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KAWASE Masami  河瀬 雅美

ORCIDConnect your ORCID iD *help
Researcher Number 20112641
Other IDs
Affiliation (based on the past Project Information) *help 2007 – 2010: 松山大学, 薬学部, 教授
2002 – 2004: 城西大学, 薬学部, 講師
Review Section/Research Field
Principal Investigator
Drug development chemistry
Except Principal Investigator
病態科学系歯学(含放射線系歯学) / Functional basic dentistry
Keywords
Principal Investigator
口腔癌 / N-アシルプロリン / ジフルオロクロロメチルケ / 細胞毒性 / テトラハイドロイソキノリ / 活性型カルボニル / N-チオアシルプロリン / Dakin-West反応 / 構造活性相関 / 抗菌活性 … More / ジフルオロメチルケトン / クロロジフルオロメチルケト / ピロール / トリフルオロメチル / クオラムセンシング / オートファジー / アポトーシス / ヒドロキシケトン / クロロジフルオロメチルケトン / トリフルオロメチルケトン / カルボニル化合物 / 化合物ライブラリー … More
Except Principal Investigator
NO / アポトーシス / Drug resistance / Asparagine synthetase / Macrophage / Apoptosis / Oral carcinoma / Lignin / Polyphenol / 薬物代謝酵素 / アスパラギン / 薬剤耐性 / アスパラギン合成酵素 / マクロファージ / 口腔癌 / リグニン / ポリフェノール / プレニルアルコール / ビタミンK_2 / ベンズアルデヒド誘導体 / 細胞のタイプ / 環状α,β-不飽和ケトン / 細胞間での感受性の差 / β不飽和ケトン / 環状α / 構造活性相関 / オートファジー / 細胞死のタイプ / 口腔扁平上皮癌細胞 Less
  • Research Projects

    (3 results)
  • Research Products

    (70 results)
  • Co-Researchers

    (7 People)
  •  Small molecular library of alpha-fluorinated and -hydroxylated carbonyl compounds synthesized by newly developed reactionsPrincipal Investigator

    • Principal Investigator
      KAWASE Masami
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Matsuyama University
  •  Basic research for the development of autophagy-inducing therapy against human oral squamous cell carcinoma cell lines

    • Principal Investigator
      SAKAGAMI Hiroshi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Meikai University
  •  Study of clinical implication and application of polyphenols in the dentistry

    • Principal Investigator
      SAKAGAMI Hiroshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Meikai University School of Dentistry

All 2010 2009 2008 2007 2005 2004 Other

All Journal Article Presentation Book

  • [Book] Top Heterocycl Chem 16(ed., Noboru Motohash, The chemistry of bioactive mesoionic heterocycles)2009

    • Author(s)
      Kawase M, Sakagami H, Motohashi N
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Book] Top Heterocycl Chem 16(ed., Noboru Motohash, Quantitative Structure-Cytotoxicity Relationship of bioactive heterocycles by semi-empirical molecular orbital method with concept of absolute hardness)2009

    • Author(s)
      Ishihara M, Sakagami H, Kawase M, Motohashi N
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Book] Quantitative Structure-Cytotoxicity Relationship of bioactive heterocycles by semi-empirical molecular orbital method with concept of absolute hardness.Top Heterocycl Chem Vol 16 pp 93-133,(ed., Noboru Motohashi)2009

    • Author(s)
      Ishihara M, Sakagami H, Kawase M, Motohashi N
    • Total Pages
      41
    • Publisher
      Springer-Verlag Berlin Heiderberg
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Book] Functional Polyphenols with Antioxidative Action, a review book series of "Chem. Pharmaceutical Sciences (CPS),ed.,Motohashi"("REFLASH", India) (ed)2005

    • Author(s)
      Kawase M, Motohashi N, Sakagami H
    • Publisher
      (In press)
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Book] Structure-cytotoxicity relationship of selected dietary phenols and the related compounds in tumor cells2005

