hashimoto T, Aoki T
- Journal Title
  
  J Mol Evol 60
  
  Pages: 113-127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Trypanosoma cruzi posttranscriptionally up-regulates and exploits cellular FLIP for inhibition of death-inducing signal2005
- Author(s)
  Hashimoto M, N.-Shimada J, Aoki T
- Journal Title
  
  Molecular Biology of the Cell 16
  
  Pages: 3521-3528
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Trypanosoma cruzi post-transcriptionally upregulates cellular FLIP for inhibition of death-inducing signal2005
- Author(s)
  Hashimoto M, N.-Shimada J, Aoki T
- Journal Title
  
  Molecular Biology of the Cell (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Trypanosome cruzi posttranscriptionally up-regulates and exploits cellular FLIP for inhibition of death-inducing signal2005
- Author(s)
  Hashimoto M, N.-Shimada J, Aoki T
- Journal Title
  
  Molecular Biology of the Cell 16
  
  Pages: 3521-3528
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] The origin of dihydroorotate dehydrogenase genes of kinetoplastids, with special reference to their biological significance and adaptation to anaerobic, parasitic conditions2005
- Author(s)
  Annoura T, Nara T, Makiuchi T, Hashimoto T, Aoki T
- Journal Title
  
  Journal of Molecular Evolution 60
  
  Pages: 113-127
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Inhibitory action of marine algae extracts on the Trypanosoma cruzi dihydroorotate dehydrogenase and on the protozoan growth in mammalian cells2005
- Author(s)
  Nara T, Kamei Y, Tsubouchi A, Annoura T, Hirota K, Iizumi K, Dohmoto Y, Ono T, Aoki T
- Journal Title
  
  Parasitology International 54
  
  Pages: 59-64
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Antichagasic activity of komaroviquinone is due to generation of reactive oxygen species catalyzed by Trypanosoma cruzi old yellow enzyme2005
- Author(s)
  Uchiyama, N., Kabututu, Z., Kubata, BK., Kiuchi, F., Ito, M., Nakajima-Shimada, J., Aoki, T., Ohkubo, K., Fukuzumi, S., Martin, SK., Honda, G., Urade, Y
- Journal Title
  
  Antimicrob Agents Chemother 49
  
  Pages: 5123-5126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Expression, purification and crystallization of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with orotate2005
- Author(s)
  Inaoka DK, Takashima E, Osanai A, Shimizu H, Nara T, Aoki T, Harada S, Kita K
- Journal Title
  
  Acta Crystallographica F61
  
  Pages: 875-878
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] The origin of dihydroorotate dehydrogenase genes of kinetoplastids, with special reference to their biological significance and adaptation to anaerobic, parasitic conditions2005
- Author(s)
  Annoura T, Nara T, Makiuchi T, Hashimoto T, Aoki T
- Journal Title
  
  Journal of Molecular Evolution 50
  
  Pages: 112-127
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] The origin of dihydroorotate dehydrogenase genes of kinetoplastids, with special reference to their biological significance and adaptation to anaerobic, parasitic conditions2005
- Author(s)
  Annoura T, Nara T, Makiuchi T, Hashimoto T, Aoki T
- Journal Title
  
  Journal of Molecular Evolution 60
  
  Pages: 113-127
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Inhibitory action of marine algae extracts on the Trypanosoma cruzi dihydroorotate dehydrogenase activity and on the protozoan growth in mammalian cells2005
- Author(s)
  Nara, T., Kamei, Y., Tsubouchi, A., Annoura, T., Hirota, K., Iizumi, K., Dohmoto, Y, Ono, T., Aoki, T
- Journal Title
  
  Parasitollnt 54
  
  Pages: 59-64
- NAID
  10015455204
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390123
[Journal Article] Trypanosoma cruzi抗原と作用するヒト心筋細胞タンパク質のファージディスプレイ法による解析2004
- Author(s)
  吉田彩子, 奈良武司, 青木孝
- Journal Title
  
  第73回日本寄生虫学会大会プログラム・抄録集
  
  Pages: 60-60
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Inhibition of Trypanosome cruzi growth in mammalian cells by nimodipine, with low cytotoxicity to host cells2004
- Author(s)
  Hirota K, Tsubouchi A, N.-Shimada J, Nara T, Aoki T
- Journal Title
  
  Tropical Medicine and Health 32
  
  Pages: 181-188
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Inhibition of Trypanosoma cruzi growth in mammalian cells by nimodipine, with low cytotoxicity to host cells2004
- Author(s)
  Hirota K, Tsubouchi A, N.-Shinada J, Nara T, Aoki T
- Journal Title
  
  Tropical Medicine and Health 32
  
  Pages: 181-188
- NAID
  10013297272
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Inhibition of Trypanosoma cruzi growth in mammalian cells by nimodipine, with low cytotoxicity to host cells.2004
- Author(s)
  Hirota K, Tsubouchi A, N.-Shimada J, Nara T, Aoki T
- Journal Title
  
  Trop Med Health 32
  
  Pages: 181-188
- NAID
  10013297272
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Trypanosoma cruzi抗原と作用するヒト心筋細胞タンパク質のファージデイスプレイ法による解析2004
- Author(s)
  吉田彩子, 奈良武司, 青木孝
- Journal Title
  
  第73回日本寄生虫学会大会プログラム・抄録集
  
  Pages: 60-60
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Trypanocidal constituents from Michelia alba.2003
- Author(s)
  Asaruddin MR, Honda G, Tsubouchi A, Nakajima-Shimada J, Aoki T, Kiuchi F
- Journal Title
  
