YAMAKI Kunihiko 山木邦比古

… Alternative Names

山木邦比古ヤマキクニヒコ

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Researcher Number	20125751
External Links
Affiliation (Current)	2022: 日本医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2011 – 2013: 日本医科大学, 医学部, 教授 2007 – 2008: 日本医科大学, 医学部, 教授 2007: Nippon Medical School, Opthalmolocgy, Associate professor 2005 – 2006: Nippon Medical School, Medicine, Associate Professor, 医学部, 助教授 1996 – 2004: 秋田大学, 医学部, 助教授 1991 – 1994: 秋田大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Ophthalmology / Ophthalmology Except Principal Investigator Ophthalmology / Ophthalmology / Clinical veterinary science
Keywords	Principal Investigator VKH disease / 原田病特異抗原 / Tyrosinase / T cell clone / cDNAクローニング / メラノサイト特異蛋白質 / Tyrosinase family protein / MHC / Expression / 樹状細胞 … More / dendritic cell / TCR / 原田病 / 自己免疫 / Molecular cloning / モレキュラークローニング / 発現 / 蛋白の局在 / 原田病特異的MHC / Tyrosinase related protein1 / Tyrosinase related protein 2 / 実験的自己免疫性ぶどう膜炎 / Vogt-Koyama-Harada病 / 実験的VKH disease / Tyrosinse family protein / T細胞の反応性 / T細胞クローン / Tyrosinse family Protein / 実験的VKHdisease / Experimental VKH disease / Reactivity of the T cells / トランスジェニックラット / Transgenic rats / Tyrosinese family protein / Animal model / Tyrosinase TRP1 / CD4 T cell(Th1 cell) / TCRCT cell receptor / Tyrosinase family proteins / animal model / 抗原提示細胞 / T細胞 / 調節性樹状細胞 / 抗原提示 / T cell / in vitro priming / TRP1 / Antigen presenting cells / T cells / Regulatory dendritic cells / 特異抗体 / VKHdisease / 特異的免疫反応 / 特異的抗体 / Antigen specific for / Speific immune response … More Except Principal Investigator VKH disease / T cell clone / Mfrp / Clqtnf5 / C1qtnf5 / RPE65 / EAU / Tyrosinase family proteins / T cell / animal model / 遺伝学 / 加齢黄斑変性症 / neuromyelitis optica / alpha1-syntrophin / 視神経脊髄炎 / α1-syntrophin / 網膜特異的抗原 / 実験的自己免疫性ぶどう膜炎 / トランスジェニック / トランスジエニック / トランスジェニックマウス / ノックアウトマウス / Autoimmune uveo-retinitis / Retina specific antigens / Transgenic rats / 実験的ぶどう膜(EAU) / peptide / リンパ球増殖試験 / 実験的ぶどう膜炎(EAU) / PRE65 / pigmented rat / PEPTIDES / AUTOREACTIVE T CELLS / Dendritic Cell / Tyrosinase related protein 1 / Animal model / Tyrosinase TRP1 / T cell clonl / 前房水 / auto reactive T cell / Tyrosinase family protein / vKH disease / Aqueous humor / CSF / yrosinase family protein / Inflammatory lesions / 原田病 / 自己免疫疾患 / メラノサイト / 秋田犬 / ぶどう膜炎 / モンゴロイド / イヌ / カニクイザル / 自己免疫 / サル / HLA-DR4 / Vogt-Koyanagi-Harada disease / VKH / Akita dog / tyrosinase related protein / TRP / Experimentally model / uveitis / intraocular inflammation / rd6マウス Less

Determination of disease causing mechanisms of neuromyelitis optica by analyzing alpha1-syntrophin deficient mice
- Principal Investigator
  
  KAMEYA SHUHEI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Nippon Medical School
Production and analysis of the mouse model of age-related macular degeneration with disruption of C1qtnf5
- Principal Investigator
  
  KAMEYA Shyuhei
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Nippon Medical School
Development of diagnostic tools and treatment based on the specific immune responses of VKH diseasePrincipal Investigator
- Principal Investigator
  
  YAMAKI Kunhiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Nippon Medical School
Analysis of interaction among proteins expressed in retinal pigment epithelium
- Principal Investigator
  
  KAMEYA Shuhei
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Nippon Medical School
Establishment of antigen specific regulatory dendritic cells and treatment of VKH disease with these dendritic cellsPrincipal Investigator
- Principal Investigator
  
