ISHIKAWA Tsutomu 石川勉

Researcher Number	20114233
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2009 – 2011: Chiba University, 大学院・薬学研究院, 教授 2002 – 2004: 千葉大学, 大学院・薬学研究院, 教授 1997 – 1999: 千葉大学, 薬学部, 教授 1986 – 1991: 千葉大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Chemical pharmacy / Environmental pharmacy / Chemical pharmacy Except Principal Investigator Chemical pharmacy / 医薬分子機能学
Keywords	Principal Investigator ビスグアニジン / building block / asymmetric synthesis / aldehyde / aziridine / guanidinium ylide / chiral catalyst / guanidine / β-ラクタム / ネーバー反応 … More / キラル / 還元的開裂 / 環開裂 / エポキシド / 反応機構 / キラルグアニジン / スフィンゴシン / ビニルアルデヒド / グアニジニウム塩 / ビルディングブロック / 不斉合成 / アルデヒド / アジリジン / グアニジニウムイリド / キラル触媒 / グアニジン / 評価 / 分子設計 / 資源化学 / 環境化学 / X線結晶解析 / オルト置換ベンゼン / 回転エネルギー / 計算化学 / 光学分割 / 軸不斉 / キラルベンゼン / 分子結晶 / 合成 / 炭素イソスター / N-ヒドロキシホモアルギニン / N-ヒドロキシアルギニン / グアニジル基 / N-ニトロソウレイド基 / N-ヒドロキシグアニジル基 / 一酸化窒素 … More Except Principal Investigator ケレリスリン / 抗腫瘍性塩基 / 合成 / クライゼン転位 / フラン環の開裂 / Claisen rearrangement / Pueraria mirifica / タイ / Furan ring cleavage / Furan ring formation / Propargyl ether / Chelerythrine / Antitumor alkaloid / Synthesis / ベンゾ[C]フェナンスリジン / オルトホルミルフェノール / ケレリスリン型塩基 / シアノエチルピリジン / 抗腫瘍性 / ケリルビン / ファガリジン / ベンゾ(C)フェテンスリジン / フラン環開裂 / フラン環生成 / プロパルギルエ-テル / プロパルギルエーテル / ケレリスリン合成 / propargy ether / furan ring cleavage / antitumor active alkaloid / synthesis / Field Work / Endangered Plants / Medicinal Plants / Southeast Asia / 学術調査 / フィールドワーク / 絶滅危惧 / 薬用植物 / 東南アジア / Solid dispersion / Pharmaceutical technology / Evaluation of biological activity / Estrogenic activity / Natural Product Chemistry / Tropical Medicinal Resources / Thailand / 環境化学 / 分析化学 / 薬理学 / 固体分散 / 製剤工学 / 生物活性評価 / エストロゲン様作用 / Pueraria myrifica / 天然物化学 / 熱帯薬用資源 / Structure revision / 7, 8-Dimethoxycoumarin / 5, 8-Dimethoxycoumarin / Reisch's coumarin / Substituent effect / Coumarin synthesis / Wittig reagent / Salicylaldehyde / ホ-ナ-・エモンス反応 / ケイヒ酸エステル / 反応温度 / ウイッテイッヒ反応 / 5ーメトキシシュベレノン / トダレノン / ライシュクマリン / クマリン生成 / 構造訂正 / 7.8ージメトキシクマリン / 5.8ージメトキシクマリン / 7,8ージメトキシクマリン / 5,8ージメトキシクマリン / ライシユのクマリン / 置換基効果 / クマリン合成 / ヴィッティッヒ反応 / サリチルアルデヒド Less

Challenge to Environmental and Resource Chemistry : Preparation, Modification, and Assessment of Bisguanidine PolymersPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Tsutomu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental pharmacy
- Research Institution
  Chiba University
ビスグアニジン型分子結晶からの新知見:オルト置換ベンゼンは軸不斉化合物となり得るか?Principal Investigator
- Principal Investigator
  
  石川勉
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
New Guanidine ChemistryPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Tsutomu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Field Research on Southeast Asian Endangered Medicinal Plants
- Principal Investigator
  
  SEKINE Toshikazu
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  CHIBA UNIVERSITY
N-ヒドロキシグアニジン誘導体を基調とした一酸化窒素の有機化学的研究Principal Investigator
- Principal Investigator
  
  石川勉
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Utilization and Evaluation of Tropical Medicinal Resources
- Principal Investigator
  
  AIMI Norio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Molecular design and synthesis of coumarin by indexing
- Principal Investigator
  