    • Author(s)
      Kawase M, Motohashi N, Sakagami H
    • Publisher
      Functional Polyphenols with Antioxidative Action REFLASH, India(In press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Sequential Cytotoxicity : A Theory Examined Using a Series of 3,5-Bis(benzylidene)-1-diethylphosphono-4-oxopiperidines and Related Phosphonic Acids.2010

    • Author(s)
      S.Das, U.Das, H.Sakagami, K.Hashimoto, M.Kawase, D.K.J.Gorecki, J.R.Dimmock
    • Journal Title

      Bioorg.Med.Chem.Lett. 20

      Pages: 6464-6468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] 3,5-Bis(benzylidene)-1-[4-2(morpholin-4-yl)ethoxyphenylcarbonyl]-4-piperidone hydrochloride : a lead tumor-specific cytotoxin which induces apoptosis and autophagy2010

    • Author(s)
      U.Das, H.Sakagami, Q.Chu, Q.Wang, M.Kawase, 他3名
    • Journal Title

      Bioorg.Med.Chem.Lett. 20

      Pages: 912-917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] 3,5-Bis(benzylidene)-1-[4-2-(morpholin-4-yl)ethoxyphenylcarbonyl]-4-piperidone Hydrochloride : A Lead Tumor-specific Cytotoxin Which Induces Apoptosis and Autophagy.2010

    • Author(s)
      U.Das, H.Sakagami, Q.Chu, Q.Wang, M.Kawase, P.Selvakumar, R.K.Sharma, J.R.Dimmock
    • Journal Title

      Bioorg.Med.Chem.Lett. 20

      Pages: 912-917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] Cytotoxic 2-Benzylidene-6-(nitrobenzylidene)cyclo hexanones Which Demonstrate Substantially Greater Toxicity for Neoplasms than Non-malignant Cells.2010

    • Author(s)
      U.Das, A.Doroudi, H.I.Gul, H.N.Pati, M.Kawase, H.Sakagami, Q.Chu, J.P.Stables, J.R.Dimmock
    • Journal Title

      Bioorg.Med.Chem. 18

      Pages: 2219-2224

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] New Synthesis of 3-Trifluoromethylpyrroles by Condensation of Mesoionic 4-Trifluoroacetyl-1,3-oxazolium-5-olates with Phosphorus-ylides.2010

    • Author(s)
      R.Saijo, Y.Hagimoto, M.Kawase
    • Journal Title

      Org.Lett.

      Volume: 14 Pages: 4776-4779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] Sequential Cytotoxicity : A Theory Examined Using a Series of 3,5-Bis(benzylidene)-1-diethylphosphono-4-oxopiperidines and Related Phosphonic Acids.2010

    • Author(s)
      S.Das, U.Das, H.Sakagami, K.Hashimoto, M.Kawase, 他3名
    • Journal Title

      Bioorg.Med.Chem.Lett.

      Volume: 20 Pages: 6464-6468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] 3, 5-bis(Benzylidene)-1-[4-2-(morpholin-4-yl)ethoxyphenylcarbonyl]-4-pi peridone hydrochloride: A lead tumour-specific cytotoxin which induces apoptosis and autophagy.2010

    • Author(s)
      Das U, Sakagami H, Chu Q, Wang Q, Kawase M, Selvakumar P, Sharma RK, Dimmock JR
    • Journal Title

      Medicinal Chemistry Letters 20

      Pages: 912-917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Cytotoxic 2-benzylidene-6-(nitrobenzylidene)cyclohex anones which display substantially greater toxicity for neoplasms than non-malignant cells.2010

    • Author(s)
      Das U, Doroudi A, Gul HI, Pati HN, Kawase M, Sakagami H, Chu Q, Stables JP, Dimmock JR
    • Journal Title

      Bioorg Med Chem 18

      Pages: 2219-2224

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] 1,3-Diaryl-2-propenones and 2-Benzylidene-1,3-indandiones : A Quest for Compounds Displaying Greater Toxicity to Neoplasms than Normal Cells.2010

