OKANOUE Takeshi 岡上武

Researcher Number	20150568
Affiliation (based on the past Project Information) *help	2016 – 2020: 京都府立医科大学, 医学(系)研究科(研究院), 教授 2003 – 2006: 京都府立医科大学, 医学研究科, 教授 2003: Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Professor, 大学院・医学研究科, 教授 2002: Kyoto Prefectural University of Medicine, Professor, 医学部, 教授 1998 – 2001: 京都府立医科大学, 医学部, 助教授 … More 1993 – 1995: 京都府立医科大学, 医学部, 助教授 1989 – 1991: Kyoto Prefectural University of Medicine, Department of Medicine, Associate Professor, 医学部, 助教授 1987 – 1988: 京都府立医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Digestive surgery / Gastroenterology
Keywords	Principal Investigator 肝細胞中間径フィラメント / 免疫電顕 / レトロウイルス / 肝細胞癌 / サイトケラチン / 中間径フィラメント / B型肝炎ウイルス / B型肝炎 / 肝癌 / 肝細胞 … More / 肝癌細胞株 / Immunoelectron microscopy / Desmosome / Pericanalicular sheath / Microfilament / Intermediate filament / Cytoskeleton of hepatocyte / Intrahepatic cholestasis / 急速凍結ディープエッチングレプリカ法 / 走査電顕 / 免疫螢光法 / 胆細胞細胞骨格 / デスモプラキン / 肝細胞マイクロフィラメント / 肝内胆汁うつ滞 / デスキソ-ム / pericanalicular sheath / マイクロフィラメント / 肝細胞細胞骨格 / 胆汁うっ滞 / deletion / gene amplification / genome / hepatocelluar carcinoma / アレイ / 分子標的 / 遺伝子 / 欠失 / 遺伝子増幅 / ゲノム / methylation / insulator / bone marrow cell / hepatocyte / retrovirus / インシュレーター / メチル化 / インシュレータ / 骨髄細胞 / hepatocarcinogenesis / ribavitin / interferon / hepatitis C virus / YMDD motif mutant / lamivudine / integration / hepatitis B virus / Alu-PCR / 肝発癌抑制 / HBV / C型慢性肝炎 / C型肝炎 / HCVdynamics / 肝発癌 / リバビリン / インターフェロン / C型肝炎ウイルス / YMDD変異ウイルス / ラミブジン / 遺伝子組み込み / two dimensional immunodiffusion / cytokeratin / intermediate fimament of hepatocyte / hepatocellular carcinoma / 二次元電気泳動 / Change of Cytokeratin in Mallory Body Formation / Phenotypic Change of Intermediate Filament / Mallory Body and Intermediate Filament / Ubiquitination of Mallory Body / プロテアソ-ム / ユ-ビキチン / ユビキチン / マロリ-体 / マロリ-体形成におけるサイトケラチンの変化 / 中間径フィラメントのフエノタイプの変化 / マロリ-体と中間径フィラメント / マロリ-体のユビキチン化 / micro RNA / microRNA / レトロウイルs / 癌遺伝子 / ベクター / 肝臓 / LTR / レトロウイルスベクター / 副腎皮質ステロイド剤 / アルコール性肝炎 / 自己免疫性肝炎 / ウイルス性肝炎 / 好中球 / リンパ球 / 細胞接着分子 / 炎症性細胞浸潤 … More Except Principal Investigator Alu-PCR / hepatitis B virus / lamivudine / peptide nucleic acid / viral resistance / hepatocellular carcinoma / chronic hepatitis / HBV / 肝発癌 / PNA / 耐性ウイルス / ラミブジン / 肝癌 / 慢性肝炎 / B型肝炎ウイルス / 癌抑制遺伝子 / RUNX3 / 胃癌 / IgM / NAFLD / NASH / 脂肪肝 / AIM / NASH肝癌 / liver carcinogenesis / integration / MLL4 / hTERT / 組み込み / 薬剤耐性 / PCR clamping / 薬剤耐性ウイルス / ウイルス組み込み / 遺伝子診断 Less

