HIRAI Kazumitsu 平井和光

Researcher Number	20093940
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2005: 鳥取大 2004: 国立大学法人鳥取大学, 医学部, 教授 1991 – 2003: 鳥取大学, 医学部, 教授 1994: 鳥取大学, 医学, 助教授 1987 – 1990: Ehime University Associate Professor, 医学部, 助教授 1986: 愛媛大, 医学部, 助教授
Review Section/Research Field	Principal Investigator 寄生虫学(含医用動物学) / 寄生虫学(含医用動物学） / Parasitology (including Sanitary zoology) Except Principal Investigator 寄生虫学(含医用動物学) / Parasitology (including Sanitary zoology) / Humanities and Social Sciences
Keywords	Principal Investigator マンソン裂頭条虫 / 成長ホルモン / 擬充尾虫 / 成長因子 / マクロファージ / TNF-α / Spirometra erinaceieuropaei / Growth hormone / Plerocercoid / 成長ホルモン様物質 … More / Growth hormone-like substance / Spirometra erinacei / Macrophage / 生理活性物質 / Growth factor / サイトカイン / Growth hormone receptor / Hepatocyte growth factor / 成長ホルモン受容体アフィニティクロマトグラフィ / 肝細胞初代培養 / 成長促進 / ヒト成長ホルモンモノクロナ-ル抗体 / 初代培養肝細胞増殖活性 / 成長ホルモン受容体 / 肝細胞増殖因子 / 成長ホルモン様物貭 / Human Growth Hormone-Radioreceptor Assay / Growth Factor / ラジオリセプター・アッセイ / 成長促進因子 / ヒト成長ホルモンーラジオリセプターアッセイ / Bioactive substances / Cyclooxygenase / IL-1b / TNF-a / Plasmodium falciparum-cultured supernatant / TNF-α抑制物質 / MAPKカスケード / lL-1β / 免疫抑制 / COX-2 / IL-1β / 熱帯熱マラリア培養上清 / マンソン裂頭条虫擬充尾虫 / iNOS / Chemokine / Cytokine / Tape worm / 融合蛋白 / cDNA / トリプシン・インヒビター / プロテアーゼ / TNF-α抑制因子 / 腹腔マクロファージ / ケモカイン / 条虫 / Host-parasite relationship / Cathepsin-L like substance / システインプロテイナーゼ / 宿主-寄生体関係 / 宿主一寄生体関係 / カテプシン-L様因子 / 凝充尾虫 / Growth hormone-like factor / cystein proteinase / Macrohage / Sprometra erinacei / 成長ホルモン結合蛋白 / システインプロテアーゼ / Plerocercoid Immunosuppressive Factor / 免疫抑制物質 / MAPK経路 / 破骨細胞 … More Except Principal Investigator TNF-α / chemokine / macrophage / マンソン裂頭条虫 / マクロファージ / gene expression / 遺伝子発現 / ケモカイン / LPS / IP-10 / NF-κB / nitric oxide synthase / 一酸化窒素合成酵素 / COX-2 / IL-1β / IFN-γ / Spirometra erinaceieuropaei / northern blot / parasite / インターフェロン-γ / 寄生虫 / immunosuppressive factor / IFN-β / ISRE / CXCL10 / マンソン裂頭条虫擬充尾虫 / IL-12 / ヘルパーT細胞1型 / 樹状細胞 / 免疫抑制因子 / 免疫抑制遺伝子 / secretory products / Excretory / MAPK / NF-кB / INF-γ / INF-α / MHC-II / NO / RAW 264.7 / Spriometra erinaceieuropaei / Northern blot / IL-1 / RAW264.7 / Spirometra erimaceieuropaei / マイソン裂頭条虫 / Northern Blot / サイトカイン / Spirometra erimacei / 遺伝子発現抑制 / Northern Blotting / 一酸化窒素合成酸素 / プレロセルコイド / TNFα / 擬充尾虫 / ノザンブロット / 研修会 / 授業 / 遺伝子 / 中等教育 / 組換えDNA実験 Less

Reasearch on the immunoregulatory factor from a parasite on the gene expression and the function of dendritic cells and macrophages
- Principal Investigator
  
  FUKUMOTO Soji
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Tottori University
マンソン裂頭条虫擬充尾虫が産生する生理活性物質についての研究Principal Investigator
- Principal Investigator
  
  平井和光
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Tottori University
高等学校における組換えDNA実習を通した遺伝子教育に関する研究
- Principal Investigator
  
  田中伸和
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Humanities and Social Sciences
- Research Institution
  Hiroshima University
Research on a parasite factor suppressing the gene expression of TNF-α and chemokines in macrophages
- Principal Investigator
  
  FUKUMOTO Soji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Tottori University
Studies on the bioactive substances produced by plerocercoids of Spirometra erinaceieuropaeiPrincipal Investigator
- Principal Investigator
  
  HIRAI Kazumitsu
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Tottori University
Studies on the suppressive factor from parasite of NO synthase and cytokine gene expression in macrophages
- Principal Investigator
  
  FUKUMOTO Soji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  TOTTORI UNIVERSITY
Studies on physiologically active substances produced by plerocercoids of Spirometra erinaceieuropaei.Principal Investigator
- Principal Investigator
  
  HIRAI Kazumitsu
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Tottori University
Effects of parasites on the gene expression of nitric oxide synthase and cytokine in macrophages
- Principal Investigator
  
  FUKUMOTO Soji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  TOTTORI University
Studies on the growth hormone-like substance produced by plerocercoid of Spirometra erinaceieuropaei.Principal Investigator
- Principal Investigator
  
