Konishi Masato 小西真人

… Alternative Names

KONISHI Masato 小西真人

小西真人

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Researcher Number	20138746
Other IDs	https://orcid.org/0009-0005-7559-9630
External Links
Affiliation (Current)	2025: 東京医科大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2006 – 2008: 東京医科大学, 医学部, 教授 2001 – 2004: 東京医科大学, 医学部, 教授 1999: Tokyo Medical University, Department of Physiology, Professor, 医学部, 教授 1992 – 1998: The Jikei University School of Medicine, Department of Physiology, Associate Professor, 医学部, 助教授 1991: 東京慈恵会医科大学, 医学部, 講師 1986: 東京慈恵会医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator General physiology / General physiology Except Principal Investigator General physiology / Neurophysiology and muscle physiology
Keywords	Principal Investigator 心筋 / マグネシウム / 平滑筋 / Na-Mg交換輸送 / 蛍光Mg指示薬 / 交換輸送 / Cardiac muscle / 細胞内Mg濃度 / 骨格筋 / 細胞内マグネシウム … More / 膜輸送 / 細胞内Mg / functional analysis of membrane transprot / cardiac myocytes / molecular cloning / Na-Mg exchange / fluorescent Mg indicator / Mg-tolerant cells / Mg transport / intracellular Mg concentration / Mg耐性 / Na / Mg輸送体 / 膜輸送の機能解析 / 心筋細胞 / 分子クローニング / Mg耐性細胞 / Mg汲み出し輸送 / 細胞内遊離Mg濃度 / antiport / NaィイD1+ィエD1-MgィイD12+ィエD1 exchange / NaィイD1+ィエD1-CaィイD12+ィエD1 exchange / Smooth muscle / Transporter / Sodium / Magnesium / 細胞内Na濃度 / 平滑筋細胞 / 盲腸紐 / モルモット / Na-Ca交換輸送 / 細胞内Ca濃度 / Na-Mg交換 / Na-Ca交換 / ナトリウム / beta-escin / Fluorescent Ca indicator / Intracellular calcium concentration / Muscle / 螢光カルシウム指示薬 / beta-エスチン / alpha毒素 / カルシウムイオン / 骨格筋細胞 / Ca指示薬 / カルシウム濃度 / Intracellular ATP / Acidosis / Fluorescent Mg indicator / Intracellular magnesium / Skeletal muscle / NaーMg交換系 / 骨格筋線維 / furaptra / Mg指示薬 / 細胞内ATP / アシドーシス / 螢光マグネシウム指示薬 / 数理モデル / システム解析 / マグネシウム輸送体 / マグネシウム透過チャネル / ATP / 筋小胞体 / 細胞内pH / 蛍光マグネシウム指示薬 … More Except Principal Investigator 細胞内Ca / エクオリン / Caffeine / Intracellular calcium / Skeletal muscle / Aequorin / 単収縮 / 強縮 / カフェイン / 細胞内カルシウムイオン / 骨格筋 / カテコールアミン / リアノジン / 心筋 / 第49回日本平滑筋学会総会 / Susan Wray / Jan Huizinga / 第84回日本生理学会大会 / 特定領域研究 / 調節機構 / ユビキタスペースメーカ / ペースメーカ活動 / カルシウム濃度測定 / ケイジド化合物 / 光分解 / 多光子励起 Less

Regulation of intracellular magnesium concentrationPrincipal Investigator
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Medical University
自律神経系ペースメーカ機構の拡がり
- Principal Investigator
  
  高木都
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Nara Medical University
Identification of magnesium transporter molecules and functional analysis with high temporal/spatial resolution.Principal Investigator
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Medical University
細胞内局所イベントが作り出すグローバルな細胞・組織機能-改良型ケイジドCa^<2+>多光子レーザー分解および局所Ca^<2+>定量法の確立と応用-
- Principal Investigator
  
