KAWAGUCHI Mitsuru 川口充

… Alternative Names

川口充カワグチミツル

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Researcher Number	20096473
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2002 – 2006: 東京歯科大学, 歯学部, 教授 1996 – 2000: TOKYO DENTAL COLLEGE,DEP'T OF DENTISTRY,PROFESSOR, 歯学部, 教授 1995: 東京歯科大学, 薬理学講座, 教授 1992: 東京歯科大学, 薬理学講座, 教授
Review Section/Research Field	Principal Investigator Functional basic dentistry / Functional basic dentistry Except Principal Investigator Functional basic dentistry / 病態科学系歯学(含放射線系歯学) / 補綴理工系歯学
Keywords	Principal Investigator rat / 唾液腺 / 超音波導入法 / in vivo / siRNA / 2Cl^-共役輸送 / K^+ / Na^+ / Ca^<2+>依存性K^+チャネル / Cl^-チャネル … More / 末梢型受容体 / 中枢型受容体 / クロナゼパム / ジアゼパム / ベンゾジアゼピン … More Except Principal Investigator ベンゾジアゼピン受容体 / ホスホリパーゼC / 唾液分泌 / 唾液腺 / クロライドイオン / Phospholipase C / 向精神薬 / GTP結合蛋白質 / イノシトールリン脂質代謝 / ベンゾジアゼピン系薬物 / ascorbic acid / hydroxyl radical / Enamel / Dentin / metal ion / Hydroxyl radical / Super oxide / Hydrogen peroxide / Breaching / Vital tooth / 過酸化物の光分解 / 歯髄腔・根管 / ルミノール / ヒト抜去歯 / 光照射器(長波長紫外線・可視光線) / 過酸化尿素 / ヒドロペルオキシラジカル / ヒドロキシルラジカル / Fenton反応、Fenton様反応 / EPMA(XMA)X線マイクロアナライザー / 遷移金属 / 過酸化水素の光分解 / 歯の漂白剤 / 過酸化物 / 象牙質 / 可視光線 / 金属イオン / ヒドロキシラジカル / 活性酸素 / 過酸化水素 / 漂白 / 生活歯 / GTP-binding regulatory protein / phospholipase C / diazepam / intracellular signaling / phosphoinositide turnover / salivary gland / salivary secretion / アドレナリン受容体 / ムルカリン受容体 / 細胞内カルシウム / 耳下腺腺房細胞 / ジアゼパム / 細胞内情報伝達系 / イノシトールリン脂質代謝系 / Intracellular pH / Calcium ion / Chloride ion / Benzodiazepine receptor / Benzodiazepine / Salivary gland / Salivary secretion / G・蛋白質 / ベンゾジアゼピン類 / カルシウム / 細胞内pH / カルシウムイオン / ベンゾジアゼピン / GTP-Binding Regulatory Protein / Benzodiazepine Receptor / Phosphoinositide Metabolism / Salivary Secretion / Intracellular Signaling Mechanism / Salivary Gland / Benzodiazepines / イノシトール-3リン酸 / 口腔乾燥 / CTP結合蛋白質 / 細胞内情報伝達 / aldehydes / free radical scavenging / active oxygen species / Fenton reaction / dental drugs / phenolic compounds / super oxide / Fenton Haber-Weiss 反応 / 活性酸素消去能 / Fenton反応 / formaladehyde / ascozbic acid / TBA法 / 活性酸素消去作用 / Fenton,Harber-Wgiss反応 / formaldehyde / guaiacol / phenol類 Less

個体レベルの唾液腺機能解析の為のsiRNAと超音波を応用した遺伝子抑制法の開発Principal Investigator
- Principal Investigator
  
  川口充
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Dental College
Study of the suppression of salivary secretion induced by drugs : Effect of benzodiazepine drugs on the intracellular signaling in the salivary glands.
- Principal Investigator
  
  SAWAKI Kohei
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Tokyo Dental College
Bleaching of a tooth is caused by oxygen radical-Mechnism of bleaching of a tooth and influence to dentin of super oxygen-
- Principal Investigator
  
  KAWADA Eiji, 矢崎欽也
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Tokyo Dental College
CELLULAR STUDY OF INHIBITORY EFFECT OF BENZODIAZEPINES ON SALIVARY SECRETION
- Principal Investigator
  
  SAWAKI Kohei
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  TOKYO DENTAL COLLEGE
Functional study of phosphoinositide metabolism on the inhibitory mechanism of salivary secretion by psychotropic drug
- Principal Investigator
  
  SAWAKI Kohei
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  TOKYO DENTAL COLLEGE
The Correlation between free radical-scavenging effects and anti-inflammatory effects of dental drugs
- Principal Investigator
  
  YAZAKI Kinya
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  TOKYO DENTAL COLLEGE
薬物性口腔乾燥症の成立機序と機能回復についての薬理学的解析Principal Investigator
- Principal Investigator
  
