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SHIONO Hiroshi  塩野 寛

ORCIDConnect your ORCID iD *help
Researcher Number 20112451
Other IDs
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Affiliation (based on the past Project Information) *help 2004 – 2005: 旭川医科大学, 医学部, 副学長
1997 – 2003: 旭川医科大学, 医学部, 教授
1992 – 1995: 旭川医科大学, 医学部, 教授
1991 – 1992: 島根医科大学, 医学部, 教授
1988 – 1989: Shimane Medical University, 医学部, 教授
Review Section/Research Field
Principal Investigator
Legal medicine / Legal medicine
Except Principal Investigator
Legal medicine
Keywords
Principal Investigator
性染色体 / マイクロサテライト / sex chromosome / microsatellite / allele distribution / Paternity testing / DNA polymorphisms / VNTR makers / Polymerase Chain Reaction / Personal identification … More / Sex determination / ABO blood group / Polymerase chain reaction / finger print / blood stain / Polymorphism / Sexchromosome / アリル分布 / 性犯罪 / sex crime / アリル分析 / 突然変異率 / mutation rate / 凍死 / オキシヘモグロビン比率 / 第一度凍傷(紅斑) / Wischnewdki斑 / 矛盾脱衣 / 左右心房血の色調差 / Wischnewski斑 / 左右心房血の色調査 / アルコール / 薬物 / Hypothermia / Oxyhemoglobin / First degree frostbite / Wischnewski's spots / Paradoxical undressing / Differences in color between right and left heart blood / パラコート / 肺障害 / 酸化的ストレス / ACE阻害作用 / 一酸化窒素 / アポトーシス / 腎障害 / ドパミン系 / 抗酸化作用 / paraquat / lung damage / oxidative stress / ACE inhibitor / NO / apoptosis … More
Except Principal Investigator
ECD / β-カルボリン / パーキンソン氏病 / 神経毒性 / N-メチル化酵素 / 人脳 / 環境毒 / 農薬 / パラコート / 神経変性疾患 / 神経興奮毒性 / パーキンソン病 / 線条体 / 遠隔授業 / 法医学 / コンピュータ / ネットワーク / 情報処理 / 単位互換 / 自己学習 / DNA分析 / 性別判定 / ポリメレース連鎖反応(PCR) / 性染色体 / アメロゲニン遺伝子 / ヘモグロビン / ヘマチン / ポリメレース・チェイン・リアクション(PCR)法 / DNA分解 / ポリメレ-ス・チェイン・リアクション(PCR)法 / DYZ1 / 縦列型反復配列遺伝子 / 単一コピ-遺伝子 / DNA analysis / Sex determination / Polymerase chain reaction / Sex chromosomes / Amelogenin gene / Degradation of DNA / Hemoglobin / Hematin / 自殺 / 脳内アミン / 遺伝子頻度 / DNA型 / セロトニンレセプター / トリプトファンハイドロキシレース / セロトニントランスポーター / Suicide / Neurotransmitter / Allele Frequency / DNA Type / Serotonin Receptor 1A Gene / Tryptophan Hydroxylase Gene / 大麻 / Δ^9ーテトラヒドロカンナビノール / キャピラリーカラムー電子捕獲型検出器付ガスクロマトグラフ / △^9-テトラヒドロカンナビノール / キャピラリーカラム-電子補獲型検出器付ガスクロマトグラフ / マリファナ喫煙 / キャピラリーGC / ダ液 / Toxicology / Marihuana smoking / ^9-Tetrahydrocannabinol / Capillary GC / Saliva Less
  • Research Projects

    (13 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (20 People)
  •  Study on the toxicological mechanism of paraquat-induced pulmonary fibrosis and its tentative therapeuticsPrincipal Investigator

    • Principal Investigator
      SHIONO Hiroshi, 清水 惠子
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Asahikawa Medical College
  •  パラコート中毒における中枢毒性発現機序に関する研究

    • Principal Investigator
      SHIMIZU Keiko (清水 恵子)
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Asahikawa Medical College
  •  法医学授業の他大学との連携・単位互換性の検討

    • Principal Investigator
      YOSHIOKA Naofumi
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Akita University
  •  The Establishment of diagnosis and the forensic pathological study on death in the cold.Principal Investigator

    • Principal Investigator
      SHIONO Hiroshi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Asahikawa Medical College
  •  Association study between the polymorphisms of neurotransmitter-related genes and suicide behavior.

    • Principal Investigator
      YOSHIOKA Naofumi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Legal medicine
    • Research Institution
      Akita University
  •  Polymorphism of Microsatellite Markers on Human Sex Chromosomes and analysis of mutation rate in the same individual.Principal Investigator

    • Principal Investigator
      SHIONO Hiroshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Asahikawa Medical College
  •  Polymorphism and Genetic Instability of Microsatellite Markers on Human Sex Chromosomes.Principal Investigator

    • Principal Investigator
      SHIONO Hiroshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Asahikawa Medical College
  •  性染色体上マーカーの分子生物学的解析と法医学試料への応用Principal Investigator

    • Principal Investigator
      塩野 寛
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Asahikawa Medical College
  •  分子生物学的手法を用いた性染色体DNA多型の法医学試料への応Principal Investigator

    • Principal Investigator
      塩野 寛
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Asahikawa Medical College
  •  β-カルボリンの脳内での活性化による神経毒の生成機序と肝における解毒化活性