  國分眞一朗
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Nihon University
Identification and quantitative analysis of the cell membrane MgィイD1[2+]ィエD1 transporter in cardiac and smooth muscles.Principal Investigator
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Medical University
  Jikei University School of Medicine
心筋・平滑筋細胞におけるCa遊離・収縮の細胞内Mgによる制御Principal Investigator
- Principal Investigator
  
  小西真人
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine
血管平滑筋細胞内Mgの変動とその生理的役割の解明Principal Investigator
- Principal Investigator
  
  小西真人
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Jikei University School of Medicine
A Novel Method to Quantify Intracellular Free Calcium Concentration in Muscle Cells with a Fluorescent Indicator.Principal Investigator
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  The Jikei University School of Medicine
Optical Measurements of Intracellular Free Magnesium Concentration in Skeletal and Cardiac Muscle CardiacPrincipal Investigator
- Principal Investigator
  
  KONISHI Masato
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  The Jikei University School of Medicine
光学的方法による単一心筋細胞内遊離Ca濃度測定と興奮-収縮連関機構の解明
- Principal Investigator
  
  KURIHARA Satoshi
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Jikei University School of Medicine
Study of intracellular calcium movement by time resolved image processing method.
- Principal Investigator
  
  KURIHARA Satoshi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  The Jikei University School of Medicine

All 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation

[Journal Article] Differential effects of an expected actin-tropomyosin binding region of heat shock protein 20 on the relaxation in skinned carotid artery and taenia cecum from guinea pig2009
- Author(s)
  Hashimoto, R., Yumoto, M., Watanabe, M., Konishi, M., Haraoka, J. and Miki, T.
- Journal Title
  
  Journal of Smooth Muscle Research 45
  
  Pages: 63-74
- NAID
  130000860930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390066
[Journal Article] Metabolic inhibition largely diminishes Na^+-Mg^<2+> exchange in rat ventricular myocytes.2007
- Author(s)
  Masato Konishi
- Journal Title
  
  Biophysical Journal 92
- Data Source
  KAKENHI-PROJECT-18390066
[Journal Article] Mechanisms of the inhibitory effects of a phenoxazine compound, 2-amino-4,4α-dihydro-4α-7-dimethyl-3 H-phenoxazine-3-one, on the contraction of the smooth muscle of the guinea pig taenia cecum2007
- Author(s)
  Musha, S., Watanabe, M., Tomoda, A. and Konishi, M.
- Journal Title
  
  Journal of Smooth Muscle Research 43
  
  Pages: 15-24
- NAID
  110006277704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390066
[Journal Article] Na^+/Mg^<2+> exchange as an active extrusion pathway of cellular magnesium.2006
- Author(s)
  Masato Konishi
- Journal Title
  
  Journal of Japanese Society for Magnesium Research 25
  
  Pages: 117-117
- Data Source
  KAKENHI-PROJECT-18390066
[Journal Article] Effects of intracellular and extracellular concentrations of Ca^<2+>, K^+ and Cl^-on the Na^+-dependent Mg^<2+> efflux in rat ventricular myocytes2006
- Author(s)
  Tashiro, M., Tursun, P., and Konishi, M.
- Journal Title
  
  Biophysical Journal 91
  
  Pages: 244-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390066
[Journal Article] Use of the Ca-shortening curve to estimate the myofilament responsiveness to Ca^<2+> in tetanized rat ventricular myocytes2006
- Author(s)
  Kusakari, Y., Hongo, K., Kawai, M., Konishi, M. and Kurihara, S.
- Journal Title
  
  Journal of Physiological Sciences 56
  
  Pages: 219-226
- NAID
  10020331576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390066
[Journal Article] Cell membrane transport of Mg2+ (in Japanese).2005
- Author(s)
  Konishi, M.
- Journal Title
  
  Clinical Calcium 15
  
  Pages: 89-94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] Modulation of Mg2+ efflux from rat ventricular myocytes studied with the fluorescent indicator furaptra.2005
- Author(s)
  Tursun, P., Tashiro, M., Konishi, M.
- Journal Title
  