    • Author(s)
      H.N.Pati, U.Das, H.Sakagami, M.Kawase, Q.Chu, Q.Wang, J.P.Stables, J.R.Dimmock
    • Journal Title

      Archiv der Pharmazie 9

      Pages: 535-541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] New Synthesis of 3-Trifluoromethylpyrroles by Condensation of Mesoionic 4-Trifluoroacetyl-1,3-oxazolium-5-olates with Phosphorus-ylides.2010

    • Author(s)
      R.Saijo, Y.Hagimoto, M.Kawase
    • Journal Title

      Org.Lett. 14

      Pages: 4776-4779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] 1,3-Diaryl-2-propenones and 2-Benzylidene-1,3-indandiones : A Quest for Compounds Displaying Greater Toxicity to Neoplasms than Normal Cells.2010

    • Author(s)
      H.N.Pati, U.Das, H.Sakagami, M.Kawase, 他4名
    • Journal Title

      Archiv der Pharmazie

      Volume: 9 Pages: 535-541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] Estimation of relationship between the structure of 1,2,3,4-tetrahydroisoquinolin derivatives determined by asemiempirical molecular-orbital method and their cytotoxicity2009

    • Author(s)
      Ishihara M, Hatano H, Kawase M, Sakagami H
    • Journal Title

      Anticancer Research 29

      Pages: 2265-2272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] 2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1, 4-dioxides: A novel cluster of tumor-specific cytotoxins which reverse multidrug resistance.2009

    • Author(s)
      Das U, Pati HN, Panda AK, De Clercq E, Balzarini J, Molnar J, Barath Z, Ocsovszki I, Kawase M, Zhou L, Sakagami H, Dimmock JR
    • Journal Title

      Bioorg Med Chem 17

      Pages: 3909-3915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Estimation of relationship between descriptors and cytotoxicity of newly synthesized 1, 2, 3, 4-tetrahydroisoquinoline derivatives.2009

    • Author(s)
      Ishihara M, Hatano H, Takekawa F, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 29

      Pages: 4077-4082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Type of cell death induced byα-trifluoromethyl acyloins in oral squamous cell carcinoma.2009

    • Author(s)
      Ideo A, Hashimoto K, Shimada J, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 29

      Pages: 175-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] 2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides : A Novel Cluster of Tumor-specific Cytotoxins which Reverse Multidrug Resistance.2009

    • Author(s)
      U.Das, H.N.Pati, A.K.Panda, E.De Clercq, J.Balzarini, J.Molnar, Z.Barath, I.Ocsovzki, M.Kawase, H.Sakagami, J.R.Dimmock
    • Journal Title

      Bioorg.Med.Chem. 17

      Pages: 3909-3915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] The cytotoxic properties and preferential toxicity to tumour cells displayed by some 2, 4-bis(benzylidene)-8-methyl-8-azabicyclo[ 3. 2. 1]octan-3-ones and 3, 5-bis(benzylidene)-1-methyl-4-piperidones.2009

    • Author(s)
      Pati HN, Das U, Bandy B, Das S, De Clercq E, Balzirini J, Kawase M, Sakagami H, Quail JW, Stables JP, Dimmock JR
    • Journal Title

      Eur J Med Chem 44

      Pages: 54-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specific Cytotoxic Activity of 1,2,3,4-Tetrahydroisoquinoline Derivatives against Human Oral Squamous Cell Carcinoma Cell Lines.2009

    • Author(s)
      H.Hatano, H.Takekawa, K.Hashimoto, M.Ishihara, M.Kawase, C.Qing, W.Qin-Tao, H.Sakagami
    • Journal Title

      Anticancer Res. 29

      Pages: 3079-3086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] The Dakin-West Reaction of N-Acylprolines in the Presence of Inorganic Bases : Unexpected Formation of Enol Esters.2009

    • Author(s)
      M.Saeki, Y.Hagimoto, H.Uno, M.Kawase
    • Journal Title

      Heterocycles 79

      Pages: 821-830

    • NAID

      40016543110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] Type of cell death induced by α-trifluoromethyl acyloins in oral squamous cell carcinoma.2009