  YAMAKI Kunihiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Nippon Medical School
  Akita University
Experimentally induced Vogt-Koyanagi-Harada disease in two Akita dogs
- Principal Investigator
  
  ITOH Norihiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical veterinary science
- Research Institution
  School of Medicine, Yokohama City University
Molecular immune mechanisum of VKH disease.
- Principal Investigator
  
  HAYAKAWA Kouichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  AKITA UNIVERSITY
Molecular immunological investigation of animal model of Vogt-Koyanagi-Harada disease
- Principal Investigator
  
  SAKURAGI Shozo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  AKITA UNIVERSITY
Molecular immunological investigation of Vogt-Koyanagi-Harada diseasePrincipal Investigator
- Principal Investigator
  
  YAMAKI Kunihiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  AKTTA UNIVERSITY
Molecurar immunological study of VKH diseasePrincipal Investigator
- Principal Investigator
  
  YAMAKI Kunihiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  AKITA UNIVERSITY
The potential of RPE65 for EAU and autoimmune disease against RPE
- Principal Investigator
  
  KONDO Isao
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  AKITA UNIVERSITY
Molecular Immunology study of t
- Principal Investigator
  
  SAKURAGI Shozo
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  AKITA UNIVERSITY
THE ANALYSIS OF THE VKH DISEASE SPECIFIC ANTIGEN - SDS INSOLUBLE PROTEINPrincipal Investigator
- Principal Investigator
  
  YAMAKI Kunihiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  AKITA UNIVERSITY
VKH disease・原田病特異的抗原の検索-SDS不溶性成分の検索Principal Investigator
- Principal Investigator
  
  山木邦比古
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Akita University
原田病の分子免疫学的研究Principal Investigator
- Principal Investigator
  
  山木邦比古
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Akita University
原田病の分子免疫学的研究Principal Investigator
- Principal Investigator
  
  山木邦比古
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Akita University
原田病の分子免疫学的研究(抗原の決定とクロ-ニングを中心として)Principal Investigator
- Principal Investigator
  
  山木邦比古
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Akita University
原田病の分子免疫学的研究(原田病特異抗原の発現、解析と原田病患者MHCの解析)Principal Investigator
- Principal Investigator
  
  山木邦比古
- Project Period (FY)
  1989 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Akita University

All 2008 2007 2005

All Journal Article Presentation

[Journal Article] 眼内炎症反応の成立と抗原提示過程2008
- Author(s)
  山木邦比古
- Journal Title
  
  日本医科大学医学会雑誌 4
  
  Pages: 8-14
- NAID
  130004941905
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591939
[Journal Article] 眼内炎症反応の成立と抗原提示過程2008
- Author(s)
  山木邦比古
- Journal Title
  
  日本医科大学医学会雑誌 4
  
  Pages: 8-14
- NAID
  130004941905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591939
[Journal Article] Experimentally induced Vogt-Koyanagi-Harada disease in two Akitadogs2005
- Author(s)
  Yamaki K, Takiyama N, Itoh N, et al.
- Journal Title
  
  Exp.Eye Res. (In press)
- Data Source
  KAKENHI-PROJECT-15580290
[Journal Article] Application of revised diagnostic criteria for vogt-koyanagi-harada disease in Japanese patients.2005
- Author(s)
  Yamaki K, Hara K, Sakuragi S
- Journal Title
  
  Jpn J Ophthalmol. 49
  
  Pages: 143-148
- NAID
  10016484900
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591739
[Journal Article] Experimentally induced Vogt-Koyanagi-Harada disease in two Akita dogs.2005
- Author(s)
  Yamaki K, Takiyama N, Itoh N, Mizuki N, Seiya M, Sinsuke W, Hayakawa K, Kotani T.
- Journal Title
  
  Experimental Eye Research. 80
  
  Pages: 273-280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591739
[Journal Article] Experimentally induced Vogt-Koyanagi-Harada disease in two Akita dogs2005
- Author(s)
  Kunihiko Yamaki, Naoaki Takiyama, Norihiko Itho, Nobuhisa Mizuki, Maehara Seiya, Wakaiki Sinsuke, Kouichi Hayakawa, Tadao Kotani
- Journal Title
  
  Experimental Eye Research 80
  
  Pages: 273-280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580290
[Journal Article] Application of revised diagnostic criteria for vogt-koyanagi-harada disease in Japanese patients.2005
- Author(s)
  Yamaki K, Hara K, Sakuragi S
- Journal Title
  