  Biophysical Journal 88
  
  Pages: 1911-1924
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] 膜輸送とマグネシウム2005
- Author(s)
  小西真人
- Journal Title
  
  Clinical Calcium 15
  
  Pages: 89-94
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] Mg2+ transport by the Na+-Mg2+ exchange (in Japanese).2004
- Author(s)
  Konishi, M.
- Journal Title
  
  Clinical Calcium 14
  
  Pages: 37-40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] P2Y-mediated Ca2+ response is spatio-temporally graded and synchronized in sensory neurons: a two-photon excitation study.2004
- Author(s)
  Nakayama, S., Yamashita, T., Konishi, M., Kazama, H., Kokubun, S.
- Journal Title
  
  FASEB Journal 18
  
  Pages: 1562-1564
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] Effects of hydrogen peroxide on contraction of skinned aorta from guinea pig.2003
- Author(s)
  Sakurai, W., Watanabe, M., Yamashina A., Konishi, M.
- Journal Title
  
  Japanese Journal of Physiology 53
  
  Pages: 471-474
- NAID
  10012733201
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] The mechanism of increasing Ca2+ responsiveness by α1-adrenoceptor stimulation in rat ventricular myocytes.2002
- Author(s)
  Kusakari, Y., Hongo, K., Kawai, M., Konishi, M., Kurihara S.
- Journal Title
  
  Japanese Journal of Physiology 52
  
  Pages: 531-539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] Effects of membrane potential on Na+-dependent Mg2+ extrusion from rat ventricular myocytes.2002
- Author(s)
  Tashiro, M.Pulat Tursun, Miyazaki, T., Watanabe, M., Konishi, M.
- Journal Title
  
  Japanese Journal of Physiology 52
  
  Pages: 541-551
- NAID
  130004435853
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] Urinary excretion of Magnesium (in Japanese).2002
- Author(s)
  Konishi, M., Watanabe, M., Tashiro, M.
- Journal Title
  
  Journal of Japanese Society for Magnesium Research 52
  
  Pages: 531-539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] Use of tetanus to investigate myofibrillar responsiveness to Ca2+ in isolated mouse ventricular myocytes.2002
- Author(s)
  Hongo, K., Kusakari, Y., Kawai, M., Konishi, M., Kurihara, S., Mochizuki S.
- Journal Title
  
  Japanese Journal of Physiology 52
  
  Pages: 121-127
- NAID
  10008296133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370016
[Journal Article] Metabolic inhibition strongly inhibits Na^+-dependent Mg^<2+> efflux in rat ventricular myocytes
- Author(s)
  Tashiro, M., Inoue, H. and Konishi, M.
- Journal Title
  