  Natural Medicines 57
  
  Pages: 61-63
- NAID
  110008732240
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Critical contribution of CD28-CD80/CD86 costimulatory pathway to protection from Trypanosoma cruzi infection.2003
- Author(s)
  Miyahira Y, Katae M, Kobayashi S, Takeuchi T, Fukuchi Y, Abe R, Okumura K, Yagita H, Aoki T
- Journal Title
  
  Infect Immun 71
  
  Pages: 3131-3137
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Metabolism parasitic protozoa2003
- Author(s)
  Aoki T
- Journal Title
  
  Progress of Medical Parasitology in Japan (edited by M Otsuru et al.)(Megro Parasitological Museum, Tokyo) Vol.7,Chapter III
  
  Pages: 175-191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Critical contribution of CD28-CD80/CD86 costimulatory pathway to protection from Trypanosoma cruzi infection2003
- Author(s)
  Miyahira Y, Katae M, Kobayashi S, Takeuchi T, Fukuchi Y, Abe R, Okumura K, Yagita H, Aoki T
- Journal Title
  
  Infect Immun 71
  
  Pages: 3131-3137
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Trypanocidal constituents from Michelia alba2003
- Author(s)
  Asaruddin MR.Honda G, Tsubouchi A, N.-Shinada J, Aoki T, Kiuchi F
- Journal Title
  
  Natural Medicines 57
  
  Pages: 61-63
- NAID
  110008732240
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Diversity of aspartate carbamoyltransferase genes of Trypanosoma cruzi2003
- Author(s)
  Nara T, Hirayama-Noguchi Y, Gao G, Murai E, Annoura T, Aoki T
- Journal Title
  
  Int J Parasitol 33
  
  Pages: 845-852
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Diversity of aspartate carbamoyltransferase genes of Trypanosoma cruzi.2003
- Author(s)
  Nara T, Hirayama-Noguchi Y, Gao G, Murai E, Annoura T, Aoki T
- Journal Title
  
  Int J Parasitol 33
  
  Pages: 845-852
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Trypanosoma cruzi post-transcriptionally upregulates cellular FLIP for inhibition of death-inducing signal.
- Author(s)
  Hashimoto M, N.-Shimada J, Aoki T
- Journal Title
  
  Mol Biol Cell (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390138
[Journal Article] Occurrence of multiple, independent gene fusion events for the fifth and sixth enzymes of pyrimidine biosynthesis in different eukaryotic groups
- Author(s)
  Makiuchi T, Nara T, Annoura T, Hashimoto T, Aoki T
- Journal Title
  
  Gene (in press)
- Data Source
  KAKENHI-PROJECT-17390123
[Presentation] Evolutionary analysis of synteny and gene fusion for pyrimidine biosynthetic enzymes in Euglenozoa : An extraordinary gap between kinetoplastids and diplonemids2010
- Author(s)
  Makiuchi T, Annoura T, Hashimoto T, Aoki T, Nara T
- Organizer
  XIIth International Congress of Parasitology (ICOPA)
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-21653043

1. SHIMADA Junko (20211964)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
2. TAKAMIYA Shinzaburo (90138206)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. NARA Takeshi (40276473)

# of Collaborated Projects: 5 results

# of Collaborated Products: 37 results
4. SHIMOGAWARA Rieko (50146776)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TSUBOUCHI AKIKO (10398662)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. KIUCHI Fumiyuki (60161402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAMASAKI Hiroshi (00138207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHIDA Ayako (20343486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. HASHIMOTO Muneaki (30407308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
10. ANNOURA TAKESHI (90407239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
11. KITA Kiyoshi (90134444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 丸井英二 (30111545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AOKI Takashi 青木 孝

Research Projects

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Co-Researchers

新型インフルエンザ; リスク認知とリスク回避行動の関係についての実証的研究

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TRYPANASOMAGRUZI : MOLECULAR BASES FOR INTRACELLULAR PARASITISM, PROLIFERATION, AND PATHOGENICITY IN INFECTED HUMAN CELLSPrincipal Investigator

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MOLECULAR STRATEGIES OF TRYPANOSOMA CRUZI IN REMODELING AND CONTROLLING THE INFECTED HOST CELLSPrincipal Investigator

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Molecular characterization of all the six enzymes and their corresponding genes involved in de novo pyrimidine biosynthesis in trypanosomatidsPrincipal Investigator

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Development of Anti-trypanosomal Drugs Based on Terpene Structure as an Active Unit

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ネズミマラリア原虫ミトコンドリア呼吸鎖成分の生化学解析

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A Search for Naturally Occurring Anti-trypanosomal Compounds Using a HeLa Cell Infection Assay System

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ネズミマラリア原虫ミトコンドリア呼吸鎖成分の生化学的解析

Principal Investigator

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ネズミマラリア原虫ミトコンドリア呼吸鎖成分の生化学的解析

Principal Investigator

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Molecular characterization of CPS II and ACT genes form Trypanosoma cruziPrincipal Investigator

Principal Investigator

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Establishment of an in vitro screening system for anti-Trypanosoma cruzi agentsPrincipal Investigator

Principal Investigator

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Molecular and biochemical studies on the enzymes of nucleic acid precursor synthesis unique to trypanosomatid parasitesPrincipal Investigator

Principal Investigator

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Biosynthesis of Nucleic Acid Precursors and Its Inhibition in Trypanosomatid ParasitesPrincipal Investigator

Principal Investigator

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Comparative studies on pyrimidine nucleotide biosynthesis characteristic of parasitic protozoaPrincipal Investigator

AOKI Takashi 青木孝