    • Principal Investigator
      松原 和夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Shimane Medical University
  •  Investigation on dual PCR technique and its application to sex determination of forensic specimensPrincipal Investigator

    • Principal Investigator
      MATSUBARA Kazuo, 塩野 寛
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Shimane Medical University
  •  DNA解析の法医遺伝学的応用Principal Investigator

    • Principal Investigator
      塩野 寛
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Shimane Medical University
  •  Study of the proof for marihuana smoking by gas chromatographic analysis

    • Principal Investigator
      TAKAHASHI Setsunori
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Shimane Medical University

All 2006 2004 2003

All Journal Article

  • [Journal Article] Tandospirone, a 5-HT1A agonist, ameliorates movement disorder via non-dopaminergic systems in rats with unilateral 6-hydroxydopamine-generated lesions.2006

    • Author(s)
      K.Matsubara, K Shimizu, M Suno, K.Ogawa, T.Awaya, T.Yamada, T.Noda, M.Satomi, K.Ohtaki, K.Chiba, Y.Tasaki, H.Shiono
    • Journal Title

      Brain Research (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590571
  • [Journal Article] Tandospirone, a 5-HT1A agonist, ameliorates movement disorder via non-dopaminergic systems in rats with unilateral 6-hydroxydopamine-generated lesions.2006

    • Author(s)
      K.Matsubara, K.Shimizu, M.Suno, K.Ogawa, T.Awaya, T.Yamada, T.Noda, M.Satomi, K.Ohtaki, K.Chiba, Y.Tasaki, H.Shiono
    • Journal Title

      Brain Research, (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590571
  • [Journal Article] 急性パラコート中毒による末梢毒性機構の解明とその阻止薬の探索2004

    • Author(s)
      清水 恵子, 塩野 寛他
    • Journal Title

      日本法医学雑誌 58・1

      Pages: 77-77

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590571
  • [Journal Article] 急性パラコート中毒による末梢毒性機構の解明とその阻止薬の探索2004

    • Author(s)
      清水恵子, 塩野寛他
    • Journal Title

      日本法医学雑誌 58・1

      Pages: 77-77

    • Data Source
      KAKENHI-PROJECT-15590571
  • [Journal Article] Study on the mechanism of peripheral acute toxicity induced by paraquat and its tentative therapeutics.2004

    • Author(s)
      K Shimizu, M Asari, H Shiono, K Matsubara, K Ohotaki, T Awaya
    • Journal Title

      Japanese Journal of Legal Medicine 58

      Pages: 77-77

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590571
  • [Journal Article] Cefoselis, a beta-lactam antibiotic, easily penetrates the blood-brain barrier and causes seizure independently by glutamate release.2004

    • Author(s)
      K.Ohtaki, K.Matsubara, S.Fujimaru, K.Shimizu, T.Awaya, M.Suno, K.Chiba, N.Hayase, H.Shiono
    • Journal Title

      Journal of Neural Transmission 12

      Pages: 1523-1535

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590571
  • [Journal Article] Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture.2003

    • Author(s)
      K.Shimizu, K.Matsubara, K.Ohtaki, H.Shiono
    • Journal Title

      Brain Research 46

      Pages: 523-532

    • NAID

      10016207557

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590571
  • [Journal Article] Pralidoxime iodide (2-pAM) penetrates across the blood-brain barrier.2003

    • Author(s)
      K.Sakurada, K.Matsubara, K.Shimizu, H.Shiono, Y.Seto, K.Tsuge, M.Yoshino, I.Sakai, H.Mukoyama, T.Takatori
    • Journal Title

      Neurochemical Research 28

      Pages: 1401-1407

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590571
  • [Journal Article] Pralidoxime iodide(2-pAM)penetrates across the blood-brain barrier.2003

    • Author(s)
      K.Sakurada, K.Matsubara, K.Shimizu, H.Shiono, Y.Seto, K.Tsuge, M.Yoshino, I.Sakai, H.Mukoyama, T.Takatori
    • Journal Title

      Neurochemical Research 28:

      Pages: 1401-7

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590571
  • [Journal Article] Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture.2003

    • Author(s)
      K.Shimizu, K.Matsubara, K.Ohtaki, H.Shiono
    • Journal Title

      Brain Research 46:

      Pages: 523-32

    • NAID

      10016207557

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590571
  • [Journal Article] Paraquat induces long-lasting toxicity to striatal dopaminergic terminals through the excitotoxic pathway.2003

    • Author(s)
      K.Shimizu, K.Matsubara, K.Ohtaki, S.Fujimaru, O.Saito, H.Shiono
    • Journal Title

      Brain Research 976

      Pages: 243-52

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590571
  • 1.  MATSUBARA Kazuo (20127533)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 9 results
  • 2.  SHIMIZU Keiko (90312462)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 11 results
  • 3.  TAKAHASHI Setsunori (90032226)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  SASAKI Masahiro (80250546)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  AKANE Atsushi (70202520)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  YOSHIOKA Naofumi (80108935)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  UEZONO Takashi (70294387)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KIMURA Kojiro (30153191)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  FUKUSHIMA Tohru (30199210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ISHIZU Hideo (70033157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KATSUMATA Yoshinao (30109326)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  NAKASONO Ichirou (30108287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ASARI Masaru (40360979)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  AZUMI Jun-ichi (00045551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  池淵 淳 (30150361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  権守 邦夫 (10006744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  中村 彰 (20155815)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  福永 龍繁 (70156800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  福島 弘文 (70135218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  浜 久美子 (50167590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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