  Biophysical Journal (in press)
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] Is ATP required for activities of the Na^+/Mg^<2+> exchange?2009
- Author(s)
  Tashiro, M., Inoue, H. and Konishi, M.
- Organizer
  53rd Annual Meeting of the Biophysical Society
- Place of Presentation
  Boston, Massachusetts, U.S.A.
- Year and Date
  2009-03-04
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] 心筋細胞内Mg^<2+>濃度制御2008
- Author(s)
  小西真人, 田代倫子, 井上華
- Organizer
  第28回日本マグネシウム学会総会シンポジウム"マグネシウムの輸送"
- Place of Presentation
  広島
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] Metabolic inhibition of cardiac myocytes causes a large increase in intracellular Mg^<2+> concentration by breakdown of ATP and inhibition of Mg^<2+> transport2008
- Author(s)
  田代倫子、小西真人
- Organizer
  第31回心筋代謝研究会
- Place of Presentation
  東京
- Year and Date
  2008-07-13
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] ラット心室筋細胞におけるナトリウム依存性マグネシウム汲み出し輸送に対する代謝阻害と細胞内Phの影響2008
- Author(s)
  田代倫子、小西真人
- Organizer
  第85回日本生理学会
- Place of Presentation
  東京
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] 心筋代謝阻害時のNa^+/Mg^<2+>交換輸送活性2007
- Author(s)
  田代倫子、小西真人
- Organizer
  第84回日本生理学会
- Place of Presentation
  大阪
- Year and Date
  2007-03-20
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] Metabolic inhibition largely diminishes Na^+-Mg^<2+> exchange in rat ventricular myocytes2007
- Author(s)
  Konishi, M. and Tashiro M.
- Organizer
  51st Annual Meeting of the Biophysical Society
- Place of Presentation
  Baltimore, Maryland, U.S.A.
- Year and Date
  2007-03-05
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] Na^+/Mg^<2+> exchange as an active extrusion pathway of cellular mangesium2006
- Author(s)
  Konishi, M., Tashiro, M. and Tursun, P.
- Organizer
  11th International Magnesium Symposium
- Place of Presentation
  Mie, Japan
- Year and Date
  2006-10-25
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] Na^+/Mg^<2+> exchange in rat ventricular myocytes2006
- Author(s)
  Konishi, M., Tashiro, M. and Tursun, P.
- Organizer
  6th Congress of the Federation of Asian and Oceanian Physiological Societies
- Place of Presentation
  Seoul, Korea
- Year and Date
  2006-10-17
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] Na^+-dependent Mg^<2+> efflux is largely inhibited in deenergized heart cells2006
- Author(s)
  Tashiro, M., Watanabe, M. and Konishi, M.
- Organizer
  11th International Magnesium Symposium
- Place of Presentation
  Mie, Japan
- Year and Date
  2006-10-24
- Data Source
  KAKENHI-PROJECT-18390066
[Presentation] Intracellular magnesium concentration is maintained by sodium/magnesium exchange in cardiac myocytes2006
- Author(s)
  Konishi, M., Tursun, P. and Tashiro, M.
- Organizer
  2^<nd> world congress of International Academy of Cardiovascular Sciences
- Place of Presentation
  Hokkaido, Japan
- Year and Date
  2006-07-14
- Data Source
  KAKENHI-PROJECT-18390066

1. WATANABE Masaru (60191798)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. MIYAZAKI Takefuimi (60147212)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. NAKAYAMA Shinsuke (30192230)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. KURIHARA Satoshi (90057026)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HIROSE Kenzo (00292730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YOKOYAMA Michiko (20398762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
7. HONGO Kenichi (00256447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 國分眞一朗 (20153520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山下俊一 (60256865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高木都 (00033358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 鈴木光 (80037548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小室輝昌 (20037386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 鳥橋茂子 (90112961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中村桂一郎 (20172398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Konishi Masato 小西 真人

KONISHI Masato 小西 真人

小西 真人

Research Projects

Research Products

Co-Researchers

Regulation of intracellular magnesium concentrationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

自律神経系ペースメーカ機構の拡がり

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of magnesium transporter molecules and functional analysis with high temporal/spatial resolution.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞内局所イベントが作り出すグローバルな細胞・組織機能-改良型ケイジドCa^<2+>多光子レーザー分解および局所Ca^<2+>定量法の確立と応用-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and quantitative analysis of the cell membrane MgィイD1[2+]ィエD1 transporter in cardiac and smooth muscles.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋・平滑筋細胞におけるCa遊離・収縮の細胞内Mgによる制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血管平滑筋細胞内Mgの変動とその生理的役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Novel Method to Quantify Intracellular Free Calcium Concentration in Muscle Cells with a Fluorescent Indicator.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Optical Measurements of Intracellular Free Magnesium Concentration in Skeletal and Cardiac Muscle CardiacPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

光学的方法による単一心筋細胞内遊離Ca濃度測定と興奮-収縮連関機構の解明

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Study of intracellular calcium movement by time resolved image processing method.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differential effects of an expected actin-tropomyosin binding region of heat shock protein 20 on the relaxation in skinned carotid artery and taenia cecum from guinea pig2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Metabolic inhibition largely diminishes Na^+-Mg^<2+> exchange in rat ventricular myocytes.2007

Author(s)

Journal Title

Data Source

Konishi Masato 小西真人

KONISHI Masato 小西真人

小西真人