    • Author(s)
      A. Ideo, K. Hashimoto, J. Shimada, M. Kawase, H. Sakagami
    • Journal Title

      Anticancer Res. 29

      Pages: 175-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] Type of Cell Death Induced by alpha-Trifluoromethyl Acyloins in Oral Squamous Cell Carcinoma.2009

    • Author(s)
      A.Ideo, K.Hashimoto, J.Shimada, M.Kawase, H.Sakagami
    • Journal Title

      Anticancer Res. 29

      Pages: 175-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] Estimation of relationship between the structure of 1, 2, 3, 4-tetrahydroisoquinolin derivatives determined by a semiempirical molecular-orbital method and their cytotoxicity.2009

    • Author(s)
      Ishihara M, Hatano H, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 29

      Pages: 2265-2272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] The Chemistry of Bioactive Mesoionic Heterocycles2009

    • Author(s)
      M. Kawase, H. Sakagami, N. Motohashi
    • Journal Title

      Topics in Heterocyclic Chemistry (Bioactive Heterocycles VII) 16

      Pages: 135-152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] The Chemistry of Bioactive Mesoionic Heterocycles.2009

    • Author(s)
      M.Kawase, H.Sakagami, N.Motohashi
    • Journal Title

      Top.Heterocycl.Chem.(Bioactive Heteroycles VII), Splinger-Verlag 16

      Pages: 135-152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] Tumor-specific cytotoxic activity of 1, 2, 3, 4-tetrahydroisoquinoline derivatives against human oral squamous cell carcinoma cell lines2009

    • Author(s)
      Hatano H, Takekawa H, Hashimoto K, Ishihara M, Kawase M, Chu Q, Wang QT, Sakagami H
    • Journal Title

      Anticancer Res 29

      Pages: 3079-3086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] The Dakin-West reaction of N-acylprolines in the presence of inorganic bases2009

    • Author(s)
      M. Saeki, Y. Hagimoto, H. Uno, M. Kawase
    • Journal Title

      Heterocycles 79

      Pages: 821-830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] Tumor-specific cyctotoxic activity of 1,2,3,4-tetrahydroisoquinoline derivatives against human oral squamous cell carcinoma cell line2009

    • Author(s)
      H.Hatano, F.Takekawa, K.Hashimoto, M.Ishihara, M.Kawase, 他3名
    • Journal Title

      Anticancer Res. 29

      Pages: 3079-3086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] 2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides : a novel cluster of tumor-specific cytotoxins which reverse multidrug resistance2009

    • Author(s)
      U.Das, H.N.Pati, A.K.Panda, E.D.Clercq, J.Balzarini, M.Kawase, 他6
    • Journal Title

      Bioorg.Med.Chem. 17

      Pages: 3909-3915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Journal Article] Cytotoxic 3, 5-bis(arylidene)-4-piperidones and N-acetylanalogs displaying selective toxicity for malignant cells.2008

    • Author(s)
      Pati HN, Das U, Quail JW, Kawase M, Sakagami H, Dimmock JR
    • Journal Title

      Eur J Med Chem 43

      Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Design, synthesis and antiproliferative activity of some 3-benzylidene-2, 3-dihydro-1-benzopyran-4-ones which display selective toxicity for malignant cells.2008

    • Author(s)
      Perjesi P, De Clercq E, Balzarini J, Kawase M, Sakagami H, Stables JP, Lorand T, Rozmer, Dimmock JR
    • Journal Title

      Eur J Med Chem 43

      Pages: 839-845

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] 1-Aryl-2-dimethylaminomethyl-2-propen-1-one hydrochlorides and related adducts: a quest for selective cytotoxicity for malignant cells.2008

    • Author(s)
      Pati HN, Das U, Kawase M, Sakagami H, Balzarini J, De Clercq E, Dimmock JR
    • Journal Title