Elucidation of the mechanism required for AIM activation, and its therapeutic application to NASH-induced hepatocellular carcinoma
- Principal Investigator
  
  宮崎徹
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
胃癌新規癌抑制遺伝子RUNX3の異常を伴う胃癌前駆細胞の同定と遺伝子診断への応用
- Principal Investigator
  
  阪倉長平
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Identification of molecular target genes for therapy in hepatocellular carcinoma.Principal Investigator
- Principal Investigator
  
  YASUI Kohichiroh, 岡上武
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
Search for novel genomic regions related to liver carcinogenesis by using a hepatitis B virus integration site as a genetic probe
- Principal Investigator
  
  MINAMI Masahito
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
B型肝炎ウイルスのコードするmicroRNAの検索Principal Investigator
- Principal Investigator
  
  岡上武
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
胃癌新規癌抑制遺伝子RUNX3の異常を伴う胃癌前駆細胞の同定と遺伝子診断への応用
- Principal Investigator
  
  阪倉長平
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Treatment of chronic hepatitis B for the prevention of development of hepatocellular carcinoma and analyses of hepatitis B virus insertional mutagenesis as a first hit during multistep liver carcinogenesis.
- Principal Investigator
  
  MINAMI Masahito
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Graduate School of Medical Science, Kyoto Prefectural University of Medicine
HCV core蛋白を標的とした新たな遺伝子治療戦略の可能性Principal Investigator
- Principal Investigator
  
  岡上武
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
Treatment of hepatitis B virus without inducing antiviral resistant viruses and analyses of HBV integration at an early stage of infection before development of hepatocellular carcinoma.
- Principal Investigator
  
  MINAMI Masahito
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Graduate School of Medical Science, Kyoto Prefectural University of Medicine
Gene transfer to hematopoietic stem cells by a newly-designed retroviral vectors and expression of transgenes in the liverPrincipal Investigator
- Principal Investigator
  
  OKANOUE Takeshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
肝細胞で高発現する新しいレトロウイルスベクターの開発Principal Investigator
- Principal Investigator
  
  岡上武
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
Treatment of chronic hepatitis and analysis of HBV integration for the purpose of prevention of hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  OKANOUE Takeshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
炎症性細胞の肝内浸潤過程の動的解析-接着分子とshear stressを中心に-Principal Investigator
- Principal Investigator
  
  岡上武
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
Significance of intermediate filament in HCCPrincipal Investigator
- Principal Investigator
  
  OKANOUE Takeshi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
Metabolism of the protein constituting Mallory bodyPrincipal Investigator
- Principal Investigator
  
  OKANOUE Takeshi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine
The study of cholestasis using immunoelectron microscopy and rapid freezing deep-etching replicaPrincipal Investigator
- Principal Investigator
  
  OKANOUE Takeshi
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine

All 2017 2008 2007 2006 2004 2003 2002 Other

All Journal Article Presentation Book Patent

[Book] コンセンサス肝疾患B型肝炎・C型肝炎の治療.坪内博仁, 監修2007
- Author(s)
  南祐仁, 岡上武
- Publisher
  日本メディカルセンター,東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Book] 臨床に直結する肝・胆・膵疾患治療のエビデンス.跡見裕, 上村直実, 白鳥敬子, 正木尚彦, 編集2007
- Author(s)
  南祐仁, 岡上武
- Publisher
  文光堂,東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Book] 最新肝臓病の診断と治療2006
- Author(s)
  岡上武
- Total Pages
  132
- Publisher
  銀海舎
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390223
[Book] 最新肝臓病の診断と治療2006
- Author(s)
  岡上武
- Total Pages
  132
- Publisher
  銀海舎(東京)
- Data Source
  KAKENHI-PROJECT-18390223
[Journal Article] Activation of apoptosis inhibitor of macrophage is a sensitive diagnostic marker for NASH-associated hepatocellular carcinoma2017
- Author(s)
  Koyama Noriyuki、Yamazaki Tomoko、Kanetsuki Yuka、Hirota Jiro、Asai Tomohide、Mitsumoto Yasuhide、Mizuno Masayuki、Shima Toshihide、Kanbara Yoshihiro、Arai Satoko、Miyazaki Toru、Okanoue Takeshi
- Journal Title
  