  HARAYAMA Takashi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Synthetic Studies on the Antitumor Benzo[c]phenanthridine Alkaloids Directing toward Medicinals Development
- Principal Investigator
  
  ISHII Hisashi
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University
Synthesis of an antitumor active chelerythrine type alkaloid using Claisen rearrangement of a propargyl ether
- Principal Investigator
  
  ISHII Hisashi
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Chiba University

All 2012 2010 2005 2004 2003 2002

All Journal Article Presentation Patent

[Journal Article] o-Bisguanidinobenzene, a Powerful Hydrogen Acceptor : Crystal Structures of Organic Complexes with Benzoic Acid, Phenol, and Benzyl Alcohol2005
- Author(s)
  M.Kawahata, K.Yamaguchi, T.Ishikawa
- Journal Title
  
  Crystal Growth & Design 5
  
  Pages: 373-377
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] σ-Bisguanidine, a Powerful Hydrogen Acceptor : Crystal Structures of Organic Complexes with Benzoic Acid, Phenol and Benzyl Alcohol2005
- Author(s)
  M.Kawahata, K.Yamaguchi, T.Ishikawa
- Journal Title
  
  Crystal Growth & Design 5(1)
  
  Pages: 373-377
- Data Source
  KAKENHI-PROJECT-15659001
[Journal Article] Polymer-supported and Polymeric Chiral Guanidiens : Preparation and Application to the Asymmetric Michael Reaction of Iminoacetate with Methyl Vinyl Ketone2005
- Author(s)
  D.Wannaporn, T.Ishikawa
- Journal Title
  
  Molecular Diversity (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] Polymer-supported and Polymeric Chiral Guanidiens : Preparation andApplication to the Asymmetric Michael Reaction of Iminoacetate with Methy1 Viny1 Ketone2005
- Author(s)
  D.Wannaporn, T.Ishikawa
- Journal Title
  
  Molecular Deversity (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] o-Bisguanidinobenzene, a Powerful Hydrogen Acceptor : Crystal Structures of Organic Complexes with Benzoic Acid, Phenol, and Benzyl Alcohol2005
- Author(s)
  M.Kawahata, K.Yamaguchi, T.Ishikawa
- Journal Title
  
  Cryst.Grow.Desgin 5
  
  Pages: 373-377
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] Mechanistic Approaches to Asymmetric Synthesis of Aziridines from Guanidinium Ylides and Aryl Aldehydes2005
- Author(s)
  T.Haga, T.Ishikawa
- Journal Title
  
  Tetrahedron 61
  
  Pages: 2857-2869
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] Guanidines as a Nitrogen Source for Direct Conversion of Epoxides to Aziridine2004
- Author(s)
  Y.Tsuchiya, T.Kumamoto, T.Ishikawa
- Journal Title
  
  J.Org.Chem. 69
  
  Pages: 8504-8505
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] Structural Revision of the Ring-Opened Product in the ZnCl_2-Catalyzed Reactions of 1-Benzyl-2-phenylaziridine with Thiols2004
- Author(s)
  Y.Furuta, T.Kumamoto, T.Ishikawa
- Journal Title
  
  Synlett 2号
  
  Pages: 362-364
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] Structural Revision of the Ring-Opened Product in the ZnCl_2-Catalyzed Reactions of 1-Benzyl-2-phenylaziridine with Thiols2004
- Author(s)
  Y.Furuta, T.Kumamoto, T.Ishikawa
- Journal Title
  
  Synlett
  
  Pages: 362-364
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] Guanidines as a Nitrogen Source for Direct Conversion of Epoxides to Aziridiens2004
- Author(s)
  Y.Tsutiya, T.Kumamoto, T.Ishikawa
- Journal Title
  
  J.Org.Chem. 69巻
  
  Pages: 8504-8505
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] Guanidines as a Nitrogen Source for Direct Conversion of Epoxides to Aziridines2004
- Author(s)
  Y.Tsuchiya, T.Kumamoto, T.Ishikawa
- Journal Title
  
  Journal of Organic Chemistry 69
  
  Pages: 8504-8505
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] グアニジン型キラル補助剤2003
- Author(s)
  石川勉, 磯部敏男
- Journal Title
  
  有機合成化学協会誌 61
  
  Pages: 59-66
- NAID
  10011904428
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] Chiral Guanidines2003
- Author(s)
  T.Ishikawa, T.Isobe
- Journal Title
  