      Bioorg Med Chem 16

      Pages: 5747-5753

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Quantitative structure-cytotoxicity relationship analysis of 5-trifluoromethyloxazole derivatives by semiempirical molecular-orbital method with concept of absolute hardness.2008

    • Author(s)
      Ishihara M, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 28

      Pages: 997-1004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] 3-(3, 4, 5-Trimethoxyphenyl)-1-oxo-2-propen e: A novel phamacophore displaying potent multidrug resistance reversal and selective cytotoxicity.2007

    • Author(s)
      Das U, Kawase M, Sakagami H, Ideo A, Shimada J, Molnar J, Molnar J, Barath Z, Bata Z, Dimmock JR
    • Journal Title

      Bioorg Med Chem 15

      Pages: 3373-3380

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specific cytotoxic activity and type of cell death induced by 4-trifluoromethylimidazoles in human oral squamous cell carcinoma cell lines.2007

    • Author(s)
      Takekawa F, Nagumo T, Shintani S, Hashimoto K, Kikuchi H, Katayama T, Ishihara M, Amano O, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 27

      Pages: 4065-4070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Factors that affect the type of cell death induced by chemicals.2007

    • Author(s)
      Sakagami H, Kawase M, Wakabayashi H, Kurihara T
    • Journal Title

      Autophagy 3

      Pages: 493-495

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Quantitative structure-activity relationship analysis of 4-trifluoromethylimidazole derivatives with the concept of absolute hardness.2007

    • Author(s)
      Ishihara M, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 27

      Pages: 4047-4052

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Tumor-specificity and type of cell death induced by phenoxazines.2007

    • Author(s)
      Suzuki F, Hashimoto K, Ishihara M, Westman G, Samuelsson K, Kawase M, Motohashi N, Sakagami H
    • Journal Title

      Anticancer Res 27

      Pages: 4233-4238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Quantitative Structure-cytotoxicity relationship analysis of phenoxazine derivatives by semiempirical molecular-orbital method.2007

    • Author(s)
      Ishihara M, Kawase M, Westman G, Samuelson K, Motohashi N, Sakagami H
    • Journal Title

      Anticancer Res 27

      Pages: 4053-4058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Journal Article] Bioactivities of Anastasia black of functional sweet pepper2005

    • Author(s)
      Shirataki Y, Kawase M, Sakagami H et al.
    • Journal Title

      Anticancer Res 25(In press)

    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Tumor-specific cytotoxic activity of polyphenols, terpenoids, ketones and other synthetic compounds2005

    • Author(s)
      Sakagami H, Chowdhury SA, Suzuki F, Hashimoto K, Hatano H, Takekawa H, Ishihara M, Kikuchi H, Nishikawa H, Tamguchi S, Ito H, Hatano T, Yoshida T, Fukai T, Shirataki Y, Kawase M, Watanabe K, Mimaki Y, Itoh K, Horiuchi A, Chai W, Horiuchi A, Motohashi N
    • Journal Title

      Functional Polyphenols with Antioxidative Action, a review book series of "Chem. Pharmaceutical Sciences (CPS), ed. (Motohashi"("REFLASH", India) (ed)) (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Tumor-specific cytotoxicity of 3,5-dibenzoyl-1,4-dihydropyridines2005

    • Author(s)
      Morshed SRM, Hashimoto K, Murotani Y, Kawase M, Shah A, Satoh K, Kikuchi H, Nishikawa H, Maki J, Sakagami H
    • Journal Title

      Anticancer Res 25(3) (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Induction of tumor-specific cytotoxicity and apoptosis by doxorubicin2005

    • Author(s)
      Suzuki F, Hashimoto K, Kikuchi H, Nishikawa H, Matsumoto H, Shimada J, Kawase M, Sunaga K, Tsuda T, Satoh K, Sakagami H
    • Journal Title

      Anticancer Res 25

      Pages: 887-894

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Structure-cytotoxicity relationship of selected dietary phenols and the related compounds in tumor cells2005

