TANAKA Yasuharu 田中康春

… Alternative Names

田中康春タカナヤスハル

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Researcher Number	20124878
Other IDs
Affiliation (based on the past Project Information) *help	2014 – 2015: 琉球大学, 医学部, 教授 2010 – 2012: 琉球大学, 医学部, 教授 2007 – 2008: University of the Ryukyus, 医学部, 教授 2003 – 2006: 奈良県立医科大学, 医学部, 助教授 2004: 奈良県立医科大学, 生化学, 助教授 1997: 奈良県立医科大学, 医学部, 講師 1996: 奈良県立医科大学, 生化学, 講師
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Surgical dentistry
Keywords	Principal Investigator NFκB / アポトーシス / 滑膜細胞 / Hsp70 / HIV-1 / 15d-PGJ2 / DNp73α / 伸展ストレス / p53 / 関節炎 … More / Cox-2 / グルコサミン / 変形性関節炎 / 15dPGJ2 / MMP / 関節リウマチ / 滑膜線維芽細胞 / DNp73 / COX-2 / 慢性関節リウマチ / 滑膜 / 炎症 / HSF1 / ΔNp73 / p73 / 持続感染 / ポリADPリボースポリメラーゼ … More Except Principal Investigator Cyclooxygenase-2(COX-2) / 滑膜細胞 / Nuclear factor-κB(NF-κB) / 顎関節症 / 培養滑膜細胞 / 機械的伸展 / Cyclooxygenase-2 (COX-2) / 顎関節 / Nuclear factor-κB (NF-κB) / Svnovial fibroblasts / Mechanical stretch / Temporomandibular joint (TMJ) / Nuclear factor κB(NF-κB) / Nuclear factorκB (NF-κB) / 培養滑膜細胞(HIG-82) / Nuclear factor-κΒ(NF-κΒ) / Synovial fibroblasts / Mechanical strech / Temporomandibular joint(TMJ) / Cyclppxygenase-2(COX-2) / Nuclearfactor-κB (NF-κB) / 顎関飾症 / 遺伝子発現 / 酸化ストレス / 歯学 Less

Activation mechanism of synovial cells: depression of p53-function by stretchingPrincipal Investigator
- Principal Investigator
  
  TANAKA Yasuharu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of the Ryukyus
The effect of the temporomandibular synovial cells bythe mechanical stretch
- Principal Investigator
  
  KAWAKAMI Tetsuji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nara Medical University
The responses of the temporomandibular synovial cells by the hydrostatic pressure
- Principal Investigator
  
  KAWAKAMI Tetsuji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nara Medical University
Hsp70の発現抑制による関節リウマチ滑膜細胞の増殖制御Principal Investigator
- Principal Investigator
  
  田中康春
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of the Ryukyus
Regulated factors of NF-kB activity in synovial fibroblasts by repetitive mechanical stretch
- Principal Investigator
  
  KAWAKAMI Tetsuji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nara Medical University
p73/ΔNp73を介した慢性関節リウマチ滑膜細胞増殖の制御Principal Investigator
- Principal Investigator
  
  田中康春
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nara Medical University
Response to synovial fibroblasts by various stresses
- Principal Investigator
  
  KAWAKAMI Tetsuji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nara Medical University
HIV-1持続感染成立に伴う感染細胞のアポトーシス感受性低下の分子機構Principal Investigator
- Principal Investigator
  
  田中康春
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nara Medical University
HIV-1持続感染成立に関わる宿主因子ポリADPリボースポリメラーゼPrincipal Investigator
- Principal Investigator
  
  田中康春
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nara Medical University

All 2015 2014 2011 2010 2009 2008 2007 2004 2003 Other

All Journal Article Presentation

[Journal Article] 15-Deoxy-Δ12, 14-prostaglandin J2 induces PPARγ- and p53-independent apoptosis in rabbit synovial cells2014
- Author(s)
  Sakaba Y, Awata H, Morisugi T, Kawakami T, Sakudo A, Tanaka Y
- Journal Title
  
  Prostaglandins Other Lipid Mediat
  
  Volume: 109-111 Pages: 1-13
- DOI
  10.1016/j.prostaglandins.2014.02.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25450447, KAKENHI-PROJECT-26670670
[Journal Article] Mechanical stretch enhance NF- κB-dependent gene expression and poly (ADP-ribose) synthesis in synovial cells2010
- Author(s)
  Morisugi T, Tanaka Y, Kawakami, Kirita T
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 147 Pages: 633-644
- NAID
  10027875563
- Data Source
  KAKENHI-PROJECT-22592227
[Journal Article] MMP-3 activation is a hallmark indicating an early change in TMJ disorders, and is related to nitration2009
- Author(s)
  Fujita H, Morisugi T, Tanaka Y, Kawakami T, Kirita T, Yoshimura Y
- Journal Title
  
  Int. J Oral Maxillofac Surg. 38
  
  Pages: 70-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592307
[Journal Article] MMP-3 activation is a hallmark indicating an early change in TMJ disorders, and is related to nitration.2009
- Author(s)
  Fujita T., Morisugi T., Tanaka Y., Kawakami T., Kirita T., Yosimura Y
- Journal Title
  