  The Japanese Society of Gastroenterology
  
  Volume: なし Issue: 6 Pages: 770-779
- DOI
  10.1007/s00535-017-1398-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17J03519, KAKENHI-PROJECT-16H06389
[Journal Article] Guidelines for the antiviral therapy of hepatitis C virus carriers with normal serum aminotransferase based on platelet counts2008
- Author(s)
  T.Okanoue
- Journal Title
  
  Hepatol Res. 38
  
  Pages: 27-36
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390223
[Journal Article] Guidelines for the antiviral therapy of hepatitis C virus carriers with normal serum aminotransferase based on platelet counts. 2008;382008
- Author(s)
  Okanoue, T, Itoh, Y, Minami, M, Hashimoto, H, Yasui, K, Yotsuyanagi, H, Takehara, T, Kumada, T, Tanaka, E, Nishiguchi, S, Izumi, N, Sata, M, Onji, M, Yamada, G, Okita, K, Kumada, H
- Journal Title
  
  Hepatol Res 38
  
  Pages: 27-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390223
[Journal Article] Evidence of oxidative stress as a cofactor in the development of insulin resistance in patients with chronic hepatitis C. Hepatol Res2008
- Author(s)
  Mitsuyoshi, H, Itoh, Y, Sumida, Y, Minami, M, Yasui, K, Nakashima, T, Okanoue, T
- Journal Title
  
  Hepatol Res 38
  
  Pages: 348-353
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390223
[Journal Article] Guidelines for the antiviral therapy of hepatitis C virus carriers with normal serum aminotransferase based on platelet counts.2008
- Author(s)
  T. Okanoue
- Journal Title
  
  Hepatol Res. 38
  
  Pages: 27-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390223
[Journal Article] CREB3L4, INTS3, and SNAPAP are targets for the 1q21 amplicon frequently detected in hepatocellular carcinoma2008
- Author(s)
  Inagaki, Y, Yasui, K, Endo, M, Nakajima, T, Zen K, Tsuji, K, Minami, M, Tanaka, S, Taniwaki, M, Itoh, Y, Arii, S, Okanoue, T
- Journal Title
  
  Cancer Genet Cytogenet 180
  
  Pages: 30-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390223
[Journal Article] Management of HBV infection(in Japan)2007
- Author(s)
  Minami, M., Okanoue, T
- Journal Title
  
  Hepatology Research 37(s1)
  
  Pages: 579-882
- NAID
  10019566326
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Low serum level of hepatitis B core-related antigen indicates unlikely reactivation of hepatitis after cessation of lamivudine therapy2007
- Author(s)
  Matsumoto A, Tanaka E, Minami M, Okanoue T, Yatsuhashi H, Nagaoka S, Suzuki F, Kobayashi M, Chayama K, Imamura M, Yotsuyanagi H, Nakaoka S, Maki N, Kawata S, Kumada H, Iino S, Kiyosawa K.
- Journal Title
  
  Hepatology Research 37(8)
  
  Pages: 661-666
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Management of HBV infection in Japan.2007
- Author(s)
  Minami M, Okanoue T.
- Journal Title
  
  Hepatol Res. 37
- NAID
  10019566326
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Management of HBV infection in Japan2007
- Author(s)
  Minami M, Okanoue T.
- Journal Title
  
  Hepatology Research 37(s1)
- NAID
  10019566326
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Low serum level of hepatitis B core-related antigen indicates unlikely reactivation of hepatitis after cessation of lamivudine therapy2007
- Author(s)
  Matsumoto, A., Tanaka, E., Minami, M., Okanoue, T., Yatsuhashi, H., Nagaoka, S., Suzuki, F., Kobayashi, M., Chayama, K., Imamura, M., Yotsuyanagi, H., Nakaoka, S., Maki, N., Kawata, S., Kumada, H., Iino, S., Kiyosawa, K
- Journal Title
  
  Hepatology Research 37(8)
  
  Pages: 661-666
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Update of research and management of hepatitis B.2006
- Author(s)
  Okanoue T, Minami M.
- Journal Title
  