    • Author(s)
      Kawase M, Motohashi N, Sakagami H
    • Journal Title

      Functional Polyphenols with Antioxidative Action, a review book series of "Chem. Pharmaceutical Sciences (CPS), ed. (Motohashi"("REFLASH", India) (ed)) (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Bioactivities of Anastasia black of functional sweet pepper.2005

    • Author(s)
      Shirataki Y, Kawase M, Sakagami H et al.
    • Journal Title

      Anticancer Res 25(in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] 3-Arylidene-1-(4-nitrophenylmethylene)-3,4-dihydro- 1H-naphthalen-2-ones and related compounds displaying selective toxicity and reversal of multidrug resistance in neoplastic cells.2005

    • Author(s)
      Dimmock JR, Das U, Gul HI, Kawase M, Sakagami H et al.
    • Journal Title

      Bioorg Med Chem Lett (In press)

    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Antitumor potential of polyphenols : possible application to oral cancer therapy2005

    • Author(s)
      Sakagami H, Hatano H, Takekawa H, Satoh K, Kanno M, Kawase M, Motohashi N
    • Journal Title

      Functional Polyphenols with Antioxidative Action, a review book series of "Chem Pharmaceutical Sciences (CPS), ed. (Motohashi"("REFLASH", India) (ed)) (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] 3-Arylidene-1 -(4-nitrophenylmethylene)-3, 4-dihydro-1 H-naphthalen-2-ones and related compounds displaying selective toxicity and reversal of multidrug resistance in neoplastic cells2005

    • Author(s)
      Dimmock JR, Das U, Gul HI, Kawase M, Sakagami H, Barath Z, Ocsovsky I, Molnar J
    • Journal Title

      Bioorg Med Chem Lett 15(6)

      Pages: 1633-1636

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] 3-Arylidene-1-(4-nitrophenylmethylene)-3,4-dihydro-1H-naphthalen-2-ones and related compounds displaying selective toxicity and revesal of multidrug resistance in neoplastic cells.2005

    • Author(s)
      Dimmock JR, Das U, Gul HI, Kawase M et al.
    • Journal Title

      Bioorg Med Chem Lett 15(6)

      Pages: 1633-1636

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Bioactivities of Anastasia black of functional sweet pepper2005

    • Author(s)
      Shirataki Y, Kawase M, Sakagami H, Nakashima H, Tani S, Tanaka T, Sohara Y, Schelz Z, Molnar J, Motohashi N
    • Journal Title

      Anticancer Res 25 (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Biological activity of an Indian medical plant, Indigofera cordifolia.2004

    • Author(s)
      Rao BK, Kawase M, Tanaka T et al.
    • Journal Title

      Orient Pharm Exp Med 4

      Pages: 179-185

    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines2004

    • Author(s)
      Yasumoto E, Nakano K, Nakayachi T, Morshed SRM, Hashimoto K, Kikuchi H, Nishikawa H, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 24

      Pages: 755-762

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Relationship between electronic structure and cytotoxic activity of 3-benzazepine-related compounds2004

    • Author(s)
      Kurihara T, Yamada T, Yamamoto A, Kawase M, Motohashi N, Sakagami H, Molnar J
    • Journal Title

      Heterocyclic Chemistry. Edited by D.C.Gautam, RBSA Publishers

      Pages: 16-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Induction of apoptosis by β -diketones in human tumor cells2004

    • Author(s)
      Nakano K, Nakayachi T, Yasumoto E, Morshed SRM, Hashimoto K, Kikuchi H, Nishikawa H, Sugiyama K, Amano O, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 24

      Pages: 711-718

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Biological activity of an Indian medical plant, Indigofera cordifolia2004

    • Author(s)
      Rao BK, Kawase M, Tanaka T, Tani S, Motohashi N, Satoh K, Sakagami H, Terakubo S, Nakashima H, Wolfard K, Molnar J
    • Journal Title

      Orient Pharm Exp Med 4(3)