  HIRAI Kazumitsu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  TOTTORI UNIVERSITY
Effects of parasites on the gene expression of nitric oxide synthase and chemokine in macrophages
- Principal Investigator
  
  FUKUMOTO Soji
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  TOTTORI UNIVERSITY
Studies on the growth hormone-like substance produced by plerocercoid of Spirometra erinacei.Principal Investigator
- Principal Investigator
  
  HIRAI Kazumitsu
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学）
- Research Institution
  Tottori University
Studies on the Growth Hormone-Like Factor Produced by Plerocercoids of Spirometra erinacei.Principal Investigator
- Principal Investigator
  
  HIRAI Kazumitsu
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学）
- Research Institution
  Ehime University
Studies on Growth-Promoting Factor Induced by Plerocercoids of Spirometra erinacei.Principal Investigator
- Principal Investigator
  
  HIRAI Kazumitsu
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学）
- Research Institution
  Ehime University

All 2006 2005 2004 2003

All Journal Article Book

[Book] Progress of Medical Parasitology in Japan: 3.Spirometra erinaceieuropaei (2)Growth hormone-like Factor produced by Plerocercoids of Spirometra erinaceieuropaei2003
- Author(s)
  Kazumitsu Hirai
- Total Pages
  684
- Publisher
  Meguro Parasitological Museum
- Data Source
  KAKENHI-PROJECT-15590368
[Journal Article] Suppression of LPS-induced cyclooxygenase-2 (cox-2) gene expression in mouse macrophages by the excretory/secretory products of Spirometra erinaceieuropaei plerocercoids.2006
- Author(s)
  S.Fukumoto, P.Dirgahayu, K.Nunomura, H.Matsuura, K.Hirai
- Journal Title
  
  Yonago Acta medica 49(1)
  
  Pages: 39-47
- NAID
  110004600419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590339
[Journal Article] Suppression of LPS-induced cyclooxygenase-2 (cox-2) gene expression in mouse macrophages by the excretory/secretory products of Spirometra erinaceieuropaei plerocercoids.2006
- Author(s)
  Fukumoto S, Dirgahayu P, Nunomura K, Matsuura H, Hirai K
- Journal Title
  
  Yonago Acta medica 49・1
  
  Pages: 39-47
- NAID
  110004600419
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590339
[Journal Article] A glycoprotein from Spirometra erinaceieuropaei plerocercoids suppress osteoclastgenesis and proinflammtory cytokine gene expression2005
- Author(s)
  Y.Kina, S.Fukumoto, K.Miura, S.Tademoto, K.Nunomura, P.Dirgahayu, K.Hirai
- Journal Title
  
  International Journal for Parasitology 35(13)
  
  Pages: 1399-1406
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590339
[Journal Article] A glycoprotein from Spirometra erinaceieuropaei plerocercoids suppress osteoclastgenesis and proinflammtory cytokine gene expression2005
- Author(s)
  Y.kina, S.Fukumoto, K.Miura, S.Tademoto, K.Nunomura, P.Dirgahayu, K.Hirai
- Journal Title
  
  International Journal for Parasitology 35・13
  
  Pages: 1399-1406
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590339
[Journal Article] Excretory/secretory products from plerocercoids of Spirometra erinaceieuropaei suppress interleukin-lb gene expression in murine macrophages.2004
- Author(s)
  P.Dirgahayu, S.Fukumoto, S.Tademoto, Y.Kina, K.Hirai
- Journal Title
  
  International Journal for Parasitology 34・5
  
  Pages: 577-584
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590339
[Journal Article] Excretory/secretory products from plerocercoids of Spirometra erinaceieuropaei suppress interleukin-1β gene expression in murine macrophages2004
- Author(s)
  P.Dirgahayu, S.Fukumoto, S.Tademoto, Y.Kina, K.Hirai
- Journal Title
  
  International Journal for Parasitology 34(5)
  
  Pages: 577-584
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590339

1. FUKUMOTO Sohji (60111126)

# of Collaborated Projects: 10 results

# of Collaborated Products: 6 results
2. SATO Kenzou (40113196)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TSUBOI Takafumi (00188616)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. WANG Haoran (80314574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 田中伸和 (50263744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 白石友紀 (10033268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 松田英幸 (50032595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 河野道生 (40161343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 豊島良太 (50144671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 谷畑健生 (00283979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 三浦憲豊 (10335507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

HIRAI Kazumitsu 平井 和光

Research Projects

Research Products

Co-Researchers

Reasearch on the immunoregulatory factor from a parasite on the gene expression and the function of dendritic cells and macrophages

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マンソン裂頭条虫擬充尾虫が産生する生理活性物質についての研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

高等学校における組換えDNA実習を通した遺伝子教育に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on a parasite factor suppressing the gene expression of TNF-α and chemokines in macrophages

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the bioactive substances produced by plerocercoids of Spirometra erinaceieuropaeiPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the suppressive factor from parasite of NO synthase and cytokine gene expression in macrophages

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on physiologically active substances produced by plerocercoids of Spirometra erinaceieuropaei.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of parasites on the gene expression of nitric oxide synthase and cytokine in macrophages

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the growth hormone-like substance produced by plerocercoid of Spirometra erinaceieuropaei.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of parasites on the gene expression of nitric oxide synthase and chemokine in macrophages

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the growth hormone-like substance produced by plerocercoid of Spirometra erinacei.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the Growth Hormone-Like Factor Produced by Plerocercoids of Spirometra erinacei.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on Growth-Promoting Factor Induced by Plerocercoids of Spirometra erinacei.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

HIRAI Kazumitsu 平井和光