  Journal of Gastroenterology 41-2
  
  Pages: 107-118
- NAID
  10017420911
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590616
[Journal Article] Measurement of hepatitis B virus core-related antigen is valuable for identifying patients who are at low risk of lamivudine resistance2006
- Author(s)
  Tanaka E, Matsumoto A, Suzuki F, Kobayashi M, Mizokami M, Tanaka Y, Okanoue T, Minami M, Chayama K, Imamura M, Yatsuhashi H, Nagaoka S, Ybtsuyanagi H, Kawata S, Kimura T, Maki N, Iino S, Kiyosawa K; HBV Core-Related Antigen Study Group
- Journal Title
  
  Liver International 26(1)
  
  Pages: 90-96
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Unusually high incidence of hepatitis B virus integration into the MLL gene in hepatocellular carcinoma.2006
- Author(s)
  Minami M, Fujii K, Miyagawa M, Okanoue T
- Journal Title
  
  Clinical Cancer Research 12
  
  Pages: 3549-3549
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Umusually high incidence of hepatitis B virus integration into the MLL gene in hepatocellular carcinoma2006
- Author(s)
  Minami M, Fujii K, Miyagawa M, Okanoue T.
- Journal Title
  
  Clinical Cancer Research 12(11Pt1)
  
  Pages: 3549-3550
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Update of research and management of hepatitis B2006
- Author(s)
  Okanoue T, Minami M.
- Journal Title
  
  Journal of Gastroenterology 41(2)
  
  Pages: 107-118
- NAID
  10017420911
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Update of research and management of hepatitis B.2006
- Author(s)
  Okanoue T, Minami M.
- Journal Title
  
  Journal of Gastroenterology 41・2
  
  Pages: 107-118
- NAID
  10017420911
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590616
[Journal Article] HBV Core-Related Antigen Study Group. Measurement of hepatitis B virus core-related antigen is valuable for identifying patients who are at low risk of lamivudine resistance2006
- Author(s)
  Tanaka, E, Matsumoto, A, Suzuki, F, Kobayashi, M, Mizokami, M, Tanaka, Y, Okanoue, T, Minami, M, Chayama, K, Imamura, M, Yatsuhashi, H, Nagaoka, S, Yotsuyanagi, H, Kawata, S, Kimura, T, Maki, N, Iino, S, Kiyosawa, K
- Journal Title
  
  Liver International 26(1)
  
  Pages: 90-96
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Update of research and management of hepatitis B.2006
- Author(s)
  Okanoue T, Minami M
- Journal Title
  
  Update of research and management of hepatitis B. 41・2
  
  Pages: 107-118
- NAID
  10017420911
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Prediction of breakthrough hepatitis due to lamivudine-resistant hepatitis B virus by a sensitive semiquantitative assay using peptide nucleic acids2006
- Author(s)
  Mori K, Minami M, Kirishima T, Kunimoto K, Okita M, Nakayama M, Makiyama A, Yamaoka J, Nakajima T, Yasui K, Itoh Y, Okanoue T.
- Journal Title
  
  Intervirology 49(5)
  
  Pages: 274-280
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Update of research and management of hepatitis B.2006
- Author(s)
  Okanoue T, Minami M.
- Journal Title
  
  Journal of Gastroenterology 41(2)
  
  Pages: 107-118
- NAID
  10017420911
- Data Source
  KAKENHI-PROJECT-16590616
[Journal Article] Prediction of breakthrough hepatitis due to lamivudine-resistant hepatitis B virus by a sensitive semiquantitative assay using peptide nucleic acides.2006
- Author(s)
  Mori K, Minami M, Kirishima T, Kunimoto K, Okita M, Nakayama M, Makiyama A, Yamaoka J, Nakajima T, Yasui K, Itoh Y, Okanoue T
- Journal Title
  
  Intervirology 49・5
  
  Pages: 274-280
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Measurement of hepatitis B virus core-related antigen is valuable for identifying patients who are at low risk of lamivudine resistance.2006
- Author(s)
  Tanaka E, Matsumoto A, Suzuki F, Kobayashi M, Mizokami M, Tanaka Y, Okanoue T, Minami M, Chayama K, Imamura M, Yatsuhashi H, Nagaoka S, Yotsuyanagi H, Kawata S, Kimura T, Maki N, Iino S, Kiyosawa K
- Journal Title
  