  Jpn J Ophthalmol 49
  
  Pages: 143-148
- NAID
  10016484900
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591739
[Journal Article] Experimental autoimmune uveitis induced by immunization with retinal pigment epitelium-specific 65kDa protein peptides2005
- Author(s)
  Nakamura H, Yamaki K, Kondo I, Sakuragi S
- Journal Title
  
  Curr Eye 30
  
  Pages: 673-680
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591739
[Journal Article] 1.Application of revised diagnostic criteria for vogt-koyanagi-harada disease in Japanese patients.2005
- Author(s)
  Yamaki k, Hara K, Sakuragi S
- Journal Title
  
  Jpn J Ophthalmol 49
  
  Pages: 143-148
- Data Source
  KAKENHI-PROJECT-16591739
[Journal Article] Experimentally induced Vogt-Koyanagi-Harada disease in two Akita dogs2005
- Author(s)
  Yamaki K, Takiyama N, Itoh N, Mizuki N, Seiya M, Sinsuke W, Hayakawa K, Kotani T.
- Journal Title
  
  Experimental Eye Research 80
  
  Pages: 273-280
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591739
[Journal Article] Experimentally induced Vogt-Koyanagi-Harada disease in two Akita dogs2005
- Author(s)
  Yamaki k, Takiyama N, Itoh N, Mizuki N, Seiya M, Sinsuke W, Hayakawa K, Kotani T.
- Journal Title
  
  Experimental Eye Research 80
  
  Pages: 273-280
- Data Source
  KAKENHI-PROJECT-16591739
[Journal Article] Experimental autoimmune uveitis induced by immunization with retinal pigment epitelium-specific 65kDa protein peptides.2005
- Author(s)
  Nakamura H, Yamaki K, Kondo I, Sakuragi S
- Journal Title
  
  Curr.Eye. 30
  
  Pages: 673-680
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591739
[Journal Article] Experimentally induced Vogt-Koyanagi-Harada disease in two Akitadogs2005
- Author(s)
  Yamaki K, Takiyama N, Itoh N, et al
- Journal Title
  
  Exp.Eye Res. 80
  
  Pages: 273-280
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580290
[Journal Article] Experimental autoimmune uveitis induced by immunization with retinal pigment epitelium-specific 65kDa protein petides2005
- Author(s)
  Nakamura H, Yamaki K, Kondo I, Sakuragi S
- Journal Title
  
  Curr Eye 30
  
  Pages: 673-680
- Data Source
  KAKENHI-PROJECT-16591739
[Presentation] Cytotoxity of TCLs and TCC from aqueous humors and/or CSF with acute and fresh stage of VKH disease2007
- Author(s)
  Kunihiko Yamaki
- Organizer
  5th International workshop on Vogt-Koyanagi-Harada disease and Sympathetic Ophthalmia
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591939

1. KONDO Isao (50234927)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. KAMEYA Shyuhei (30302269)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. SAKURAGI Shozo (80006767)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. KONNO Seiki (00312710)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. 中村敏

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. HAYAKAWA Kouichi (80312700)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. GOTO Yoko (80277524)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 菅原由美 (20250889)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 石川誠 (10212854)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 中村秀夫 (20282189)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 小山ゆかり

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 山形和正

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. SUZUKI Yuko (00342931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKAHASHI Hisatomo (10445801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKEDA Shinichi (90171644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ITOH Norihiko (80264654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 徐魁イ (70272036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 原宏二 (60375251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAKI Kunihiko 山木 邦比古

山木 邦比古 ヤマキ クニヒコ

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Development of diagnostic tools and treatment based on the specific immune responses of VKH diseasePrincipal Investigator

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Establishment of antigen specific regulatory dendritic cells and treatment of VKH disease with these dendritic cellsPrincipal Investigator

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Molecular immunological investigation of Vogt-Koyanagi-Harada diseasePrincipal Investigator

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Molecurar immunological study of VKH diseasePrincipal Investigator

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THE ANALYSIS OF THE VKH DISEASE SPECIFIC ANTIGEN - SDS INSOLUBLE PROTEINPrincipal Investigator

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VKH disease・原田病特異的抗原の検索-SDS不溶性成分の検索Principal Investigator

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YAMAKI Kunihiko 山木邦比古

山木邦比古ヤマキクニヒコ