OHASHI Kyoichi 大橋京一

Researcher Number	20137714
Other IDs
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Affiliation (based on the past Project Information) *help	2014: 大分大学, 副学長 2013: 大分大学, 法人本部, 理事・副学長 2011: 大分大学, 医学部・臨床薬理学, 教授 2010 – 2011: 大分大学, 医学部, 教授 2009: Oita University, 医学部・臨床薬理学, 教授 … More 2007 – 2008: Oita University, 医学部, 教授 2005: Oita University, Faculty of Medicine, professor, 医学部, 教授 2004: 国立大学法人浜松医科大学, 医学部, 教授 2003: Hamamatsu Medical University, School of Medicine, Professor, 医学部・臨床薬理学, 教授 2002 – 2003: 浜松医科大学, 医学部, 教授 2001: Hamamatsu Med. Univ., Prof., 教授 1998 – 2000: 浜松医科大学, 医学部, 教授 Less
Review Section/Research Field	Principal Investigator Applied pharmacology / 応用薬理学・医療系薬学 Except Principal Investigator Neurology / 応用薬理学・医療系薬学 / Applied pharmacology
Keywords	Principal Investigator 遺伝子多型 / UGT2B7 / オピオイド鎮痛薬 / morphine / モルヒネ / genetic polymorphism / omeprazole / CYP2C19 / オピオイド受容体 / オピオイド … More / ゲノム / opioid receptor / pharmacogenetics / 薬物動態 / intragastric pH / Helicobactor pylori / proton pump inhibitor / 胃内pH / Helicobacter pylori / プロトンポンプ阻害薬 / ブプレノルフィン / COMT / 個別化治療 / μ受容体 / 薬剤反応性 / MDR1 / OPRM1 / 薬物反応性 … More Except Principal Investigator polymorphism / CYP / L-dopa / drug interaction / トランスポーター / dopamine receptor agonist / Transporters / Pharmacokinetics / Parkinson's disease / 候補遺伝子 / 薬物反応 / superhealth family / transporter / 臨床経過 / bioavailability / 治療薬 / 発症規定因子 / アマンタジン / ドパミン受容体アゴニスト / 個体差 / パーキンソン病 / enzyme inhibition / drug metabolism / grapefruit juice / グレープフルーツジュース / 酵素相互 / 薬物代謝 / 薬物相互作用 / グループフルーツジュース / 韓国 / 中国 / 国際情報交換 / MRP4 / OATP / 薬物トランスポーター / 代謝酵素 / 内的要因と外的要因 / 薬物動態 / アジアにおける民族差 / 外的要因 / 遺伝子多型 / 民族差 / 東アジア / 医薬品応答性 Less

オピオイド鎮痛薬の個人差に影響するオピオイド神経系の臨床薬理遺伝学研究Principal Investigator
- Principal Investigator
  
  大橋京一
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Oita University
What factors affect the ethnicity in drug response?: East Asian collaborative study
- Principal Investigator
  
  KOTEGAWA Tsutomu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Oita University
Clinical Usefulness and evaluation of pharmacogenetics on the personalized therapy of opioid analgesics.Principal Investigator
- Principal Investigator
  
  OHASHI Kyoichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Oita University
The usefulness for pharmacogenetic informations of opioid analgesics in the individualized pain therapyPrincipal Investigator
- Principal Investigator
  
  OHASHI Kyoichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Oita University
Effects of morphine-related genotypes on the individualized morphine treatment in cancer patientsPrincipal Investigator
- Principal Investigator
  
  OHASHI Kyoichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Oita University
  Hamamatsu University School of Medicine
Research on the factor causing indivisual fifference Parkinson's disease
- Principal Investigator
  
  NOMOTO Masaniro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Ehime University
Effect of genetic polymorphism of UGT2B7 on pharmacokinetics of morphine in cancer patientsPrincipal Investigator
- Principal Investigator
  
  OHASHI Kyoichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
Grapefruit juice-drug interaction and the prediction
- Principal Investigator
  
  YAMAZOE Yasushi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
The clinical relevance of CYP2C19 genotype status on the rational drug treatmentPrincipal Investigator
- Principal Investigator
  
  OHASHI Kyoichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Hamamatsu University School of Medicine

All 2008 2007 2005 2004 2003

All Journal Article

[Journal Article] ファーマコゲノミクスの臨床薬理学からみた最前線2008
- Author(s)
  大橋京一、今井浩光
- Journal Title
  
  19-1
  
  Pages: 13-17
- Data Source
  KAKENHI-PROJECT-19590540
[Journal Article] ファーマコゲノミクスの臨床薬理学からみた最前線2008
- Author(s)
  大橋京一(第1著者), 今井浩光(第2著者)
- Journal Title
  
  ヒューマンサイエンス 19-1
  
  Pages: 13-17
- Data Source
  KAKENHI-PROJECT-19590540
[Journal Article] モルヒネのPharmacogenetics-癌疼痛緩和療法の個別化に向けて-2007
- Author(s)
  大橋京一
- Journal Title
  