  Liver International 26・1
  
  Pages: 90-96
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Update of research and management of hepatitis B2006
- Author(s)
  Okanoue, T., Minami, M
- Journal Title
  
  Journal of Gastroenterology 41(2)
  
  Pages: 107-118
- NAID
  10017420911
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Prediction of breakthrough hepatitis due to lamivudine-resistant hepatitis B virus by a sensitive semiquantitative assay using peptide nucleic acids2006
- Author(s)
  Mori, K., Minami, M., Kirishima, T., Kunimoto, K., Okita, M., Nakayama, M., Makiyama, A., Yamaoka, J., Nakajima, T., Yasui, K., Itoh, Y., Okanoue, T
- Journal Title
  
  Intervirology 49(5)
  
  Pages: 274-280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Unusually high incidence of hepatitis B virus integration into the MLL gene in hepatocellular carcinoma2006
- Author(s)
  Minami, M., Fujii, K., Miyagawa, M., Okanoue, T
- Journal Title
  
  Clinical Cancer Research 12(11 Pt 1)
  
  Pages: 3549-3550
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Journal Article] Hepatitis B virus reactivation in a patient undergoing steroid-free chemotherapy.2004
- Author(s)
  Shimizu D, Nomura K, Matsumoto Y, Ueda K, Yamaguchi K, Minami M, Itoh Y, Horiike S, Morita A, Taniwaki M, Okanoue T
- Journal Title
  
  World Journal of Gastroenterology 10
  
  Pages: 2301-2302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570495
[Journal Article] Hepatitis B virus DNA in liver, serum, and peripheral blood mononuclear cells after the clearance of serum hepatitis B virus surface antigen.2004
- Author(s)
  Murakami Y, Minami M, Daimon Y, Okanoue T.
- Journal Title
  
  Journal of Medical Virology 72
  
  Pages: 203-214
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570495
[Journal Article] Hepatitis B virus reactivation in a patient undergoing steroid-free chemotherapy.2004
- Author(s)
  Shimizu D, Nomura K, Matsumoto Y, Ueda K, Yamaguchi K, Minami M, Itoh Y, Horiike S, Morita A, Taniwaki M, Okanoue T.
- Journal Title
  
  World Journal of Gastroenterology 10
  
  Pages: 2301-2302
- Data Source
  KAKENHI-PROJECT-16590616
[Journal Article] Hepatitis B virus reactivation in a patient undergoing steroid-free chemotherapy.2004
- Author(s)
  Shimizu D, Nomura K, Matsumoto Y, Ueda K, Yamaguchi K, Minami M, Itoh Y, Horiike S, Morita A, Taniwaki M, Okanoue T.
- Journal Title
  
  World Journal of Gastroenterology 10
  
  Pages: 2301-2302
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570495
[Journal Article] Hepatitis B virus DNA in liver, serum, and peripheral blood mononuclear cells after the clearance of serum hepatitis B virus surface antigen.2004
- Author(s)
  Murakami Y, Minami M, Daimon Y, Okanoue T
- Journal Title
  
  Journal of Medical Virology 72
  
  Pages: 203-214
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570495
[Journal Article] Hepatitis B virus DNA in liver, serum, and peripheral blood mononuclear cells after the clearance of serum hepatitis B virus surface antigen.2004
- Author(s)
  Murakami Y, Minami M, Daimon Y, Okanoue T.
- Journal Title
  
  Journal of Medical Virology 72
  
  Pages: 203-214
- Data Source
  KAKENHI-PROJECT-16590616
[Journal Article] Lamivudine therapy for Japanese patients with cirrhosis B.2003
- Author(s)
  Okanoue T, Mori K, Kirishima T, Kunimoto K, Yasui K, Itoh Y, Minami M.
- Journal Title
  