  Int. J. Oral Maxillofac. Surg. 38
  
  Pages: 70-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659385
[Journal Article] Heat stress promotes the degradation of p53 and p300/CBP-associated factor in murine embryonic fibroblasts2007
- Author(s)
  Tanaka Y., Morisugi T., and Hironaka A.
- Journal Title
  
  Ryukyu Med. J. 26
  
  Pages: 113-123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659385
[Journal Article] Heat stress promotes the degradation of p53 and p300/GBP-associated factor in murine embryonic fibroblasts.2007
- Author(s)
  Tanaka Y, Morisugi T, Hironaka A
- Journal Title
  
  Ryukyu Med. J. 26
  
  Pages: 113-123
- Data Source
  KAKENHI-PROJECT-19592307
[Journal Article] RNA interference directed against poly(ADP ribose) polymerase 1 efficiently suppresses human immunodeficiency virus type I replication in human cells2004
- Author(s)
  Kameoka, M., Nukuzuma, S., Itaya, A., Tanaka, Y.et al.
- Journal Title
  
  J.Virol. 78
  
  Pages: 8931-8934
- Data Source
  KAKENHI-PROJECT-15659359
[Journal Article] Regulation of HSF-1-responsive gene expression by N-terminal truncated form of p73α2004
- Author(s)
  Tanaka Y. et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 317
  
  Pages: 865-872
- Data Source
  KAKENHI-PROJECT-15659359
[Journal Article] Expression of histone acetyltransferases was down-regulateed in poly(ADP-ribose) polymerase-1-deficient murine cells.2003
- Author(s)
  Ota K., Kameoka M., Tanaka Y.et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 310
  
  Pages: 312-317
- Data Source
  KAKENHI-PROJECT-15659359
[Presentation] Analysis of poly(ADP-ribose)polymerase inhibitors isolated from Syzygium samarangens2015
- Author(s)
  屋嘉部、鎌田、玉那覇、下地、加藤、前泊、照屋、市場、田中
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド　（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26670670
[Presentation] 滑膜線維芽細胞における15デオキシプロスタグランジンで誘導されるPPARγ非依存的アポトーシス2011
- Author(s)
  田中康春
- Organizer
  第84回日本生化学学会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22592227
[Presentation] ウサギ滑膜線維芽細胞における機械的伸展に伴うNF-κBの活性化を介したCOX-2とiNOSの発現誘導2008
- Author(s)
  森杉敏明、川上哲司、田中康春、桐田忠昭
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19592307
[Presentation] Uniaxial mechanical stretch enhances expression of COX 2 and iNOS via activation of NFkB in rabbit synovial fibroblast.2008
- Author(s)
  森杉敏明, 田中康春, 川上哲司, 桐田忠
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  兵庫県神戸国際会議場
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19659385
[Presentation] 15-deoxy-Δ12,14-prostaglandin J2処理による核内ヒストンアセチルトランスフェラーゼ,PCAFのプロテアソームによる分解2007
- Author(s)
  広中安佐子、田中康春、土田澄代
- Organizer
  第30回日本分子生物学会年会、第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19659385
[Presentation] Enhancement of poly(ADP-ribose) synthesis in mouse embryonic fibroblast expressing HPV16 E6
- Author(s)
  西航、金城七代、島袋哲也、金城貴夫、田中康春
- Organizer
  日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26670670

1. KAWAKAMI Tetsuji (60254512)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. 吉原紘一朗 (70075042)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KAWAKAMI Masayoshi (20244717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 太田克矢 (60295798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 亀岡正典 (60281838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAKUDO Akikazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TANAKA Yasuharu 田中 康春

田中 康春 タカナ ヤスハル

Research Projects

Research Products

Co-Researchers

Activation mechanism of synovial cells: depression of p53-function by stretchingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of the temporomandibular synovial cells bythe mechanical stretch

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The responses of the temporomandibular synovial cells by the hydrostatic pressure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hsp70の発現抑制による関節リウマチ滑膜細胞の増殖制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulated factors of NF-kB activity in synovial fibroblasts by repetitive mechanical stretch

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

p73/ΔNp73を介した慢性関節リウマチ滑膜細胞増殖の制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Response to synovial fibroblasts by various stresses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HIV-1持続感染成立に伴う感染細胞のアポトーシス感受性低下の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

HIV-1持続感染成立に関わる宿主因子ポリADPリボースポリメラーゼPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] 15-Deoxy-Δ12, 14-prostaglandin J2 induces PPARγ- and p53-independent apoptosis in rabbit synovial cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanical stretch enhance NF- κB-dependent gene expression and poly (ADP-ribose) synthesis in synovial cells2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] MMP-3 activation is a hallmark indicating an early change in TMJ disorders, and is related to nitration2009

Author(s)

Journal Title

Data Source

[Journal Article] MMP-3 activation is a hallmark indicating an early change in TMJ disorders, and is related to nitration.2009

Author(s)

Journal Title

Data Source

[Journal Article] Heat stress promotes the degradation of p53 and p300/CBP-associated factor in murine embryonic fibroblasts2007

Author(s)

Journal Title

Data Source

[Journal Article] Heat stress promotes the degradation of p53 and p300/GBP-associated factor in murine embryonic fibroblasts.2007

TANAKA Yasuharu 田中康春

田中康春タカナヤスハル