  臨床薬理の進歩 28
  
  Pages: 35-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590540
[Journal Article] モルヒネのPharmacogenetics-癌疼痛緩和療法の個別化に向けて-2007
- Author(s)
  大橋京一、立石正登、内田信也
- Journal Title
  
  臨床薬理の進歩 28巻
  
  Pages: 35-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590540
[Journal Article] モルヒネの薬効におけるμ受容体遺伝子多型2005
- Author(s)
  立石正登, 内田信也, 江口研二, 兵頭一之介, 大橋京一
- Journal Title
  
  臨床薬理 36Suppl
  
  Pages: 185-185
- Data Source
  KAKENHI-PROJECT-16590436
[Journal Article] モルヒネの薬効におけるμ受容体遺伝子多型2005
- Author(s)
  立石正登, 内田信也, 江口研二, 兵頭一之介, 大橋京一
- Journal Title
  
  臨床薬理 36 Suppl
  
  Pages: 185-185
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590436
[Journal Article] モルヒネ効果の個人差は酵素や受容体の遺伝子多型が関与か2004
- Author(s)
  大橋京一, 立石正登
- Journal Title
  
  メディカル朝日 9月号
  
  Pages: 40-41
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590436
[Journal Article] Are polymorphism of metabolized enzyme and receptor influenced interindividual effect of morphine?2004
- Author(s)
  Ohashi K, Tateishi M
- Journal Title
  
  Medical Asahi Sep.
  
  Pages: 40-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590436
[Journal Article] モルヒネ効果の個人差は酵素や受容体の遺伝子多型が関与か2004
- Author(s)
  大橋京一, 立石正登
- Journal Title
  
  メディカル朝日 9
  
  Pages: 40-41
- Data Source
  KAKENHI-PROJECT-16590436
[Journal Article] Interindividual variation in the ratio between plasma morphine and its metabolites in cancer patients.2003
- Author(s)
  Tateishi M, Ohashi K, Kobayashi K, Hashimoto T, Yamaguchi J, Fujioka H, Izawa K, Masada M
- Journal Title
  
  Int J Clin Pham Res 23
  
  Pages: 75-82
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590436
[Journal Article] Interindividual variation in the ratio between plasma morphine and its metabolites in cancer patients.2003
- Author(s)
  Tateishi M, Ohashi K, Kobayashi K, Hashimoto T, Yamaguchi J, Fujioka H, Izawa K, Masada M
- Journal Title
  
  Int J Clin Pharm Res 23
  
  Pages: 75-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590436

1. UCHIDA Shinya (80372522)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. IMAI Hiromitsu (30398250)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
3. NOGUCHI Takayuki (90156183)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TATEISHI Masato (20446123)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. KOTEGAWA Tsutomu (20264343)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. KOSUGE Kazuhiro (00283375)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ITO Hiroaki (70443447)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HASHIMOTO Hisakuni (10009558)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. SHIRAO Kuniaki (10467996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MORIMOTO Takuya (10392242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TSUTSUMI Kimiko (20244171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OHYAMA Tetsuji (60574085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FURUTA Takahisa (10303546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YAMAZOE Yasushi (00112699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAGATA Kiyoshi (80189133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NOMOTO Masaniro (50208401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MIKI Tetsuro (00174003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. EGUCHI Kenji (30349336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. HYODO Ichinosuke (60416469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. FUKUDA Katsuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OHASHI Kyoichi 大橋 京一

Research Projects

Research Products

Co-Researchers

オピオイド鎮痛薬の個人差に影響するオピオイド神経系の臨床薬理遺伝学研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

What factors affect the ethnicity in drug response?: East Asian collaborative study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical Usefulness and evaluation of pharmacogenetics on the personalized therapy of opioid analgesics.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The usefulness for pharmacogenetic informations of opioid analgesics in the individualized pain therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of morphine-related genotypes on the individualized morphine treatment in cancer patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the factor causing indivisual fifference Parkinson's disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of genetic polymorphism of UGT2B7 on pharmacokinetics of morphine in cancer patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Grapefruit juice-drug interaction and the prediction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The clinical relevance of CYP2C19 genotype status on the rational drug treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ファーマコゲノミクスの臨床薬理学からみた最前線2008

Author(s)

Journal Title

Data Source

[Journal Article] ファーマコゲノミクスの臨床薬理学からみた最前線2008

Author(s)

Journal Title

Data Source

[Journal Article] モルヒネのPharmacogenetics-癌疼痛緩和療法の個別化に向けて-2007

Author(s)

Journal Title

Data Source

[Journal Article] モルヒネのPharmacogenetics-癌疼痛緩和療法の個別化に向けて-2007

Author(s)

Journal Title

Data Source

[Journal Article] モルヒネの薬効におけるμ受容体遺伝子多型2005

Author(s)

Journal Title

Data Source

[Journal Article] モルヒネの薬効におけるμ受容体遺伝子多型2005

Author(s)

OHASHI Kyoichi 大橋京一