  Intervirology 46
  
  Pages: 394-399
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570495
[Journal Article] Detection of YMDD mutant using a novel sensitive method in chronic liver disease type B patients before and during lamivudine treatment.2002
- Author(s)
  Kirishima T, Okanoue T, Daimon Y, Itoh Y, Nakamura H, Morita A, Toyama T, Minami M.
- Journal Title
  
  Journal of Hepatology 37
  
  Pages: 259-265
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570495
[Journal Article] Hepatitis B virus-related insertional mutagenesis in chronic hepatitis B patients as an early drastic genetic change leading to hepatocarcinogenesis.
- Author(s)
  Minami M, Daimon Y, Mori K, Takashima H, Nakajima T, Itoh Y, Okanoue T
- Journal Title
  
  Oncogene (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570495
[Journal Article] Hepatitis B virus-related insertional mutagenesis in chronic hepatitis B patients as an early drastic genetic change leading to hepatocarcinogenesis.
- Author(s)
  Minami M, Daimon Y, Mori K, Takashima H, Nakajima T, Itoh Y, Okanoue T.
- Journal Title
  
  Oncogene (in press)
- Data Source
  KAKENHI-PROJECT-16590616
[Journal Article] Hepatitis B virus-related insertional mutagenesis in chronic hepatitis B patients as an early drastic genetic change leading to hepatocarcinogenesis.
- Author(s)
  Minami M, Daimon Y, Mori K, Takashima H, Nakajima T, Itoh Y, Okanoue T.
- Journal Title
  
  Oncogene (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570495
[Patent] 特許権2002
- Inventor(s)
  南祐仁, 桐島寿彦, 岡上武, 向出雅一
- Industrial Property Rights Holder
  株式会社エスアールエル
- Industrial Property Number
  2002-244392
- Filing Date
  2002-08-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570495
[Presentation] Specific activation of apoptosis inhibitor of macrophage (AIM) in patients with NASH-associated hepatocellular carcinoma2017
- Author(s)
  Tomoko Yamazaki, Toru Miyazaki, Takeshi Okanoue
- Organizer
  AASLD The Liver Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06389
[Presentation] HBV reactivation with altered HBs antigenicity in a patient who received rituximab2007
- Author(s)
  Miyagawa M, Minami M, Hashimoto H, Sendo R, Fujii K, Ito Y, Shimizu D, Matsumoto Y, Taniwaki M, Okanoue T.
- Organizer
  15th Asian Pacific Association for the Study of the Liver Conference
- Place of Presentation
  Kyoto
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Presentation] MAPK7Identified as a Probable Target for Amplification at 17p11 in Hepatocellular Carcinoma2007
- Author(s)
  Keika, Zen, Kohichiroh, Yasui, Tomoaki, Nakajima, Yoshikazu, Inagaki, Shoji, Mitsufuji, Shinji, Tanaka, Masafumi, Taniwaki, Yoshito, Itoh, Shigeki, Arii, Takeshi, Okanoue
- Organizer
  The liver meeting 2007 (AASLD)
- Place of Presentation
  Boston, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390223
[Presentation] Lamivudine with sequential interferon therapy in Japanese patients with chronic hepatitis type B2007
- Author(s)
  Minami M, Mori K, Fujii K, Miyagawa M, Itoh Y, Okanoue T.
- Organizer
  15th Asian Pacific Association for the Study of the Liver Conference
- Place of Presentation
  Kyoto
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Presentation] Identification of cancerrelated genes using HBV integration as a sequencetag2006
- Author(s)
  Minami M, Fujii K, Miyagawa M, Itoh Y, Okanoue T.
- Organizer
  Annual Meeting of the American Association for the Study of Liver Disease(AASLD)
- Place of Presentation
  Boston,USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Presentation] 長期寛解を目指したラミブジン・インターフェロン併用療法. パネルディスカッション1;コンセンサスミーティング・B型肝炎の治療2006
- Author(s)
  南祐仁, 岡上武
- Organizer
  第48回日本消化器病学会大会, 第10回日本肝臓学会大会(DDW-Japan2006)
- Place of Presentation
  札幌
- Year and Date
  2006-10-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Presentation] HBV組み込みによるヒト遺伝子の発現修飾と肝細胞増殖. ワークショップ5;肝炎ウイルスによる肝障害機序と肝発癌機序の解明2006
- Author(s)
  南祐仁, 藤井恒太, 岡上武
- Organizer
  第92回日本消化器病学会総会
- Place of Presentation
  北九州
- Year and Date
  2006-04-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Presentation] 組み込み旺BVをタグとした肝発癌関連遺伝子の同定. ワークショップ1;ウイルス性肝炎研究の最先端2006
- Author(s)
  南祐仁, 藤井恒太, 宮川昌巳, 伊藤義人, 森康二郎, 岡上武
- Organizer
  第42回日本肝臓学会総会
- Place of Presentation
  京都
- Year and Date
  2006-05-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Presentation] Management of HBV infection in Japan2006
- Author(s)
  Minami, M., Okanoue, T
- Organizer
  International Symposium on HBV
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-05-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Presentation] Management of HBV infection in Japan2006
- Author(s)
  Minami M, Okanoue T.
- Organizer
  International Symposium on HBV
- Place of Presentation
  Kyoto
- Year and Date
  2006-05-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Presentation] 悪性リンパ腫の治療後に発症したHBs抗原陰性,HBVDNA陽性の急性肝炎2006
- Author(s)
  宮川昌巳, 南祐仁, 橋本宏明, 森康二郎, 藤井恒太, 伊藤義人, 清水大介, 松本洋典, 谷脇雅史, 岡上武
- Organizer
  第42回日本肝臓学会総会
- Place of Presentation
  京都
- Year and Date
  2006-05-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590742
[Presentation] Identification of cancer-related genes using HBV integration as a sequence tag2006
- Author(s)
  Minami, M., Fujii, K., Miyagawa, M., Itoh, Y., Okanoue, T
- Organizer
  Annual Meeting of the American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  Boston, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590742