  川口充
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Dental College

All 2007 2006 2002

All Journal Article

[Journal Article] Effects of MK-801 on the expression of serine racemase and d-amino acid oxidase mRNAs and on the D-serine levels in rat brain.2007
- Author(s)
  Hashimoto A, Yoshikawa M, Andoh H, Yano H, Matsumoto H, Kawaguchi M, Oka T, Kobayashi H
- Journal Title
  
  Eur J Pharmacol. 555・1
  
  Pages: 17-22
- Data Source
  KAKENHI-PROJECT-17659589
[Journal Article] Expression of the mRNA and protein of serine racemase in primary cultures of rat neurons.2006
- Author(s)
  Yoshikawa M, Nakajima K, Takayasu N, Noda S, Sato Y, Kawaguchi M, Oka T, Kobayashi H, Hashimoto A
- Journal Title
  
  Eur J Pharmacol. 548・1-3
  
  Pages: 74-76
- Data Source
  KAKENHI-PROJECT-17659589
[Journal Article] 実験技術耳下腺腺房細胞の調製法2006
- Author(s)
  大久保みぎわ, 川口充
- Journal Title
  
  日本薬理学雑誌 128・4
  
  Pages: 239-243
- Data Source
  KAKENHI-PROJECT-17659589
[Journal Article] 【唾液腺の機能と機能不全】唾液腺と糖尿病ストレス2006
- Author(s)
  渡辺正人, 川口充, 石川康子
- Journal Title
  
  日本薬理学雑誌 127・4
  
  Pages: 273-277
- Data Source
  KAKENHI-PROJECT-17659589
[Journal Article] Ketamine enhances the expression of serine racemase and D-amino acid oxidase mRNAs in rat brain.2006
- Author(s)
  Takeyama K, Yoshikawa M, Oka T, Kawaguchi M, Suzuki T, Hashimoto A
- Journal Title
  
  Eur J Pharmacol. 540・1-3
  
  Pages: 82-86
- Data Source
  KAKENHI-PROJECT-17659589
[Journal Article] 【楽の副作用】副作用の薬理薬物治療と口腔内障害2006
- Author(s)
  川口充, 澤木康平, 大久保みぎわ, 坂井隆之, 四宮敬史, 小菅康弘
- Journal Title
  
  日本薬理学雑誌 127・6
  
  Pages: 447-453
- Data Source
  KAKENHI-PROJECT-17659589
[Journal Article] Inhibitory effect of diazepam on muscarinic receptor-stimulated inositol 1,4,5-trisphosphate production in rat parotid acinar cells.2002
- Author(s)
  Masao Kujirai, Kohei Sawaki, Mitsuru Kawaguchi
- Journal Title
  
  British Journal of Pharmacology 137
  
  Pages: 945-952
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571800

1. YAZAKI Kinya (70157973)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. SAWAKI Kohei (50178828)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. OKUBO Migiwa (40301519)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. KAWADA Eiji (40147260)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. WATANABE Hiroki (00158651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 坂井隆之 (60260577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

KAWAGUCHI Mitsuru 川口 充

川口 充 カワグチ ミツル

Research Projects

Research Products

Co-Researchers

個体レベルの唾液腺機能解析の為のsiRNAと超音波を応用した遺伝子抑制法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of the suppression of salivary secretion induced by drugs : Effect of benzodiazepine drugs on the intracellular signaling in the salivary glands.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bleaching of a tooth is caused by oxygen radical-Mechnism of bleaching of a tooth and influence to dentin of super oxygen-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CELLULAR STUDY OF INHIBITORY EFFECT OF BENZODIAZEPINES ON SALIVARY SECRETION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional study of phosphoinositide metabolism on the inhibitory mechanism of salivary secretion by psychotropic drug

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Correlation between free radical-scavenging effects and anti-inflammatory effects of dental drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

薬物性口腔乾燥症の成立機序と機能回復についての薬理学的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effects of MK-801 on the expression of serine racemase and d-amino acid oxidase mRNAs and on the D-serine levels in rat brain.2007

Author(s)

Journal Title

Data Source

[Journal Article] Expression of the mRNA and protein of serine racemase in primary cultures of rat neurons.2006

Author(s)

Journal Title

Data Source

[Journal Article] 実験技術 耳下腺腺房細胞の調製法2006

Author(s)

Journal Title

Data Source

[Journal Article] 【唾液腺の機能と機能不全】唾液腺と糖尿病ストレス2006

Author(s)

Journal Title

Data Source

[Journal Article] Ketamine enhances the expression of serine racemase and D-amino acid oxidase mRNAs in rat brain.2006

Author(s)

Journal Title

Data Source

[Journal Article] 【楽の副作用】副作用の薬理 薬物治療と口腔内障害2006

Author(s)

Journal Title

Data Source

[Journal Article] Inhibitory effect of diazepam on muscarinic receptor-stimulated inositol 1,4,5-trisphosphate production in rat parotid acinar cells.2002

Author(s)

Journal Title

Description

Data Source

KAWAGUCHI Mitsuru 川口充

川口充カワグチミツル

[Journal Article] 実験技術耳下腺腺房細胞の調製法2006

[Journal Article] 【楽の副作用】副作用の薬理薬物治療と口腔内障害2006