      Pages: 179-185

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Biological activity of an Indian medical plant, Indigofera cordifolia.2004

    • Author(s)
      Rao BK, Kawase M, Tanaka T, Tani S et al.
    • Journal Title

      Orient Pharm Exp Med 4(3)

      Pages: 179-185

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Structure-activity relationships of α, β -unsaturated ketones as assessed by their cytotoxicity against oral tumor cells2004

    • Author(s)
      Nakayachi T, Yasumoto E, Nakano K, Morshed SRM, Hashimoto K, Kikuchi H, Nishikawa H, Kawase M, Sakagami H
    • Journal Title

      Anticancer Res 24

      Pages: 737-742

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Functional activity of Barbados cherry (Acerola fruits, fruit of Malpighia emarginata DC.) extracts and fractions2004

    • Author(s)
      Motohashi N, Wakabayashi H, Kurihara T, Fukushima H, Yamada T, Kawase M, Sohara Y, Tani S, Shirataki Y, Sakagami H, Satoh K, Nakashima H, Molnar A, Spengler G, Gyemant N, Ugocsai K, Molnar J
    • Journal Title

      Phytother Res 18

      Pages: 212-223

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] Relationship between electric structure and cytotoxic activity on dopamine and 3-bezazepine derivatives2004

    • Author(s)
      Kurihara T, Yamada T, Yamamoto A, Kawase M, Motohashi N, Molnar J
    • Journal Title

      In vivo 18

      Pages: 443-448

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370607
  • [Journal Article] 1, 3-Diaryl-2-propenones and 2-benzylidene-1, 3-indandiones: A quest for compounds displaying greater toxicity to neoplasms than normal cells.

    • Author(s)
      Pati HN, Das U, Sakagami H, Kawase M, Chu Q, Wang Q, Stables JP, Dimmock JR
    • Journal Title

      Archiv der Pharmazie (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Presentation] N-チオアシル-α-アミノ酸の Dakin-West 反応を利用した5-トリフルオロメチルチアゾール類の合成2010

    • Author(s)
      萩本有理, 河瀬雅美
    • Organizer
      日本薬学会130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-28
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Presentation] メソイオンとイリドの反応:3-トリフルオロメチルピロール類の合成2010

    • Author(s)
      西條亮介,萩本有理,河瀬雅美
    • Organizer
      第36回反応と合成の進歩シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2010-11-01
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Presentation] メソイナンとイリドの反応:3-トリフルオロメチルピロール類の合成2010

    • Author(s)
      西條亮介, 萩本有理, 河瀬雅美
    • Organizer
      第36回反応と合成の進歩シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2010-11-01
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Presentation] N-チオアシル-alpha-アミノ酸のDakin-West反応を利用した5-トリフルオロメチルチアゾール類の合成2009

    • Author(s)
      萩本有理、河瀬雅美
    • Organizer
      日本薬学会130年会
    • Place of Presentation
      岡山
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-20590114
  • [Presentation] Induction of non-apoptosis by a, b-unsaturated ketones in OSCC cell lines2008

    • Author(s)
      Sakagami H, Hashimoto K, Ishihara M, Nagasaka H, Kawase M, Dimmock J
    • Organizer
      IADR
    • Place of Presentation
      Toronto
    • Data Source
      KAKENHI-PROJECT-19592156
  • [Presentation] 複素環式化合物の腫瘍選択性と誘導される細胞死のタイプ2008

    • Author(s)
      坂上宏, 橋本研, 小林正樹, 鈴木史香, 竹川文弘石原真理子, 天野修, 菊地寛高, 中村幸生, 河瀬雅美, 本橋登
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19592156
  • 1.  SAKAGAMI Hiroshi (50138484)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 56 results
  • 2.  MIMAKI Yoshihiro (90229790)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  HASHIMOTO Ken (70343457)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 4.  HAGIMOTO Yuri (30435078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 5.  KUSAMA Kaoru (20130479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  FUJISAWA Sei-ichtro (40014162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YOSHIDA Takashi (20025696)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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