  J.Syn.Org.Chem.Jpn 61
  
  Pages: 59-66
- NAID
  10011904428
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] Guanidine-Assisted Asymmetric Synthesis2002
- Author(s)
  T.Ishikawa, T.Isobe
- Journal Title
  
  Chem.Eur.J. 8
  
  Pages: 552-557
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] Guanidine-Assisted Asymmetric Synthesis2002
- Author(s)
  T.Ishikawa, T.Isobe
- Journal Title
  
  Chemistry : European Journal 8
  
  Pages: 552-557
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] ニューグアニジンケミストリー-機能性の発掘を目指して-2002
- Author(s)
  石川勉
- Journal Title
  
  ファルマシア 38
  
  Pages: 505-507
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Journal Article] New Guanidine Chemistry-Toward Potential functions-2002
- Author(s)
  T.Ishikawa
- Journal Title
  
  Farumashia 38
  
  Pages: 505-507
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Patent] ビスグアニジン型化合物2004
- Inventor(s)
  石川勉, 川幡正敏
- Industrial Property Rights Holder
  科学技術振興機構, 千葉大学
- Industrial Property Number
  2004-146883
- Filing Date
  2004-05-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Patent] ビスグアニジン型化合物2004
- Inventor(s)
  石川勉, 川幡正俊
- Industrial Property Rights Holder
  千葉大学, 科学技術振興機構
- Industrial Property Number
  2004-146883
- Filing Date
  2004-05-17
- Data Source
  KAKENHI-PROJECT-15659001
[Patent] アジリジン類の製造方法2003
- Inventor(s)
  石川勉
- Industrial Property Rights Holder
  科学技術振興機構
- Industrial Property Number
  2003-057712
- Filing Date
  2003-03-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370717
[Presentation] 機能性ビスグアニジン化合部の合成2012
- Author(s)
  山崎浩平, 岸本海人, 石川勉
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21659029
[Presentation] 水質浄化を指向したビスグアニジン型機能性触媒の開発2010
- Author(s)
  岸本海人, 須田幸司, 熊本卓哉, 小椋康光, 石川勉
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21659029

1. WATANABE Toshiko (40120323)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. HARAYAMA Takashi (30025712)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ISHII Hisashi (70009166)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. AIMI Norio (30009170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SUZUKI Kazuo,t. (90109918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAKAGAWA Masako (40009171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. WATANABE Kazuo (80019124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAMAMOTO Keiji (50110341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SEKINE Toshikazu (70187855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. IKEGAMI Fumio (90159608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SEKI Hiroko (60114245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山口健太郎 (50159208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

ISHIKAWA Tsutomu 石川 勉

Research Projects

Research Products

Co-Researchers

Challenge to Environmental and Resource Chemistry : Preparation, Modification, and Assessment of Bisguanidine PolymersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ビスグアニジン型分子結晶からの新知見:オルト置換ベンゼンは軸不斉化合物となり得るか?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New Guanidine ChemistryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Field Research on Southeast Asian Endangered Medicinal Plants

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

N-ヒドロキシグアニジン誘導体を基調とした一酸化窒素の有機化学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Utilization and Evaluation of Tropical Medicinal Resources

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular design and synthesis of coumarin by indexing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthetic Studies on the Antitumor Benzo[c]phenanthridine Alkaloids Directing toward Medicinals Development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthesis of an antitumor active chelerythrine type alkaloid using Claisen rearrangement of a propargyl ether

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] o-Bisguanidinobenzene, a Powerful Hydrogen Acceptor : Crystal Structures of Organic Complexes with Benzoic Acid, Phenol, and Benzyl Alcohol2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] σ-Bisguanidine, a Powerful Hydrogen Acceptor : Crystal Structures of Organic Complexes with Benzoic Acid, Phenol and Benzyl Alcohol2005

Author(s)

Journal Title

Data Source

[Journal Article] Polymer-supported and Polymeric Chiral Guanidiens : Preparation and Application to the Asymmetric Michael Reaction of Iminoacetate with Methyl Vinyl Ketone2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Polymer-supported and Polymeric Chiral Guanidiens : Preparation andApplication to the Asymmetric Michael Reaction of Iminoacetate with Methy1 Viny1 Ketone2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] o-Bisguanidinobenzene, a Powerful Hydrogen Acceptor : Crystal Structures of Organic Complexes with Benzoic Acid, Phenol, and Benzyl Alcohol2005

Author(s)

Journal Title

ISHIKAWA Tsutomu 石川勉