1. ITOH Yoshito (70244613)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. ITOH Katsuhiko (90281097)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. MINAMI Masahito (60326220)

# of Collaborated Projects: 3 results

# of Collaborated Products: 43 results
4. YASUI Kohichiroh (30323695)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 阪倉長平 (10285257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 奥田司 (30291587)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MORIOKA Hiroyuki (50079951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 宮崎徹 (30396270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

OKANOUE Takeshi 岡上 武

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism required for AIM activation, and its therapeutic application to NASH-induced hepatocellular carcinoma

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胃癌新規癌抑制遺伝子RUNX3の異常を伴う胃癌前駆細胞の同定と遺伝子診断への応用

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Identification of molecular target genes for therapy in hepatocellular carcinoma.Principal Investigator

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Search for novel genomic regions related to liver carcinogenesis by using a hepatitis B virus integration site as a genetic probe

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B型肝炎ウイルスのコードするmicroRNAの検索Principal Investigator

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胃癌新規癌抑制遺伝子RUNX3の異常を伴う胃癌前駆細胞の同定と遺伝子診断への応用

Principal Investigator

Project Period (FY)

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Research Institution

Treatment of chronic hepatitis B for the prevention of development of hepatocellular carcinoma and analyses of hepatitis B virus insertional mutagenesis as a first hit during multistep liver carcinogenesis.

Principal Investigator

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HCV core蛋白を標的とした新たな遺伝子治療戦略の可能性Principal Investigator

Principal Investigator

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Treatment of hepatitis B virus without inducing antiviral resistant viruses and analyses of HBV integration at an early stage of infection before development of hepatocellular carcinoma.

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Gene transfer to hematopoietic stem cells by a newly-designed retroviral vectors and expression of transgenes in the liverPrincipal Investigator

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肝細胞で高発現する新しいレトロウイルスベクターの開発Principal Investigator

Principal Investigator

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Treatment of chronic hepatitis and analysis of HBV integration for the purpose of prevention of hepatocellular carcinomaPrincipal Investigator

Principal Investigator

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炎症性細胞の肝内浸潤過程の動的解析-接着分子とshear stressを中心に-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

OKANOUE Takeshi 岡上武

[Book] 最新肝臓病の診断と治療2006

[Book] 最新肝臓病の診断と治療2006